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The map label for this gene is manA [H]

Identifier: 23100220

GI number: 23100220

Start: 2837010

End: 2837969

Strand: Reverse

Name: manA [H]

Synonym: OB2765

Alternate gene names: 23100220

Gene position: 2837969-2837010 (Counterclockwise)

Preceding gene: 23100221

Following gene: 23100214

Centisome position: 78.17

GC content: 36.56

Gene sequence:

>960_bases
ATGTATCAAGAACCAATTTTCTTAGAACCAGTCATGCAAGAAAGAATATGGGGAGGTAAAAAACTAAATCAATTATTTGG
ATATAAGAGCTCATATGAGCAAACAGGAGAAGCATGGGTGATATCTGCGCATAAAAATGGGCCGAATAAAATTATAAATG
GTCCTTTACAAGGGAGTACACTTGTAGATGCGTGGGAAAATCATGGGGAGCTGTTTAATAAACAACAGGATTCGAATGAT
GCTTATCCATTACTGATAAAAATATTAGATGCTAATGATGATTTATCTGTTCAAGTGCATCCTGACGATACATATGCACG
GGAAGTAGAAAATGAATCTTACGGGAAAACAGAATGCTGGTATGTTCTAGATGCAGAGCCTGATGCGGAGCTTATTTTAG
GTCACCATGCAGCGACAAAAGAAGAATTAAATCAGATGATTGATCAAGGAGAGTGGGATCAATTATTAAAACGAGTACCC
GTTGCAAAGGGGGATTTCGTTCATGTGCCTAGCGGTACTATACATGCAATCGGAAAAGGGATCGTTATTCTCGAGACACA
GCAAAGTTCCGATGTTACATATCGTGTGTATGATTATGATCGTAAAGATTCAGAAGGGAATAAACGTGAACTGCATTTAC
AAAAAGCGAAAGAAGTGACGATGGTTCCGCACCAAGACGTTCAAATTAAACCAATAGAAGAAGTGCAAGAGGACTTATCG
ATTCGAAAGTTAATTGAAGCGGAATATTTTACAGTTTATCATTGGGAAATACAAGGAAATGTAACTAAAATTCTCGATAA
AGACTTTTTACAAATAAGTGTGATTGAAGGAACAGGTACAGTTAAGATAGGTGATAAAAAGTTTACGATTGAGAAAGGAT
CAAACTTTATATTGCCTCAAGGAATAAAAACATATGAACTGGAAGGAAATGCAGAGTGTATCGTATCTCATCCTTCTTAA

Upstream 100 bases:

>100_bases
TTAAATTAGTTGCAAATTCCAGTGCTGAAAATCAAACAAGGAAACATCCAGATTTGTTATAATAATAAGTATACAAAAGC
GTTTGAGGGGATGAAAAAGC

Downstream 100 bases:

>100_bases
TATCGAAAGGGAAATTAACGCTTTAATTGAGTATTAGTGAGTCTCCAAGTGACGGAGACTCGCTTTTTTTTCTAGGTCTG
CTTTAAACTTGCTCAATAAT

Product: mannose-6-phosphate isomerase

Products: NA

Alternate protein names: Phosphohexomutase; Phosphomannose isomerase; PMI [H]

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MYQEPIFLEPVMQERIWGGKKLNQLFGYKSSYEQTGEAWVISAHKNGPNKIINGPLQGSTLVDAWENHGELFNKQQDSND
AYPLLIKILDANDDLSVQVHPDDTYAREVENESYGKTECWYVLDAEPDAELILGHHAATKEELNQMIDQGEWDQLLKRVP
VAKGDFVHVPSGTIHAIGKGIVILETQQSSDVTYRVYDYDRKDSEGNKRELHLQKAKEVTMVPHQDVQIKPIEEVQEDLS
IRKLIEAEYFTVYHWEIQGNVTKILDKDFLQISVIEGTGTVKIGDKKFTIEKGSNFILPQGIKTYELEGNAECIVSHPS

Sequences:

>Translated_319_residues
MYQEPIFLEPVMQERIWGGKKLNQLFGYKSSYEQTGEAWVISAHKNGPNKIINGPLQGSTLVDAWENHGELFNKQQDSND
AYPLLIKILDANDDLSVQVHPDDTYAREVENESYGKTECWYVLDAEPDAELILGHHAATKEELNQMIDQGEWDQLLKRVP
VAKGDFVHVPSGTIHAIGKGIVILETQQSSDVTYRVYDYDRKDSEGNKRELHLQKAKEVTMVPHQDVQIKPIEEVQEDLS
IRKLIEAEYFTVYHWEIQGNVTKILDKDFLQISVIEGTGTVKIGDKKFTIEKGSNFILPQGIKTYELEGNAECIVSHPS
>Mature_319_residues
MYQEPIFLEPVMQERIWGGKKLNQLFGYKSSYEQTGEAWVISAHKNGPNKIINGPLQGSTLVDAWENHGELFNKQQDSND
AYPLLIKILDANDDLSVQVHPDDTYAREVENESYGKTECWYVLDAEPDAELILGHHAATKEELNQMIDQGEWDQLLKRVP
VAKGDFVHVPSGTIHAIGKGIVILETQQSSDVTYRVYDYDRKDSEGNKRELHLQKAKEVTMVPHQDVQIKPIEEVQEDLS
IRKLIEAEYFTVYHWEIQGNVTKILDKDFLQISVIEGTGTVKIGDKKFTIEKGSNFILPQGIKTYELEGNAECIVSHPS

Specific function: Unknown

COG id: COG1482

COG function: function code G; Phosphomannose isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR001250
- InterPro:   IPR014628
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01238 PMI_typeI [H]

EC number: =5.3.1.8 [H]

Molecular weight: Translated: 36268; Mature: 36268

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQEPIFLEPVMQERIWGGKKLNQLFGYKSSYEQTGEAWVISAHKNGPNKIINGPLQGST
CCCCCEEHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCEECCCCCCCC
LVDAWENHGELFNKQQDSNDAYPLLIKILDANDDLSVQVHPDDTYAREVENESYGKTECW
HHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCEEEEECCCCHHHHHCCCCCCCCEEEE
YVLDAEPDAELILGHHAATKEELNQMIDQGEWDQLLKRVPVAKGDFVHVPSGTIHAIGKG
EEEECCCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHCCCCCCCEEECCCCCEEECCCC
IVILETQQSSDVTYRVYDYDRKDSEGNKRELHLQKAKEVTMVPHQDVQIKPIEEVQEDLS
EEEEEECCCCCCEEEEEECCCCCCCCCCEEEEEECCCCEEECCCCCCEECCHHHHHHHHH
IRKLIEAEYFTVYHWEIQGNVTKILDKDFLQISVIEGTGTVKIGDKKFTIEKGSNFILPQ
HHHHHCCCEEEEEEEEECCCHHHHHCCCCEEEEEEECCCEEEECCEEEEEECCCCEECCC
GIKTYELEGNAECIVSHPS
CCEEEEECCCCEEEEECCC
>Mature Secondary Structure
MYQEPIFLEPVMQERIWGGKKLNQLFGYKSSYEQTGEAWVISAHKNGPNKIINGPLQGST
CCCCCEEHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCEECCCCCCCC
LVDAWENHGELFNKQQDSNDAYPLLIKILDANDDLSVQVHPDDTYAREVENESYGKTECW
HHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCEEEEECCCCHHHHHCCCCCCCCEEEE
YVLDAEPDAELILGHHAATKEELNQMIDQGEWDQLLKRVPVAKGDFVHVPSGTIHAIGKG
EEEECCCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHCCCCCCCEEECCCCCEEECCCC
IVILETQQSSDVTYRVYDYDRKDSEGNKRELHLQKAKEVTMVPHQDVQIKPIEEVQEDLS
EEEEEECCCCCCEEEEEECCCCCCCCCCEEEEEECCCCEEECCCCCCEECCHHHHHHHHH
IRKLIEAEYFTVYHWEIQGNVTKILDKDFLQISVIEGTGTVKIGDKKFTIEKGSNFILPQ
HHHHHCCCEEEEEEEEECCCHHHHHCCCCEEEEEEECCCEEEECCEEEEEECCCCEECCC
GIKTYELEGNAECIVSHPS
CCEEEEECCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]