Click here to switch to the map view.

The map label for this gene is manR [H]

Identifier: 23100211

GI number: 23100211

Start: 2826476

End: 2828533

Strand: Reverse

Name: manR [H]

Synonym: OB2756

Alternate gene names: 23100211

Gene position: 2828533-2826476 (Counterclockwise)

Preceding gene: 23100212

Following gene: 23100210

Centisome position: 77.91

GC content: 34.99

Gene sequence:

>2058_bases
TTGGGAGAAAGAGAAGAGCAGATTCTTAACGAATTAATAAAAGATACAAGTATCACAAGCTCGAAATTAGCAGATAAGTA
CGATCTTTCTCGTCGGCAGTTAGGCTACACCTTTCAAAAAATAAATAATTGGTTAACAGAAAGTCAGTTACCAGAAATTG
AGCGAACACGTAAGGGTCAATTTATTATTGATCAGTCCATACTTACTGCAACAGTGACATCAAAGGTTTCACCTATATCA
AACCGTGAAGTGATTTTATCCGAAGTGGACCGAGTGAAATTCTTATTAATTATGATCCTTGGTGGTAAAGAACCATTATC
ATTAGCACATTTTACATCGCAGTTATCCATAAGTAAAAATACGGTTCTAAATGATATGAAACAAGCTCAGAATCATTTAA
ATGCTTATCAATTAGAGATTCAATATTCACGTAAAGATGGATACCAAATTGAAGGCGATGAATTTCAGGCTAGAAAAGTA
ATGATTTGGTTAGCGAATGACATTATTCTTCATTCCGATGAAAAGGAAAAGTTACATGAAGCATTGCAACTTGAAGGTAG
TTTACTTGAACAATTCCACCGTCGTCTAGAACGAGTGGAAAATAAGCTCCATATCGAATTTACAGATGAAAAATTGATGA
CGATGCCAACCATTTTTTCTTTGATATTGAGACGGATTCGAAAAGGATTCCAGATTCAACCATTATCCATTCGATATGAT
GAATTATCCAATACAAAAGAATATCAAGCTACAGAAGAGATTTTGTATGATAAGAGTCTTCCAGTTCCAGAGAAATTATT
TATTACTTTAAACTTATTAACAGGTAGTGTACATCGTAACCAACTTTTAATAGAAGACTCTATTCCAGATCTAGTACCAG
CAATTGATAAAATGGTTCGGTTATTTGAGAAGAATGCCTGTATTATCTTTCAGGATCGTGAGCAGCTAATCGATAAACTA
TTACAGCATCTTACCCCAGCTTATTATCGAATTAAGTACAAATTAACCGATGCAATAGTATTTGAGAGCACGTATAATGA
AGAATTTGAACAAATTCGACATTTGATTAAACGGGCATTAGAGCCAATTAGTGAAGTAATGGAAAGTAAGATTCCTGAAA
ATGAAATTACCTACATTGTTATGCTTGTCAGTGGCTGGATGCATATGCAAGGGGAAAGTATGACAGAAAAGGTAAAGGCA
ATTGTTGTATGCCCACAAGGAGTTTCTGTATCGAGGTTAATGTTTCATCAGTTAAAAGAACTTTTCCCAGAGTTTGTATT
CTTAGATTCATTATCAGTCCGAGAATTTCTAACGTATGGGCTAGAGTACGATGTTGTTTTTTCACCAATTGCTTTAGAGA
CGGAGAAGAATCTGTTTATTTCAAAAACAATGCTACGTCCAGAAGATAAACAACGATTACGTAAGCAAGTGATGCTAGAA
GTGTATGACTATATTCCAAACGAAATTAATGTGGATGACATATTAAAAACAGTTGGACAGTATGCGGATGTAAATGATGA
AAAGCAATTAAGAAAAGAGTTATATGCATACATCCATCGAGATGAAAACGCAACAATAACAAGACAATTAAGTACTTCTA
TGGAGTTAGATTTACATGAATTTATAATCCCGAAACATATTACGCTCAGAGAGTCAGTTCCATCTTTTGAAGATGCAATT
CGACTTTGTGCTGAACCACTACTGAAATCAGGGCATATTGAGCAACATTACGTAGAAGCTGCGATCAGACATTCTCAAGA
AGATTCCTATATTGCTATCGGACCGCACGTAGCAATTCCTCATGCTGCCCCAGAAGATGGGGTACGACAGGTAGGAATGA
GCTTACTTCGGATCAAAAATGGTGTGACATATGGAGAAGAGGGTCATCAAATTAAACTAATGATTATGATTGCAGCTGTT
GATAAACAACAACATATACATGCTTTAATGCAATTAATGAAAGTTGCTTCATCTGAGACAATTTTACCTAAACTCGTTCA
GGCTAATTCAAAGCAATATATTCATCAATTAATTGAAGCTTATGTTAGGGGCAGCTAA

Upstream 100 bases:

>100_bases
CAATATTGTACAATGATGATTCTTATATTTGTGATGAAAACGTATACATTATTGAAAAATCAACTGTTATGATAAAAAAC
AAAGGAGGTCAACAACCGTG

Downstream 100 bases:

>100_bases
TTACAGCAAAAGAAAGTGAAGGTAGGGGTGTGACATAATGAGTGAATTACATTTTGAAGAAGATGTTATTTTACTAGATT
TAGATGTAGAAAAAAATGAA

Product: hypothetical protein

Products: NA

Alternate protein names: Putative phosphotransferase enzyme IIB component; Putative PTS system EIIB component; Putative phosphotransferase enzyme IIA component; Putative PTS system EIIA component [H]

Number of amino acids: Translated: 685; Mature: 684

Protein sequence:

>685_residues
MGEREEQILNELIKDTSITSSKLADKYDLSRRQLGYTFQKINNWLTESQLPEIERTRKGQFIIDQSILTATVTSKVSPIS
NREVILSEVDRVKFLLIMILGGKEPLSLAHFTSQLSISKNTVLNDMKQAQNHLNAYQLEIQYSRKDGYQIEGDEFQARKV
MIWLANDIILHSDEKEKLHEALQLEGSLLEQFHRRLERVENKLHIEFTDEKLMTMPTIFSLILRRIRKGFQIQPLSIRYD
ELSNTKEYQATEEILYDKSLPVPEKLFITLNLLTGSVHRNQLLIEDSIPDLVPAIDKMVRLFEKNACIIFQDREQLIDKL
LQHLTPAYYRIKYKLTDAIVFESTYNEEFEQIRHLIKRALEPISEVMESKIPENEITYIVMLVSGWMHMQGESMTEKVKA
IVVCPQGVSVSRLMFHQLKELFPEFVFLDSLSVREFLTYGLEYDVVFSPIALETEKNLFISKTMLRPEDKQRLRKQVMLE
VYDYIPNEINVDDILKTVGQYADVNDEKQLRKELYAYIHRDENATITRQLSTSMELDLHEFIIPKHITLRESVPSFEDAI
RLCAEPLLKSGHIEQHYVEAAIRHSQEDSYIAIGPHVAIPHAAPEDGVRQVGMSLLRIKNGVTYGEEGHQIKLMIMIAAV
DKQQHIHALMQLMKVASSETILPKLVQANSKQYIHQLIEAYVRGS

Sequences:

>Translated_685_residues
MGEREEQILNELIKDTSITSSKLADKYDLSRRQLGYTFQKINNWLTESQLPEIERTRKGQFIIDQSILTATVTSKVSPIS
NREVILSEVDRVKFLLIMILGGKEPLSLAHFTSQLSISKNTVLNDMKQAQNHLNAYQLEIQYSRKDGYQIEGDEFQARKV
MIWLANDIILHSDEKEKLHEALQLEGSLLEQFHRRLERVENKLHIEFTDEKLMTMPTIFSLILRRIRKGFQIQPLSIRYD
ELSNTKEYQATEEILYDKSLPVPEKLFITLNLLTGSVHRNQLLIEDSIPDLVPAIDKMVRLFEKNACIIFQDREQLIDKL
LQHLTPAYYRIKYKLTDAIVFESTYNEEFEQIRHLIKRALEPISEVMESKIPENEITYIVMLVSGWMHMQGESMTEKVKA
IVVCPQGVSVSRLMFHQLKELFPEFVFLDSLSVREFLTYGLEYDVVFSPIALETEKNLFISKTMLRPEDKQRLRKQVMLE
VYDYIPNEINVDDILKTVGQYADVNDEKQLRKELYAYIHRDENATITRQLSTSMELDLHEFIIPKHITLRESVPSFEDAI
RLCAEPLLKSGHIEQHYVEAAIRHSQEDSYIAIGPHVAIPHAAPEDGVRQVGMSLLRIKNGVTYGEEGHQIKLMIMIAAV
DKQQHIHALMQLMKVASSETILPKLVQANSKQYIHQLIEAYVRGS
>Mature_684_residues
GEREEQILNELIKDTSITSSKLADKYDLSRRQLGYTFQKINNWLTESQLPEIERTRKGQFIIDQSILTATVTSKVSPISN
REVILSEVDRVKFLLIMILGGKEPLSLAHFTSQLSISKNTVLNDMKQAQNHLNAYQLEIQYSRKDGYQIEGDEFQARKVM
IWLANDIILHSDEKEKLHEALQLEGSLLEQFHRRLERVENKLHIEFTDEKLMTMPTIFSLILRRIRKGFQIQPLSIRYDE
LSNTKEYQATEEILYDKSLPVPEKLFITLNLLTGSVHRNQLLIEDSIPDLVPAIDKMVRLFEKNACIIFQDREQLIDKLL
QHLTPAYYRIKYKLTDAIVFESTYNEEFEQIRHLIKRALEPISEVMESKIPENEITYIVMLVSGWMHMQGESMTEKVKAI
VVCPQGVSVSRLMFHQLKELFPEFVFLDSLSVREFLTYGLEYDVVFSPIALETEKNLFISKTMLRPEDKQRLRKQVMLEV
YDYIPNEINVDDILKTVGQYADVNDEKQLRKELYAYIHRDENATITRQLSTSMELDLHEFIIPKHITLRESVPSFEDAIR
LCAEPLLKSGHIEQHYVEAAIRHSQEDSYIAIGPHVAIPHAAPEDGVRQVGMSLLRIKNGVTYGEEGHQIKLMIMIAAVD
KQQHIHALMQLMKVASSETILPKLVQANSKQYIHQLIEAYVRGS

Specific function: May regulate the expression of the mannose operon [H]

COG id: COG3711

COG function: function code K; Transcriptional antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1789302, Length=114, Percent_Identity=32.4561403508772, Blast_Score=63, Evalue=7e-11,
Organism=Escherichia coli, GI2367359, Length=138, Percent_Identity=26.0869565217391, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013196
- InterPro:   IPR007737
- InterPro:   IPR011608
- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08279 HTH_11; PF05043 Mga; PF00874 PRD; PF00359 PTS_EIIA_2 [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 79452; Mature: 79321

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS00372 PTS_EIIA_TYPE_2_HIS ; PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEREEQILNELIKDTSITSSKLADKYDLSRRQLGYTFQKINNWLTESQLPEIERTRKGQ
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCC
FIIDQSILTATVTSKVSPISNREVILSEVDRVKFLLIMILGGKEPLSLAHFTSQLSISKN
EEEECHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCHH
TVLNDMKQAQNHLNAYQLEIQYSRKDGYQIEGDEFQARKVMIWLANDIILHSDEKEKLHE
HHHHHHHHHHHCCCEEEEEEEEECCCCCEECCCCCCCEEEEEEEECCEEEECCHHHHHHH
ALQLEGSLLEQFHRRLERVENKLHIEFTDEKLMTMPTIFSLILRRIRKGFQIQPLSIRYD
HHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEHH
ELSNTKEYQATEEILYDKSLPVPEKLFITLNLLTGSVHRNQLLIEDSIPDLVPAIDKMVR
HCCCCHHHHHHHHHHHCCCCCCCCEEEEEEEEHCCCCCCCEEEEECCCCHHHHHHHHHHH
LFEKNACIIFQDREQLIDKLLQHLTPAYYRIKYKLTDAIVFESTYNEEFEQIRHLIKRAL
HHHCCCEEEECCHHHHHHHHHHHCCCHHEEEEEEEEEEEEEECCCHHHHHHHHHHHHHHH
EPISEVMESKIPENEITYIVMLVSGWMHMQGESMTEKVKAIVVCPQGVSVSRLMFHQLKE
HHHHHHHHHCCCCCHHHEEEEEECCHHHCCCCCHHHHCEEEEECCCCCCHHHHHHHHHHH
LFPEFVFLDSLSVREFLTYGLEYDVVFSPIALETEKNLFISKTMLRPEDKQRLRKQVMLE
HHHHHHHHCCCHHHHHHHHCCCEEEEECCEEEECCCCEEEEHHHCCCHHHHHHHHHHHHH
VYDYIPNEINVDDILKTVGQYADVNDEKQLRKELYAYIHRDENATITRQLSTSMELDLHE
HHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEHHHHCCCCCCHHH
FIIPKHITLRESVPSFEDAIRLCAEPLLKSGHIEQHYVEAAIRHSQEDSYIAIGPHVAIP
HHCCCCCCHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEECCCEECC
HAAPEDGVRQVGMSLLRIKNGVTYGEEGHQIKLMIMIAAVDKQQHIHALMQLMKVASSET
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHCCCH
ILPKLVQANSKQYIHQLIEAYVRGS
HHHHHHHCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GEREEQILNELIKDTSITSSKLADKYDLSRRQLGYTFQKINNWLTESQLPEIERTRKGQ
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCC
FIIDQSILTATVTSKVSPISNREVILSEVDRVKFLLIMILGGKEPLSLAHFTSQLSISKN
EEEECHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCHH
TVLNDMKQAQNHLNAYQLEIQYSRKDGYQIEGDEFQARKVMIWLANDIILHSDEKEKLHE
HHHHHHHHHHHCCCEEEEEEEEECCCCCEECCCCCCCEEEEEEEECCEEEECCHHHHHHH
ALQLEGSLLEQFHRRLERVENKLHIEFTDEKLMTMPTIFSLILRRIRKGFQIQPLSIRYD
HHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEHH
ELSNTKEYQATEEILYDKSLPVPEKLFITLNLLTGSVHRNQLLIEDSIPDLVPAIDKMVR
HCCCCHHHHHHHHHHHCCCCCCCCEEEEEEEEHCCCCCCCEEEEECCCCHHHHHHHHHHH
LFEKNACIIFQDREQLIDKLLQHLTPAYYRIKYKLTDAIVFESTYNEEFEQIRHLIKRAL
HHHCCCEEEECCHHHHHHHHHHHCCCHHEEEEEEEEEEEEEECCCHHHHHHHHHHHHHHH
EPISEVMESKIPENEITYIVMLVSGWMHMQGESMTEKVKAIVVCPQGVSVSRLMFHQLKE
HHHHHHHHHCCCCCHHHEEEEEECCHHHCCCCCHHHHCEEEEECCCCCCHHHHHHHHHHH
LFPEFVFLDSLSVREFLTYGLEYDVVFSPIALETEKNLFISKTMLRPEDKQRLRKQVMLE
HHHHHHHHCCCHHHHHHHHCCCEEEEECCEEEECCCCEEEEHHHCCCHHHHHHHHHHHHH
VYDYIPNEINVDDILKTVGQYADVNDEKQLRKELYAYIHRDENATITRQLSTSMELDLHE
HHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEHHHHCCCCCCHHH
FIIPKHITLRESVPSFEDAIRLCAEPLLKSGHIEQHYVEAAIRHSQEDSYIAIGPHVAIP
HHCCCCCCHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEECCCEECC
HAAPEDGVRQVGMSLLRIKNGVTYGEEGHQIKLMIMIAAVDKQQHIHALMQLMKVASSET
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHCCCH
ILPKLVQANSKQYIHQLIEAYVRGS
HHHHHHHCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]