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The map label for this gene is hxlB [H]

Identifier: 23100159

GI number: 23100159

Start: 2773988

End: 2774545

Strand: Reverse

Name: hxlB [H]

Synonym: OB2704

Alternate gene names: 23100159

Gene position: 2774545-2773988 (Counterclockwise)

Preceding gene: 23100160

Following gene: 23100158

Centisome position: 76.42

GC content: 37.99

Gene sequence:

>558_bases
ATGAAACAAAAAGTAAATACTATCGCTAAAGAAATTCAGGAAGTACTTGGACAAGTTAATGAAGCTGAACTAATTGAATT
AGCGGAAGGTATCCAACAAGCATCCCGCGTATTTATTGCGGGTACCGGACGCTCTGGGTTAGTTGGAAAGATGTTTGGTA
TGCGCCTTATGCATAGTGGCTATCAGATTTATATTGTTGGAGAAACAAATACACCTAGTCTTGAATCAAATGATTTACTG
ATATTAATTTCTGGATCAGGGGGAACATCTTCATTATTAAACTATGCAAAAAAAGCAAAGGAAATTGATGCGAAAGTAGC
TTTAGTAACCACAAACAAAGAATCGGCAATTGGCTCTCAAAGTACGTATATCGTACGTGTCCCTGCTGCCACTAAAAAGC
GTTTGCCGCAGGAACCAGAGACAATTCAACCACTGGGTAGTCAATTTGATCAATCGGCGCATCTATTATTAGATGCCATC
GTGGTGTATTTATTAGATACGTATCCAGCTAACCGTACTGTGGAAAGTCTAAACCAAAAACATACTAATTTAGAATAA

Upstream 100 bases:

>100_bases
ATCAAAAATCCACAAGATAGAAGTACAATGGAAACCTTCCGTTTCGAACCAATGGTGAATCGGAGAAAATCGTGTTGAAC
AGAAAGGAAAGATAAGGATG

Downstream 100 bases:

>100_bases
GGTGGGATTATTTATGTCAGTAATAGAAGGTATTCAAGAAGAAAAAGTAGTAGCAGTTATCCGAAAAGCAAATTCGGATA
ATATTGTACCTATTTTGGAA

Product: hypothetical protein

Products: NA

Alternate protein names: 6-phospho-3-hexuloisomerase; PHI [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MKQKVNTIAKEIQEVLGQVNEAELIELAEGIQQASRVFIAGTGRSGLVGKMFGMRLMHSGYQIYIVGETNTPSLESNDLL
ILISGSGGTSSLLNYAKKAKEIDAKVALVTTNKESAIGSQSTYIVRVPAATKKRLPQEPETIQPLGSQFDQSAHLLLDAI
VVYLLDTYPANRTVESLNQKHTNLE

Sequences:

>Translated_185_residues
MKQKVNTIAKEIQEVLGQVNEAELIELAEGIQQASRVFIAGTGRSGLVGKMFGMRLMHSGYQIYIVGETNTPSLESNDLL
ILISGSGGTSSLLNYAKKAKEIDAKVALVTTNKESAIGSQSTYIVRVPAATKKRLPQEPETIQPLGSQFDQSAHLLLDAI
VVYLLDTYPANRTVESLNQKHTNLE
>Mature_185_residues
MKQKVNTIAKEIQEVLGQVNEAELIELAEGIQQASRVFIAGTGRSGLVGKMFGMRLMHSGYQIYIVGETNTPSLESNDLL
ILISGSGGTSSLLNYAKKAKEIDAKVALVTTNKESAIGSQSTYIVRVPAATKKRLPQEPETIQPLGSQFDQSAHLLLDAI
VVYLLDTYPANRTVESLNQKHTNLE

Specific function: Catalyzes the isomerization between 3-hexulose 6- phosphate and fructose 6-phosphate. Together with hxlA, may act as a formaldehyde detoxification system [H]

COG id: COG0794

COG function: function code M; Predicted sugar phosphate isomerase involved in capsule formation

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017552
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.27 [H]

Molecular weight: Translated: 20115; Mature: 20115

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQKVNTIAKEIQEVLGQVNEAELIELAEGIQQASRVFIAGTGRSGLVGKMFGMRLMHSG
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHHHCC
YQIYIVGETNTPSLESNDLLILISGSGGTSSLLNYAKKAKEIDAKVALVTTNKESAIGSQ
CEEEEEECCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCEEEEEECCCHHHCCCC
STYIVRVPAATKKRLPQEPETIQPLGSQFDQSAHLLLDAIVVYLLDTYPANRTVESLNQK
CEEEEECCCHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
HTNLE
CCCCC
>Mature Secondary Structure
MKQKVNTIAKEIQEVLGQVNEAELIELAEGIQQASRVFIAGTGRSGLVGKMFGMRLMHSG
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHHHCC
YQIYIVGETNTPSLESNDLLILISGSGGTSSLLNYAKKAKEIDAKVALVTTNKESAIGSQ
CEEEEEECCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCEEEEEECCCHHHCCCC
STYIVRVPAATKKRLPQEPETIQPLGSQFDQSAHLLLDAIVVYLLDTYPANRTVESLNQK
CEEEEECCCHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
HTNLE
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704255; 8969502; 9384377; 7921238 [H]