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The map label for this gene is 23100053

Identifier: 23100053

GI number: 23100053

Start: 2657681

End: 2658895

Strand: Direct

Name: 23100053

Synonym: OB2598

Alternate gene names: NA

Gene position: 2657681-2658895 (Clockwise)

Preceding gene: 23100050

Following gene: 23100054

Centisome position: 73.2

GC content: 37.7

Gene sequence:

>1215_bases
ATGAAAAGCAAAATTTTTGGCGGATTAGCATTAGCTATTTTCCTAGTTACTTCACCACTGGCAACAGATGCTGCAATGGA
CAGGAACAACGGAATTGACATGGAAACAAACCCAAGTATTTCAGACTCTTATGACAAACAAACTCCATATGTTGAAGGAG
AGGTTCTTGTAAAGTTCAAAGAAGACATGTCCATGAATATGCAACAAGAAGTATTAAGTGATATTAATGCCGAAATTCTT
GTTGATGAAAATGTAGTAGACTCTCCTTTTAGTGTTTTAAAAGTAAAGGACGTAGAACAAGTAGTACAAACGTTAAGTAA
TAATTCTCAAATTGAATATGTCGAACCAAATTATATCTTGAATGCAACTTACACACCAAATGATCCTTTCTTTGATATTA
GTTACCAATATGGATTATTCACATCAGAAACAACCTCTGCTTGGGATGTAACAACCGGTAATTCTAATCAATTGGTTGCC
GTTCTGGATACTGGTGTTGATTACAACCATGAAGATTTAGATGATAAAACAATTCTTGGATATAATTTTGTTAATAATAA
TTACAACCCGATCGACCGTAATGGACATGGCACTCACGTAGCTGGAACTGCCGCTGCAGAAACGAATAATGGATTAGGGA
TAGCAGGTGTGGCTCCTGACACCTCCGTCTTAGCAGTCCAAGTTCTCGATAGTAGTGGTAATGGAAGTTTAGCAAATATC
GTTGATGGAATTATCTACGCAGCAGATTATGGTGCAGAAGTTATTAATCTTTCCTTAGGCTGTAATTGTGATACCCAAGC
AATGGAAGATGCTGTCGACTATGCTTGGGACAATGGTTCTGTAGTTGTAGCTGCAGCAGGAAATAGTAGTACCTCTACAA
CATTTGAACCCGCATCATATGACAATGCTATAGCAGTTGGAGCAGTTGACGAAAATAATAATATAGCTAGTTTTTCCAAC
TACGGAAGATGGGTAGATGTAACTGCACCAGGTGTTGAAATTGCAGGAACATATCCATCAAATAGATATGTCTATTTATC
AGGTACTTCAATGGCTTCTCCGCATGTTGCTGGTTTAGCAGCGTTACTTGCATCACAAGGTAAGGATAACAGTGAGATTC
GTAGTTCCATCGAAAATACAGCAACACCAATTAGCGGAACAGGTACTTACTTCCAACACGGATTAATCAATTCATTTGAT
GCAGTAAACTATTAA

Upstream 100 bases:

>100_bases
ATTTTCTGTAATTCTCATCCTTTTTCCCAACCCCTAAATAGCAGGACTCTTCGAAATTTCACAGAATATGTATAAGCATA
TCTTAAAAGGAGGAATTATG

Downstream 100 bases:

>100_bases
TCTTTGAAAACGTTCCCCCTTCCCCTTCACTTTTTTTGAAGGGGAATTTTTTATGTAGAAGTATATTTCGTTATTTCCAC
AGTTTTATAAACATGAATAA

Product: serine proteinase

Products: NA

Alternate protein names: Ak.1 protease [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MKSKIFGGLALAIFLVTSPLATDAAMDRNNGIDMETNPSISDSYDKQTPYVEGEVLVKFKEDMSMNMQQEVLSDINAEIL
VDENVVDSPFSVLKVKDVEQVVQTLSNNSQIEYVEPNYILNATYTPNDPFFDISYQYGLFTSETTSAWDVTTGNSNQLVA
VLDTGVDYNHEDLDDKTILGYNFVNNNYNPIDRNGHGTHVAGTAAAETNNGLGIAGVAPDTSVLAVQVLDSSGNGSLANI
VDGIIYAADYGAEVINLSLGCNCDTQAMEDAVDYAWDNGSVVVAAAGNSSTSTTFEPASYDNAIAVGAVDENNNIASFSN
YGRWVDVTAPGVEIAGTYPSNRYVYLSGTSMASPHVAGLAALLASQGKDNSEIRSSIENTATPISGTGTYFQHGLINSFD
AVNY

Sequences:

>Translated_404_residues
MKSKIFGGLALAIFLVTSPLATDAAMDRNNGIDMETNPSISDSYDKQTPYVEGEVLVKFKEDMSMNMQQEVLSDINAEIL
VDENVVDSPFSVLKVKDVEQVVQTLSNNSQIEYVEPNYILNATYTPNDPFFDISYQYGLFTSETTSAWDVTTGNSNQLVA
VLDTGVDYNHEDLDDKTILGYNFVNNNYNPIDRNGHGTHVAGTAAAETNNGLGIAGVAPDTSVLAVQVLDSSGNGSLANI
VDGIIYAADYGAEVINLSLGCNCDTQAMEDAVDYAWDNGSVVVAAAGNSSTSTTFEPASYDNAIAVGAVDENNNIASFSN
YGRWVDVTAPGVEIAGTYPSNRYVYLSGTSMASPHVAGLAALLASQGKDNSEIRSSIENTATPISGTGTYFQHGLINSFD
AVNY
>Mature_404_residues
MKSKIFGGLALAIFLVTSPLATDAAMDRNNGIDMETNPSISDSYDKQTPYVEGEVLVKFKEDMSMNMQQEVLSDINAEIL
VDENVVDSPFSVLKVKDVEQVVQTLSNNSQIEYVEPNYILNATYTPNDPFFDISYQYGLFTSETTSAWDVTTGNSNQLVA
VLDTGVDYNHEDLDDKTILGYNFVNNNYNPIDRNGHGTHVAGTAAAETNNGLGIAGVAPDTSVLAVQVLDSSGNGSLANI
VDGIIYAADYGAEVINLSLGCNCDTQAMEDAVDYAWDNGSVVVAAAGNSSTSTTFEPASYDNAIAVGAVDENNNIASFSN
YGRWVDVTAPGVEIAGTYPSNRYVYLSGTSMASPHVAGLAALLASQGKDNSEIRSSIENTATPISGTGTYFQHGLINSFD
AVNY

Specific function: Unknown

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI4506775, Length=278, Percent_Identity=29.136690647482, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320775, Length=315, Percent_Identity=34.2857142857143, Blast_Score=132, Evalue=8e-32,
Organism=Saccharomyces cerevisiae, GI6324576, Length=297, Percent_Identity=35.3535353535354, Blast_Score=126, Evalue=7e-30,
Organism=Saccharomyces cerevisiae, GI6319893, Length=365, Percent_Identity=29.5890410958904, Blast_Score=122, Evalue=1e-28,
Organism=Drosophila melanogaster, GI45550681, Length=237, Percent_Identity=29.1139240506329, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR009020 [H]

Pfam domain/function: PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 43058; Mature: 43058

Theoretical pI: Translated: 3.75; Mature: 3.75

Prosite motif: PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSKIFGGLALAIFLVTSPLATDAAMDRNNGIDMETNPSISDSYDKQTPYVEGEVLVKFK
CCCCHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEE
EDMSMNMQQEVLSDINAEILVDENVVDSPFSVLKVKDVEQVVQTLSNNSQIEYVEPNYIL
CCCCCCHHHHHHHCCCCEEEEECCCCCCCHHEEEEHHHHHHHHHHCCCCEEEEECCCEEE
NATYTPNDPFFDISYQYGLFTSETTSAWDVTTGNSNQLVAVLDTGVDYNHEDLDDKTILG
EEEECCCCCEEEEEEEECEEECCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCEEEE
YNFVNNNYNPIDRNGHGTHVAGTAAAETNNGLGIAGVAPDTSVLAVQVLDSSGNGSLANI
EEEECCCCCCCCCCCCCCEEEEEEECCCCCCEEEEECCCCCCEEEEEEEECCCCCCHHHH
VDGIIYAADYGAEVINLSLGCNCDTQAMEDAVDYAWDNGSVVVAAAGNSSTSTTFEPASY
HHHHEEEECCCCEEEEEEECCCCCHHHHHHHHHHEECCCCEEEEECCCCCCCCEECCCCC
DNAIAVGAVDENNNIASFSNYGRWVDVTAPGVEIAGTYPSNRYVYLSGTSMASPHVAGLA
CCEEEEEEECCCCCEEECCCCCCEEEEECCCEEEEECCCCCCEEEEECCCCCCCHHHHHH
ALLASQGKDNSEIRSSIENTATPISGTGTYFQHGLINSFDAVNY
HHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKSKIFGGLALAIFLVTSPLATDAAMDRNNGIDMETNPSISDSYDKQTPYVEGEVLVKFK
CCCCHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEE
EDMSMNMQQEVLSDINAEILVDENVVDSPFSVLKVKDVEQVVQTLSNNSQIEYVEPNYIL
CCCCCCHHHHHHHCCCCEEEEECCCCCCCHHEEEEHHHHHHHHHHCCCCEEEEECCCEEE
NATYTPNDPFFDISYQYGLFTSETTSAWDVTTGNSNQLVAVLDTGVDYNHEDLDDKTILG
EEEECCCCCEEEEEEEECEEECCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCEEEE
YNFVNNNYNPIDRNGHGTHVAGTAAAETNNGLGIAGVAPDTSVLAVQVLDSSGNGSLANI
EEEECCCCCCCCCCCCCCEEEEEEECCCCCCEEEEECCCCCCEEEEEEEECCCCCCHHHH
VDGIIYAADYGAEVINLSLGCNCDTQAMEDAVDYAWDNGSVVVAAAGNSSTSTTFEPASY
HHHHEEEECCCCEEEEEEECCCCCHHHHHHHHHHEECCCCEEEEECCCCCCCCEECCCCC
DNAIAVGAVDENNNIASFSNYGRWVDVTAPGVEIAGTYPSNRYVYLSGTSMASPHVAGLA
CCEEEEEEECCCCCEEECCCCCCEEEEECCCEEEEECCCCCCEEEEECCCCCCCHHHHHH
ALLASQGKDNSEIRSSIENTATPISGTGTYFQHGLINSFDAVNY
HHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7993087; 10588904 [H]