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The map label for this gene is licA [H]

Identifier: 23099730

GI number: 23099730

Start: 2318680

End: 2319015

Strand: Direct

Name: licA [H]

Synonym: OB2275

Alternate gene names: 23099730

Gene position: 2318680-2319015 (Clockwise)

Preceding gene: 23099729

Following gene: 23099731

Centisome position: 63.87

GC content: 33.33

Gene sequence:

>336_bases
ATGGCCACACAACAGGAAGAATTACAAATGCTTTCATTTCAAATTATATTACATGCTGGAAATGCCAGATCAGAAGCAAT
GGAAGCATTACAGCTTGCTAGAAAAGGAGAATTTAAAGAAGCAGAATTAAAATTAGAGGCTGCTGATAAAGAATTTACCG
AAGCGCATCATATACAAACTTCCTTATTACAGGATGAAGCTAATGGAAACAGCCCTGACTTTTCTATAATTCTTATCCAT
GCTCAAGATCATTTAATGAATGCTCTTACAGTTAAAGATTTAGCAATCGAAATGATTGCAATGCAAAAACAAATAAAAAA
ATTGGAGGAGAGATAA

Upstream 100 bases:

>100_bases
TATTACAGCTCATTAACTTAACCATAGCCGTACTATTATATATTCCATTTATTATGGCTGGTGTTCGTTCAATGAAAGAA
AAGATCGGAGGGCAAAAATA

Downstream 100 bases:

>100_bases
CATGAAAATTCGTCTCGTATGCTCTGCCGGAATGTCTACGTCCATGCTTGTGAAAAAAATGGAAATTGCAGCAACAGAGA
AAGAAATAGAAGCAGAAATT

Product: PTS system cellobiose-specific enzyme II A component

Products: protein histidine; sugar phosphate

Alternate protein names: EIIA-Lic; EIII-Lic; PTS system lichenan-specific EIIA component [H]

Number of amino acids: Translated: 111; Mature: 110

Protein sequence:

>111_residues
MATQQEELQMLSFQIILHAGNARSEAMEALQLARKGEFKEAELKLEAADKEFTEAHHIQTSLLQDEANGNSPDFSIILIH
AQDHLMNALTVKDLAIEMIAMQKQIKKLEER

Sequences:

>Translated_111_residues
MATQQEELQMLSFQIILHAGNARSEAMEALQLARKGEFKEAELKLEAADKEFTEAHHIQTSLLQDEANGNSPDFSIILIH
AQDHLMNALTVKDLAIEMIAMQKQIKKLEER
>Mature_110_residues
ATQQEELQMLSFQIILHAGNARSEAMEALQLARKGEFKEAELKLEAADKEFTEAHHIQTSLLQDEANGNSPDFSIILIHA
QDHLMNALTVKDLAIEMIAMQKQIKKLEER

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG1447

COG function: function code G; Phosphotransferase system cellobiose-specific component IIA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIA type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788031, Length=104, Percent_Identity=34.6153846153846, Blast_Score=72, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003188 [H]

Pfam domain/function: PF02255 PTS_IIA [H]

EC number: 2.7.1.69

Molecular weight: Translated: 12571; Mature: 12439

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS51095 PTS_EIIA_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATQQEELQMLSFQIILHAGNARSEAMEALQLARKGEFKEAELKLEAADKEFTEAHHIQT
CCCCHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCCCHHHEEEECCCCHHHHHHHHHH
SLLQDEANGNSPDFSIILIHAQDHLMNALTVKDLAIEMIAMQKQIKKLEER
HHHHHCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATQQEELQMLSFQIILHAGNARSEAMEALQLARKGEFKEAELKLEAADKEFTEAHHIQT
CCCHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCCCHHHEEEECCCCHHHHHHHHHH
SLLQDEANGNSPDFSIILIHAQDHLMNALTVKDLAIEMIAMQKQIKKLEER
HHHHHCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377 [H]