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The map label for this gene is licC [H]

Identifier: 23099729

GI number: 23099729

Start: 2317388

End: 2318680

Strand: Direct

Name: licC [H]

Synonym: OB2274

Alternate gene names: 23099729

Gene position: 2317388-2318680 (Clockwise)

Preceding gene: 23099728

Following gene: 23099730

Centisome position: 63.83

GC content: 35.81

Gene sequence:

>1293_bases
ATGAATAACAAATTTATGCAGAAATTCATTGAAATAGCTGGTCGTATTGGTTCACAAAGACATTTAGTTGCCATACGTGA
TGGTTTCGTTGCTATTATGCCTTTAATTATTATTGGATCTTTAGCTGTATTAATCAATAGTTTCCCAAACTTCGGGAATT
TTAGTCTAGTAGAAATGCTAAATGGTATATTTGGTGAAGGTAAATGGCAAGTAGTTGGAGGAAGCATATGGAATGGTACT
TTCGCTGTATTAGGACTACTCATATCATTTTCTATCGCATATAATTTAGCTAAGTCCTATGAAATAGACGGTTTGTCATC
AGGTCTAATTTCTGCTGCAGCTTTTATTATGCTCGTTCCGACGACAGGCGATGGAGGATTGAATATTGCTTGGCTAGGAG
CACAAGGATTATTCGTCGCTATTATTCTATCTATATTAGCAACCGAATTCTTCCGTTTTCTCATTAAGTCGAATATTACC
ATTAAGATGCCAGAAGGTGTCCCCGAAGGTGTTTCTAGATCCTTTTCTGCTTTAATACCAGCAATTATTATTCTTTTCCT
TGTTGGCTTATTCCATGCATTAGTTAGTGTTTTCTCTGGAATTAGTATATTTGAAGTCATATTCAATGTAATACAAGAGC
CTCTACAAGGACTTGGGAATACCTTACCTGCAGCCATCGTAGTTGCCTTCTTAAATCATTTATTGTGGTTCTTTGGGCTT
CACGGTACCAATATTATTGGATCAGTAATCGAACCGGTATATCTACCGCTGATTGAACGTAATGCAGATTTATTCCAAAA
TGGTATGTCCGCTTTTGATGTGCCAAATGTAGTAACAAAACCATTTTTAGATACATTTGTCTTTATGGGTGGATCTGGAA
CAACAATTGCTTTGCTAATTGCCATATTTATTGTTATCCGACATGAAAAAAACCATCCATATCGAGAGGTAGCAAAGTTA
TCAGCACCAGCTGGGTTGTTTAATATTAATGAACCAGTAATTTTTGGTTTGCCAATTGTATTAAATCCAATCTTTTTAAT
ACCTTTTATTCTTGTACCTGTTACTTTAACCATAACTTCTTATTTTGCTTTGTCTTTAGGTCTTGTACCAAAAACCGTCG
CCATACTTCCTTGGACGACTCCACCTATTTTAAGTGGATACCTTGTCACTGGAGGAAGTGTACGTGGAATCATATTACAG
CTCATTAACTTAACCATAGCCGTACTATTATATATTCCATTTATTATGGCTGGTGTTCGTTCAATGAAAGAAAAGATCGG
AGGGCAAAAATAA

Upstream 100 bases:

>100_bases
ATTAATTCAAGACGAAAAAAAAGCAAAAGTGTTACTTGATGAACTTTTAGAAGCTCACAAAGCTTACCTACCACAATTTA
AACAATAGGAGGAAATAAGC

Downstream 100 bases:

>100_bases
TGGCCACACAACAGGAAGAATTACAAATGCTTTCATTTCAAATTATATTACATGCTGGAAATGCCAGATCAGAAGCAATG
GAAGCATTACAGCTTGCTAG

Product: PTS system cellobiose-specific enzyme II C component

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: EIIC-Lic; PTS system lichenan-specific EIIC component [H]

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MNNKFMQKFIEIAGRIGSQRHLVAIRDGFVAIMPLIIIGSLAVLINSFPNFGNFSLVEMLNGIFGEGKWQVVGGSIWNGT
FAVLGLLISFSIAYNLAKSYEIDGLSSGLISAAAFIMLVPTTGDGGLNIAWLGAQGLFVAIILSILATEFFRFLIKSNIT
IKMPEGVPEGVSRSFSALIPAIIILFLVGLFHALVSVFSGISIFEVIFNVIQEPLQGLGNTLPAAIVVAFLNHLLWFFGL
HGTNIIGSVIEPVYLPLIERNADLFQNGMSAFDVPNVVTKPFLDTFVFMGGSGTTIALLIAIFIVIRHEKNHPYREVAKL
SAPAGLFNINEPVIFGLPIVLNPIFLIPFILVPVTLTITSYFALSLGLVPKTVAILPWTTPPILSGYLVTGGSVRGIILQ
LINLTIAVLLYIPFIMAGVRSMKEKIGGQK

Sequences:

>Translated_430_residues
MNNKFMQKFIEIAGRIGSQRHLVAIRDGFVAIMPLIIIGSLAVLINSFPNFGNFSLVEMLNGIFGEGKWQVVGGSIWNGT
FAVLGLLISFSIAYNLAKSYEIDGLSSGLISAAAFIMLVPTTGDGGLNIAWLGAQGLFVAIILSILATEFFRFLIKSNIT
IKMPEGVPEGVSRSFSALIPAIIILFLVGLFHALVSVFSGISIFEVIFNVIQEPLQGLGNTLPAAIVVAFLNHLLWFFGL
HGTNIIGSVIEPVYLPLIERNADLFQNGMSAFDVPNVVTKPFLDTFVFMGGSGTTIALLIAIFIVIRHEKNHPYREVAKL
SAPAGLFNINEPVIFGLPIVLNPIFLIPFILVPVTLTITSYFALSLGLVPKTVAILPWTTPPILSGYLVTGGSVRGIILQ
LINLTIAVLLYIPFIMAGVRSMKEKIGGQK
>Mature_430_residues
MNNKFMQKFIEIAGRIGSQRHLVAIRDGFVAIMPLIIIGSLAVLINSFPNFGNFSLVEMLNGIFGEGKWQVVGGSIWNGT
FAVLGLLISFSIAYNLAKSYEIDGLSSGLISAAAFIMLVPTTGDGGLNIAWLGAQGLFVAIILSILATEFFRFLIKSNIT
IKMPEGVPEGVSRSFSALIPAIIILFLVGLFHALVSVFSGISIFEVIFNVIQEPLQGLGNTLPAAIVVAFLNHLLWFFGL
HGTNIIGSVIEPVYLPLIERNADLFQNGMSAFDVPNVVTKPFLDTFVFMGGSGTTIALLIAIFIVIRHEKNHPYREVAKL
SAPAGLFNINEPVIFGLPIVLNPIFLIPFILVPVTLTITSYFALSLGLVPKTVAILPWTTPPILSGYLVTGGSVRGIILQ
LINLTIAVLLYIPFIMAGVRSMKEKIGGQK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=430, Percent_Identity=36.9767441860465, Blast_Score=272, Evalue=4e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: NA

Molecular weight: Translated: 46429; Mature: 46429

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNKFMQKFIEIAGRIGSQRHLVAIRDGFVAIMPLIIIGSLAVLINSFPNFGNFSLVEML
CCHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
NGIFGEGKWQVVGGSIWNGTFAVLGLLISFSIAYNLAKSYEIDGLSSGLISAAAFIMLVP
HHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEEEE
TTGDGGLNIAWLGAQGLFVAIILSILATEFFRFLIKSNITIKMPEGVPEGVSRSFSALIP
ECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHH
AIIILFLVGLFHALVSVFSGISIFEVIFNVIQEPLQGLGNTLPAAIVVAFLNHLLWFFGL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHC
HGTNIIGSVIEPVYLPLIERNADLFQNGMSAFDVPNVVTKPFLDTFVFMGGSGTTIALLI
CCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHH
AIFIVIRHEKNHPYREVAKLSAPAGLFNINEPVIFGLPIVLNPIFLIPFILVPVTLTITS
HHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHH
YFALSLGLVPKTVAILPWTTPPILSGYLVTGGSVRGIILQLINLTIAVLLYIPFIMAGVR
HHHHHHCCCHHHEEEECCCCCHHHCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMKEKIGGQK
HHHHHHCCCC
>Mature Secondary Structure
MNNKFMQKFIEIAGRIGSQRHLVAIRDGFVAIMPLIIIGSLAVLINSFPNFGNFSLVEML
CCHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
NGIFGEGKWQVVGGSIWNGTFAVLGLLISFSIAYNLAKSYEIDGLSSGLISAAAFIMLVP
HHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEEEE
TTGDGGLNIAWLGAQGLFVAIILSILATEFFRFLIKSNITIKMPEGVPEGVSRSFSALIP
ECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHH
AIIILFLVGLFHALVSVFSGISIFEVIFNVIQEPLQGLGNTLPAAIVVAFLNHLLWFFGL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHC
HGTNIIGSVIEPVYLPLIERNADLFQNGMSAFDVPNVVTKPFLDTFVFMGGSGTTIALLI
CCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHH
AIFIVIRHEKNHPYREVAKLSAPAGLFNINEPVIFGLPIVLNPIFLIPFILVPVTLTITS
HHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHH
YFALSLGLVPKTVAILPWTTPPILSGYLVTGGSVRGIILQLINLTIAVLLYIPFIMAGVR
HHHHHHCCCHHHEEEECCCCCHHHCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMKEKIGGQK
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377 [H]