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The map label for this gene is mrpB [H]

Identifier: 23099447

GI number: 23099447

Start: 2018909

End: 2019343

Strand: Direct

Name: mrpB [H]

Synonym: OB1992

Alternate gene names: 23099447

Gene position: 2018909-2019343 (Clockwise)

Preceding gene: 23099446

Following gene: 23099448

Centisome position: 55.61

GC content: 35.4

Gene sequence:

>435_bases
ATGAAACAAGTAAAACCGAATGATGTTATGTTACAAACTTTTGCTCGTATGTTAATTTTTATAATACTTGCGTTCTCCAT
CTACCTACTGTTAGCCGGACATAATAGTCCTGGAGGGGGATTTATAGGTGGTTTGATGACCGCCAGCGCCATTTTGATTC
TTTATTTAGCGTTCGATATGAAAACAATTCGTAAATCCATACCAATTGACTTTGTTAAGATTATTGGAATTGGATTGCTA
TTTGCAAGTTTAACCGGTGTGGTATCCATGCTCTTTGGATTTCCTTATCTAACTCAATTCTTTGACTATTTTCATATCCC
CCTTTTAGGGGAAGTAGAATTGACTACAGCACTACCATTTGATTTAGGTGTATATTTTGTCGTTGTAGGTAGTGCATTAA
CGATAATATTAACAATCGCGGAGGATGATAATTAA

Upstream 100 bases:

>100_bases
TTCGTGGTTTAGATACTATGTTGGAGATTCTTGTTGTAGGGGTAGCTGTTTTATCAATAATCAGCCTTATAAAACTCCGT
TTCAAAGGGAGTGAAGATGT

Downstream 100 bases:

>100_bases
TGGAACTATTGATGTCAATCATCATTGGAATAGTATTCAGTGTCAGTATCTATTTATTCATGTCCAGAAGTCTACTCCGT
GTAGCTGTAGCAAGTGTAAT

Product: putative monovalent cation/H+ antiporter subunit B

Products: NA

Alternate protein names: Mrp complex subunit B; Multiple resistance and pH homeostasis protein B [H]

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MKQVKPNDVMLQTFARMLIFIILAFSIYLLLAGHNSPGGGFIGGLMTASAILILYLAFDMKTIRKSIPIDFVKIIGIGLL
FASLTGVVSMLFGFPYLTQFFDYFHIPLLGEVELTTALPFDLGVYFVVVGSALTIILTIAEDDN

Sequences:

>Translated_144_residues
MKQVKPNDVMLQTFARMLIFIILAFSIYLLLAGHNSPGGGFIGGLMTASAILILYLAFDMKTIRKSIPIDFVKIIGIGLL
FASLTGVVSMLFGFPYLTQFFDYFHIPLLGEVELTTALPFDLGVYFVVVGSALTIILTIAEDDN
>Mature_144_residues
MKQVKPNDVMLQTFARMLIFIILAFSIYLLLAGHNSPGGGFIGGLMTASAILILYLAFDMKTIRKSIPIDFVKIIGIGLL
FASLTGVVSMLFGFPYLTQFFDYFHIPLLGEVELTTALPFDLGVYFVVVGSALTIILTIAEDDN

Specific function: Mnh complex is a Na(+)Li(+)/H(+) antiporter involved in Na(+) and/or Li(+) excretion and Na(+) resistance. Na(+)/H(+) antiport consumes a transmembrane electrical potential, and is thus inferred to be electrogenic. Does not transport K(+), Ca(2+) or Mg(2+

COG id: COG2111

COG function: function code P; Multisubunit Na+/H+ antiporter, MnhB subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007182 [H]

Pfam domain/function: PF04039 MnhB [H]

EC number: NA

Molecular weight: Translated: 15788; Mature: 15788

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQVKPNDVMLQTFARMLIFIILAFSIYLLLAGHNSPGGGFIGGLMTASAILILYLAFDM
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
KTIRKSIPIDFVKIIGIGLLFASLTGVVSMLFGFPYLTQFFDYFHIPLLGEVELTTALPF
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHCCCH
DLGVYFVVVGSALTIILTIAEDDN
HHHHHHHHHHHHHHEEEEEECCCC
>Mature Secondary Structure
MKQVKPNDVMLQTFARMLIFIILAFSIYLLLAGHNSPGGGFIGGLMTASAILILYLAFDM
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
KTIRKSIPIDFVKIIGIGLLFASLTGVVSMLFGFPYLTQFFDYFHIPLLGEVELTTALPF
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHCCCH
DLGVYFVVVGSALTIILTIAEDDN
HHHHHHHHHHHHHHEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11356194 [H]