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The map label for this gene is spoIVB [H]

Identifier: 23099328

GI number: 23099328

Start: 1907152

End: 1908357

Strand: Reverse

Name: spoIVB [H]

Synonym: OB1873

Alternate gene names: 23099328

Gene position: 1908357-1907152 (Counterclockwise)

Preceding gene: 23099329

Following gene: 23099327

Centisome position: 52.56

GC content: 35.32

Gene sequence:

>1206_bases
GTGCAGAATAGAACAAAAAACTTCATAAAACGGTTCGTACTATTTTTAGTAATTACCTTTGTAGTATCTTCTATGTTTGT
TTATCCAAAAATGACCATAGCTGATCATATAGATTCTGAATTAGTTCAATCGACTAGTACTACTAAAGAAATTCAAAAAG
TCTTTCCAGATGCTGCTCCAGCTCCTAAAAAGAATACAGGGGATGAACCACCACGAAATTTGCAAGATGTGAAAGTAATC
CCTGGGGGACAATCAATAGGAGTTCAACTGGAAACAAAAGGAGTTCTGGTAGTTGGACACCATTTAGTAAATGGAAATAA
AGGGGATATTTCTCCAGGAGAAAAAGCAAAAATTAATGTAGGCGATGTGATCGTTAAAATCAATGGGGAAAAAATTAAAG
AAATGAGCGACATTAAATCCTATGTAGAAGAAGCTGGTAAGAATAAGAAAATGATGGATGTTACCGTAAAAAGGGGCAAA
AGTACAATTGACACTAAGCTTGAACCTGTATTAGATGAGAAAGAAAAACAATTCAAAATAGGACTGTATATTAGAGATTC
AGCAGCCGGTATAGGCACTATGACTTTTTATGACCCCGTAAGCGGTAAGTATGGAGCATTGGGTCATGTGATCTCTGATA
TGGATACAAAGAAACCTATTGAAATAGAAGATGGATCGATTGTTCATTCTTCAGTGACTTCCATTGAAAAAGGAGATAAT
GGTATACCTGGCGAAAAACAGGCAAGATTTGAAGAAGGCAACCATCGAATTGGTTCCATAAAAAGAAATACAGATTATGG
AATATTTGGAGTGTTAGAGAAGGAAATTGATCACGAGAAATACAACAAACCTTTCCCTGTAGCTTTATCACATGAAGTAG
AAGAAGGACCAGCAAAAATTTTAACTGTTATAAATGGAGAAGAAATTGAAGAATTTGATATTGAAATTGTGAGTAGTGTA
CCACAAAATAACCCATCTACTAAAGGAATGGTAATTCAAATTACAGATCCAAAATTATTAAAAGAAACAGGTGGAATTGT
TCAAGGCATGAGTGGAAGTCCAATCATTCAAAATGGAAAGGTAATTGGAGCGGTAACACATGTTTTTGTAAATGATCCAA
CTTCTGGTTACGGTGTTCATATTGAATGGATGTTGCAAGATGCAGATATTATTCCGCACCGCGAGGAGAAACAAACAGCA
GCTTAA

Upstream 100 bases:

>100_bases
CATTTCACATAGGTTGTTCCAGTTTAAAGATTTGTCAAATGCAGAAATTATAAGTACATAAAAAAGAACAAATCGATGGT
TGGAAGAGGAGAGTGATGAC

Downstream 100 bases:

>100_bases
TAAATGCTTGTAGTGGTTAAGCCATTACAAGCATTTTAATTTGCGTTTTTTTTAGATAAAAGCACTGCAATTTGAAAATA
TTTCATGCCATATTTCATGC

Product: stage IV sporulation protein B

Products: NA

Alternate protein names: Sporulation factor IV B protease; Stage IV sporulation protein B [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MQNRTKNFIKRFVLFLVITFVVSSMFVYPKMTIADHIDSELVQSTSTTKEIQKVFPDAAPAPKKNTGDEPPRNLQDVKVI
PGGQSIGVQLETKGVLVVGHHLVNGNKGDISPGEKAKINVGDVIVKINGEKIKEMSDIKSYVEEAGKNKKMMDVTVKRGK
STIDTKLEPVLDEKEKQFKIGLYIRDSAAGIGTMTFYDPVSGKYGALGHVISDMDTKKPIEIEDGSIVHSSVTSIEKGDN
GIPGEKQARFEEGNHRIGSIKRNTDYGIFGVLEKEIDHEKYNKPFPVALSHEVEEGPAKILTVINGEEIEEFDIEIVSSV
PQNNPSTKGMVIQITDPKLLKETGGIVQGMSGSPIIQNGKVIGAVTHVFVNDPTSGYGVHIEWMLQDADIIPHREEKQTA
A

Sequences:

>Translated_401_residues
MQNRTKNFIKRFVLFLVITFVVSSMFVYPKMTIADHIDSELVQSTSTTKEIQKVFPDAAPAPKKNTGDEPPRNLQDVKVI
PGGQSIGVQLETKGVLVVGHHLVNGNKGDISPGEKAKINVGDVIVKINGEKIKEMSDIKSYVEEAGKNKKMMDVTVKRGK
STIDTKLEPVLDEKEKQFKIGLYIRDSAAGIGTMTFYDPVSGKYGALGHVISDMDTKKPIEIEDGSIVHSSVTSIEKGDN
GIPGEKQARFEEGNHRIGSIKRNTDYGIFGVLEKEIDHEKYNKPFPVALSHEVEEGPAKILTVINGEEIEEFDIEIVSSV
PQNNPSTKGMVIQITDPKLLKETGGIVQGMSGSPIIQNGKVIGAVTHVFVNDPTSGYGVHIEWMLQDADIIPHREEKQTA
A
>Mature_401_residues
MQNRTKNFIKRFVLFLVITFVVSSMFVYPKMTIADHIDSELVQSTSTTKEIQKVFPDAAPAPKKNTGDEPPRNLQDVKVI
PGGQSIGVQLETKGVLVVGHHLVNGNKGDISPGEKAKINVGDVIVKINGEKIKEMSDIKSYVEEAGKNKKMMDVTVKRGK
STIDTKLEPVLDEKEKQFKIGLYIRDSAAGIGTMTFYDPVSGKYGALGHVISDMDTKKPIEIEDGSIVHSSVTSIEKGDN
GIPGEKQARFEEGNHRIGSIKRNTDYGIFGVLEKEIDHEKYNKPFPVALSHEVEEGPAKILTVINGEEIEEFDIEIVSSV
PQNNPSTKGMVIQITDPKLLKETGGIVQGMSGSPIIQNGKVIGAVTHVFVNDPTSGYGVHIEWMLQDADIIPHREEKQTA
A

Specific function: Plays a central role in the sigma-K checkpoint which coordinates gene expression during the later stages of spore formation. The protease is activated by trans cleavage of the zymogen precursor producing SpoIVB-45 kDa. This undergoes further trimming by c

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Forespore intermembrane space [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 peptidase S55 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR014219
- InterPro:   IPR008763 [H]

Pfam domain/function: PF00595 PDZ; PF05580 Peptidase_S55 [H]

EC number: =3.4.21.116 [H]

Molecular weight: Translated: 43956; Mature: 43956

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS50106 PDZ ; PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNRTKNFIKRFVLFLVITFVVSSMFVYPKMTIADHIDSELVQSTSTTKEIQKVFPDAAP
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCC
APKKNTGDEPPRNLQDVKVIPGGQSIGVQLETKGVLVVGHHLVNGNKGDISPGEKAKINV
CCCCCCCCCCCCCCCCEEEECCCCEEEEEEECCCEEEEEEEEECCCCCCCCCCCCCEEEE
GDVIVKINGEKIKEMSDIKSYVEEAGKNKKMMDVTVKRGKSTIDTKLEPVLDEKEKQFKI
CEEEEEECCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHCCCCHHHCCCCCEEEE
GLYIRDSAAGIGTMTFYDPVSGKYGALGHVISDMDTKKPIEIEDGSIVHSSVTSIEKGDN
EEEEECCCCCCEEEEEECCCCCCCCHHHHHHHCCCCCCCEEECCCCEEEHHHHHHHCCCC
GIPGEKQARFEEGNHRIGSIKRNTDYGIFGVLEKEIDHEKYNKPFPVALSHEVEEGPAKI
CCCCCHHHHHHCCCCEEEEEEECCCCCEEEHHHHHHHHHHCCCCCCEEECCCCCCCCEEE
LTVINGEEIEEFDIEIVSSVPQNNPSTKGMVIQITDPKLLKETGGIVQGMSGSPIIQNGK
EEEECCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHCCCEEECCCCCCEEECCE
VIGAVTHVFVNDPTSGYGVHIEWMLQDADIIPHREEKQTAA
EEEEEEEEEECCCCCCCEEEEEEEEECCCCCCCCCHHCCCC
>Mature Secondary Structure
MQNRTKNFIKRFVLFLVITFVVSSMFVYPKMTIADHIDSELVQSTSTTKEIQKVFPDAAP
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCC
APKKNTGDEPPRNLQDVKVIPGGQSIGVQLETKGVLVVGHHLVNGNKGDISPGEKAKINV
CCCCCCCCCCCCCCCCEEEECCCCEEEEEEECCCEEEEEEEEECCCCCCCCCCCCCEEEE
GDVIVKINGEKIKEMSDIKSYVEEAGKNKKMMDVTVKRGKSTIDTKLEPVLDEKEKQFKI
CEEEEEECCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHCCCCHHHCCCCCEEEE
GLYIRDSAAGIGTMTFYDPVSGKYGALGHVISDMDTKKPIEIEDGSIVHSSVTSIEKGDN
EEEEECCCCCCEEEEEECCCCCCCCHHHHHHHCCCCCCCEEECCCCEEEHHHHHHHCCCC
GIPGEKQARFEEGNHRIGSIKRNTDYGIFGVLEKEIDHEKYNKPFPVALSHEVEEGPAKI
CCCCCHHHHHHCCCCEEEEEEECCCCCEEEHHHHHHHHHHCCCCCCEEECCCCCCCCEEE
LTVINGEEIEEFDIEIVSSVPQNNPSTKGMVIQITDPKLLKETGGIVQGMSGSPIIQNGK
EEEECCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHCCCEEECCCCCCEEECCE
VIGAVTHVFVNDPTSGYGVHIEWMLQDADIIPHREEKQTAA
EEEEEEEEEECCCCCCCEEEEEEEEECCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2106508; 8969508; 9384377; 11741860 [H]