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The map label for this gene is resA

Identifier: 23099277

GI number: 23099277

Start: 1859217

End: 1859795

Strand: Reverse

Name: resA

Synonym: OB1822

Alternate gene names: 23099277

Gene position: 1859795-1859217 (Counterclockwise)

Preceding gene: 23099278

Following gene: 23099276

Centisome position: 51.23

GC content: 33.51

Gene sequence:

>579_bases
TTGGATATTCAACAAAATAAGACAAATAAACAGAAGAAAAAAAGAAATCGCTTCATTTTCAGGTCATCCATATTACTTAT
TTTAGTAGCAGCAGTAGTATTCGCTATTGTTTCTAATATGAAAGATGATAATAAAATATATCGTGTTGGTGATGCTGCCC
CCGATTTTCAACTGAAACAGATTAGCGAAGAGGTTGACCAATCAACTGTTCAGTTAAGTGATTTAGAGGGGAAAGGTGTC
ATGCTAAACTTTTGGGCTACATGGTGTGACCCTTGTAAAGCAGAAATGCCTTATATGCAAGACTTATATGCGGAATATAA
AGAAAAAGGTGTTGAAATTGTTGCAGTAAGTTTAGATGGGACAGAATTGGTTGTAGATCAATTTATTGATGAATATGACT
TAACATTTCCGGTTCCTCATGATAAAAATGGAGAGGTAAAAGATCTTTATAAAATTGGTCCGATGCCTACAACTTATTTT
ATTAAACCAAATGGGGAAATAGAAGAGATTGTTCAAGGGGCACTAACTTTAGATAGATTAGAAGGCTATTTAAATGATAT
TGCTCCACAACAGAATTAA

Upstream 100 bases:

>100_bases
GAAGTCAACCAATTACGTGCACAAGCTCAAAAATTGTAAGATAATGGTCAAATTTATAAATAGTCTTAAATGATATAATG
ACCTGGGAGGGAGTGTTACA

Downstream 100 bases:

>100_bases
GAAAGGCCTTGGGATGGAGGGATAGTATGAATAAGATAAAATGTGAGTGTGGTCATGTTAATCCCGAAGGAACAGTATTA
TGTGAATCTTGTGGAAAACC

Product: thiol-disulfide oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MDIQQNKTNKQKKKRNRFIFRSSILLILVAAVVFAIVSNMKDDNKIYRVGDAAPDFQLKQISEEVDQSTVQLSDLEGKGV
MLNFWATWCDPCKAEMPYMQDLYAEYKEKGVEIVAVSLDGTELVVDQFIDEYDLTFPVPHDKNGEVKDLYKIGPMPTTYF
IKPNGEIEEIVQGALTLDRLEGYLNDIAPQQN

Sequences:

>Translated_192_residues
MDIQQNKTNKQKKKRNRFIFRSSILLILVAAVVFAIVSNMKDDNKIYRVGDAAPDFQLKQISEEVDQSTVQLSDLEGKGV
MLNFWATWCDPCKAEMPYMQDLYAEYKEKGVEIVAVSLDGTELVVDQFIDEYDLTFPVPHDKNGEVKDLYKIGPMPTTYF
IKPNGEIEEIVQGALTLDRLEGYLNDIAPQQN
>Mature_192_residues
MDIQQNKTNKQKKKRNRFIFRSSILLILVAAVVFAIVSNMKDDNKIYRVGDAAPDFQLKQISEEVDQSTVQLSDLEGKGV
MLNFWATWCDPCKAEMPYMQDLYAEYKEKGVEIVAVSLDGTELVVDQFIDEYDLTFPVPHDKNGEVKDLYKIGPMPTTYF
IKPNGEIEEIVQGALTLDRLEGYLNDIAPQQN

Specific function: Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalent

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane (By similarity)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RESA_OCEIH (Q8CXF3)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_692743.1
- ProteinModelPortal:   Q8CXF3
- SMR:   Q8CXF3
- GeneID:   1018316
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB1822
- NMPDR:   fig|221109.1.peg.1823
- HOGENOM:   HBG493509
- OMA:   IITGTMT
- ProtClustDB:   PRK03147
- BioCyc:   OIHE221109:OB1822-MONOMER
- HAMAP:   MF_01319
- InterPro:   IPR000866
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335
- Gene3D:   G3DSA:3.40.30.10

Pfam domain/function: PF00578 AhpC-TSA; SSF52833 Thiordxn-like_fd

EC number: NA

Molecular weight: Translated: 21904; Mature: 21904

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS00194 THIOREDOXIN_1; PS51352 THIOREDOXIN_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe8ad114)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIQQNKTNKQKKKRNRFIFRSSILLILVAAVVFAIVSNMKDDNKIYRVGDAAPDFQLKQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHH
ISEEVDQSTVQLSDLEGKGVMLNFWATWCDPCKAEMPYMQDLYAEYKEKGVEIVAVSLDG
HHHHHHHHHEEEECCCCCCEEEEEHHHHCCCCCCCCCHHHHHHHHHHHCCEEEEEEECCC
TELVVDQFIDEYDLTFPVPHDKNGEVKDLYKIGPMPTTYFIKPNGEIEEIVQGALTLDRL
HHHHHHHHHHHCCCEECCCCCCCCCHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHH
EGYLNDIAPQQN
HHHHHHCCCCCH
>Mature Secondary Structure
MDIQQNKTNKQKKKRNRFIFRSSILLILVAAVVFAIVSNMKDDNKIYRVGDAAPDFQLKQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHH
ISEEVDQSTVQLSDLEGKGVMLNFWATWCDPCKAEMPYMQDLYAEYKEKGVEIVAVSLDG
HHHHHHHHHEEEECCCCCCEEEEEHHHHCCCCCCCCCHHHHHHHHHHHCCEEEEEEECCC
TELVVDQFIDEYDLTFPVPHDKNGEVKDLYKIGPMPTTYFIKPNGEIEEIVQGALTLDRL
HHHHHHHHHHHCCCEECCCCCCCCCHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHH
EGYLNDIAPQQN
HHHHHHCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12235376