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The map label for this gene is lytT

Identifier: 23099096

GI number: 23099096

Start: 1681173

End: 1681913

Strand: Reverse

Name: lytT

Synonym: OB1641

Alternate gene names: 23099096

Gene position: 1681913-1681173 (Counterclockwise)

Preceding gene: 23099097

Following gene: 23099095

Centisome position: 46.33

GC content: 32.39

Gene sequence:

>741_bases
TTGAAAATTCATATCATGATTGCAGAAGATGAACGATTAGCAAGAGAGGAGCTTATGTATCTTTTGCAACAAGAAAATGA
TATTATATTATGCCCTAGTGCAGAAAATGGAGATCAATTACTTAACTTATATCAAGAATACAATCCCAATGTCATTTTTC
TCGATATCCATATGCCTGGAATAAATGGAATTGAGGTTGCTAAAAAAATACGAAACGAGTTTGAAGATAAAGATATAATT
ATTATTTTCACTACAGCTTATGAATCTTACGGTGTACAAGCGTTTGAAATACAAGCAACTGATTATTTATTAAAACCATT
TAGCGAAGAAAGATTCAAAATTGCAATGAATCGAATTCGAAAGACTTTATCTACTAAAAAGGTAAGGAAGCCAAAAGTCG
ATAAATTAGTGGTGAATCTCGATGAAAAGATGATGGTCATTGACCCTAATCAAATTGGATTCGCTGCTCGTGAAGGGCGC
ACTGTAAAAATACATTTTATATCAAATGAAGTAATTGAAACCAAAATGAATCTTAAAGAATTAGAAGAAAAGCTTTCTGG
TTTTCCCTTTTATCGCCCACATCGAAGTTACTTAGTAAATATGGATTGTATCAAAGAAATTACTCCATGGTTTAATGGCG
CCTATAATTTAGTAATTAAAGACCTAGCTGAATCAACAATACCGGTTAGCAGAACTGCTGCTAAAGGGTTATTTGATGCA
TTACAAGGTGTACACCATTAA

Upstream 100 bases:

>100_bases
TCAAAATACAGACAAAGGAAGCATGGTCCAATTTATACTACCATATCGTAACTGTAAGAAAATCATGTGATCATGCAATA
AAATTGAGGAGGTGTATATA

Downstream 100 bases:

>100_bases
TACAATTTAAAACGCTATACTACAACTTAACCCTCATATCCTACATTTTAGGTTTAAATTTAAAATAAATAGAATCATTT
ACAATATACTGAATTCATAG

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MKIHIMIAEDERLAREELMYLLQQENDIILCPSAENGDQLLNLYQEYNPNVIFLDIHMPGINGIEVAKKIRNEFEDKDII
IIFTTAYESYGVQAFEIQATDYLLKPFSEERFKIAMNRIRKTLSTKKVRKPKVDKLVVNLDEKMMVIDPNQIGFAAREGR
TVKIHFISNEVIETKMNLKELEEKLSGFPFYRPHRSYLVNMDCIKEITPWFNGAYNLVIKDLAESTIPVSRTAAKGLFDA
LQGVHH

Sequences:

>Translated_246_residues
MKIHIMIAEDERLAREELMYLLQQENDIILCPSAENGDQLLNLYQEYNPNVIFLDIHMPGINGIEVAKKIRNEFEDKDII
IIFTTAYESYGVQAFEIQATDYLLKPFSEERFKIAMNRIRKTLSTKKVRKPKVDKLVVNLDEKMMVIDPNQIGFAAREGR
TVKIHFISNEVIETKMNLKELEEKLSGFPFYRPHRSYLVNMDCIKEITPWFNGAYNLVIKDLAESTIPVSRTAAKGLFDA
LQGVHH
>Mature_246_residues
MKIHIMIAEDERLAREELMYLLQQENDIILCPSAENGDQLLNLYQEYNPNVIFLDIHMPGINGIEVAKKIRNEFEDKDII
IIFTTAYESYGVQAFEIQATDYLLKPFSEERFKIAMNRIRKTLSTKKVRKPKVDKLVVNLDEKMMVIDPNQIGFAAREGR
TVKIHFISNEVIETKMNLKELEEKLSGFPFYRPHRSYLVNMDCIKEITPWFNGAYNLVIKDLAESTIPVSRTAAKGLFDA
LQGVHH

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain

Homologues:

Organism=Escherichia coli, GI1788724, Length=238, Percent_Identity=32.3529411764706, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI87082052, Length=246, Percent_Identity=31.7073170731707, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1786599, Length=126, Percent_Identity=34.9206349206349, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790863, Length=132, Percent_Identity=29.5454545454545, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LYTT_OCEIH (Q8EQQ3)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_692562.1
- ProteinModelPortal:   Q8EQQ3
- GeneID:   1018136
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB1641
- NMPDR:   fig|221109.1.peg.1643
- HOGENOM:   HBG753323
- OMA:   TDSEEYI
- ProtClustDB:   CLSK904689
- BioCyc:   OIHE221109:OB1641-MONOMER
- GO:   GO:0005737
- GO:   GO:0006350
- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789
- SMART:   SM00850
- SMART:   SM00448

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg; SSF52172 CheY_like

EC number: NA

Molecular weight: Translated: 28511; Mature: 28511

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS50930 HTH_LYTTR; PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIHIMIAEDERLAREELMYLLQQENDIILCPSAENGDQLLNLYQEYNPNVIFLDIHMPG
CEEEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCEEEEEEECCC
INGIEVAKKIRNEFEDKDIIIIFTTAYESYGVQAFEIQATDYLLKPFSEERFKIAMNRIR
CCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEECCHHHHCCCCHHHHHHHHHHHH
KTLSTKKVRKPKVDKLVVNLDEKMMVIDPNQIGFAAREGRTVKIHFISNEVIETKMNLKE
HHHHHHHCCCCCHHEEEEECCCEEEEECCCCCCEEECCCCEEEEEEECCHHHHHHCCHHH
LEEKLSGFPFYRPHRSYLVNMDCIKEITPWFNGAYNLVIKDLAESTIPVSRTAAKGLFDA
HHHHHCCCCCCCCCHHEEECHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
LQGVHH
HHHCCC
>Mature Secondary Structure
MKIHIMIAEDERLAREELMYLLQQENDIILCPSAENGDQLLNLYQEYNPNVIFLDIHMPG
CEEEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCEEEEEEECCC
INGIEVAKKIRNEFEDKDIIIIFTTAYESYGVQAFEIQATDYLLKPFSEERFKIAMNRIR
CCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEECCHHHHCCCCHHHHHHHHHHHH
KTLSTKKVRKPKVDKLVVNLDEKMMVIDPNQIGFAAREGRTVKIHFISNEVIETKMNLKE
HHHHHHHCCCCCHHEEEEECCCEEEEECCCCCCEEECCCCEEEEEEECCHHHHHHCCHHH
LEEKLSGFPFYRPHRSYLVNMDCIKEITPWFNGAYNLVIKDLAESTIPVSRTAAKGLFDA
HHHHHCCCCCCCCCHHEEECHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
LQGVHH
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376