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The map label for this gene is flhA [H]

Identifier: 23099030

GI number: 23099030

Start: 1612725

End: 1614758

Strand: Direct

Name: flhA [H]

Synonym: OB1575

Alternate gene names: 23099030

Gene position: 1612725-1614758 (Clockwise)

Preceding gene: 23099029

Following gene: 23099031

Centisome position: 44.42

GC content: 36.87

Gene sequence:

>2034_bases
ATGAAAGCGCGAGATATATCCGTCCTTCTGGGAGTTATATTAGTAATTATCATGTTAGTGATTCCGCTGCCAGGAGCACT
TCTTAGCTTTTTTATATTAATTAATATTATCTTAGCGCTAATCGTTATTTTAGTTGCAATGAATACGACCGAGCCATTGC
AATTTGGAGTATTTCCAACATTAATCTTACTGTTAACTTTATTTCGACTTGCGTTAAATGTATCTACAACTAGATCGATA
CTCTCTGAAGCAGAAGCTGGTGGAGTCGTTGATACATTTGGAACGTTTGTTATTGGAGATAATCCTTTTGTTGGTTTTGT
TGTATTTATCATATTAGTAATTATTAATTTCTTAGTTATTACAAAAGGTTCTGAGCGAGTTTCTGAAGTGGCTGCAAGAT
TTTCTCTTGATGCGATGCCAGGAAAGCAAATGAGTGTTGATGCTGATTTAAATGCTGGCCTGATTTCCGAAGCGCAAGCA
AAAGAACGTCGTGAAAAAATTGAAAGAGAAGCAGATTTCCATGGCTCTATGGATGGAGCTAGTAAATTTGTGAAAGGGGA
CGCCATTGCTGGAATTATAATCGTCATCATCAATATATTATTTGGCTTAATTATTGGGATGGTGCAAATGGGAATGTCCA
TGGATGAGGCAGTAAACACTTTTATGAGATTAACGGTAGGTGATGGTTTAGTAAGTCAGATTCCCGCACTTTTAATTTCT
ACTGCCACAGGTATTGTAGTTACACGTTCTGCAGGTAGCAATAACTTAAGTGCTGATGTTATGGATCAATTATTACAGTT
CCCTAAGTTACTTTATATCGCAGGAGGTACTATCTTCCTCTTAGGACTAACCCCGATTAATTTCTTCTTAACCACAAGCT
TGGCAGCGATTTTAATATTAGGTGGATATTGGATGCAAAACCGAGCGACGAAGGAGGAAGAGCCAACTGTTGAAGAGGAA
GAAGAAACGGAATCTACCGCTTTAAAACAACCAGAAAATGTCGTTAGTTTATTGAATATGGACCCTATCGAGTTTGAATT
TGGTTATGGGTTGATTCCACTTGCTGACACAGCTCAAGGTGGGGATTTACTTGATCGTGTAATTATGATTCGTCGTCAAC
TAGCCATTGAGTTAGGTTTAGTTATCCCGGTAGTACGAATTAGAGATAATATTCAATTAAACCCTAATGAATACCGATTA
AAAATCAAGGGTAATGAAGTTGCTAATGGAGAATTAATGTTAGATCACTATCTAGCAATGACTCCAGACTTTGGCGAAGA
AGAAATAGACGGAATTGACACGAAGGAACCGGCTTTTGGATTACCTGCAAAGTGGATTAATGAGGATGTAAAGGATGAGG
CGGAATTATCTGGCTTCACAGTGGTTGATCCACCTTCTGTAGTGTCTACACATATTACAGAAGTAATTAAACGTCATGCA
CATCAATTATTAGGTAGAGAAGAAACAAAACAATTAATTGACCACTTGAAAGAAAGTAATCCAATTTTAGTAGAAGAAGT
TACACCAGAACCATTATCTACAGGTGATATACAAAAAGTACTTGCAAAACTTCTACGTGAAAGTGTCTCGATTCGTAATT
TACCGATCATTTTTGAGACATTAGCTGATTTTTCTAAAATGACGAATGATACAGAATTACTTGGGGAATACGTGAGGCAA
TCACTATCTGCTCAGATTACGAAAAACTACGCTCAAGAAAATAATCAAATGAAAGTGATAACTGTATCAGGAAAGGTAGA
AAAAACCATCGCTGATAACATTCAGCAAACGGAACATGGGAATTTTTTGTCTTTAGATCCAGAAACACAGCAACAAATTA
TAAAGACCATTCATGCGGAAGCAGAAAAATTATCATTACAAGAAGAAACAACCATTCTTATATGCTCGCCCGCTATAAGA
ATGTACTTAAAACAGTTACTAGACCGATTTTTACCTCAAGTCGTTGTGCTATCGTACAATGAACTCGAACCAACTGTTGA
AGTTCAAAGTGTAGGGGTGGTGAATATAGCATGA

Upstream 100 bases:

>100_bases
GGAGAAATAATACCTGAAGCATACTTTCAAGCAGTAGCAGAAGTATTAGCTTATGTGTACCGAATGGAGAAAAAAGCATA
ACAAGTTAGGAGAGAGTTGT

Downstream 100 bases:

>100_bases
AAATAAAAAAATATACAGCACCAACAATGCCAGAAGTGATGAAAGAAGTAAGGAAAGATTTTGGAACGGACGCAGTAATT
TTACAATCAAAAGAAGTTAA

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 677; Mature: 677

Protein sequence:

>677_residues
MKARDISVLLGVILVIIMLVIPLPGALLSFFILINIILALIVILVAMNTTEPLQFGVFPTLILLLTLFRLALNVSTTRSI
LSEAEAGGVVDTFGTFVIGDNPFVGFVVFIILVIINFLVITKGSERVSEVAARFSLDAMPGKQMSVDADLNAGLISEAQA
KERREKIEREADFHGSMDGASKFVKGDAIAGIIIVIINILFGLIIGMVQMGMSMDEAVNTFMRLTVGDGLVSQIPALLIS
TATGIVVTRSAGSNNLSADVMDQLLQFPKLLYIAGGTIFLLGLTPINFFLTTSLAAILILGGYWMQNRATKEEEPTVEEE
EETESTALKQPENVVSLLNMDPIEFEFGYGLIPLADTAQGGDLLDRVIMIRRQLAIELGLVIPVVRIRDNIQLNPNEYRL
KIKGNEVANGELMLDHYLAMTPDFGEEEIDGIDTKEPAFGLPAKWINEDVKDEAELSGFTVVDPPSVVSTHITEVIKRHA
HQLLGREETKQLIDHLKESNPILVEEVTPEPLSTGDIQKVLAKLLRESVSIRNLPIIFETLADFSKMTNDTELLGEYVRQ
SLSAQITKNYAQENNQMKVITVSGKVEKTIADNIQQTEHGNFLSLDPETQQQIIKTIHAEAEKLSLQEETTILICSPAIR
MYLKQLLDRFLPQVVVLSYNELEPTVEVQSVGVVNIA

Sequences:

>Translated_677_residues
MKARDISVLLGVILVIIMLVIPLPGALLSFFILINIILALIVILVAMNTTEPLQFGVFPTLILLLTLFRLALNVSTTRSI
LSEAEAGGVVDTFGTFVIGDNPFVGFVVFIILVIINFLVITKGSERVSEVAARFSLDAMPGKQMSVDADLNAGLISEAQA
KERREKIEREADFHGSMDGASKFVKGDAIAGIIIVIINILFGLIIGMVQMGMSMDEAVNTFMRLTVGDGLVSQIPALLIS
TATGIVVTRSAGSNNLSADVMDQLLQFPKLLYIAGGTIFLLGLTPINFFLTTSLAAILILGGYWMQNRATKEEEPTVEEE
EETESTALKQPENVVSLLNMDPIEFEFGYGLIPLADTAQGGDLLDRVIMIRRQLAIELGLVIPVVRIRDNIQLNPNEYRL
KIKGNEVANGELMLDHYLAMTPDFGEEEIDGIDTKEPAFGLPAKWINEDVKDEAELSGFTVVDPPSVVSTHITEVIKRHA
HQLLGREETKQLIDHLKESNPILVEEVTPEPLSTGDIQKVLAKLLRESVSIRNLPIIFETLADFSKMTNDTELLGEYVRQ
SLSAQITKNYAQENNQMKVITVSGKVEKTIADNIQQTEHGNFLSLDPETQQQIIKTIHAEAEKLSLQEETTILICSPAIR
MYLKQLLDRFLPQVVVLSYNELEPTVEVQSVGVVNIA
>Mature_677_residues
MKARDISVLLGVILVIIMLVIPLPGALLSFFILINIILALIVILVAMNTTEPLQFGVFPTLILLLTLFRLALNVSTTRSI
LSEAEAGGVVDTFGTFVIGDNPFVGFVVFIILVIINFLVITKGSERVSEVAARFSLDAMPGKQMSVDADLNAGLISEAQA
KERREKIEREADFHGSMDGASKFVKGDAIAGIIIVIINILFGLIIGMVQMGMSMDEAVNTFMRLTVGDGLVSQIPALLIS
TATGIVVTRSAGSNNLSADVMDQLLQFPKLLYIAGGTIFLLGLTPINFFLTTSLAAILILGGYWMQNRATKEEEPTVEEE
EETESTALKQPENVVSLLNMDPIEFEFGYGLIPLADTAQGGDLLDRVIMIRRQLAIELGLVIPVVRIRDNIQLNPNEYRL
KIKGNEVANGELMLDHYLAMTPDFGEEEIDGIDTKEPAFGLPAKWINEDVKDEAELSGFTVVDPPSVVSTHITEVIKRHA
HQLLGREETKQLIDHLKESNPILVEEVTPEPLSTGDIQKVLAKLLRESVSIRNLPIIFETLADFSKMTNDTELLGEYVRQ
SLSAQITKNYAQENNQMKVITVSGKVEKTIADNIQQTEHGNFLSLDPETQQQIIKTIHAEAEKLSLQEETTILICSPAIR
MYLKQLLDRFLPQVVVLSYNELEPTVEVQSVGVVNIA

Specific function: Involved in the export of flagellum proteins [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=678, Percent_Identity=42.1828908554572, Blast_Score=483, Evalue=1e-137,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 74459; Mature: 74459

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKARDISVLLGVILVIIMLVIPLPGALLSFFILINIILALIVILVAMNTTEPLQFGVFPT
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LILLLTLFRLALNVSTTRSILSEAEAGGVVDTFGTFVIGDNPFVGFVVFIILVIINFLVI
HHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHCCCEEECCCCHHHHHHHHHHHHHHHHHH
TKGSERVSEVAARFSLDAMPGKQMSVDADLNAGLISEAQAKERREKIEREADFHGSMDGA
CCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHH
SKFVKGDAIAGIIIVIINILFGLIIGMVQMGMSMDEAVNTFMRLTVGDGLVSQIPALLIS
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
TATGIVVTRSAGSNNLSADVMDQLLQFPKLLYIAGGTIFLLGLTPINFFLTTSLAAILIL
HCCCEEEEECCCCCCCCHHHHHHHHHCCHHEEEECCEEEEEECCHHHHHHHHHHHHHHHH
GGYWMQNRATKEEEPTVEEEEETESTALKQPENVVSLLNMDPIEFEFGYGLIPLADTAQG
HCHHHCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHCCCCCEEECCCCEEECCCCCCC
GDLLDRVIMIRRQLAIELGLVIPVVRIRDNIQLNPNEYRLKIKGNEVANGELMLDHYLAM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCEEEEEEECCEECCCCEEEHHHHHC
TPDFGEEEIDGIDTKEPAFGLPAKWINEDVKDEAELSGFTVVDPPSVVSTHITEVIKRHA
CCCCCCHHCCCCCCCCCCCCCCHHHHCCHHCCHHHCCCCEEECCHHHHHHHHHHHHHHHH
HQLLGREETKQLIDHLKESNPILVEEVTPEPLSTGDIQKVLAKLLRESVSIRNLPIIFET
HHHHCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHH
LADFSKMTNDTELLGEYVRQSLSAQITKNYAQENNQMKVITVSGKVEKTIADNIQQTEHG
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCC
NFLSLDPETQQQIIKTIHAEAEKLSLQEETTILICSPAIRMYLKQLLDRFLPQVVVLSYN
CEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHEEHCCC
ELEPTVEVQSVGVVNIA
CCCCCEEEECCCEEECC
>Mature Secondary Structure
MKARDISVLLGVILVIIMLVIPLPGALLSFFILINIILALIVILVAMNTTEPLQFGVFPT
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LILLLTLFRLALNVSTTRSILSEAEAGGVVDTFGTFVIGDNPFVGFVVFIILVIINFLVI
HHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHCCCEEECCCCHHHHHHHHHHHHHHHHHH
TKGSERVSEVAARFSLDAMPGKQMSVDADLNAGLISEAQAKERREKIEREADFHGSMDGA
CCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHH
SKFVKGDAIAGIIIVIINILFGLIIGMVQMGMSMDEAVNTFMRLTVGDGLVSQIPALLIS
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
TATGIVVTRSAGSNNLSADVMDQLLQFPKLLYIAGGTIFLLGLTPINFFLTTSLAAILIL
HCCCEEEEECCCCCCCCHHHHHHHHHCCHHEEEECCEEEEEECCHHHHHHHHHHHHHHHH
GGYWMQNRATKEEEPTVEEEEETESTALKQPENVVSLLNMDPIEFEFGYGLIPLADTAQG
HCHHHCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHCCCCCEEECCCCEEECCCCCCC
GDLLDRVIMIRRQLAIELGLVIPVVRIRDNIQLNPNEYRLKIKGNEVANGELMLDHYLAM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCEEEEEEECCEECCCCEEEHHHHHC
TPDFGEEEIDGIDTKEPAFGLPAKWINEDVKDEAELSGFTVVDPPSVVSTHITEVIKRHA
CCCCCCHHCCCCCCCCCCCCCCHHHHCCHHCCHHHCCCCEEECCHHHHHHHHHHHHHHHH
HQLLGREETKQLIDHLKESNPILVEEVTPEPLSTGDIQKVLAKLLRESVSIRNLPIIFET
HHHHCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHH
LADFSKMTNDTELLGEYVRQSLSAQITKNYAQENNQMKVITVSGKVEKTIADNIQQTEHG
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCC
NFLSLDPETQQQIIKTIHAEAEKLSLQEETTILICSPAIRMYLKQLLDRFLPQVVVLSYN
CEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHEEHCCC
ELEPTVEVQSVGVVNIA
CCCCCEEEECCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8097015; 9384377 [H]