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The map label for this gene is flhF [H]

Identifier: 23099031

GI number: 23099031

Start: 1614755

End: 1615873

Strand: Direct

Name: flhF [H]

Synonym: OB1576

Alternate gene names: 23099031

Gene position: 1614755-1615873 (Clockwise)

Preceding gene: 23099030

Following gene: 23099032

Centisome position: 44.48

GC content: 33.33

Gene sequence:

>1119_bases
ATGAAAATAAAAAAATATACAGCACCAACAATGCCAGAAGTGATGAAAGAAGTAAGGAAAGATTTTGGAACGGACGCAGT
AATTTTACAATCAAAAGAAGTTAAAAAGGGCGGTTTACTTGGGATGTTTAAAAAGACATTCATTGAAGTTGTAGCTGGAG
TTGATCCAGAACCAGTAAATAGTAAATCAATTCCTAGAGAGAAACAGATTACAGAATATAATCAAGATAATCATAATAGA
AAAACAAAAGATGAAAATCCACTTCGGGAAGAGATACTAAATATACAGCGATTGATTGAAGCACAAGGAAGACAAAGTAA
TCATGAATTTACACCCATTTATCAATTAGCTTATGAGCATCTCATAGCACAAGAAATATCACCAACCATTGCGGAACAAT
TAATTAAAGAGGTAAGAGATGATGAAACGAATCAAGATGAGTATCATAACTTAGAGTCGATTTTAATTAACGTAAAACAA
TTAATTGTTAACAGACTAGAACAAGTGGATATCGGATTTACTTATGATCATCGAATTATTCAATTTGTAGGACCGACCGG
AGTTGGAAAAACGACAACTATCGCAAAAATTGCAGCGAAACTTTATTTAGAAGAAAAAAAGAAAGTTGCATTTATTACGC
TAGATACTTATCGTATCGCCGCAGTAGATCAGTTAAAGACATATGCGAAGATATTACACATCCCAGTAGAGGTCGCTTAT
AGTAAGGAAGATTACCGAAAAGCAGTAGAGAAGTTTTCTTCTTTTGACGTAATTTTAGTAGATACTGCAGGCAGGAATTA
TCGAGATAATCAGTATTTGAACGAAATTCAAGAATGGCCGAGTTCTCTTAAAGTGACTAATTATTTAGTGCTGTCGATGA
CCTCAAAGCCTAAAGATATGTTAGATATCTTTCAGCGGTTTCAATTACTCGGTATTCATGGTGTAGTCTTTACAAAATTA
GATGAGACGGAACAATACGGGAACCTATTAAACATTAGTTGGAACAATAAAATAAGAATTGGTTATATGACAAATGGACA
AGATGTTCCCGAAGATGTTATACAACCATCTGCCGAAGAAATTTCACATTTAATTTTGAGTGATAATGATGAAAGTTGA

Upstream 100 bases:

>100_bases
AACAGTTACTAGACCGATTTTTACCTCAAGTCGTTGTGCTATCGTACAATGAACTCGAACCAACTGTTGAAGTTCAAAGT
GTAGGGGTGGTGAATATAGC

Downstream 100 bases:

>100_bases
TCAAGCACAAGGGCTGCGTCAAAAACTAAATCATTCCGTTCGTCAAGCAAAAACGATAGCTGTAGTCAGTGGTAAGGGAG
GCGTAGGGAAATCAAATTTT

Product: flagellar biosynthesis regulator FlhF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MKIKKYTAPTMPEVMKEVRKDFGTDAVILQSKEVKKGGLLGMFKKTFIEVVAGVDPEPVNSKSIPREKQITEYNQDNHNR
KTKDENPLREEILNIQRLIEAQGRQSNHEFTPIYQLAYEHLIAQEISPTIAEQLIKEVRDDETNQDEYHNLESILINVKQ
LIVNRLEQVDIGFTYDHRIIQFVGPTGVGKTTTIAKIAAKLYLEEKKKVAFITLDTYRIAAVDQLKTYAKILHIPVEVAY
SKEDYRKAVEKFSSFDVILVDTAGRNYRDNQYLNEIQEWPSSLKVTNYLVLSMTSKPKDMLDIFQRFQLLGIHGVVFTKL
DETEQYGNLLNISWNNKIRIGYMTNGQDVPEDVIQPSAEEISHLILSDNDES

Sequences:

>Translated_372_residues
MKIKKYTAPTMPEVMKEVRKDFGTDAVILQSKEVKKGGLLGMFKKTFIEVVAGVDPEPVNSKSIPREKQITEYNQDNHNR
KTKDENPLREEILNIQRLIEAQGRQSNHEFTPIYQLAYEHLIAQEISPTIAEQLIKEVRDDETNQDEYHNLESILINVKQ
LIVNRLEQVDIGFTYDHRIIQFVGPTGVGKTTTIAKIAAKLYLEEKKKVAFITLDTYRIAAVDQLKTYAKILHIPVEVAY
SKEDYRKAVEKFSSFDVILVDTAGRNYRDNQYLNEIQEWPSSLKVTNYLVLSMTSKPKDMLDIFQRFQLLGIHGVVFTKL
DETEQYGNLLNISWNNKIRIGYMTNGQDVPEDVIQPSAEEISHLILSDNDES
>Mature_372_residues
MKIKKYTAPTMPEVMKEVRKDFGTDAVILQSKEVKKGGLLGMFKKTFIEVVAGVDPEPVNSKSIPREKQITEYNQDNHNR
KTKDENPLREEILNIQRLIEAQGRQSNHEFTPIYQLAYEHLIAQEISPTIAEQLIKEVRDDETNQDEYHNLESILINVKQ
LIVNRLEQVDIGFTYDHRIIQFVGPTGVGKTTTIAKIAAKLYLEEKKKVAFITLDTYRIAAVDQLKTYAKILHIPVEVAY
SKEDYRKAVEKFSSFDVILVDTAGRNYRDNQYLNEIQEWPSSLKVTNYLVLSMTSKPKDMLDIFQRFQLLGIHGVVFTKL
DETEQYGNLLNISWNNKIRIGYMTNGQDVPEDVIQPSAEEISHLILSDNDES

Specific function: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum [H]

COG id: COG1419

COG function: function code N; Flagellar GTP-binding protein

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI226371618, Length=178, Percent_Identity=29.7752808988764, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4507215, Length=178, Percent_Identity=29.7752808988764, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1788963, Length=163, Percent_Identity=33.7423312883436, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789874, Length=184, Percent_Identity=28.2608695652174, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17539958, Length=265, Percent_Identity=27.1698113207547, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6325345, Length=180, Percent_Identity=28.3333333333333, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000897
- InterPro:   IPR020006 [H]

Pfam domain/function: PF00448 SRP54 [H]

EC number: NA

Molecular weight: Translated: 42812; Mature: 42812

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKKYTAPTMPEVMKEVRKDFGTDAVILQSKEVKKGGLLGMFKKTFIEVVAGVDPEPVN
CCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
SKSIPREKQITEYNQDNHNRKTKDENPLREEILNIQRLIEAQGRQSNHEFTPIYQLAYEH
CCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
LIAQEISPTIAEQLIKEVRDDETNQDEYHNLESILINVKQLIVNRLEQVDIGFTYDHRII
HHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCEEE
QFVGPTGVGKTTTIAKIAAKLYLEEKKKVAFITLDTYRIAAVDQLKTYAKILHIPVEVAY
EEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHEEE
SKEDYRKAVEKFSSFDVILVDTAGRNYRDNQYLNEIQEWPSSLKVTNYLVLSMTSKPKDM
CHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHEEEEEEEEEECCCCHHH
LDIFQRFQLLGIHGVVFTKLDETEQYGNLLNISWNNKIRIGYMTNGQDVPEDVIQPSAEE
HHHHHHHHHHHHCCEEEEECCCHHHHCCEEEEEECCEEEEEEECCCCCCCHHHHCCCHHH
ISHLILSDNDES
HHHHHHCCCCCC
>Mature Secondary Structure
MKIKKYTAPTMPEVMKEVRKDFGTDAVILQSKEVKKGGLLGMFKKTFIEVVAGVDPEPVN
CCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
SKSIPREKQITEYNQDNHNRKTKDENPLREEILNIQRLIEAQGRQSNHEFTPIYQLAYEH
CCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
LIAQEISPTIAEQLIKEVRDDETNQDEYHNLESILINVKQLIVNRLEQVDIGFTYDHRII
HHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCEEE
QFVGPTGVGKTTTIAKIAAKLYLEEKKKVAFITLDTYRIAAVDQLKTYAKILHIPVEVAY
EEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHEEE
SKEDYRKAVEKFSSFDVILVDTAGRNYRDNQYLNEIQEWPSSLKVTNYLVLSMTSKPKDM
CHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHEEEEEEEEEECCCCHHH
LDIFQRFQLLGIHGVVFTKLDETEQYGNLLNISWNNKIRIGYMTNGQDVPEDVIQPSAEE
HHHHHHHHHHHHCCEEEEECCCHHHHCCEEEEEECCEEEEEEECCCCCCCHHHHCCCHHH
ISHLILSDNDES
HHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1447978; 9384377 [H]