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The map label for this gene is recG [H]

Identifier: 23098975

GI number: 23098975

Start: 1563631

End: 1565661

Strand: Direct

Name: recG [H]

Synonym: OB1520

Alternate gene names: 23098975

Gene position: 1563631-1565661 (Clockwise)

Preceding gene: 23098974

Following gene: 23098976

Centisome position: 43.07

GC content: 36.58

Gene sequence:

>2031_bases
GTGATACAAAAACCTGTAACAGAAGTAAAAGGAATTGGAGAAAAAGTTGCCGAACAATTAGCGACGATGAATATTTATAC
AGTAGAGGATATGCTGGAATATTTTCCGTATCGATATGATATCTTTGAAAAAAAACCCCTACACGAATTAATCCATGATG
ATAAAGTAACTATAGAAGGGATAGTGGTCCATGACCCTTCCCTTACTTTTTATGGAAGAAAAAAATCTAGGCTTACCTTT
ACAGTAGAAGTTGATGGTGTCGCTGTTAAGGCTGTCATGTTTAATCGTTCATTTGCTAAAAAACAAATAACATCACAAAG
TTGGATTACCTTAACTGGAAAATGGGATGCGCATCGTCTGCAAATAACGGTTAGTAACTATCAGCTAGGCAGGATGGAAG
AAAAAAGTGCTATAAAACCAATTTATTCCGTTAAAGGCGATTTTACTTCCTATAAATTTCAAAAGCTTATTTCTAATACA
TTAAAAGATTCCGTAACAGAAATTAAAGAGATACTTCCTGCTACGTACTTAGATCAATATAAACTACCAAGCCGAGAGAA
TGCGGTTAAAACAATGCATTTTCCAAAAGATCGTGTGGAGTTGAAGCATGCCAGAAGGCGATTTATATATGAAGAGTTTT
TGCTTTTTCAATTAAAAATGCAACTCTTTCGTAAAAAACATAGAGAATCTACAACAGGTAATCGTCAAGATTTTGATCAA
GAGAAATTGACCTCTTTTATAAAGAGTTTTCCATTCAAATTGACAGATGCACAAAATCGAGCACTGAAGCAAATATTAAA
TGATATGAAGGATCCACATCGAATGAATCGCTTGCTTCAAGGGGATGTAGGTTCAGGGAAAACGGCTGTTGCCGCTATTT
GCTTGTATGCATCTGTAACGTCTGGACAGCAAGGGGCGTTAATGGTGCCTACAGAAATTTTAGCAGAGCAACATTTTCAA
TCTCTTCAACAAATGTTTGGAGAACGAGCTGAGATTGCTCTCTTAACAGGATCTGTAAAAGGAAAGAAAAGAAGAGAACT
GACTGAAAAAATTGAAAATCAAAAGATAGATATTGTCATAGGAACACATGCATTAATTCAAGGCGATGTGTTTTTTAAAA
ACTTAGGATTAGTTATTGTAGATGAGCAGCATCGTTTCGGTGTAGAGCAAAGACGGGTGCTACGAGACAAAGGGTTACAT
CCAGATGTGTTATTTATGACAGCGACGCCAATTCCTAGAACACTTGCAATAACAGCTTTTGGAGATATGGATGTTTCGGT
GATTGATCAACTTCCTTCAGGGCGAAAAGAAATAGAAACGTTATGGGTGAAAGCCAATACCTTTGATCGAATATTAGACT
TCGTAAGGAAGCGTGTTGATGAAGGGGAACAAGCATATGTAATAAGTCCGCTCATCGAAGAATCAGATAAACTAGATATA
CAGAATGCGGTGGAATTATATCATCAACTCGAAGCTTATTATTCTGATGATATTCGAATTGGGTTAATGCATGGGCGATT
AACTGCAAATGAAAAAGAGGACGTTATGCGTCAATTTGCAGAAAATAAAATTCAGGTGCTTGTGTCTACAACGGTAGTAG
AAGTAGGTGTGAACGTTCCAAATGCGACAATAATGATTATTTATGATGCTGAGCGTTTTGGATTATCACAATTACATCAA
TTAAGAGGAAGAGTTGGGCGCGGTGAGAAACAAAGTTATTGCATACTTATTGCCGAACCAAAGGGAGAAATCGGAAAAGA
ACGTATGCGAATTATGACAGAAACTACGGATGGATTCGAGTTGTCAGAGCAAGATTTGCAGCTGCGAGGACCAGGTGATT
TTTTTGGAAAAAAACAAAGTGGAATGCCAGAATTTAAAGTAGCGGATATGGTACATGATTATCGAGCGCTTGAAACAGCA
AGAGATGATGCATCCATCATTCTTGAAAATAATCTTTTAGAAGAGGAAGATTATCAACAAGTTCGCTCTATTCTAGAAGA
AGAAATAAATCGAATGGAAAAATTGGATTAA

Upstream 100 bases:

>100_bases
TTACGTGAAACAGGAGAAGGCGGATTAGCTGATACACCAACAGGTCGTTTATTAAAAGAGAAAATATTTGGGGTATCCGT
GTAAAGAGAGTGTGATGTAA

Downstream 100 bases:

>100_bases
TAGCCTGTCGTTTTTCGAATTCGGATCTATAAAAACAACGTGATTGTGCTTGAGATGGAGAATGGTGAATCTTCACAAGA
TAAATGAGATTATTAGATAA

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 676; Mature: 676

Protein sequence:

>676_residues
MIQKPVTEVKGIGEKVAEQLATMNIYTVEDMLEYFPYRYDIFEKKPLHELIHDDKVTIEGIVVHDPSLTFYGRKKSRLTF
TVEVDGVAVKAVMFNRSFAKKQITSQSWITLTGKWDAHRLQITVSNYQLGRMEEKSAIKPIYSVKGDFTSYKFQKLISNT
LKDSVTEIKEILPATYLDQYKLPSRENAVKTMHFPKDRVELKHARRRFIYEEFLLFQLKMQLFRKKHRESTTGNRQDFDQ
EKLTSFIKSFPFKLTDAQNRALKQILNDMKDPHRMNRLLQGDVGSGKTAVAAICLYASVTSGQQGALMVPTEILAEQHFQ
SLQQMFGERAEIALLTGSVKGKKRRELTEKIENQKIDIVIGTHALIQGDVFFKNLGLVIVDEQHRFGVEQRRVLRDKGLH
PDVLFMTATPIPRTLAITAFGDMDVSVIDQLPSGRKEIETLWVKANTFDRILDFVRKRVDEGEQAYVISPLIEESDKLDI
QNAVELYHQLEAYYSDDIRIGLMHGRLTANEKEDVMRQFAENKIQVLVSTTVVEVGVNVPNATIMIIYDAERFGLSQLHQ
LRGRVGRGEKQSYCILIAEPKGEIGKERMRIMTETTDGFELSEQDLQLRGPGDFFGKKQSGMPEFKVADMVHDYRALETA
RDDASIILENNLLEEEDYQQVRSILEEEINRMEKLD

Sequences:

>Translated_676_residues
MIQKPVTEVKGIGEKVAEQLATMNIYTVEDMLEYFPYRYDIFEKKPLHELIHDDKVTIEGIVVHDPSLTFYGRKKSRLTF
TVEVDGVAVKAVMFNRSFAKKQITSQSWITLTGKWDAHRLQITVSNYQLGRMEEKSAIKPIYSVKGDFTSYKFQKLISNT
LKDSVTEIKEILPATYLDQYKLPSRENAVKTMHFPKDRVELKHARRRFIYEEFLLFQLKMQLFRKKHRESTTGNRQDFDQ
EKLTSFIKSFPFKLTDAQNRALKQILNDMKDPHRMNRLLQGDVGSGKTAVAAICLYASVTSGQQGALMVPTEILAEQHFQ
SLQQMFGERAEIALLTGSVKGKKRRELTEKIENQKIDIVIGTHALIQGDVFFKNLGLVIVDEQHRFGVEQRRVLRDKGLH
PDVLFMTATPIPRTLAITAFGDMDVSVIDQLPSGRKEIETLWVKANTFDRILDFVRKRVDEGEQAYVISPLIEESDKLDI
QNAVELYHQLEAYYSDDIRIGLMHGRLTANEKEDVMRQFAENKIQVLVSTTVVEVGVNVPNATIMIIYDAERFGLSQLHQ
LRGRVGRGEKQSYCILIAEPKGEIGKERMRIMTETTDGFELSEQDLQLRGPGDFFGKKQSGMPEFKVADMVHDYRALETA
RDDASIILENNLLEEEDYQQVRSILEEEINRMEKLD
>Mature_676_residues
MIQKPVTEVKGIGEKVAEQLATMNIYTVEDMLEYFPYRYDIFEKKPLHELIHDDKVTIEGIVVHDPSLTFYGRKKSRLTF
TVEVDGVAVKAVMFNRSFAKKQITSQSWITLTGKWDAHRLQITVSNYQLGRMEEKSAIKPIYSVKGDFTSYKFQKLISNT
LKDSVTEIKEILPATYLDQYKLPSRENAVKTMHFPKDRVELKHARRRFIYEEFLLFQLKMQLFRKKHRESTTGNRQDFDQ
EKLTSFIKSFPFKLTDAQNRALKQILNDMKDPHRMNRLLQGDVGSGKTAVAAICLYASVTSGQQGALMVPTEILAEQHFQ
SLQQMFGERAEIALLTGSVKGKKRRELTEKIENQKIDIVIGTHALIQGDVFFKNLGLVIVDEQHRFGVEQRRVLRDKGLH
PDVLFMTATPIPRTLAITAFGDMDVSVIDQLPSGRKEIETLWVKANTFDRILDFVRKRVDEGEQAYVISPLIEESDKLDI
QNAVELYHQLEAYYSDDIRIGLMHGRLTANEKEDVMRQFAENKIQVLVSTTVVEVGVNVPNATIMIIYDAERFGLSQLHQ
LRGRVGRGEKQSYCILIAEPKGEIGKERMRIMTETTDGFELSEQDLQLRGPGDFFGKKQSGMPEFKVADMVHDYRALETA
RDDASIILENNLLEEEDYQQVRSILEEEINRMEKLD

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=664, Percent_Identity=38.5542168674699, Blast_Score=404, Evalue=1e-114,
Organism=Escherichia coli, GI1787357, Length=390, Percent_Identity=37.6923076923077, Blast_Score=255, Evalue=8e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 77751; Mature: 77751

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQKPVTEVKGIGEKVAEQLATMNIYTVEDMLEYFPYRYDIFEKKPLHELIHDDKVTIEG
CCCCCHHHHHHHHHHHHHHHHHCCEEEHHHHHHHCCCEEECCCCCCHHHHHCCCCEEEEE
IVVHDPSLTFYGRKKSRLTFTVEVDGVAVKAVMFNRSFAKKQITSQSWITLTGKWDAHRL
EEEECCCEEEEECCCCEEEEEEEECCEEEEEEHHCCHHHHHHCCCCCEEEEEECCCCEEE
QITVSNYQLGRMEEKSAIKPIYSVKGDFTSYKFQKLISNTLKDSVTEIKEILPATYLDQY
EEEEECCCCCCCCHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHC
KLPSRENAVKTMHFPKDRVELKHARRRFIYEEFLLFQLKMQLFRKKHRESTTGNRQDFDQ
CCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
EKLTSFIKSFPFKLTDAQNRALKQILNDMKDPHRMNRLLQGDVGSGKTAVAAICLYASVT
HHHHHHHHHCCCEECCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHC
SGQQGALMVPTEILAEQHFQSLQQMFGERAEIALLTGSVKGKKRRELTEKIENQKIDIVI
CCCCCEEECCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEE
GTHALIQGDVFFKNLGLVIVDEQHRFGVEQRRVLRDKGLHPDVLFMTATPIPRTLAITAF
ECHHHEECCEEEECCCEEEEECHHHCCHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEEE
GDMDVSVIDQLPSGRKEIETLWVKANTFDRILDFVRKRVDEGEQAYVISPLIEESDKLDI
CCCCHHHHHCCCCCCHHEEEEEEECCCHHHHHHHHHHHHCCCCCEEEECHHHCCCCCCCH
QNAVELYHQLEAYYSDDIRIGLMHGRLTANEKEDVMRQFAENKIQVLVSTTVVEVGVNVP
HHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHCCCEEEEEEEEEEEECCCCC
NATIMIIYDAERFGLSQLHQLRGRVGRGEKQSYCILIAEPKGEIGKERMRIMTETTDGFE
CEEEEEEECCHHCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHEECCCCCC
LSEQDLQLRGPGDFFGKKQSGMPEFKVADMVHDYRALETARDDASIILENNLLEEEDYQQ
CCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHH
VRSILEEEINRMEKLD
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIQKPVTEVKGIGEKVAEQLATMNIYTVEDMLEYFPYRYDIFEKKPLHELIHDDKVTIEG
CCCCCHHHHHHHHHHHHHHHHHCCEEEHHHHHHHCCCEEECCCCCCHHHHHCCCCEEEEE
IVVHDPSLTFYGRKKSRLTFTVEVDGVAVKAVMFNRSFAKKQITSQSWITLTGKWDAHRL
EEEECCCEEEEECCCCEEEEEEEECCEEEEEEHHCCHHHHHHCCCCCEEEEEECCCCEEE
QITVSNYQLGRMEEKSAIKPIYSVKGDFTSYKFQKLISNTLKDSVTEIKEILPATYLDQY
EEEEECCCCCCCCHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHC
KLPSRENAVKTMHFPKDRVELKHARRRFIYEEFLLFQLKMQLFRKKHRESTTGNRQDFDQ
CCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
EKLTSFIKSFPFKLTDAQNRALKQILNDMKDPHRMNRLLQGDVGSGKTAVAAICLYASVT
HHHHHHHHHCCCEECCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHC
SGQQGALMVPTEILAEQHFQSLQQMFGERAEIALLTGSVKGKKRRELTEKIENQKIDIVI
CCCCCEEECCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEE
GTHALIQGDVFFKNLGLVIVDEQHRFGVEQRRVLRDKGLHPDVLFMTATPIPRTLAITAF
ECHHHEECCEEEECCCEEEEECHHHCCHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEEE
GDMDVSVIDQLPSGRKEIETLWVKANTFDRILDFVRKRVDEGEQAYVISPLIEESDKLDI
CCCCHHHHHCCCCCCHHEEEEEEECCCHHHHHHHHHHHHCCCCCEEEECHHHCCCCCCCH
QNAVELYHQLEAYYSDDIRIGLMHGRLTANEKEDVMRQFAENKIQVLVSTTVVEVGVNVP
HHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHCCCEEEEEEEEEEEECCCCC
NATIMIIYDAERFGLSQLHQLRGRVGRGEKQSYCILIAEPKGEIGKERMRIMTETTDGFE
CEEEEEEECCHHCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHEECCCCCC
LSEQDLQLRGPGDFFGKKQSGMPEFKVADMVHDYRALETARDDASIILENNLLEEEDYQQ
CCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHH
VRSILEEEINRMEKLD
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]