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The map label for this gene is sdaAA [H]

Identifier: 23098974

GI number: 23098974

Start: 1562739

End: 1563614

Strand: Direct

Name: sdaAA [H]

Synonym: OB1519

Alternate gene names: 23098974

Gene position: 1562739-1563614 (Clockwise)

Preceding gene: 23098973

Following gene: 23098975

Centisome position: 43.04

GC content: 40.64

Gene sequence:

>876_bases
ATGTTTCGTACAGTTAAAGAGTTAGTTGACACAGCAAATGAAAAACAAATACCGATATCTGAAGTAATGATTTTGCAAGA
AATGGAAGTAAAAGAACAGTCTCGAGAGCAAGTGATGGCTGAAATGGAAAAGAATCTCCAGGTGATGGGAAACGCAATTG
AAGATGCTTTAAAAGGTGTAGAATCTGTGACAGGATTAACTGGTGGAGATGCGGTTAAAGTGCAAAAATATATGAAAGAA
AAAACACCTTTATCTGGAAATTTAATGATGGATGCGGTAAGTAAGGCAATGGGTACCAATGAAGTGAATGCAGCAATGGG
AATCATTTGCGCAACACCAACAGCAGGTAGTGCAGGATGCGTGCCAGGGACATTATTTGCCGTGAAAGAGCAGCTTAATC
CGAGTCGGGAACAAATGATTCGCTACCTATTTACTTCTGGAGCATTTGGTTTTGTAGTTGCAAATAATGCGTTTATTTCA
GGTGCAGCTGGTGGTTGTCAAGCGGAAGTAGGATCAGCAGGAGCGATGGCATCTGCTGCTATTGTGGAAATGGCAGGAGG
TACACCAGAACAATCTTCACATGCATTTGCAATGACTTTAAAAAATATGCTTGGATTAGTATGTGATCCAGTAGCTGGTT
TAGTAGAGGTACCTTGCGTAAAACGCAATGCTGGCGGATCCTCTTTAGCAATAGTATCTGCAGATTTAGCATTAGCTGGT
GTAGAAAGTAGAATTCCTTGTGATGAAGTTATTGGAGCGATGTACCGTATTGGAAAACAAATGCCATCTAGTTTACGTGA
AACAGGAGAAGGCGGATTAGCTGATACACCAACAGGTCGTTTATTAAAAGAGAAAATATTTGGGGTATCCGTGTAA

Upstream 100 bases:

>100_bases
GATGAAATACTAAATGAATTAAATGCAGCAGATCATATCATTTCCATCTCAAAAATTGTAAGTTAAAGTGGTTTGATGTA
TCTCAAAGGAGGGTTTAACG

Downstream 100 bases:

>100_bases
AGAGAGTGTGATGTAAGTGATACAAAAACCTGTAACAGAAGTAAAAGGAATTGGAGAAAAAGTTGCCGAACAATTAGCGA
CGATGAATATTTATACAGTA

Product: L-serine dehydratase alpha subunit

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MFRTVKELVDTANEKQIPISEVMILQEMEVKEQSREQVMAEMEKNLQVMGNAIEDALKGVESVTGLTGGDAVKVQKYMKE
KTPLSGNLMMDAVSKAMGTNEVNAAMGIICATPTAGSAGCVPGTLFAVKEQLNPSREQMIRYLFTSGAFGFVVANNAFIS
GAAGGCQAEVGSAGAMASAAIVEMAGGTPEQSSHAFAMTLKNMLGLVCDPVAGLVEVPCVKRNAGGSSLAIVSADLALAG
VESRIPCDEVIGAMYRIGKQMPSSLRETGEGGLADTPTGRLLKEKIFGVSV

Sequences:

>Translated_291_residues
MFRTVKELVDTANEKQIPISEVMILQEMEVKEQSREQVMAEMEKNLQVMGNAIEDALKGVESVTGLTGGDAVKVQKYMKE
KTPLSGNLMMDAVSKAMGTNEVNAAMGIICATPTAGSAGCVPGTLFAVKEQLNPSREQMIRYLFTSGAFGFVVANNAFIS
GAAGGCQAEVGSAGAMASAAIVEMAGGTPEQSSHAFAMTLKNMLGLVCDPVAGLVEVPCVKRNAGGSSLAIVSADLALAG
VESRIPCDEVIGAMYRIGKQMPSSLRETGEGGLADTPTGRLLKEKIFGVSV
>Mature_291_residues
MFRTVKELVDTANEKQIPISEVMILQEMEVKEQSREQVMAEMEKNLQVMGNAIEDALKGVESVTGLTGGDAVKVQKYMKE
KTPLSGNLMMDAVSKAMGTNEVNAAMGIICATPTAGSAGCVPGTLFAVKEQLNPSREQMIRYLFTSGAFGFVVANNAFIS
GAAGGCQAEVGSAGAMASAAIVEMAGGTPEQSSHAFAMTLKNMLGLVCDPVAGLVEVPCVKRNAGGSSLAIVSADLALAG
VESRIPCDEVIGAMYRIGKQMPSSLRETGEGGLADTPTGRLLKEKIFGVSV

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI48994925, Length=283, Percent_Identity=34.2756183745583, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1788116, Length=283, Percent_Identity=35.6890459363958, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1789161, Length=283, Percent_Identity=33.5689045936396, Blast_Score=134, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005130
- InterPro:   IPR004642 [H]

Pfam domain/function: PF03313 SDH_alpha [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 30320; Mature: 30320

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
6.2 %Met     (Translated Protein)
8.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
6.2 %Met     (Mature Protein)
8.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRTVKELVDTANEKQIPISEVMILQEMEVKEQSREQVMAEMEKNLQVMGNAIEDALKGV
CCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESVTGLTGGDAVKVQKYMKEKTPLSGNLMMDAVSKAMGTNEVNAAMGIICATPTAGSAGC
HHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHEEEEECCCCCCCCC
VPGTLFAVKEQLNPSREQMIRYLFTSGAFGFVVANNAFISGAAGGCQAEVGSAGAMASAA
CCHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEECCCEEECCCCCCCCCCCCCHHHHHHH
IVEMAGGTPEQSSHAFAMTLKNMLGLVCDPVAGLVEVPCVKRNAGGSSLAIVSADLALAG
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHC
VESRIPCDEVIGAMYRIGKQMPSSLRETGEGGLADTPTGRLLKEKIFGVSV
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MFRTVKELVDTANEKQIPISEVMILQEMEVKEQSREQVMAEMEKNLQVMGNAIEDALKGV
CCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESVTGLTGGDAVKVQKYMKEKTPLSGNLMMDAVSKAMGTNEVNAAMGIICATPTAGSAGC
HHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHEEEEECCCCCCCCC
VPGTLFAVKEQLNPSREQMIRYLFTSGAFGFVVANNAFISGAAGGCQAEVGSAGAMASAA
CCHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEECCCEEECCCCCCCCCCCCCHHHHHHH
IVEMAGGTPEQSSHAFAMTLKNMLGLVCDPVAGLVEVPCVKRNAGGSSLAIVSADLALAG
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHC
VESRIPCDEVIGAMYRIGKQMPSSLRETGEGGLADTPTGRLLKEKIFGVSV
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]