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The map label for this gene is patA [H]

Identifier: 23098846

GI number: 23098846

Start: 1435652

End: 1436803

Strand: Reverse

Name: patA [H]

Synonym: OB1391

Alternate gene names: 23098846

Gene position: 1436803-1435652 (Counterclockwise)

Preceding gene: 23098848

Following gene: 23098845

Centisome position: 39.58

GC content: 34.38

Gene sequence:

>1152_bases
ATGGAACATTTATTAAATCAGCAAGTACAAAACATTGAAATATCAGGAATTCGAAAGTTTTTTAATCTCGTTTCTAACGA
AAAAGATATTGTTTCGTTAACCATTGGTCAACCTGACTTTTATACTCCACATGCAATAAAACAAGCTTCCATAAATGCGG
TTAATAATAATCATACAACTTACACCGCAAATGCTGGTGTAATAGAGTTACGTAAAGCTATTGCTAACTACTATGAATCT
CGATATCAGATTCCATATCATCCAGAATCAGAAATTATCGTAACTGCAGGAGCTTCAGAGGCTATTGATATTACCCTCCG
TACAATTTTAGAGCCTGGTGATGAAGTGATCTTACCAGCACCAATTTACCCTGGGTATGAACCATTAATTACACTAGCAC
GTGCCAAACCTATACATATGGACACAACAAAGACCAATTTCAAAATAACTAAGTCTCAACTAGAAGAGACCATTACAGAG
AAGACAAAATGTATAATTATCCCTTCTCCTTCCAACCCAACTGGTGCAGCTTATACGAAGAAGGAGCTTGATGAAATTGT
TTCTGTATTAAAAGATAAAAAACTATTTATACTGTCTGATGAAATTTATAGTGAAATTATCTTTGATCAACCTCATGTAT
CTATAGCATCGTATCCTGAGATGAGAGATCAAACAATTGTAATTAATGGTTTGTCAAAGTCTCATTCCATGACCGGCTTT
CGTATTGGATATGCGCTAGCCCCTCATTGGTTGTCTAAACATATGTTAAAAGTTCATCAATACAATGTTTCTTGTGCTTC
TTCTATAAGTCAATATGCTGCACTAGAAGCTTTTAATTCTAACGATGATCATTTGCAACTGATAAAAGATACGTATAAAA
GTAGAAGAGATTTAGTTTACAACCGCCTTACATCAATGGGAATCGATGTTCAACTACCAGAAGGAGCGTTTTACATGTTT
CCTCGTTTTCCAATGAGAAACGAAAACTCATTTGAATTCGGATTGACATTAGTAAAACAAGCAAAAGTAGCACTTGTACC
TGGTAATAGTTTTTCACAATATGGAGAAGGATTTATGAGGTTATCTTACGCCTACCATGAAGATGTATTAAATAAAGGAC
TAGATCGAATAGAAAAGTTTCTAAACCAGTAA

Upstream 100 bases:

>100_bases
CTGTTATTATTATTATACCCGAAAAATATATTATAAATCTAAATTATTTGAACATTTTATTAAAATTTTCCTCAATTATG
AAAAAGGCATGGTGAAATAC

Downstream 100 bases:

>100_bases
AAATATTGAGAAATTTTTAGATAATTAATCTCGAAATATAATATAAATTATGCTACGATTAGTATAACCTTTTATCATCG
GAGGATGGTCCATTGTGACT

Product: aminotransferase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MEHLLNQQVQNIEISGIRKFFNLVSNEKDIVSLTIGQPDFYTPHAIKQASINAVNNNHTTYTANAGVIELRKAIANYYES
RYQIPYHPESEIIVTAGASEAIDITLRTILEPGDEVILPAPIYPGYEPLITLARAKPIHMDTTKTNFKITKSQLEETITE
KTKCIIIPSPSNPTGAAYTKKELDEIVSVLKDKKLFILSDEIYSEIIFDQPHVSIASYPEMRDQTIVINGLSKSHSMTGF
RIGYALAPHWLSKHMLKVHQYNVSCASSISQYAALEAFNSNDDHLQLIKDTYKSRRDLVYNRLTSMGIDVQLPEGAFYMF
PRFPMRNENSFEFGLTLVKQAKVALVPGNSFSQYGEGFMRLSYAYHEDVLNKGLDRIEKFLNQ

Sequences:

>Translated_383_residues
MEHLLNQQVQNIEISGIRKFFNLVSNEKDIVSLTIGQPDFYTPHAIKQASINAVNNNHTTYTANAGVIELRKAIANYYES
RYQIPYHPESEIIVTAGASEAIDITLRTILEPGDEVILPAPIYPGYEPLITLARAKPIHMDTTKTNFKITKSQLEETITE
KTKCIIIPSPSNPTGAAYTKKELDEIVSVLKDKKLFILSDEIYSEIIFDQPHVSIASYPEMRDQTIVINGLSKSHSMTGF
RIGYALAPHWLSKHMLKVHQYNVSCASSISQYAALEAFNSNDDHLQLIKDTYKSRRDLVYNRLTSMGIDVQLPEGAFYMF
PRFPMRNENSFEFGLTLVKQAKVALVPGNSFSQYGEGFMRLSYAYHEDVLNKGLDRIEKFLNQ
>Mature_383_residues
MEHLLNQQVQNIEISGIRKFFNLVSNEKDIVSLTIGQPDFYTPHAIKQASINAVNNNHTTYTANAGVIELRKAIANYYES
RYQIPYHPESEIIVTAGASEAIDITLRTILEPGDEVILPAPIYPGYEPLITLARAKPIHMDTTKTNFKITKSQLEETITE
KTKCIIIPSPSNPTGAAYTKKELDEIVSVLKDKKLFILSDEIYSEIIFDQPHVSIASYPEMRDQTIVINGLSKSHSMTGF
RIGYALAPHWLSKHMLKVHQYNVSCASSISQYAALEAFNSNDDHLQLIKDTYKSRRDLVYNRLTSMGIDVQLPEGAFYMF
PRFPMRNENSFEFGLTLVKQAKVALVPGNSFSQYGEGFMRLSYAYHEDVLNKGLDRIEKFLNQ

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=400, Percent_Identity=27, Blast_Score=156, Evalue=4e-38,
Organism=Homo sapiens, GI56713256, Length=399, Percent_Identity=26.5664160401003, Blast_Score=156, Evalue=4e-38,
Organism=Homo sapiens, GI95147551, Length=341, Percent_Identity=26.6862170087977, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI169881279, Length=341, Percent_Identity=26.6862170087977, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI4507369, Length=383, Percent_Identity=26.6318537859008, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI169881281, Length=223, Percent_Identity=26.0089686098655, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI149944424, Length=295, Percent_Identity=25.4237288135593, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI187936925, Length=378, Percent_Identity=23.5449735449735, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI14211921, Length=378, Percent_Identity=23.5449735449735, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI215599424, Length=350, Percent_Identity=23.7142857142857, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI19263340, Length=350, Percent_Identity=23.7142857142857, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI1786816, Length=361, Percent_Identity=26.3157894736842, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1788722, Length=364, Percent_Identity=28.5714285714286, Blast_Score=165, Evalue=5e-42,
Organism=Escherichia coli, GI1788627, Length=374, Percent_Identity=29.4117647058824, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI1787710, Length=306, Percent_Identity=25.4901960784314, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787909, Length=356, Percent_Identity=20.5056179775281, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1788332, Length=174, Percent_Identity=25.8620689655172, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71994476, Length=401, Percent_Identity=25.4364089775561, Blast_Score=135, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI71994472, Length=401, Percent_Identity=25.4364089775561, Blast_Score=135, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI17567369, Length=401, Percent_Identity=25.6857855361596, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17567663, Length=373, Percent_Identity=22.7882037533512, Blast_Score=110, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI71981209, Length=345, Percent_Identity=25.2173913043478, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71981215, Length=164, Percent_Identity=27.4390243902439, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322401, Length=378, Percent_Identity=24.8677248677249, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6323118, Length=432, Percent_Identity=24.3055555555556, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320317, Length=367, Percent_Identity=23.9782016348774, Blast_Score=80, Evalue=8e-16,
Organism=Drosophila melanogaster, GI28573069, Length=386, Percent_Identity=25.1295336787565, Blast_Score=148, Evalue=7e-36,
Organism=Drosophila melanogaster, GI24646114, Length=386, Percent_Identity=25.1295336787565, Blast_Score=148, Evalue=7e-36,
Organism=Drosophila melanogaster, GI28573067, Length=386, Percent_Identity=25.1295336787565, Blast_Score=148, Evalue=7e-36,
Organism=Drosophila melanogaster, GI28573065, Length=386, Percent_Identity=25.1295336787565, Blast_Score=148, Evalue=7e-36,
Organism=Drosophila melanogaster, GI18859735, Length=382, Percent_Identity=24.6073298429319, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI45551451, Length=369, Percent_Identity=25.7452574525745, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24641770, Length=369, Percent_Identity=26.0162601626016, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24641760, Length=369, Percent_Identity=26.0162601626016, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24641768, Length=369, Percent_Identity=26.0162601626016, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24641766, Length=369, Percent_Identity=26.0162601626016, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24641764, Length=369, Percent_Identity=26.0162601626016, Blast_Score=83, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 43382; Mature: 43382

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHLLNQQVQNIEISGIRKFFNLVSNEKDIVSLTIGQPDFYTPHAIKQASINAVNNNHTT
CCHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHCEEECCCCEE
YTANAGVIELRKAIANYYESRYQIPYHPESEIIVTAGASEAIDITLRTILEPGDEVILPA
EEECCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCEEEEEHHHCCCCCEEECC
PIYPGYEPLITLARAKPIHMDTTKTNFKITKSQLEETITEKTKCIIIPSPSNPTGAAYTK
CCCCCHHHHHHHHCCCCEEECCCCCCEEEEHHHHHHHHHCCCEEEEEECCCCCCCCCHHH
KELDEIVSVLKDKKLFILSDEIYSEIIFDQPHVSIASYPEMRDQTIVINGLSKSHSMTGF
HHHHHHHHHHCCCEEEEEEHHHHHHHHCCCCCCEECCCCCCCCCEEEEECCCCCCCCCEE
RIGYALAPHWLSKHMLKVHQYNVSCASSISQYAALEAFNSNDDHLQLIKDTYKSRRDLVY
EEHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
NRLTSMGIDVQLPEGAFYMFPRFPMRNENSFEFGLTLVKQAKVALVPGNSFSQYGEGFMR
HHHHHCCCEEECCCCCEEECCCCCCCCCCCHHHHHHEEECCEEEEECCCCHHHHCCHHEE
LSYAYHEDVLNKGLDRIEKFLNQ
HHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEHLLNQQVQNIEISGIRKFFNLVSNEKDIVSLTIGQPDFYTPHAIKQASINAVNNNHTT
CCHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHCEEECCCCEE
YTANAGVIELRKAIANYYESRYQIPYHPESEIIVTAGASEAIDITLRTILEPGDEVILPA
EEECCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCEEEEEHHHCCCCCEEECC
PIYPGYEPLITLARAKPIHMDTTKTNFKITKSQLEETITEKTKCIIIPSPSNPTGAAYTK
CCCCCHHHHHHHHCCCCEEECCCCCCEEEEHHHHHHHHHCCCEEEEEECCCCCCCCCHHH
KELDEIVSVLKDKKLFILSDEIYSEIIFDQPHVSIASYPEMRDQTIVINGLSKSHSMTGF
HHHHHHHHHHCCCEEEEEEHHHHHHHHCCCCCCEECCCCCCCCCEEEEECCCCCCCCCEE
RIGYALAPHWLSKHMLKVHQYNVSCASSISQYAALEAFNSNDDHLQLIKDTYKSRRDLVY
EEHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
NRLTSMGIDVQLPEGAFYMFPRFPMRNENSFEFGLTLVKQAKVALVPGNSFSQYGEGFMR
HHHHHCCCEEECCCCCEEECCCCCCCCCCCHHHHHHEEECCEEEEECCCCHHHHCCHHEE
LSYAYHEDVLNKGLDRIEKFLNQ
HHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2104615 [H]