The gene/protein map for NC_004193 is currently unavailable.
Definition Oceanobacillus iheyensis HTE831, complete genome.
Accession NC_004193
Length 3,630,528

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The map label for this gene is ppiB [H]

Identifier: 23098815

GI number: 23098815

Start: 1407965

End: 1408573

Strand: Reverse

Name: ppiB [H]

Synonym: OB1360

Alternate gene names: 23098815

Gene position: 1408573-1407965 (Counterclockwise)

Preceding gene: 23098816

Following gene: 23098814

Centisome position: 38.8

GC content: 38.26

Gene sequence:

>609_bases
ATGAAGCAAAGATATCTATTTATACTAATGCTAATGATAACTCTTCTTTTATCAGCATGCGCTGATACCGAAGAAACACC
GAGCGAAGAAACTCAATCGGAGGATAATCCGATAGCTACTATTACGATGGATAATAAACAAACTATTACTGTGGAACTTT
ATCCTGAAATTGCTCCTAACACAGTAACTAATTTTATTTCTCTAATTGAAGATGGCTTTTATGATGGATTAACTTTCCAC
CGGATTGTCCCCGAATTTGTTATCCAAGGTGGCGATCCTGAAGGAAATGGAACTGGAGGACCCGGATATTCTATCCCAGG
AGAATTCACTTCGAATGGATTTGAAAATGATTTAATCCACGAACGTGGTGTCCTTTCAATGGCTAGAAGTCAACATCCTG
ATTCGGCAGGATCTCAATTTTTTATTGTTTTAGACAAAGCCGACCATCTTGATAAAGATTATGCAGGGTTCGGAAAAGTC
ATTGAAGGCATGGAAACGGTAGATAACATTGTGGAACAAGGAACTTCTGGACAAGAAGTTCCAACCATTAAGGAAATAAC
TGTAGATACCAAAGGACAAGACTACGGAGAGCCAGAAAAAACAGAATAA

Upstream 100 bases:

>100_bases
TTAGCGTCTTCTTCACACATTTCACTTCTCTGTCTAAGGAGGTGAAATCGAAGTTTTATGGACAAGTCCTCACCGTGATT
AAAAACAAAGGAGAACTAAA

Downstream 100 bases:

>100_bases
CCAAATAGACTTGTTGATAATGGTAATAGAGAGTATTTAATAGGATCTCTAGAAGCAGGATGCTGTGCTAACTAATATGA
TCTTTCCATGGACATCGATT

Product: peptidyl-prolyl cis-trans isomerase B

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MKQRYLFILMLMITLLLSACADTEETPSEETQSEDNPIATITMDNKQTITVELYPEIAPNTVTNFISLIEDGFYDGLTFH
RIVPEFVIQGGDPEGNGTGGPGYSIPGEFTSNGFENDLIHERGVLSMARSQHPDSAGSQFFIVLDKADHLDKDYAGFGKV
IEGMETVDNIVEQGTSGQEVPTIKEITVDTKGQDYGEPEKTE

Sequences:

>Translated_202_residues
MKQRYLFILMLMITLLLSACADTEETPSEETQSEDNPIATITMDNKQTITVELYPEIAPNTVTNFISLIEDGFYDGLTFH
RIVPEFVIQGGDPEGNGTGGPGYSIPGEFTSNGFENDLIHERGVLSMARSQHPDSAGSQFFIVLDKADHLDKDYAGFGKV
IEGMETVDNIVEQGTSGQEVPTIKEITVDTKGQDYGEPEKTE
>Mature_202_residues
MKQRYLFILMLMITLLLSACADTEETPSEETQSEDNPIATITMDNKQTITVELYPEIAPNTVTNFISLIEDGFYDGLTFH
RIVPEFVIQGGDPEGNGTGGPGYSIPGEFTSNGFENDLIHERGVLSMARSQHPDSAGSQFFIVLDKADHLDKDYAGFGKV
IEGMETVDNIVEQGTSGQEVPTIKEITVDTKGQDYGEPEKTE

Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]

COG id: COG0652

COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase cyclophilin-type domain [H]

Homologues:

Organism=Homo sapiens, GI19557636, Length=123, Percent_Identity=43.9024390243902, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI7706339, Length=135, Percent_Identity=40.7407407407407, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI64276486, Length=113, Percent_Identity=43.3628318584071, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI4505991, Length=139, Percent_Identity=43.8848920863309, Blast_Score=89, Evalue=2e-18,
Organism=Homo sapiens, GI24308049, Length=158, Percent_Identity=39.873417721519, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI5174637, Length=183, Percent_Identity=38.2513661202186, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI10863927, Length=151, Percent_Identity=41.7218543046358, Blast_Score=85, Evalue=4e-17,
Organism=Homo sapiens, GI5031987, Length=168, Percent_Identity=39.8809523809524, Blast_Score=84, Evalue=8e-17,
Organism=Homo sapiens, GI45439316, Length=166, Percent_Identity=39.1566265060241, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI303305009, Length=196, Percent_Identity=35.7142857142857, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI150418007, Length=176, Percent_Identity=39.2045454545455, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI4758950, Length=181, Percent_Identity=35.3591160220994, Blast_Score=80, Evalue=9e-16,
Organism=Homo sapiens, GI22547212, Length=124, Percent_Identity=44.3548387096774, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI7657473, Length=124, Percent_Identity=44.3548387096774, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI22547215, Length=124, Percent_Identity=44.3548387096774, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI256017253, Length=162, Percent_Identity=39.5061728395062, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI221139811, Length=162, Percent_Identity=39.5061728395062, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI256017251, Length=162, Percent_Identity=39.5061728395062, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI209417936, Length=162, Percent_Identity=38.8888888888889, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI30102944, Length=162, Percent_Identity=38.8888888888889, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI219842199, Length=162, Percent_Identity=38.8888888888889, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI6631100, Length=148, Percent_Identity=41.2162162162162, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI178057341, Length=162, Percent_Identity=38.8888888888889, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI5454154, Length=148, Percent_Identity=35.1351351351351, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI4826932, Length=167, Percent_Identity=35.9281437125749, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI169163387, Length=152, Percent_Identity=38.1578947368421, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI310129267, Length=145, Percent_Identity=39.3103448275862, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI310120620, Length=145, Percent_Identity=39.3103448275862, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI310127646, Length=152, Percent_Identity=38.1578947368421, Blast_Score=72, Evalue=2e-13,
Organism=Homo sapiens, GI310114371, Length=152, Percent_Identity=38.1578947368421, Blast_Score=72, Evalue=2e-13,
Organism=Homo sapiens, GI310119221, Length=152, Percent_Identity=38.1578947368421, Blast_Score=72, Evalue=2e-13,
Organism=Homo sapiens, GI42560244, Length=148, Percent_Identity=36.4864864864865, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI310110104, Length=133, Percent_Identity=42.1052631578947, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI169164185, Length=152, Percent_Identity=37.5, Blast_Score=71, Evalue=6e-13,
Organism=Homo sapiens, GI169163623, Length=152, Percent_Identity=37.5, Blast_Score=71, Evalue=6e-13,
Organism=Homo sapiens, GI20911035, Length=142, Percent_Identity=32.3943661971831, Blast_Score=68, Evalue=7e-12,
Organism=Escherichia coli, GI1789763, Length=152, Percent_Identity=39.4736842105263, Blast_Score=89, Evalue=1e-19,
Organism=Escherichia coli, GI1786736, Length=162, Percent_Identity=37.037037037037, Blast_Score=84, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17539496, Length=137, Percent_Identity=42.3357664233577, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17506311, Length=147, Percent_Identity=40.1360544217687, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71980590, Length=138, Percent_Identity=39.8550724637681, Blast_Score=96, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI71980594, Length=138, Percent_Identity=39.8550724637681, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17532641, Length=139, Percent_Identity=37.410071942446, Blast_Score=90, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17552782, Length=152, Percent_Identity=42.1052631578947, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17566266, Length=153, Percent_Identity=41.8300653594771, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17559074, Length=170, Percent_Identity=37.6470588235294, Blast_Score=86, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17539498, Length=143, Percent_Identity=43.3566433566434, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17532643, Length=177, Percent_Identity=35.5932203389831, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17551284, Length=152, Percent_Identity=40.1315789473684, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17551282, Length=152, Percent_Identity=40.1315789473684, Blast_Score=81, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71997782, Length=115, Percent_Identity=40.8695652173913, Blast_Score=81, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17565860, Length=149, Percent_Identity=40.9395973154362, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17552780, Length=128, Percent_Identity=43.75, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17506307, Length=129, Percent_Identity=44.1860465116279, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17552784, Length=150, Percent_Identity=38.6666666666667, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32563659, Length=147, Percent_Identity=31.2925170068027, Blast_Score=67, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6320359, Length=132, Percent_Identity=40.1515151515151, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6323562, Length=134, Percent_Identity=42.5373134328358, Blast_Score=79, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6321848, Length=130, Percent_Identity=42.3076923076923, Blast_Score=77, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320510, Length=203, Percent_Identity=32.512315270936, Blast_Score=72, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6323246, Length=171, Percent_Identity=32.7485380116959, Blast_Score=71, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17986117, Length=123, Percent_Identity=49.5934959349593, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI19922376, Length=123, Percent_Identity=40.650406504065, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI45549139, Length=160, Percent_Identity=41.25, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24664125, Length=150, Percent_Identity=41.3333333333333, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI21357783, Length=150, Percent_Identity=41.3333333333333, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI17647301, Length=170, Percent_Identity=38.8235294117647, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24652460, Length=123, Percent_Identity=34.9593495934959, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21357249, Length=113, Percent_Identity=38.9380530973451, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24650807, Length=131, Percent_Identity=39.6946564885496, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI20130249, Length=150, Percent_Identity=39.3333333333333, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI17136360, Length=170, Percent_Identity=34.7058823529412, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24586038, Length=180, Percent_Identity=32.7777777777778, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI19922912, Length=127, Percent_Identity=40.9448818897638, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015891
- InterPro:   IPR020892
- InterPro:   IPR002130 [H]

Pfam domain/function: PF00160 Pro_isomerase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 22204; Mature: 22204

Theoretical pI: Translated: 3.93; Mature: 3.93

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00170 CSA_PPIASE_1 ; PS50072 CSA_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MKQRYLFILMLMITLLLSACADTEETPSEETQSEDNPIATITMDNKQTITVELYPEIAPN
CCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCEEEEEECCCEEEEEEECCCCCCH
TVTNFISLIEDGFYDGLTFHRIVPEFVIQGGDPEGNGTGGPGYSIPGEFTSNGFENDLIH
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
ERGVLSMARSQHPDSAGSQFFIVLDKADHLDKDYAGFGKVIEGMETVDNIVEQGTSGQEV
HHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PTIKEITVDTKGQDYGEPEKTE
CCEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MKQRYLFILMLMITLLLSACADTEETPSEETQSEDNPIATITMDNKQTITVELYPEIAPN
CCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCEEEEEECCCEEEEEEECCCCCCH
TVTNFISLIEDGFYDGLTFHRIVPEFVIQGGDPEGNGTGGPGYSIPGEFTSNGFENDLIH
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
ERGVLSMARSQHPDSAGSQFFIVLDKADHLDKDYAGFGKVIEGMETVDNIVEQGTSGQEV
HHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PTIKEITVDTKGQDYGEPEKTE
CCEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9317025; 9665876 [H]