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The map label for this gene is uppP

Identifier: 23098654

GI number: 23098654

Start: 1249813

End: 1250640

Strand: Reverse

Name: uppP

Synonym: OB1199

Alternate gene names: 23098654

Gene position: 1250640-1249813 (Counterclockwise)

Preceding gene: 23098656

Following gene: 23098653

Centisome position: 34.45

GC content: 34.9

Gene sequence:

>828_bases
ATGAATGTGTTTGAAAATTTTTGGACAATCGTGCATTATTTTGTTCTTGGACTTGTACAAGGTATCACGGAGCCAATCCC
TATCTCTTCTAGTGGGCATATAATTATATTTCGAGAACTATTTGGAATTGAAGCGAGAGGTTTATCATTTGAGATATTTG
TAAACTTAGCTTCTTTACTTGCCGTATTAATAATCTATCGTAAAGACATAGTCCGATTGGCAGTAAATAGTTGGAACTTT
ATATTCAAGCAAGAAAAAGAATCTAAAAGTGATTTTATGTTTGTCGTTTATCTTGTCCTTGCTACTATCCCAGTTGGAAT
CGTCGGTGTACTATTTGGTGATGAGATTGGAGCATTTATTGGCGAAGATGGTACAACTGTAGTTGGAATCACACTACTAA
TAACTGCTGCAGCGATTTGGATGATTCGTAACTTACGCGGTAGAAAGATCGAAGGAGATTTATCTACAAAAGATGCTGTT
ATTGTAGGACTAGCACAAGCTGTTGCCGTTACACCTGGTATAAGTAGATCAGGGGCTACATTAGTAGCATCTATGTTAAT
GGGAATGAAGCAAGATACCGCATTACGATTTTCATTCCTTTTATATATTCCGGTTAGTTTAGGGTCTTCCATATTAGAAA
TACCAAATATTGTACGCGATCCAAATGTTCAGGAATTATGGATACCATATTTAGTTGCTTTTATTACAGCATTTATTGCT
TCTTATTTTGCATTAAAATGGTTTATGAATATAATGCGACATGGAAACCTTAAATATTTTGCATACTACTGTGTAATTGT
CGGAGTGCTCGTATTAATATTCCTATAG

Upstream 100 bases:

>100_bases
TTGTTTTATCAGTCATTTTTTATCCTCCTCCATGATAGCCTATGCATCTATATTTGGAGTGGTGAAAATAACCCAGAAAT
TGAATGAAGGAGTTAAAATC

Downstream 100 bases:

>100_bases
AACTTATTTAAGATCTCAAAACAAGTACCTTAAACTTGTTTTGAGGTCTTTTTCGTATGGGTAGAAAAATTTATTTAAAC
AGGCTTAATTCGGTTACCAA

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MNVFENFWTIVHYFVLGLVQGITEPIPISSSGHIIIFRELFGIEARGLSFEIFVNLASLLAVLIIYRKDIVRLAVNSWNF
IFKQEKESKSDFMFVVYLVLATIPVGIVGVLFGDEIGAFIGEDGTTVVGITLLITAAAIWMIRNLRGRKIEGDLSTKDAV
IVGLAQAVAVTPGISRSGATLVASMLMGMKQDTALRFSFLLYIPVSLGSSILEIPNIVRDPNVQELWIPYLVAFITAFIA
SYFALKWFMNIMRHGNLKYFAYYCVIVGVLVLIFL

Sequences:

>Translated_275_residues
MNVFENFWTIVHYFVLGLVQGITEPIPISSSGHIIIFRELFGIEARGLSFEIFVNLASLLAVLIIYRKDIVRLAVNSWNF
IFKQEKESKSDFMFVVYLVLATIPVGIVGVLFGDEIGAFIGEDGTTVVGITLLITAAAIWMIRNLRGRKIEGDLSTKDAV
IVGLAQAVAVTPGISRSGATLVASMLMGMKQDTALRFSFLLYIPVSLGSSILEIPNIVRDPNVQELWIPYLVAFITAFIA
SYFALKWFMNIMRHGNLKYFAYYCVIVGVLVLIFL
>Mature_275_residues
MNVFENFWTIVHYFVLGLVQGITEPIPISSSGHIIIFRELFGIEARGLSFEIFVNLASLLAVLIIYRKDIVRLAVNSWNF
IFKQEKESKSDFMFVVYLVLATIPVGIVGVLFGDEIGAFIGEDGTTVVGITLLITAAAIWMIRNLRGRKIEGDLSTKDAV
IVGLAQAVAVTPGISRSGATLVASMLMGMKQDTALRFSFLLYIPVSLGSSILEIPNIVRDPNVQELWIPYLVAFITAFIA
SYFALKWFMNIMRHGNLKYFAYYCVIVGVLVLIFL

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=271, Percent_Identity=32.4723247232472, Blast_Score=123, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_OCEIH (Q8CXK0)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_692120.1
- GeneID:   1017359
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB1199
- NMPDR:   fig|221109.1.peg.1198
- HOGENOM:   HBG391969
- OMA:   FALLWYF
- ProtClustDB:   PRK12554
- BioCyc:   OIHE221109:OB1199-MONOMER
- BRENDA:   3.6.1.27
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 30588; Mature: 30588

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xd209530)-; HASH(0xe63bef4)-; HASH(0xe62c294)-; HASH(0xb54ddbc)-; HASH(0xe6366c4)-; HASH(0xe63c4e4)-; HASH(0xe6143b4)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVFENFWTIVHYFVLGLVQGITEPIPISSSGHIIIFRELFGIEARGLSFEIFVNLASLL
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHCCCCCCCHHHHHHHHHHHH
AVLIIYRKDIVRLAVNSWNFIFKQEKESKSDFMFVVYLVLATIPVGIVGVLFGDEIGAFI
HHHHHHHHHHHHHHHHCCHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GEDGTTVVGITLLITAAAIWMIRNLRGRKIEGDLSTKDAVIVGLAQAVAVTPGISRSGAT
CCCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHCCCCCCCCHHH
LVASMLMGMKQDTALRFSFLLYIPVSLGSSILEIPNIVRDPNVQELWIPYLVAFITAFIA
HHHHHHHCCCCCHHHHHHHHEEEHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
SYFALKWFMNIMRHGNLKYFAYYCVIVGVLVLIFL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
>Mature Secondary Structure
MNVFENFWTIVHYFVLGLVQGITEPIPISSSGHIIIFRELFGIEARGLSFEIFVNLASLL
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHCCCCCCCHHHHHHHHHHHH
AVLIIYRKDIVRLAVNSWNFIFKQEKESKSDFMFVVYLVLATIPVGIVGVLFGDEIGAFI
HHHHHHHHHHHHHHHHCCHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GEDGTTVVGITLLITAAAIWMIRNLRGRKIEGDLSTKDAVIVGLAQAVAVTPGISRSGAT
CCCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHCCCCCCCCHHH
LVASMLMGMKQDTALRFSFLLYIPVSLGSSILEIPNIVRDPNVQELWIPYLVAFITAFIA
HHHHHHHCCCCCHHHHHHHHEEEHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
SYFALKWFMNIMRHGNLKYFAYYCVIVGVLVLIFL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12235376