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The map label for this gene is bceS [H]

Identifier: 23098287

GI number: 23098287

Start: 883343

End: 884347

Strand: Direct

Name: bceS [H]

Synonym: OB0832

Alternate gene names: 23098287

Gene position: 883343-884347 (Clockwise)

Preceding gene: 23098286

Following gene: 23098288

Centisome position: 24.33

GC content: 34.03

Gene sequence:

>1005_bases
ATGATTTTCAGTTATTTGAAAGAAAGAATTAGTTGGATTATATTGTTTATAGTACTACAAGTAATCACCTTAATCGTTGG
ATACATGGATATGACGATACCAATGAAGTCCATTTACTATATTGTGTTTATCCAATTTGTTATTGGTATTATTTTCTTAT
GTATACGTTATAGGAAAGAAACTAAGTTTTATAAAGAGTTAATGGAATGGAAGCCAGTGATAGATTTAATAGATATGCCT
GAAGGAGACACAATATTTTCTAAAATTGTAACTAGAGCATTAGAGGATCAATCTCAGATTTACCGCAAAGAATATACGCA
GCTTCAGTTAGATGTACAACGAGAAAAAGATGATCTCCTTGTGTGGATACATGAAGTAAAAACGCCATTAACTACGATGC
AGTTAATGTTAGAACGGGTAGAGGGGAAAGAACTGCGTGCCCAATTGTCCTATGAATGGCTTCGTATTCATTTGTTATTA
GATCAACAACTTCATCAACGAAGAATTCCTTTTATGAAAAATGACTTGTATATAGAAAATGTAGATTTGCAATCTATCAT
TAACGAAGAAATTAGAACATTACGTTCTTGGTGTATGCAGAAAGGGATAGGCTTTCAAATTGAACTAAATGTCACTCAGA
TTCTTTCGGATGCGAAGTGGCTGCATTTTATACTCCGTCAAATTATCACCAACGCTGTTAAGTATAGTGAAAACAATGAC
ATAACGATTGAAAGTTTAGTCATTAACAATCAACATACACTTCAAATATCAGACAAGGGGCGGGGAATCTCTGCTAAAGA
TTTACCTCGTATTTTTGAGAAAGGTTTTACATCAACCAAGGAACATTTTGATCAAGGTTCCTCAGGCATGGGTTTATACT
TGGCGGTACAAGCAGCCGATTCATTAGGCATTCGAATAGAAGTTACTTCAGAATGGAGTAGAGGGACTTGTTTTCAGTTG
ATTTTCCCAAAAAAGAATGAATTATTACATCTAACAAGCATGTGA

Upstream 100 bases:

>100_bases
ATGTAAATAGACTTCGTAAAAGCCTTGACGACATAGGACTTGGGAAATTTATTGAAACGAGGGTTGGCCAAGGTTACATA
GCGATAGAGGAGTAAGACAA

Downstream 100 bases:

>100_bases
CAGCAATGTCACATGCTTTATTATATTGTTCGGAGAAACGAAGGAAATTCGTTATTATTATACGATAAAATAGGTTCATA
CTAGAGATTAGATATAAAAA

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MIFSYLKERISWIILFIVLQVITLIVGYMDMTIPMKSIYYIVFIQFVIGIIFLCIRYRKETKFYKELMEWKPVIDLIDMP
EGDTIFSKIVTRALEDQSQIYRKEYTQLQLDVQREKDDLLVWIHEVKTPLTTMQLMLERVEGKELRAQLSYEWLRIHLLL
DQQLHQRRIPFMKNDLYIENVDLQSIINEEIRTLRSWCMQKGIGFQIELNVTQILSDAKWLHFILRQIITNAVKYSENND
ITIESLVINNQHTLQISDKGRGISAKDLPRIFEKGFTSTKEHFDQGSSGMGLYLAVQAADSLGIRIEVTSEWSRGTCFQL
IFPKKNELLHLTSM

Sequences:

>Translated_334_residues
MIFSYLKERISWIILFIVLQVITLIVGYMDMTIPMKSIYYIVFIQFVIGIIFLCIRYRKETKFYKELMEWKPVIDLIDMP
EGDTIFSKIVTRALEDQSQIYRKEYTQLQLDVQREKDDLLVWIHEVKTPLTTMQLMLERVEGKELRAQLSYEWLRIHLLL
DQQLHQRRIPFMKNDLYIENVDLQSIINEEIRTLRSWCMQKGIGFQIELNVTQILSDAKWLHFILRQIITNAVKYSENND
ITIESLVINNQHTLQISDKGRGISAKDLPRIFEKGFTSTKEHFDQGSSGMGLYLAVQAADSLGIRIEVTSEWSRGTCFQL
IFPKKNELLHLTSM
>Mature_334_residues
MIFSYLKERISWIILFIVLQVITLIVGYMDMTIPMKSIYYIVFIQFVIGIIFLCIRYRKETKFYKELMEWKPVIDLIDMP
EGDTIFSKIVTRALEDQSQIYRKEYTQLQLDVQREKDDLLVWIHEVKTPLTTMQLMLERVEGKELRAQLSYEWLRIHLLL
DQQLHQRRIPFMKNDLYIENVDLQSIINEEIRTLRSWCMQKGIGFQIELNVTQILSDAKWLHFILRQIITNAVKYSENND
ITIESLVINNQHTLQISDKGRGISAKDLPRIFEKGFTSTKEHFDQGSSGMGLYLAVQAADSLGIRIEVTSEWSRGTCFQL
IFPKKNELLHLTSM

Specific function: Member of the two-component regulatory system BceS/BceR involved in the regulation of bacitracin resistance. Activates BceR in response to extracellular bacitracin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=216, Percent_Identity=25.9259259259259, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI48994928, Length=239, Percent_Identity=26.7782426778243, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467 [H]

Pfam domain/function: PF02518 HATPase_c [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39411; Mature: 39411

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFSYLKERISWIILFIVLQVITLIVGYMDMTIPMKSIYYIVFIQFVIGIIFLCIRYRKE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TKFYKELMEWKPVIDLIDMPEGDTIFSKIVTRALEDQSQIYRKEYTQLQLDVQREKDDLL
HHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCE
VWIHEVKTPLTTMQLMLERVEGKELRAQLSYEWLRIHLLLDQQLHQRRIPFMKNDLYIEN
EEHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEC
VDLQSIINEEIRTLRSWCMQKGIGFQIELNVTQILSDAKWLHFILRQIITNAVKYSENND
CCHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ITIESLVINNQHTLQISDKGRGISAKDLPRIFEKGFTSTKEHFDQGSSGMGLYLAVQAAD
EEEEEEEECCCEEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHCCCCCCCEEEEEEEECC
SLGIRIEVTSEWSRGTCFQLIFPKKNELLHLTSM
CCCEEEEEECCCCCCCEEEEEECCCCCEEEECCC
>Mature Secondary Structure
MIFSYLKERISWIILFIVLQVITLIVGYMDMTIPMKSIYYIVFIQFVIGIIFLCIRYRKE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TKFYKELMEWKPVIDLIDMPEGDTIFSKIVTRALEDQSQIYRKEYTQLQLDVQREKDDLL
HHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCE
VWIHEVKTPLTTMQLMLERVEGKELRAQLSYEWLRIHLLLDQQLHQRRIPFMKNDLYIEN
EEHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEC
VDLQSIINEEIRTLRSWCMQKGIGFQIELNVTQILSDAKWLHFILRQIITNAVKYSENND
CCHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ITIESLVINNQHTLQISDKGRGISAKDLPRIFEKGFTSTKEHFDQGSSGMGLYLAVQAAD
EEEEEEEECCCEEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHCCCCCCCEEEEEEEECC
SLGIRIEVTSEWSRGTCFQLIFPKKNELLHLTSM
CCCEEEEEECCCCCCCEEEEEECCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11058132; 10086842 [H]