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The map label for this gene is bceR [H]

Identifier: 23098286

GI number: 23098286

Start: 882654

End: 883337

Strand: Direct

Name: bceR [H]

Synonym: OB0831

Alternate gene names: 23098286

Gene position: 882654-883337 (Clockwise)

Preceding gene: 23098285

Following gene: 23098287

Centisome position: 24.31

GC content: 33.19

Gene sequence:

>684_bases
TTGTTTCGAGTTCTTATAATTGAAGATGATCAAACATTGTTAAGTGAGTTAATCAGCCAGTTAAGTCAATGGGATTATGA
AACCTATGGAATGGAAGATTTTAATTTAGTAATGGAGCGTTATAATGAAATTCAACCTGATTTGATTATTATAGATATTC
AACTTCCAAAATATGATGGTTTCCATTGGTGTAGAACGATACGATCTCACTCTGATGTACCAATCATTTTTCTATCTAGT
AGAGACCATCCCATGGATATGGTAATGGCGATGCAACTTGGTGCAGATGATTACGTTCAAAAACCATTTCATTTTGAAGT
ACTACTTGCTAAAATCCAAGCAATTCTTCGCAGAACTTATCGTTATAGTCAAACTACAAACGTTGATATAAAAATTTGGA
ATCAAGCTACCATTAACTTTAGTAAATGTGATATTCAATATAAGGGTGGTAGTGTTGAGTTAAGTAAAAATGAAAGTAGT
ATTCTTCGCATTTTAGTAGATCAAAAAAATCAGATTGTTTCTCGAGATGAACTAATTCGAGCATTGTGGGATGATGAGCG
ATTTATTAGTGATAATACACTTACTGTAAATGTAAATAGACTTCGTAAAAGCCTTGACGACATAGGACTTGGGAAATTTA
TTGAAACGAGGGTTGGCCAAGGTTACATAGCGATAGAGGAGTAA

Upstream 100 bases:

>100_bases
GGAATATGCTCCAGAACGAAAGACAGATCCGGGCGCGCTCTTTGATTGGGAACGGTTAATGAGTGATTTCGAGAATTAGA
GAATGGAGGTATAGTACAAT

Downstream 100 bases:

>100_bases
GACAAATGATTTTCAGTTATTTGAAAGAAAGAATTAGTTGGATTATATTGTTTATAGTACTACAAGTAATCACCTTAATC
GTTGGATACATGGATATGAC

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MFRVLIIEDDQTLLSELISQLSQWDYETYGMEDFNLVMERYNEIQPDLIIIDIQLPKYDGFHWCRTIRSHSDVPIIFLSS
RDHPMDMVMAMQLGADDYVQKPFHFEVLLAKIQAILRRTYRYSQTTNVDIKIWNQATINFSKCDIQYKGGSVELSKNESS
ILRILVDQKNQIVSRDELIRALWDDERFISDNTLTVNVNRLRKSLDDIGLGKFIETRVGQGYIAIEE

Sequences:

>Translated_227_residues
MFRVLIIEDDQTLLSELISQLSQWDYETYGMEDFNLVMERYNEIQPDLIIIDIQLPKYDGFHWCRTIRSHSDVPIIFLSS
RDHPMDMVMAMQLGADDYVQKPFHFEVLLAKIQAILRRTYRYSQTTNVDIKIWNQATINFSKCDIQYKGGSVELSKNESS
ILRILVDQKNQIVSRDELIRALWDDERFISDNTLTVNVNRLRKSLDDIGLGKFIETRVGQGYIAIEE
>Mature_227_residues
MFRVLIIEDDQTLLSELISQLSQWDYETYGMEDFNLVMERYNEIQPDLIIIDIQLPKYDGFHWCRTIRSHSDVPIIFLSS
RDHPMDMVMAMQLGADDYVQKPFHFEVLLAKIQAILRRTYRYSQTTNVDIKIWNQATINFSKCDIQYKGGSVELSKNESS
ILRILVDQKNQIVSRDELIRALWDDERFISDNTLTVNVNRLRKSLDDIGLGKFIETRVGQGYIAIEE

Specific function: Member of the two-component regulatory system BceS/BceR involved in the regulation of bacitracin resistance. When activated by BceS, binds to the upstream region of the bceAB promoter and up-regulates the expression of these two genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=221, Percent_Identity=29.4117647058824, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=26.457399103139, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=28.9592760180996, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=30.4932735426009, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=25.6410256410256, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=29.4642857142857, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=31.6964285714286, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI2367329, Length=238, Percent_Identity=28.5714285714286, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790552, Length=227, Percent_Identity=29.9559471365639, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1790863, Length=225, Percent_Identity=26.6666666666667, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786784, Length=231, Percent_Identity=29.4372294372294, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=27.5555555555556, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1789402, Length=229, Percent_Identity=28.3842794759825, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=27.9661016949153, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788550, Length=116, Percent_Identity=28.448275862069, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26635; Mature: 26635

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRVLIIEDDQTLLSELISQLSQWDYETYGMEDFNLVMERYNEIQPDLIIIDIQLPKYDG
CEEEEEEECCHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCC
FHWCRTIRSHSDVPIIFLSSRDHPMDMVMAMQLGADDYVQKPFHFEVLLAKIQAILRRTY
HHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHH
RYSQTTNVDIKIWNQATINFSKCDIQYKGGSVELSKNESSILRILVDQKNQIVSRDELIR
HCCCCCCEEEEEECCEEEEEEEEEEEECCCEEEECCCCCCEEEEEECCCCCCCCHHHHHH
ALWDDERFISDNTLTVNVNRLRKSLDDIGLGKFIETRVGQGYIAIEE
HHCCCCEEECCCEEEEEHHHHHHHHHHCCCCHHHHHHCCCCEEEEEC
>Mature Secondary Structure
MFRVLIIEDDQTLLSELISQLSQWDYETYGMEDFNLVMERYNEIQPDLIIIDIQLPKYDG
CEEEEEEECCHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCC
FHWCRTIRSHSDVPIIFLSSRDHPMDMVMAMQLGADDYVQKPFHFEVLLAKIQAILRRTY
HHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHH
RYSQTTNVDIKIWNQATINFSKCDIQYKGGSVELSKNESSILRILVDQKNQIVSRDELIR
HCCCCCCEEEEEECCEEEEEEEEEEEECCCEEEECCCCCCEEEEEECCCCCCCCHHHHHH
ALWDDERFISDNTLTVNVNRLRKSLDDIGLGKFIETRVGQGYIAIEE
HHCCCCEEECCCEEEEEHHHHHHHHHHCCCCHHHHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]