Click here to switch to the map view.

The map label for this gene is stc [H]

Identifier: 23098268

GI number: 23098268

Start: 866316

End: 868037

Strand: Direct

Name: stc [H]

Synonym: OB0813

Alternate gene names: 23098268

Gene position: 866316-868037 (Clockwise)

Preceding gene: 23098267

Following gene: 23098269

Centisome position: 23.86

GC content: 34.55

Gene sequence:

>1722_bases
ATGACTGACAAAATCATTGATTGGATGTATCCGAATCCACTTTATTTACATCCAGAAGAACCTTTAAAACGTGCGCTTCA
CATTTTATTGGAAAATAATCTGACAGAAATAGCAGTAGTAGAAAATCAGAAATGGAAAGGGATAATTAAATTACAGGATG
TGGTCCAAAAAGATAATGATGAAAAAGTTAGCTCATTTATAAGGAGTTGTGATCGAGTGGCTTCTGCTGACTTACTAATA
GATAAGCTTCAAGATATCCCTACATATATTGTTAATGATGAAGGAGAATTAATAGGAGAAATTACAGGTAAGGAATGGCT
TCATTATCATACAACGATAACGAAAGAATTAAAGCAAAAAGAAGAAATGTTACATTTATACGAAATGGTATTTGATACTG
CATACGAAGGGTTGACTGTGGTAGATGATAAAGGGATTATTCGCTTATTTAATGAAGCATATAGTAGATATGTAAAAGTA
CCTACAGAAGAAGCAATTGGAAAAGATGCTGCATTAATTATTGAAAATACTCGATTACCTGTGGTGCTAAAAACAGGTGT
ACCAGAACGCAGTCAAGCTCATCGATTACAAGGTCAGAATCTTGTCGTACATCGAATTCCTATATGGAAAGACAATAAAG
TGGTTGCTGCAGCAGGCATCTTGGTTTATGAAGGGGTATCTGAAATATATCAAGTTATCGATCAGATGGAAGAATTAGAT
AAGACAAAGCATAGTAAGTTTACTAAAGATCCCAATAAAAAAAATTCACTGACTCGATTTGAAGATTTACTAGGTGATAG
CCCGTGTTTTACGAAAACTAAGAAAATAGCTAGAAAAGCTTCGCAATCAAAAGCACCGGTCTTAATAACAGGGGAGAGCG
GAGTTGGGAAAGATATTGTTGCCCAAGCGATTCATAATGAGAGTCCGATAACTAGAGGAAGATTTATAAGCGTAAATTGT
GCCGCTATTCCAGAAGCACTATTAGAATCTGAATTGTTCGGTTACAGTTCGGGAGCATTTACTGGCGCAGAAAAAGGAGG
AAAACCTGGAAAGATAGAATTAGCTCATAAGGGGACGCTTTTTCTAGATGAAATAGGTGATATGCCATTAACCATGCAAG
CTAAAATTTTACGTGTTATTCAAGAAAAAAGTGTGGAAAGAGTAGGAAGTAATCATCAATCAAATATCGATTTCAGGTTG
ATAACCGCTACAAATAAAGACATCAAGCAAATGGTTCATGAAGGTACGTTTCGAGAAGATTTATATTATCGTTTGTATGT
AATACCTATTCATATTCCTTCTTTACGCGAGAGGGCGGAGGATATCCCAATCATTGTTTCCCATAAAATAGCCGAATTAA
ATAATGAATATGGTGATAGAAAAACGATTGATCAATTAGTAGTCCAATGGATGTATACTCAACCATGGAAAGGAAACATT
AGGGAGCTTATCAATTTTTTAGAACGATTATATGTGTTGTCGGAATCCCAACATATGACATTAGATAATTTACCTGATGA
TATTGATGACAAACAACGCTTATCATCGTATAACTTTTTAGCGAATAAAAAAGTAGCGGAATCATTATCGGAAGAAGAAG
AGAGAGATCGTATAAAAGAAACATTAGAACATGTAAAAGGCAATAAAACAAAGGCTGCAAAATTATTAGGAATATCGCGT
GCTACACTCTATAATAAACTATCTCGTTATACACTTGAATAA

Upstream 100 bases:

>100_bases
GTACCTTATAAGCTTATTAGATTTATACGTTCACATAAGTAGTAGTACTACACTTAAATAACAGAATTTTTATAAATTAA
TTTTGGAATGGGGGATACAT

Downstream 100 bases:

>100_bases
ACATGTCAAATTAGGCAGTTTTGACATTGAGTGTCTATACAATTTGACAATATAATACCTTGAATGTAGGGGAAGTGACT
TCAATTTGAGTTGGCATGCT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 573; Mature: 572

Protein sequence:

>573_residues
MTDKIIDWMYPNPLYLHPEEPLKRALHILLENNLTEIAVVENQKWKGIIKLQDVVQKDNDEKVSSFIRSCDRVASADLLI
DKLQDIPTYIVNDEGELIGEITGKEWLHYHTTITKELKQKEEMLHLYEMVFDTAYEGLTVVDDKGIIRLFNEAYSRYVKV
PTEEAIGKDAALIIENTRLPVVLKTGVPERSQAHRLQGQNLVVHRIPIWKDNKVVAAAGILVYEGVSEIYQVIDQMEELD
KTKHSKFTKDPNKKNSLTRFEDLLGDSPCFTKTKKIARKASQSKAPVLITGESGVGKDIVAQAIHNESPITRGRFISVNC
AAIPEALLESELFGYSSGAFTGAEKGGKPGKIELAHKGTLFLDEIGDMPLTMQAKILRVIQEKSVERVGSNHQSNIDFRL
ITATNKDIKQMVHEGTFREDLYYRLYVIPIHIPSLRERAEDIPIIVSHKIAELNNEYGDRKTIDQLVVQWMYTQPWKGNI
RELINFLERLYVLSESQHMTLDNLPDDIDDKQRLSSYNFLANKKVAESLSEEEERDRIKETLEHVKGNKTKAAKLLGISR
ATLYNKLSRYTLE

Sequences:

>Translated_573_residues
MTDKIIDWMYPNPLYLHPEEPLKRALHILLENNLTEIAVVENQKWKGIIKLQDVVQKDNDEKVSSFIRSCDRVASADLLI
DKLQDIPTYIVNDEGELIGEITGKEWLHYHTTITKELKQKEEMLHLYEMVFDTAYEGLTVVDDKGIIRLFNEAYSRYVKV
PTEEAIGKDAALIIENTRLPVVLKTGVPERSQAHRLQGQNLVVHRIPIWKDNKVVAAAGILVYEGVSEIYQVIDQMEELD
KTKHSKFTKDPNKKNSLTRFEDLLGDSPCFTKTKKIARKASQSKAPVLITGESGVGKDIVAQAIHNESPITRGRFISVNC
AAIPEALLESELFGYSSGAFTGAEKGGKPGKIELAHKGTLFLDEIGDMPLTMQAKILRVIQEKSVERVGSNHQSNIDFRL
ITATNKDIKQMVHEGTFREDLYYRLYVIPIHIPSLRERAEDIPIIVSHKIAELNNEYGDRKTIDQLVVQWMYTQPWKGNI
RELINFLERLYVLSESQHMTLDNLPDDIDDKQRLSSYNFLANKKVAESLSEEEERDRIKETLEHVKGNKTKAAKLLGISR
ATLYNKLSRYTLE
>Mature_572_residues
TDKIIDWMYPNPLYLHPEEPLKRALHILLENNLTEIAVVENQKWKGIIKLQDVVQKDNDEKVSSFIRSCDRVASADLLID
KLQDIPTYIVNDEGELIGEITGKEWLHYHTTITKELKQKEEMLHLYEMVFDTAYEGLTVVDDKGIIRLFNEAYSRYVKVP
TEEAIGKDAALIIENTRLPVVLKTGVPERSQAHRLQGQNLVVHRIPIWKDNKVVAAAGILVYEGVSEIYQVIDQMEELDK
TKHSKFTKDPNKKNSLTRFEDLLGDSPCFTKTKKIARKASQSKAPVLITGESGVGKDIVAQAIHNESPITRGRFISVNCA
AIPEALLESELFGYSSGAFTGAEKGGKPGKIELAHKGTLFLDEIGDMPLTMQAKILRVIQEKSVERVGSNHQSNIDFRLI
TATNKDIKQMVHEGTFREDLYYRLYVIPIHIPSLRERAEDIPIIVSHKIAELNNEYGDRKTIDQLVVQWMYTQPWKGNIR
ELINFLERLYVLSESQHMTLDNLPDDIDDKQRLSSYNFLANKKVAESLSEEEERDRIKETLEHVKGNKTKAAKLLGISRA
TLYNKLSRYTLE

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=316, Percent_Identity=44.3037974683544, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI1789233, Length=459, Percent_Identity=33.9869281045752, Blast_Score=237, Evalue=2e-63,
Organism=Escherichia coli, GI1788905, Length=316, Percent_Identity=40.5063291139241, Blast_Score=234, Evalue=9e-63,
Organism=Escherichia coli, GI1790437, Length=313, Percent_Identity=44.408945686901, Blast_Score=231, Evalue=1e-61,
Organism=Escherichia coli, GI1789087, Length=350, Percent_Identity=40, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI1790299, Length=332, Percent_Identity=38.5542168674699, Blast_Score=226, Evalue=4e-60,
Organism=Escherichia coli, GI87082117, Length=302, Percent_Identity=41.7218543046358, Blast_Score=222, Evalue=5e-59,
Organism=Escherichia coli, GI1786524, Length=366, Percent_Identity=36.8852459016393, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI87082152, Length=326, Percent_Identity=35.2760736196319, Blast_Score=191, Evalue=8e-50,
Organism=Escherichia coli, GI87081872, Length=319, Percent_Identity=37.3040752351097, Blast_Score=186, Evalue=4e-48,
Organism=Escherichia coli, GI87081858, Length=460, Percent_Identity=28.0434782608696, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1787583, Length=318, Percent_Identity=33.9622641509434, Blast_Score=173, Evalue=3e-44,
Organism=Escherichia coli, GI1789828, Length=314, Percent_Identity=35.3503184713376, Blast_Score=154, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 65378; Mature: 65247

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS50112 PAS ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKIIDWMYPNPLYLHPEEPLKRALHILLENNLTEIAVVENQKWKGIIKLQDVVQKDND
CCCCCEECCCCCCEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCCH
EKVSSFIRSCDRVASADLLIDKLQDIPTYIVNDEGELIGEITGKEWLHYHTTITKELKQK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEECCCCHHHHHHHHHHHHHHHH
EEMLHLYEMVFDTAYEGLTVVDDKGIIRLFNEAYSRYVKVPTEEAIGKDAALIIENTRLP
HHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHEECCCCHHHHCCCCEEEEECCCCC
VVLKTGVPERSQAHRLQGQNLVVHRIPIWKDNKVVAAAGILVYEGVSEIYQVIDQMEELD
EEEECCCCCHHHHHHCCCCCEEEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
KTKHSKFTKDPNKKNSLTRFEDLLGDSPCFTKTKKIARKASQSKAPVLITGESGVGKDIV
HHHHHCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHH
AQAIHNESPITRGRFISVNCAAIPEALLESELFGYSSGAFTGAEKGGKPGKIELAHKGTL
HHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCE
FLDEIGDMPLTMQAKILRVIQEKSVERVGSNHQSNIDFRLITATNKDIKQMVHEGTFRED
EEHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHCCCCHHC
LYYRLYVIPIHIPSLRERAEDIPIIVSHKIAELNNEYGDRKTIDQLVVQWMYTQPWKGNI
CEEEEEEEEEECHHHHHHHCCCCEEEHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCH
RELINFLERLYVLSESQHMTLDNLPDDIDDKQRLSSYNFLANKKVAESLSEEEERDRIKE
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLEHVKGNKTKAAKLLGISRATLYNKLSRYTLE
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TDKIIDWMYPNPLYLHPEEPLKRALHILLENNLTEIAVVENQKWKGIIKLQDVVQKDND
CCCCEECCCCCCEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCCH
EKVSSFIRSCDRVASADLLIDKLQDIPTYIVNDEGELIGEITGKEWLHYHTTITKELKQK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEECCCCHHHHHHHHHHHHHHHH
EEMLHLYEMVFDTAYEGLTVVDDKGIIRLFNEAYSRYVKVPTEEAIGKDAALIIENTRLP
HHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHEECCCCHHHHCCCCEEEEECCCCC
VVLKTGVPERSQAHRLQGQNLVVHRIPIWKDNKVVAAAGILVYEGVSEIYQVIDQMEELD
EEEECCCCCHHHHHHCCCCCEEEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
KTKHSKFTKDPNKKNSLTRFEDLLGDSPCFTKTKKIARKASQSKAPVLITGESGVGKDIV
HHHHHCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHH
AQAIHNESPITRGRFISVNCAAIPEALLESELFGYSSGAFTGAEKGGKPGKIELAHKGTL
HHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCE
FLDEIGDMPLTMQAKILRVIQEKSVERVGSNHQSNIDFRLITATNKDIKQMVHEGTFRED
EEHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHCCCCHHC
LYYRLYVIPIHIPSLRERAEDIPIIVSHKIAELNNEYGDRKTIDQLVVQWMYTQPWKGNI
CEEEEEEEEEECHHHHHHHCCCCEEEHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCH
RELINFLERLYVLSESQHMTLDNLPDDIDDKQRLSSYNFLANKKVAESLSEEEERDRIKE
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLEHVKGNKTKAAKLLGISRATLYNKLSRYTLE
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA