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The map label for this gene is gmuC [H]

Identifier: 23098236

GI number: 23098236

Start: 837370

End: 838569

Strand: Direct

Name: gmuC [H]

Synonym: OB0781

Alternate gene names: 23098236

Gene position: 837370-838569 (Clockwise)

Preceding gene: 23098235

Following gene: 23098238

Centisome position: 23.06

GC content: 36.67

Gene sequence:

>1200_bases
ATGGAAAATAGCAAATTTATGCAGCTTATGGAACGTTTTTTTTTACCAATTGCAGATAAGCTTAATAATAATCGTTATTT
AAGTGCTTTGCGTGACGGATTTATGGTAGCATTGCCTATCATTATCTTTGGATCAATATTTGTCGTTATTGCTAATATCC
CATTTTTAGACCAATTACTAAGTGAAGATGCGTACAATGCGTATAAAGATGCGCTCGGACCAGCTTCAGCTGCAACGCTA
TCGATTATGGGAATGTTTGTCATTGTTGGGATTGCCTATAAACTGACTGCCTATTATGAGGGGGACGCTATATATGGAGG
AGTTACTGCATTAGCATCCTTCCTCATTTTGACACCTCAAGTGTTAGAAGATGTTACAGGTGTAATCCCGACATCTAGTT
TAGGAGCAGAAGGGCTTTTTCTCGGCATCTTAACGGCATTTATTTCAACAGAGATTTTTCGTTTCTTTGTACAGAAAAAT
TGGATGATTAAAATGCCACCTGGTGTTCCAGAGGCAGTATCAAGGTCCTTTAGTTCCTTAATTCCAATTTCCTTTACACT
AACTATATTTTTGTTAATTCGTATTCTTTTTAGTATCACACCTTTTGAAACAATACAAAACTTTATTTATTCTGTTATTC
AAGAACCAATAACTGCATTGGGAAGTGGATTGCCTGCAGCGATTATTGCAGTCCTTTTAATCCAGGTTTTTTGGTTCTTT
GGTTTACATGGTCAGATCATCGTAAATTCTATAATGGATCCAATTTGGATGACACTGTCTTTAGAAAATTATGAAGCATA
TCAAGCGGGAGAAGAAAGACTGCATATCGTAAACAACCAATTTATCGATACCTTTATTGTTGGAATGGGTGGATCAGGAA
TGACGATGGCAGTTATCCTTGGTCTATTTATAGTGGCTAAAAGTAGGCAATTGAAACAACTCAGTAAAATTGGTGGTCCA
CCTTCAGTATTTAATGTAAATGAACCGATCATTTTCGGGTTACCCATCATTCTTAATCCGCTAGTTTTAATACCTTGGTT
ATTAGCACCAGTTGTTATTACAATTGTTACTTATTTTTCTATGGCAATAGGCCTTGTTCCCTGTTTCTACTGGAGTACAT
GTACCATGGACGACTCCAATCTTCATCGGTGGAATGCTGACAACAAATTCGATTGCTGGTGGAATTATGCAGTTAGTTAA

Upstream 100 bases:

>100_bases
TACTTTAGTGGTTGATTATAATCGTAACCTGGGACAAGGTAGCTTAATGAGCTTTAAAAGATAAAAGTATTAAATAAATG
AATAATAAAAGGAGTTTAAA

Downstream 100 bases:

>100_bases
CCTAGTAATTGTCACGCTCATTTGGATCCCATTTTTAAAATTATTAGATAAACGGTATTTTAGTGAGGAATTAGTAGGTG
CGGGTAAGGAAGTGGCAGCG

Product: PTS system cellobiose-specific enzyme II C component

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: Glucomannan utilization protein C; PTS system oligo-beta-mannoside-specific EIIC component [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MENSKFMQLMERFFLPIADKLNNNRYLSALRDGFMVALPIIIFGSIFVVIANIPFLDQLLSEDAYNAYKDALGPASAATL
SIMGMFVIVGIAYKLTAYYEGDAIYGGVTALASFLILTPQVLEDVTGVIPTSSLGAEGLFLGILTAFISTEIFRFFVQKN
WMIKMPPGVPEAVSRSFSSLIPISFTLTIFLLIRILFSITPFETIQNFIYSVIQEPITALGSGLPAAIIAVLLIQVFWFF
GLHGQIIVNSIMDPIWMTLSLENYEAYQAGEERLHIVNNQFIDTFIVGMGGSGMTMAVILGLFIVAKSRQLKQLSKIGGP
PSVFNVNEPIIFGLPIILNPLVLIPWLLAPVVITIVTYFSMAIGLVPCFYWSTCTMDDSNLHRWNADNKFDCWWNYAVS

Sequences:

>Translated_399_residues
MENSKFMQLMERFFLPIADKLNNNRYLSALRDGFMVALPIIIFGSIFVVIANIPFLDQLLSEDAYNAYKDALGPASAATL
SIMGMFVIVGIAYKLTAYYEGDAIYGGVTALASFLILTPQVLEDVTGVIPTSSLGAEGLFLGILTAFISTEIFRFFVQKN
WMIKMPPGVPEAVSRSFSSLIPISFTLTIFLLIRILFSITPFETIQNFIYSVIQEPITALGSGLPAAIIAVLLIQVFWFF
GLHGQIIVNSIMDPIWMTLSLENYEAYQAGEERLHIVNNQFIDTFIVGMGGSGMTMAVILGLFIVAKSRQLKQLSKIGGP
PSVFNVNEPIIFGLPIILNPLVLIPWLLAPVVITIVTYFSMAIGLVPCFYWSTCTMDDSNLHRWNADNKFDCWWNYAVS
>Mature_399_residues
MENSKFMQLMERFFLPIADKLNNNRYLSALRDGFMVALPIIIFGSIFVVIANIPFLDQLLSEDAYNAYKDALGPASAATL
SIMGMFVIVGIAYKLTAYYEGDAIYGGVTALASFLILTPQVLEDVTGVIPTSSLGAEGLFLGILTAFISTEIFRFFVQKN
WMIKMPPGVPEAVSRSFSSLIPISFTLTIFLLIRILFSITPFETIQNFIYSVIQEPITALGSGLPAAIIAVLLIQVFWFF
GLHGQIIVNSIMDPIWMTLSLENYEAYQAGEERLHIVNNQFIDTFIVGMGGSGMTMAVILGLFIVAKSRQLKQLSKIGGP
PSVFNVNEPIIFGLPIILNPLVLIPWLLAPVVITIVTYFSMAIGLVPCFYWSTCTMDDSNLHRWNADNKFDCWWNYAVS

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=387, Percent_Identity=30.4909560723514, Blast_Score=182, Evalue=5e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: NA

Molecular weight: Translated: 44276; Mature: 44276

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS00107 PROTEIN_KINASE_ATP ; PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENSKFMQLMERFFLPIADKLNNNRYLSALRDGFMVALPIIIFGSIFVVIANIPFLDQLL
CCCHHHHHHHHHHHCHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
SEDAYNAYKDALGPASAATLSIMGMFVIVGIAYKLTAYYEGDAIYGGVTALASFLILTPQ
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHCHH
VLEDVTGVIPTSSLGAEGLFLGILTAFISTEIFRFFVQKNWMIKMPPGVPEAVSRSFSSL
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHH
IPISFTLTIFLLIRILFSITPFETIQNFIYSVIQEPITALGSGLPAAIIAVLLIQVFWFF
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
GLHGQIIVNSIMDPIWMTLSLENYEAYQAGEERLHIVNNQFIDTFIVGMGGSGMTMAVIL
CCCHHHHHHHHHHHHEEEEEECCCHHHHCCHHHHHHHHHHHHHHHHEECCCCCHHHHHHH
GLFIVAKSRQLKQLSKIGGPPSVFNVNEPIIFGLPIILNPLVLIPWLLAPVVITIVTYFS
HHHHHHCCHHHHHHHHCCCCCCEEECCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
MAIGLVPCFYWSTCTMDDSNLHRWNADNKFDCWWNYAVS
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCC
>Mature Secondary Structure
MENSKFMQLMERFFLPIADKLNNNRYLSALRDGFMVALPIIIFGSIFVVIANIPFLDQLL
CCCHHHHHHHHHHHCHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
SEDAYNAYKDALGPASAATLSIMGMFVIVGIAYKLTAYYEGDAIYGGVTALASFLILTPQ
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHCHH
VLEDVTGVIPTSSLGAEGLFLGILTAFISTEIFRFFVQKNWMIKMPPGVPEAVSRSFSSL
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHH
IPISFTLTIFLLIRILFSITPFETIQNFIYSVIQEPITALGSGLPAAIIAVLLIQVFWFF
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
GLHGQIIVNSIMDPIWMTLSLENYEAYQAGEERLHIVNNQFIDTFIVGMGGSGMTMAVIL
CCCHHHHHHHHHHHHEEEEEECCCHHHHCCHHHHHHHHHHHHHHHHEECCCCCHHHHHHH
GLFIVAKSRQLKQLSKIGGPPSVFNVNEPIIFGLPIILNPLVLIPWLLAPVVITIVTYFS
HHHHHHCCHHHHHHHHCCCCCCEEECCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
MAIGLVPCFYWSTCTMDDSNLHRWNADNKFDCWWNYAVS
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377 [H]