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The map label for this gene is pabA [H]

Identifier: 23098156

GI number: 23098156

Start: 741129

End: 741743

Strand: Direct

Name: pabA [H]

Synonym: OB0701

Alternate gene names: 23098156

Gene position: 741129-741743 (Clockwise)

Preceding gene: 23098155

Following gene: 23098157

Centisome position: 20.41

GC content: 34.96

Gene sequence:

>615_bases
ATGCTATTAATTATAGATAACTACGATTCTTTTACATATAACCTTGTACATTATTTGGAGAAACTTTCGATTGAGTTAAT
GGTAATTAAAAATGACCAAATTACTATTAAGGAAATCGCTGAGTTAGATCCTGATTATATATTATTATCACCGGGACCGC
ATAATCCGGATCAAGCAGGGATTACCTTAGACGTGATTACGTTTTTTCATGATAAAATACCAATTTTAGGAGTTTGTCTT
GGACATCAGGCAATTGGACAAGCATTTGGTGCGAATATTATAAAAACCACCCCAATGCATGGAAAACGGTCAACTATATC
TCATGATGTTAAAACGGTATTTAAGGACATACCCTCTCCTTATTTAGTAACACGGTATCACTCATTAGTGATTGAACGAA
CTTCATTACCCGAAGAGTTAGTGATTACATCTGTATCAGAAGACGGAGAGATAATGGGAGTTCGACATACCACATTCCCA
ATAGAGGGTGTGCAATTTCATCCAGAGTCTATTTGGACAGAATATGGTGAAATATTACTTCATAATTTCCTTACTCATTA
TGCTAATTACAAGGAGCGCAGAAACGATGCAACAAGAAGGAAAATTGATATTTGA

Upstream 100 bases:

>100_bases
AATAGAGAGATTCTCTTTCGTAATCTTATTTATAACTGTTAAACTGCAGTCTATGCTATAGTTAAAATGAAATTTGAGAT
GGAAGCAATAGGAGAAAAAA

Downstream 100 bases:

>100_bases
TTTTGCATTTGATGAACAGAAAAAGAAAAGATTAGTTTTTTCAGATCCCGTTGATATGATTGTCGCTAATGCGAAATCTG
AAGTAATCTTTGCTATGGAA

Product: para-aminobenzoate synthase component I

Products: NA

Alternate protein names: Para-aminobenzoate synthase glutamine amidotransferase component II; ADC synthase; Anthranilate synthase component II [H]

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MLLIIDNYDSFTYNLVHYLEKLSIELMVIKNDQITIKEIAELDPDYILLSPGPHNPDQAGITLDVITFFHDKIPILGVCL
GHQAIGQAFGANIIKTTPMHGKRSTISHDVKTVFKDIPSPYLVTRYHSLVIERTSLPEELVITSVSEDGEIMGVRHTTFP
IEGVQFHPESIWTEYGEILLHNFLTHYANYKERRNDATRRKIDI

Sequences:

>Translated_204_residues
MLLIIDNYDSFTYNLVHYLEKLSIELMVIKNDQITIKEIAELDPDYILLSPGPHNPDQAGITLDVITFFHDKIPILGVCL
GHQAIGQAFGANIIKTTPMHGKRSTISHDVKTVFKDIPSPYLVTRYHSLVIERTSLPEELVITSVSEDGEIMGVRHTTFP
IEGVQFHPESIWTEYGEILLHNFLTHYANYKERRNDATRRKIDI
>Mature_204_residues
MLLIIDNYDSFTYNLVHYLEKLSIELMVIKNDQITIKEIAELDPDYILLSPGPHNPDQAGITLDVITFFHDKIPILGVCL
GHQAIGQAFGANIIKTTPMHGKRSTISHDVKTVFKDIPSPYLVTRYHSLVIERTSLPEELVITSVSEDGEIMGVRHTTFP
IEGVQFHPESIWTEYGEILLHNFLTHYANYKERRNDATRRKIDI

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine and also involved in the synthesis of anthranilate [H]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=185, Percent_Identity=52.972972972973, Blast_Score=207, Evalue=4e-55,
Organism=Escherichia coli, GI1787517, Length=188, Percent_Identity=39.3617021276596, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI1786215, Length=159, Percent_Identity=30.188679245283, Blast_Score=72, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6322638, Length=215, Percent_Identity=43.7209302325581, Blast_Score=186, Evalue=3e-48,
Organism=Saccharomyces cerevisiae, GI6324361, Length=210, Percent_Identity=31.4285714285714, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =2.6.1.85; =4.1.3.27 [H]

Molecular weight: Translated: 23313; Mature: 23313

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLIIDNYDSFTYNLVHYLEKLSIELMVIKNDQITIKEIAELDPDYILLSPGPHNPDQAG
CEEEEECCCCHHHHHHHHHHHCCEEEEEEECCCEEHHHHHHCCCCEEEECCCCCCCCCCC
ITLDVITFFHDKIPILGVCLGHQAIGQAFGANIIKTTPMHGKRSTISHDVKTVFKDIPSP
EEEEHEEHHHCCCCEEEEECCHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHCCCC
YLVTRYHSLVIERTSLPEELVITSVSEDGEIMGVRHTTFPIEGVQFHPESIWTEYGEILL
HHHHHHHHHEEECCCCCHHHEEEECCCCCCEEEEEECCCCCCCEEECHHHHHHHHHHHHH
HNFLTHYANYKERRNDATRRKIDI
HHHHHHHHHHHHHHCHHHHHCCCC
>Mature Secondary Structure
MLLIIDNYDSFTYNLVHYLEKLSIELMVIKNDQITIKEIAELDPDYILLSPGPHNPDQAG
CEEEEECCCCHHHHHHHHHHHCCEEEEEEECCCEEHHHHHHCCCCEEEECCCCCCCCCCC
ITLDVITFFHDKIPILGVCLGHQAIGQAFGANIIKTTPMHGKRSTISHDVKTVFKDIPSP
EEEEHEEHHHCCCCEEEEECCHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHCCCC
YLVTRYHSLVIERTSLPEELVITSVSEDGEIMGVRHTTFPIEGVQFHPESIWTEYGEILL
HHHHHHHHHEEECCCCCHHHEEEECCCCCCEEEEEECCCCCCCEEECHHHHHHHHHHHHH
HNFLTHYANYKERRNDATRRKIDI
HHHHHHHHHHHHHHCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]