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The map label for this gene is pabB [H]

Identifier: 23098157

GI number: 23098157

Start: 741715

End: 743472

Strand: Direct

Name: pabB [H]

Synonym: OB0702

Alternate gene names: 23098157

Gene position: 741715-743472 (Clockwise)

Preceding gene: 23098156

Following gene: 23098158

Centisome position: 20.43

GC content: 33.28

Gene sequence:

>1758_bases
ATGCAACAAGAAGGAAAATTGATATTTGATTTTGCATTTGATGAACAGAAAAAGAAAAGATTAGTTTTTTCAGATCCCGT
TGATATGATTGTCGCTAATGCGAAATCTGAAGTAATCTTTGCTATGGAAAAAATCGAAGCCTATATACATCAAGGATATT
ATGCAGGTGGGTATATCTCTTATGAAGCAGGAGAAGGTTTTGATGCTAATCTGAAAACATCGGATGACTTTGAGCTTCCG
TTAATTATGATGGGGATCTATAAAGAACCTTTAAATATAGTAGATGAACTGGAGTACCCGCGATTATCCCAGCGATTCGA
TTGGGAGATGTCTACTTCTAAAGAAAAATATCTAAAACAAGTATCATCTATCAAAAACTCTATAGCACAAGGTGATACAT
ATCAAGTTAACTATACCGTACGTTTACATTCAGGTGATGAGGTTAGTGATCATGATATATATGAAAAATTAAGTAAAGCT
CAACAAGCAAATTATTGCGCTCACTTACAGCTAGGTAGATATAGTATTGTATCAGCATCTCCAGAGTTGTTTTTTCAATT
AAAGAATGGAAAGTTACTAACGAAACCAATGAAAGGTACAATGAAACGTGGCAAAACTGCTGAAGAGGATATTCGGAATA
AGCAATTACTAACGGAATCGGTAAAAGATCAAGCTGAAAATTTAATGATTGTAGATTTATTACGAAACGATATCTCTAAA
ATTGCTAAAAAAGGTACTGTAACTGTACCAAAACTATTTAATATTGAGAGTTATCCTACTGTATTTCAAATGACATCTAC
AGTTACTGCAGAAATTGAAGAAAACATCCGGATAATAGATATATTTAAAGCATTATTTCCATGTGGGTCGATAACAGGTG
CGCCAAAGCAAAGTACAATGCAAATTATTCAAAAACTTGAAAACACCCCGAGAGAAGTTTATTGCGGAAGTATTGGATAT
ATTACACCGAATCAAGAGGCGCTTTTTAATGTAGCGATACGTACTGCAGTGATTGATACGGAACAAAACACAATTTCTTA
CGGTGTTGGTGGAGGTATTACTTGGGACTCTGTTCCAGAGGCTGAATATGAAGAGGCTTGGGCGAAGGCAGAAATACTCA
AATCTTTAAATGAGACAGATATTGAGTTGCTAGAGACAATGAAATATGAGAATGGGAACTTTTATTTAATAAGTAATCAC
TTAAATCGATTAAAAAAATCCGCTGAATATTTTAACTACTCCCTATCTATAAAAGAAATAAAACAAAAATTATATGAGTA
TGCGGAAGAAAACTTTAATCAACATCAAGTGTATAGAGTTCGATTATTAGTCAATAAACGCGGAGAAATTAAAATTAATT
CCACACCTATTTCATTGATAAATGAAAAAACAAATTACCGATTTCAACTTGCTGTAAGTCCAATAGATAAGAATAACCCA
TATTACTATCATAAGACGACCTTTCGTAAGATGTATGAAAAATTTCGAGAAGAATTAGGAAATGCGTTTGATATTTTACT
CTGGAATGATAAAGAAGAGTTAACGGAATTTACAATGGGAAATCTTGTTGTAAAAGTGGAAGAAGAATATTGGACTCCTC
CCGTAAAGTCTGGATTACTTGCTGGCACTTTTCGTCAACAACTAATTGAACAGAAGAAAATAAAGGAAAGAATCATATCT
AAGTCGGAATTAGAAAGTGTTGACGAAGTTTGGTTTATAAATAGTGTACGAGGTTGGGTGCAGATGTTTCAACAGTAA

Upstream 100 bases:

>100_bases
GGTGTGCAATTTCATCCAGAGTCTATTTGGACAGAATATGGTGAAATATTACTTCATAATTTCCTTACTCATTATGCTAA
TTACAAGGAGCGCAGAAACG

Downstream 100 bases:

>100_bases
AAATTCGGGTACACTACTCATAGGTCTTGAAGGATTACCTTTAATAATGAAAGGATGAGTTAAACATGAGTAAACACATT
GCAGTATTAGTTACAGATAT

Product: para-aminobenzoate synthase component II

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 585; Mature: 585

Protein sequence:

>585_residues
MQQEGKLIFDFAFDEQKKKRLVFSDPVDMIVANAKSEVIFAMEKIEAYIHQGYYAGGYISYEAGEGFDANLKTSDDFELP
LIMMGIYKEPLNIVDELEYPRLSQRFDWEMSTSKEKYLKQVSSIKNSIAQGDTYQVNYTVRLHSGDEVSDHDIYEKLSKA
QQANYCAHLQLGRYSIVSASPELFFQLKNGKLLTKPMKGTMKRGKTAEEDIRNKQLLTESVKDQAENLMIVDLLRNDISK
IAKKGTVTVPKLFNIESYPTVFQMTSTVTAEIEENIRIIDIFKALFPCGSITGAPKQSTMQIIQKLENTPREVYCGSIGY
ITPNQEALFNVAIRTAVIDTEQNTISYGVGGGITWDSVPEAEYEEAWAKAEILKSLNETDIELLETMKYENGNFYLISNH
LNRLKKSAEYFNYSLSIKEIKQKLYEYAEENFNQHQVYRVRLLVNKRGEIKINSTPISLINEKTNYRFQLAVSPIDKNNP
YYYHKTTFRKMYEKFREELGNAFDILLWNDKEELTEFTMGNLVVKVEEEYWTPPVKSGLLAGTFRQQLIEQKKIKERIIS
KSELESVDEVWFINSVRGWVQMFQQ

Sequences:

>Translated_585_residues
MQQEGKLIFDFAFDEQKKKRLVFSDPVDMIVANAKSEVIFAMEKIEAYIHQGYYAGGYISYEAGEGFDANLKTSDDFELP
LIMMGIYKEPLNIVDELEYPRLSQRFDWEMSTSKEKYLKQVSSIKNSIAQGDTYQVNYTVRLHSGDEVSDHDIYEKLSKA
QQANYCAHLQLGRYSIVSASPELFFQLKNGKLLTKPMKGTMKRGKTAEEDIRNKQLLTESVKDQAENLMIVDLLRNDISK
IAKKGTVTVPKLFNIESYPTVFQMTSTVTAEIEENIRIIDIFKALFPCGSITGAPKQSTMQIIQKLENTPREVYCGSIGY
ITPNQEALFNVAIRTAVIDTEQNTISYGVGGGITWDSVPEAEYEEAWAKAEILKSLNETDIELLETMKYENGNFYLISNH
LNRLKKSAEYFNYSLSIKEIKQKLYEYAEENFNQHQVYRVRLLVNKRGEIKINSTPISLINEKTNYRFQLAVSPIDKNNP
YYYHKTTFRKMYEKFREELGNAFDILLWNDKEELTEFTMGNLVVKVEEEYWTPPVKSGLLAGTFRQQLIEQKKIKERIIS
KSELESVDEVWFINSVRGWVQMFQQ
>Mature_585_residues
MQQEGKLIFDFAFDEQKKKRLVFSDPVDMIVANAKSEVIFAMEKIEAYIHQGYYAGGYISYEAGEGFDANLKTSDDFELP
LIMMGIYKEPLNIVDELEYPRLSQRFDWEMSTSKEKYLKQVSSIKNSIAQGDTYQVNYTVRLHSGDEVSDHDIYEKLSKA
QQANYCAHLQLGRYSIVSASPELFFQLKNGKLLTKPMKGTMKRGKTAEEDIRNKQLLTESVKDQAENLMIVDLLRNDISK
IAKKGTVTVPKLFNIESYPTVFQMTSTVTAEIEENIRIIDIFKALFPCGSITGAPKQSTMQIIQKLENTPREVYCGSIGY
ITPNQEALFNVAIRTAVIDTEQNTISYGVGGGITWDSVPEAEYEEAWAKAEILKSLNETDIELLETMKYENGNFYLISNH
LNRLKKSAEYFNYSLSIKEIKQKLYEYAEENFNQHQVYRVRLLVNKRGEIKINSTPISLINEKTNYRFQLAVSPIDKNNP
YYYHKTTFRKMYEKFREELGNAFDILLWNDKEELTEFTMGNLVVKVEEEYWTPPVKSGLLAGTFRQQLIEQKKIKERIIS
KSELESVDEVWFINSVRGWVQMFQQ

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=352, Percent_Identity=37.5, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI1787518, Length=278, Percent_Identity=28.4172661870504, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI87082077, Length=214, Percent_Identity=24.7663551401869, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1786809, Length=280, Percent_Identity=20.3571428571429, Blast_Score=66, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6320935, Length=272, Percent_Identity=34.5588235294118, Blast_Score=152, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6324361, Length=310, Percent_Identity=27.0967741935484, Blast_Score=100, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 67636; Mature: 67636

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQEGKLIFDFAFDEQKKKRLVFSDPVDMIVANAKSEVIFAMEKIEAYIHQGYYAGGYIS
CCCCCCEEEEEECCCHHHCCEEECCCHHHHEECCCCHHHHHHHHHHHHHHCCEEECCEEE
YEAGEGFDANLKTSDDFELPLIMMGIYKEPLNIVDELEYPRLSQRFDWEMSTSKEKYLKQ
ECCCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHH
VSSIKNSIAQGDTYQVNYTVRLHSGDEVSDHDIYEKLSKAQQANYCAHLQLGRYSIVSAS
HHHHHHHHHCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCEEEEECC
PELFFQLKNGKLLTKPMKGTMKRGKTAEEDIRNKQLLTESVKDQAENLMIVDLLRNDISK
CEEEEEECCCEEEECCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHH
IAKKGTVTVPKLFNIESYPTVFQMTSTVTAEIEENIRIIDIFKALFPCGSITGAPKQSTM
HHHCCCEECCEEECCCCCCHHEEEHHHHHHHHHCCCCCEEHHHHHCCCCCCCCCCCHHHH
QIIQKLENTPREVYCGSIGYITPNQEALFNVAIRTAVIDTEQNTISYGVGGGITWDSVPE
HHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHEEEECCCCEEEECCCCCCCCCCCCC
AEYEEAWAKAEILKSLNETDIELLETMKYENGNFYLISNHLNRLKKSAEYFNYSLSIKEI
HHHHHHHHHHHHHHHCCHHHHHHHHHHEECCCCEEEEHHHHHHHHHHHHHHEEEEEHHHH
KQKLYEYAEENFNQHQVYRVRLLVNKRGEIKINSTPISLINEKTNYRFQLAVSPIDKNNP
HHHHHHHHHCCCCCCCEEEEEEEECCCCCEEECCCCCEEEECCCCEEEEEEEECCCCCCC
YYYHKTTFRKMYEKFREELGNAFDILLWNDKEELTEFTMGNLVVKVEEEYWTPPVKSGLL
EEEEHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHCCEEEEEEHHHCCCCHHCCHH
AGTFRQQLIEQKKIKERIISKSELESVDEVWFINSVRGWVQMFQQ
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQQEGKLIFDFAFDEQKKKRLVFSDPVDMIVANAKSEVIFAMEKIEAYIHQGYYAGGYIS
CCCCCCEEEEEECCCHHHCCEEECCCHHHHEECCCCHHHHHHHHHHHHHHCCEEECCEEE
YEAGEGFDANLKTSDDFELPLIMMGIYKEPLNIVDELEYPRLSQRFDWEMSTSKEKYLKQ
ECCCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHH
VSSIKNSIAQGDTYQVNYTVRLHSGDEVSDHDIYEKLSKAQQANYCAHLQLGRYSIVSAS
HHHHHHHHHCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCEEEEECC
PELFFQLKNGKLLTKPMKGTMKRGKTAEEDIRNKQLLTESVKDQAENLMIVDLLRNDISK
CEEEEEECCCEEEECCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHH
IAKKGTVTVPKLFNIESYPTVFQMTSTVTAEIEENIRIIDIFKALFPCGSITGAPKQSTM
HHHCCCEECCEEECCCCCCHHEEEHHHHHHHHHCCCCCEEHHHHHCCCCCCCCCCCHHHH
QIIQKLENTPREVYCGSIGYITPNQEALFNVAIRTAVIDTEQNTISYGVGGGITWDSVPE
HHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHEEEECCCCEEEECCCCCCCCCCCCC
AEYEEAWAKAEILKSLNETDIELLETMKYENGNFYLISNHLNRLKKSAEYFNYSLSIKEI
HHHHHHHHHHHHHHHCCHHHHHHHHHHEECCCCEEEEHHHHHHHHHHHHHHEEEEEHHHH
KQKLYEYAEENFNQHQVYRVRLLVNKRGEIKINSTPISLINEKTNYRFQLAVSPIDKNNP
HHHHHHHHHCCCCCCCEEEEEEEECCCCCEEECCCCCEEEECCCCEEEEEEEECCCCCCC
YYYHKTTFRKMYEKFREELGNAFDILLWNDKEELTEFTMGNLVVKVEEEYWTPPVKSGLL
EEEEHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHCCEEEEEEHHHCCCCHHCCHH
AGTFRQQLIEQKKIKERIISKSELESVDEVWFINSVRGWVQMFQQ
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 11677609; 2251281 [H]