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The map label for this gene is groES

Identifier: 23098110

GI number: 23098110

Start: 689872

End: 690153

Strand: Direct

Name: groES

Synonym: OB0655

Alternate gene names: 23098110

Gene position: 689872-690153 (Clockwise)

Preceding gene: 23098107

Following gene: 23098111

Centisome position: 19.0

GC content: 36.17

Gene sequence:

>282_bases
ATGATTAAACCATTAGGAGATCGTGTTGTTATCGAACTTGTTGAACAAGAAGAAACAACTGCAAGCGGAATCGTACTTCC
AGACTCTGCAAAGGAAAAACCGCAGGAAGGTAAAGTAGTAGCAGTTGGTTCTGGACGTGTAGAAAATGGAGAAAAGATTG
CTCTTGAAGTTTCAGAAGGAGATCGAATCATTTTTTCTAAATTTGCTGGTACAGAAGTGAAATATGAAGGTACAGAATAC
TTAATTCTTCGTGAAAATGATATTTTAGCTATTATTGGCTAA

Upstream 100 bases:

>100_bases
TTTTTTTATAGAATTAATTATTATAATAATTGTGATTAGCACTCATCTATGAAGAGTGCTAATAAAATAAAATGATATCG
AATTAAGGAGGCAATTCTAC

Downstream 100 bases:

>100_bases
ACTCTTATGAAAAATTTAGATTAAAACGATAAATACGTAACTACATTCAAGGAGGAATAAAGAATGGCTAAAGACTTAAA
ATTTAGTGAAGACGCTCGTC

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10

Number of amino acids: Translated: 93; Mature: 93

Protein sequence:

>93_residues
MIKPLGDRVVIELVEQEETTASGIVLPDSAKEKPQEGKVVAVGSGRVENGEKIALEVSEGDRIIFSKFAGTEVKYEGTEY
LILRENDILAIIG

Sequences:

>Translated_93_residues
MIKPLGDRVVIELVEQEETTASGIVLPDSAKEKPQEGKVVAVGSGRVENGEKIALEVSEGDRIIFSKFAGTEVKYEGTEY
LILRENDILAIIG
>Mature_93_residues
MIKPLGDRVVIELVEQEETTASGIVLPDSAKEKPQEGKVVAVGSGRVENGEKIALEVSEGDRIIFSKFAGTEVKYEGTEY
LILRENDILAIIG

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Escherichia coli, GI1790585, Length=93, Percent_Identity=47.3118279569892, Blast_Score=70, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17555568, Length=92, Percent_Identity=44.5652173913043, Blast_Score=76, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6324594, Length=94, Percent_Identity=37.2340425531915, Blast_Score=63, Evalue=7e-12,
Organism=Drosophila melanogaster, GI21356029, Length=93, Percent_Identity=44.0860215053763, Blast_Score=69, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21358317, Length=90, Percent_Identity=43.3333333333333, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH10_OCEIH (Q8CXL4)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_691576.1
- ProteinModelPortal:   Q8CXL4
- SMR:   Q8CXL4
- GeneID:   1016060
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB0655
- NMPDR:   fig|221109.1.peg.661
- HOGENOM:   HBG703377
- OMA:   FGQYAGQ
- ProtClustDB:   PRK00364
- BioCyc:   OIHE221109:OB0655-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 10088; Mature: 10088

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKPLGDRVVIELVEQEETTASGIVLPDSAKEKPQEGKVVAVGSGRVENGEKIALEVSEG
CCCCCCCEEEEEEECCCCCCCCCEEECCCCCCCCCCCCEEEEECCCCCCCCEEEEEECCC
DRIIFSKFAGTEVKYEGTEYLILRENDILAIIG
CEEEEEECCCCEEEECCCEEEEEECCCEEEEEC
>Mature Secondary Structure
MIKPLGDRVVIELVEQEETTASGIVLPDSAKEKPQEGKVVAVGSGRVENGEKIALEVSEG
CCCCCCCEEEEEEECCCCCCCCCEEECCCCCCCCCCCCEEEEECCCCCCCCEEEEEECCC
DRIIFSKFAGTEVKYEGTEYLILRENDILAIIG
CEEEEEECCCCEEEECCCEEEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376