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The map label for this gene is ykoG [H]

Identifier: 23098049

GI number: 23098049

Start: 621066

End: 621755

Strand: Direct

Name: ykoG [H]

Synonym: OB0594

Alternate gene names: 23098049

Gene position: 621066-621755 (Clockwise)

Preceding gene: 23098048

Following gene: 23098050

Centisome position: 17.11

GC content: 35.07

Gene sequence:

>690_bases
ATGGCAGAACGTATATTAATTGTGGAAGATGAACAAAAAATTAGCAGAGTATTACAGTTAGAGCTTGAATACGAAGGTTA
TGAATCTGAAGTAGCTAGTAATGGAAAAGATGCATTAAATAAAATTGAACAAGAAAACTGGGATCTTGTACTACTAGATA
TTATGATTCCTCAGCTAAGTGGATTAGAAGTGTTAAGACGTGTTCGGAGAGCAGAAAATCAAACGCCGATCATCTTATTA
ACTGCTCGTGATGAGGTTCATGATAAAGTAAGTGGTCTCGATTTAGGTGCGAATGATTACATAACGAAACCATTTCAAAT
AGAAGAGTTACTCGCTCGTGTACGTGTGCATTTACGAAAAGTTGTGCAGGCAGCGAATGATAACCAGACTTTATCAGTAG
CAGATCTACAGGTGGATTTACATGCGTATGAGGTCACGCGTAACGGTGAAAAAATTGAATTAACACCTCGCGAATTTAAT
TTATTGGTGTGTTTACTAAAGAATAAAAATATTGTTCTTACTCGAGAACAGTTAATTGAATCGGTATGGGGATACGATTA
TTTTGGAGATACAAATGTGGTAGATGTTTATATTCGTTATTTACGCCAGAAAGTAGATAAAAACTTTGAGATACCGATAA
TTCAAACTGTACGTGGTGTAGGTTATACAATTAAGGAAGATAAACAATGA

Upstream 100 bases:

>100_bases
CTTCTAGAATGGTCGCTTTTTTGATAATTCCTAGTTTATAATTAAGGAGAAAATGGCCTTAATTTATATTTATATTTAAA
TGAAGGAAGGGGCATGATTC

Downstream 100 bases:

>100_bases
TATTTCGAAAGCTAATTAACTTTTTTTCTTCTATAACATTACGAAAAAAAATTATCTTCTTCTCAACCTTTTTTATGTTG
ATTTTAATATTAATTGTAAA

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MAERILIVEDEQKISRVLQLELEYEGYESEVASNGKDALNKIEQENWDLVLLDIMIPQLSGLEVLRRVRRAENQTPIILL
TARDEVHDKVSGLDLGANDYITKPFQIEELLARVRVHLRKVVQAANDNQTLSVADLQVDLHAYEVTRNGEKIELTPREFN
LLVCLLKNKNIVLTREQLIESVWGYDYFGDTNVVDVYIRYLRQKVDKNFEIPIIQTVRGVGYTIKEDKQ

Sequences:

>Translated_229_residues
MAERILIVEDEQKISRVLQLELEYEGYESEVASNGKDALNKIEQENWDLVLLDIMIPQLSGLEVLRRVRRAENQTPIILL
TARDEVHDKVSGLDLGANDYITKPFQIEELLARVRVHLRKVVQAANDNQTLSVADLQVDLHAYEVTRNGEKIELTPREFN
LLVCLLKNKNIVLTREQLIESVWGYDYFGDTNVVDVYIRYLRQKVDKNFEIPIIQTVRGVGYTIKEDKQ
>Mature_228_residues
AERILIVEDEQKISRVLQLELEYEGYESEVASNGKDALNKIEQENWDLVLLDIMIPQLSGLEVLRRVRRAENQTPIILLT
ARDEVHDKVSGLDLGANDYITKPFQIEELLARVRVHLRKVVQAANDNQTLSVADLQVDLHAYEVTRNGEKIELTPREFNL
LVCLLKNKNIVLTREQLIESVWGYDYFGDTNVVDVYIRYLRQKVDKNFEIPIIQTVRGVGYTIKEDKQ

Specific function: Probable member of the two-component regulatory system ykoH/ykoG [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=42.7927927927928, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI87082012, Length=221, Percent_Identity=42.0814479638009, Blast_Score=175, Evalue=2e-45,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=37.7777777777778, Blast_Score=157, Evalue=6e-40,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=39.2857142857143, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=37.5, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=35.3982300884956, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789402, Length=224, Percent_Identity=33.4821428571429, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=32.6086956521739, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1787375, Length=219, Percent_Identity=32.8767123287671, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=36.283185840708, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=38.1578947368421, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1787229, Length=233, Percent_Identity=33.0472103004292, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=30.7359307359307, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=42.0560747663551, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=31.8777292576419, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1790299, Length=110, Percent_Identity=31.8181818181818, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790437, Length=108, Percent_Identity=31.4814814814815, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1787487, Length=104, Percent_Identity=33.6538461538462, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788713, Length=122, Percent_Identity=30.327868852459, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1788191, Length=110, Percent_Identity=30, Blast_Score=62, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=107, Percent_Identity=34.5794392523364, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26507; Mature: 26376

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAERILIVEDEQKISRVLQLELEYEGYESEVASNGKDALNKIEQENWDLVLLDIMIPQLS
CCCEEEEEECHHHHHHHHEEEEECCCCHHHHHCCCHHHHHHHHCCCCCEEEEEECCCCCC
GLEVLRRVRRAENQTPIILLTARDEVHDKVSGLDLGANDYITKPFQIEELLARVRVHLRK
CHHHHHHHHHHCCCCCEEEEECCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
VVQAANDNQTLSVADLQVDLHAYEVTRNGEKIELTPREFNLLVCLLKNKNIVLTREQLIE
HHHHCCCCCEEEEEEEEEEEEEEEEECCCCEEEECCCCEEEEEEEECCCCEEEEHHHHHH
SVWGYDYFGDTNVVDVYIRYLRQKVDKNFEIPIIQTVRGVGYTIKEDKQ
HHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEECCCCC
>Mature Secondary Structure 
AERILIVEDEQKISRVLQLELEYEGYESEVASNGKDALNKIEQENWDLVLLDIMIPQLS
CCEEEEEECHHHHHHHHEEEEECCCCHHHHHCCCHHHHHHHHCCCCCEEEEEECCCCCC
GLEVLRRVRRAENQTPIILLTARDEVHDKVSGLDLGANDYITKPFQIEELLARVRVHLRK
CHHHHHHHHHHCCCCCEEEEECCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
VVQAANDNQTLSVADLQVDLHAYEVTRNGEKIELTPREFNLLVCLLKNKNIVLTREQLIE
HHHHCCCCCEEEEEEEEEEEEEEEEECCCCEEEECCCCEEEEEEEECCCCEEEEHHHHHH
SVWGYDYFGDTNVVDVYIRYLRQKVDKNFEIPIIQTVRGVGYTIKEDKQ
HHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]