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The map label for this gene is yfnA [H]

Identifier: 23097944

GI number: 23097944

Start: 518200

End: 519609

Strand: Reverse

Name: yfnA [H]

Synonym: OB0489

Alternate gene names: 23097944

Gene position: 519609-518200 (Counterclockwise)

Preceding gene: 23097945

Following gene: 28563908

Centisome position: 14.31

GC content: 38.51

Gene sequence:

>1410_bases
ATGAATGACTCGGATAAACTATTAAAATCACTAGGTAAAAAGGAAACTTTTGCACTTGCCTTTGGGGCTATGATTGGTTG
GGGATGGGTAGTTACTTCTGGTTTATGGATAACGGAAGCTGGAGCACTCGGAGCAATTATCGCATTTTTACTCGGCGGCC
TACTTGTCGTATTTGTTGGTTTAACATACGCAGAACTGTCCTCTGCACTTCCATTTGTCGGAGGAGAACATGTGTACACA
TACAAGGCAATGGGAAGAGTAACATCATTCATAGCCACTTGGGCAATTATTCTTGGTTATGTTTCAGTTATTGCTTTTGA
AGCAGTAGCCTTACCAACTGTTTTCGAGTACCTTGTCCCCAATTATAGTCAAGGATACCTCTATACAATTGCCGGTTGGG
ATGTCACATTAACTTGGGCTGGTGTGGGGATTATTGGTTCGGTATTGGTTGCATGGATTAATTATAGAGGAATTAAACTA
TCATCTATAATAAATTTCATCTTAACCATACTAATTCTCATTGCAGGAATCATGCTTATTACTGGAAGTACATTTAGCGG
TAATATGAGCAATATGAATCCGCTTTTTGAAACAGGAATGACAGGAATCATGACAGTTCTTATGATGACTTCTTTTATGT
TTGTTGGTTTTGATGTCATACCACAAGCTGCCGAAGAAATTAATCTACCAAATAAAAAAATCGGGCAATTACTAATCTTA
TCTGTAGTAGTAGCTGTAATTTGGTATATAGCGATAATTTTTGGTGTTTCTAGAATGTTAACTCCGTCAGAAATCAATGC
ATCCAATTTAGTTACAGCAGATGCGGTGGCAAAGGCTTTTGGAAATAGTGAAATGATGGGTAATTTTCTTGTCTTAGGTG
GTATCGGTGGGATATTGACAAGTTGGATCGGATTTTATGTTGGAGGTAGCAGGGCAATATATGCTTTAGCAAAGGCTGGA
ATGCTCCCTAAATCTCTAGGGCAATTACATCCTAAATATAATACTCCCCATAAAGCTATTTTGTTAATTGCAGTATTATC
GACGGCGGCTCCGCTTTTAGGAAGACCAGCTCTTGTTTGGTTAGTCAATGCAGGTGGTCTTGGACTTGTTGTTGCTTGGT
TAATGGTTACTATATCCTTTATAATATTGCGAAAGAAAGCACCAGAGATGCAACGACCCTTTCGCCTTCCTGGTGGAACT
ACGATTGGTTGGATAGCGACCATTATGGCTATTGGTGTTACGATTCTTTATCTTCCAGGTATGCCATCTGCGTTAATCTG
GCCCTATGAATGGCTTATCATCGGTACTTGGATTATATTAGGATTTGTTTTATACAATTACTCGATGAGGAAATATGGAA
AGAAAAATACAGATGATTACATGAAAAAAGAAGTGAATAAGAGCGCATAA

Upstream 100 bases:

>100_bases
TATAAGTGATGCTATTTTATTCGTTCAACATCAACTAGGTGTATCCCAAAATTATTAATAAATAAACCATGCTAAACCAA
CTATCATTAGGGGGAATTTG

Downstream 100 bases:

>100_bases
ACGAGTATCTGCCTCAATTTCAGCAAACTTCTTTTTATTATTAAAAAATGACAGCCGGTGATCCCCCCGTCTTGTGTATC
GGGAGATCGCCGGCTGTCAT

Product: cationic amino acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MNDSDKLLKSLGKKETFALAFGAMIGWGWVVTSGLWITEAGALGAIIAFLLGGLLVVFVGLTYAELSSALPFVGGEHVYT
YKAMGRVTSFIATWAIILGYVSVIAFEAVALPTVFEYLVPNYSQGYLYTIAGWDVTLTWAGVGIIGSVLVAWINYRGIKL
SSIINFILTILILIAGIMLITGSTFSGNMSNMNPLFETGMTGIMTVLMMTSFMFVGFDVIPQAAEEINLPNKKIGQLLIL
SVVVAVIWYIAIIFGVSRMLTPSEINASNLVTADAVAKAFGNSEMMGNFLVLGGIGGILTSWIGFYVGGSRAIYALAKAG
MLPKSLGQLHPKYNTPHKAILLIAVLSTAAPLLGRPALVWLVNAGGLGLVVAWLMVTISFIILRKKAPEMQRPFRLPGGT
TIGWIATIMAIGVTILYLPGMPSALIWPYEWLIIGTWIILGFVLYNYSMRKYGKKNTDDYMKKEVNKSA

Sequences:

>Translated_469_residues
MNDSDKLLKSLGKKETFALAFGAMIGWGWVVTSGLWITEAGALGAIIAFLLGGLLVVFVGLTYAELSSALPFVGGEHVYT
YKAMGRVTSFIATWAIILGYVSVIAFEAVALPTVFEYLVPNYSQGYLYTIAGWDVTLTWAGVGIIGSVLVAWINYRGIKL
SSIINFILTILILIAGIMLITGSTFSGNMSNMNPLFETGMTGIMTVLMMTSFMFVGFDVIPQAAEEINLPNKKIGQLLIL
SVVVAVIWYIAIIFGVSRMLTPSEINASNLVTADAVAKAFGNSEMMGNFLVLGGIGGILTSWIGFYVGGSRAIYALAKAG
MLPKSLGQLHPKYNTPHKAILLIAVLSTAAPLLGRPALVWLVNAGGLGLVVAWLMVTISFIILRKKAPEMQRPFRLPGGT
TIGWIATIMAIGVTILYLPGMPSALIWPYEWLIIGTWIILGFVLYNYSMRKYGKKNTDDYMKKEVNKSA
>Mature_469_residues
MNDSDKLLKSLGKKETFALAFGAMIGWGWVVTSGLWITEAGALGAIIAFLLGGLLVVFVGLTYAELSSALPFVGGEHVYT
YKAMGRVTSFIATWAIILGYVSVIAFEAVALPTVFEYLVPNYSQGYLYTIAGWDVTLTWAGVGIIGSVLVAWINYRGIKL
SSIINFILTILILIAGIMLITGSTFSGNMSNMNPLFETGMTGIMTVLMMTSFMFVGFDVIPQAAEEINLPNKKIGQLLIL
SVVVAVIWYIAIIFGVSRMLTPSEINASNLVTADAVAKAFGNSEMMGNFLVLGGIGGILTSWIGFYVGGSRAIYALAKAG
MLPKSLGQLHPKYNTPHKAILLIAVLSTAAPLLGRPALVWLVNAGGLGLVVAWLMVTISFIILRKKAPEMQRPFRLPGGT
TIGWIATIMAIGVTILYLPGMPSALIWPYEWLIIGTWIILGFVLYNYSMRKYGKKNTDDYMKKEVNKSA

Specific function: Unknown

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI181337167, Length=405, Percent_Identity=24.6913580246914, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI258614005, Length=440, Percent_Identity=25.6818181818182, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI258614003, Length=440, Percent_Identity=25.6818181818182, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI4507047, Length=428, Percent_Identity=25.7009345794392, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI114326544, Length=415, Percent_Identity=22.4096385542169, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI114326550, Length=415, Percent_Identity=22.4096385542169, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI258645169, Length=437, Percent_Identity=24.4851258581236, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI110347453, Length=353, Percent_Identity=24.0793201133144, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI7657683, Length=369, Percent_Identity=26.2872628726287, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI33286428, Length=416, Percent_Identity=24.7596153846154, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI9790235, Length=336, Percent_Identity=24.1071428571429, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI186910308, Length=415, Percent_Identity=24.0963855421687, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI186910306, Length=415, Percent_Identity=24.0963855421687, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI186910304, Length=415, Percent_Identity=24.0963855421687, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI87082250, Length=354, Percent_Identity=28.2485875706215, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1788480, Length=407, Percent_Identity=24.3243243243243, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789017, Length=457, Percent_Identity=24.0700218818381, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87081708, Length=401, Percent_Identity=22.4438902743142, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17532491, Length=399, Percent_Identity=26.0651629072682, Blast_Score=92, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17531343, Length=432, Percent_Identity=25.462962962963, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17533459, Length=408, Percent_Identity=24.0196078431373, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32566699, Length=318, Percent_Identity=23.5849056603774, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17540018, Length=428, Percent_Identity=23.3644859813084, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI32566695, Length=359, Percent_Identity=21.7270194986072, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI193208714, Length=359, Percent_Identity=21.7270194986072, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI221512776, Length=423, Percent_Identity=25.531914893617, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24666159, Length=423, Percent_Identity=25.531914893617, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24667468, Length=414, Percent_Identity=25.3623188405797, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24668806, Length=412, Percent_Identity=25.9708737864078, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21356285, Length=412, Percent_Identity=25.9708737864078, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24668802, Length=412, Percent_Identity=25.9708737864078, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI281366235, Length=405, Percent_Identity=26.9135802469136, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI116007820, Length=405, Percent_Identity=26.9135802469136, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI161077963, Length=395, Percent_Identity=24.5569620253165, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI116007818, Length=410, Percent_Identity=27.0731707317073, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI85725152, Length=410, Percent_Identity=27.0731707317073, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21357367, Length=418, Percent_Identity=22.7272727272727, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24651635, Length=405, Percent_Identity=22.7160493827161, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24651633, Length=405, Percent_Identity=22.7160493827161, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI45550968, Length=466, Percent_Identity=23.175965665236, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI19921172, Length=466, Percent_Identity=23.175965665236, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50706; Mature: 50706

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDSDKLLKSLGKKETFALAFGAMIGWGWVVTSGLWITEAGALGAIIAFLLGGLLVVFVG
CCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHH
LTYAELSSALPFVGGEHVYTYKAMGRVTSFIATWAIILGYVSVIAFEAVALPTVFEYLVP
HHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NYSQGYLYTIAGWDVTLTWAGVGIIGSVLVAWINYRGIKLSSIINFILTILILIAGIMLI
CCCCCEEEEEECCEEEEEHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHH
TGSTFSGNMSNMNPLFETGMTGIMTVLMMTSFMFVGFDVIPQAAEEINLPNKKIGQLLIL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
SVVVAVIWYIAIIFGVSRMLTPSEINASNLVTADAVAKAFGNSEMMGNFLVLGGIGGILT
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHCCEEEECCHHHHHH
SWIGFYVGGSRAIYALAKAGMLPKSLGQLHPKYNTPHKAILLIAVLSTAAPLLGRPALVW
HHHHHHCCCCHHHHHHHHCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEE
LVNAGGLGLVVAWLMVTISFIILRKKAPEMQRPFRLPGGTTIGWIATIMAIGVTILYLPG
EECCCCHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
MPSALIWPYEWLIIGTWIILGFVLYNYSMRKYGKKNTDDYMKKEVNKSA
CCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCC
>Mature Secondary Structure
MNDSDKLLKSLGKKETFALAFGAMIGWGWVVTSGLWITEAGALGAIIAFLLGGLLVVFVG
CCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHH
LTYAELSSALPFVGGEHVYTYKAMGRVTSFIATWAIILGYVSVIAFEAVALPTVFEYLVP
HHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NYSQGYLYTIAGWDVTLTWAGVGIIGSVLVAWINYRGIKLSSIINFILTILILIAGIMLI
CCCCCEEEEEECCEEEEEHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHH
TGSTFSGNMSNMNPLFETGMTGIMTVLMMTSFMFVGFDVIPQAAEEINLPNKKIGQLLIL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
SVVVAVIWYIAIIFGVSRMLTPSEINASNLVTADAVAKAFGNSEMMGNFLVLGGIGGILT
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHCCEEEECCHHHHHH
SWIGFYVGGSRAIYALAKAGMLPKSLGQLHPKYNTPHKAILLIAVLSTAAPLLGRPALVW
HHHHHHCCCCHHHHHHHHCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEE
LVNAGGLGLVVAWLMVTISFIILRKKAPEMQRPFRLPGGTTIGWIATIMAIGVTILYLPG
EECCCCHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
MPSALIWPYEWLIIGTWIILGFVLYNYSMRKYGKKNTDDYMKKEVNKSA
CCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]