Click here to switch to the map view.

The map label for this gene is ygjG [C]

Identifier: 23097945

GI number: 23097945

Start: 519652

End: 521001

Strand: Reverse

Name: ygjG [C]

Synonym: OB0490

Alternate gene names: 23097945

Gene position: 521001-519652 (Counterclockwise)

Preceding gene: 23097947

Following gene: 23097944

Centisome position: 14.35

GC content: 37.41

Gene sequence:

>1350_bases
ATGGAAGATTTATTTGAATTAGATAAAAAACATTTTATTCACCCTACGTCATCCATTATACAGCAACAAACAGATGGAGC
TAAGTCAATTATGGCTAAGGGTGATGGTATCTATGTTACAGATACCAATAACAAAGAATATATCGATGCAGTTTCTTCAC
TTTGGAATGTAAATATCGGACATGGAAGAACTGAATTAGCGGAAGTAGCATCAGAACAAATGAAAAAACTAGCTTTCAGT
TCTGCTTTTTCAACATTTAGTCATGAGCCAGCTATACGATTAGCAAAGAAAATTTCAGAACTTACTCCACAAGGATTAAA
TGCTGTCTTCTTCACTTCAGGCGGATCAGAGTCAAATGACTCCGCTGTAAAACTTTCACGTCATTACTGGAAAATACAAA
ACAAGGCTTCAAAAAGAAAAATCATTTCATTAAAAAGAGGATACCATGGAGTAGCTGCTGCCTCTACAAGCATAACTGGT
ATACCAGAATTTTGGGATATGGCTGGTCATTTGATGAATGACTTCTTACATGCAGAAACACCCTATCGTTCCACTACAGA
AAAAGCAATTGAATCGTTACAATCCATGATAGAACAAGAAACCGCAGATACAATTGCAGCAATTTTTGTAGAACCTGTAC
AAGGAGCTGGAGGTGTATTGATCCCGCCCGCAGATTATCTAGAAGCAGTAAGAGAAATTTGCGACTTCTATAATATCCTT
TTTATTGCTGATGAGGTAATCACTGGTTTTGGGAGAACTGGAACGATGTTTGGTATGGAAAATTGGAACGTTGTACCAGA
TGCAATGACTTTCGCTAAAGGTGTTACTAGTGGATATATTCCCATGGGGGGAGTTGTCGTATCCGATCATATTCACACTG
TATTAAAAGAAAAATCTAAAGGAACCCTCTTCCATGGATTTACCTATAGTGGTCATCCTACAGCTGCCGCGGTCGCATTA
AAAAATATAGAAATTATTGAAAAAGAGTCACTTGTCACTAATGCGAAGGAAAGAGGCTTAGAATTACAGAATGGTTTCCA
AAAGATCAAAAAAGAATCATCTATAGTTGGAGAAGTTAGAGCAATCGGATTAATAGGTGCTATCGAACTTATGCAGGATT
CTGCCACTGGTCAACCATTTACTCCGGATGTTGGTGTAACCCCCGCTGTTATTAATGCTTTACATGAACGAGGAGTTATA
TCTAGAGGCGTTACTTACGATGGTTCAAACATCTTATGCTTCGCTCCGCCGTTAATTATTACGAAACAAGAAGTTAATGA
ACTTATCTCCCGTATAAGTGATGCTATTTTATTCGTTCAACATCAACTAGGTGTATCCCAAAATTATTAA

Upstream 100 bases:

>100_bases
TTCACCCGTAAAGCACGAAATTAGATCAAGTACCAGTTATATCGACGGGTCAACTCTGTCTTTATGACTGGTTTTTGTAT
TTTAATAGGGAGGTTTTTTA

Downstream 100 bases:

>100_bases
TAAATAAACCATGCTAAACCAACTATCATTAGGGGGAATTTGATGAATGACTCGGATAAACTATTAAAATCACTAGGTAA
AAAGGAAACTTTTGCACTTG

Product: aminotransferase

Products: L-Glutamate; L-Glutamate 5-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MEDLFELDKKHFIHPTSSIIQQQTDGAKSIMAKGDGIYVTDTNNKEYIDAVSSLWNVNIGHGRTELAEVASEQMKKLAFS
SAFSTFSHEPAIRLAKKISELTPQGLNAVFFTSGGSESNDSAVKLSRHYWKIQNKASKRKIISLKRGYHGVAAASTSITG
IPEFWDMAGHLMNDFLHAETPYRSTTEKAIESLQSMIEQETADTIAAIFVEPVQGAGGVLIPPADYLEAVREICDFYNIL
FIADEVITGFGRTGTMFGMENWNVVPDAMTFAKGVTSGYIPMGGVVVSDHIHTVLKEKSKGTLFHGFTYSGHPTAAAVAL
KNIEIIEKESLVTNAKERGLELQNGFQKIKKESSIVGEVRAIGLIGAIELMQDSATGQPFTPDVGVTPAVINALHERGVI
SRGVTYDGSNILCFAPPLIITKQEVNELISRISDAILFVQHQLGVSQNY

Sequences:

>Translated_449_residues
MEDLFELDKKHFIHPTSSIIQQQTDGAKSIMAKGDGIYVTDTNNKEYIDAVSSLWNVNIGHGRTELAEVASEQMKKLAFS
SAFSTFSHEPAIRLAKKISELTPQGLNAVFFTSGGSESNDSAVKLSRHYWKIQNKASKRKIISLKRGYHGVAAASTSITG
IPEFWDMAGHLMNDFLHAETPYRSTTEKAIESLQSMIEQETADTIAAIFVEPVQGAGGVLIPPADYLEAVREICDFYNIL
FIADEVITGFGRTGTMFGMENWNVVPDAMTFAKGVTSGYIPMGGVVVSDHIHTVLKEKSKGTLFHGFTYSGHPTAAAVAL
KNIEIIEKESLVTNAKERGLELQNGFQKIKKESSIVGEVRAIGLIGAIELMQDSATGQPFTPDVGVTPAVINALHERGVI
SRGVTYDGSNILCFAPPLIITKQEVNELISRISDAILFVQHQLGVSQNY
>Mature_449_residues
MEDLFELDKKHFIHPTSSIIQQQTDGAKSIMAKGDGIYVTDTNNKEYIDAVSSLWNVNIGHGRTELAEVASEQMKKLAFS
SAFSTFSHEPAIRLAKKISELTPQGLNAVFFTSGGSESNDSAVKLSRHYWKIQNKASKRKIISLKRGYHGVAAASTSITG
IPEFWDMAGHLMNDFLHAETPYRSTTEKAIESLQSMIEQETADTIAAIFVEPVQGAGGVLIPPADYLEAVREICDFYNIL
FIADEVITGFGRTGTMFGMENWNVVPDAMTFAKGVTSGYIPMGGVVVSDHIHTVLKEKSKGTLFHGFTYSGHPTAAAVAL
KNIEIIEKESLVTNAKERGLELQNGFQKIKKESSIVGEVRAIGLIGAIELMQDSATGQPFTPDVGVTPAVINALHERGVI
SRGVTYDGSNILCFAPPLIITKQEVNELISRISDAILFVQHQLGVSQNY

Specific function: Unknown

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI37574042, Length=461, Percent_Identity=29.2841648590022, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI226442705, Length=461, Percent_Identity=28.8503253796095, Blast_Score=172, Evalue=7e-43,
Organism=Homo sapiens, GI13994255, Length=466, Percent_Identity=27.0386266094421, Blast_Score=172, Evalue=8e-43,
Organism=Homo sapiens, GI4557809, Length=441, Percent_Identity=29.2517006802721, Blast_Score=169, Evalue=7e-42,
Organism=Homo sapiens, GI24119277, Length=427, Percent_Identity=29.5081967213115, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI226442709, Length=404, Percent_Identity=29.4554455445545, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI284507298, Length=325, Percent_Identity=31.0769230769231, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI188536080, Length=447, Percent_Identity=21.7002237136465, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI38679950, Length=447, Percent_Identity=21.7002237136465, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI38679946, Length=447, Percent_Identity=21.7002237136465, Blast_Score=91, Evalue=3e-18,
Organism=Escherichia coli, GI145693181, Length=401, Percent_Identity=29.925187032419, Blast_Score=188, Evalue=5e-49,
Organism=Escherichia coli, GI1788044, Length=410, Percent_Identity=30.9756097560976, Blast_Score=184, Evalue=8e-48,
Organism=Escherichia coli, GI1789759, Length=411, Percent_Identity=29.1970802919708, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI1789016, Length=416, Percent_Identity=30.7692307692308, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1786991, Length=441, Percent_Identity=26.0770975056689, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI1787560, Length=413, Percent_Identity=29.5399515738499, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1786349, Length=352, Percent_Identity=26.1363636363636, Blast_Score=103, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI32564660, Length=440, Percent_Identity=30, Blast_Score=171, Evalue=7e-43,
Organism=Caenorhabditis elegans, GI25144271, Length=400, Percent_Identity=29.25, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI71992977, Length=426, Percent_Identity=25.1173708920188, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI25144274, Length=287, Percent_Identity=29.616724738676, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17541228, Length=460, Percent_Identity=24.1304347826087, Blast_Score=112, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6324386, Length=499, Percent_Identity=28.2565130260521, Blast_Score=159, Evalue=9e-40,
Organism=Saccharomyces cerevisiae, GI6323470, Length=413, Percent_Identity=26.8765133171913, Blast_Score=154, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6324432, Length=406, Percent_Identity=27.0935960591133, Blast_Score=130, Evalue=6e-31,
Organism=Saccharomyces cerevisiae, GI6321456, Length=285, Percent_Identity=24.9122807017544, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21357415, Length=409, Percent_Identity=29.5843520782396, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI161085790, Length=441, Percent_Identity=28.3446712018141, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI21356575, Length=418, Percent_Identity=27.511961722488, Blast_Score=158, Evalue=8e-39,
Organism=Drosophila melanogaster, GI28574759, Length=439, Percent_Identity=28.4738041002278, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI281366494, Length=462, Percent_Identity=24.8917748917749, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24667139, Length=462, Percent_Identity=24.8917748917749, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24667143, Length=462, Percent_Identity=24.8917748917749, Blast_Score=96, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.13 [C]

Molecular weight: Translated: 48972; Mature: 48972

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDLFELDKKHFIHPTSSIIQQQTDGAKSIMAKGDGIYVTDTNNKEYIDAVSSLWNVNIG
CCHHHHHHHHHCCCCHHHHHHHHCCCHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCC
HGRTELAEVASEQMKKLAFSSAFSTFSHEPAIRLAKKISELTPQGLNAVFFTSGGSESND
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCC
SAVKLSRHYWKIQNKASKRKIISLKRGYHGVAAASTSITGIPEFWDMAGHLMNDFLHAET
HHHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHCCC
PYRSTTEKAIESLQSMIEQETADTIAAIFVEPVQGAGGVLIPPADYLEAVREICDFYNIL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHH
FIADEVITGFGRTGTMFGMENWNVVPDAMTFAKGVTSGYIPMGGVVVSDHIHTVLKEKSK
HHHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHCCC
GTLFHGFTYSGHPTAAAVALKNIEIIEKESLVTNAKERGLELQNGFQKIKKESSIVGEVR
CCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
AIGLIGAIELMQDSATGQPFTPDVGVTPAVINALHERGVISRGVTYDGSNILCFAPPLII
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCHHCCCEECCCEEEEECCCEEE
TKQEVNELISRISDAILFVQHQLGVSQNY
EHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MEDLFELDKKHFIHPTSSIIQQQTDGAKSIMAKGDGIYVTDTNNKEYIDAVSSLWNVNIG
CCHHHHHHHHHCCCCHHHHHHHHCCCHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCC
HGRTELAEVASEQMKKLAFSSAFSTFSHEPAIRLAKKISELTPQGLNAVFFTSGGSESND
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCC
SAVKLSRHYWKIQNKASKRKIISLKRGYHGVAAASTSITGIPEFWDMAGHLMNDFLHAET
HHHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHCCC
PYRSTTEKAIESLQSMIEQETADTIAAIFVEPVQGAGGVLIPPADYLEAVREICDFYNIL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHH
FIADEVITGFGRTGTMFGMENWNVVPDAMTFAKGVTSGYIPMGGVVVSDHIHTVLKEKSK
HHHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHCCC
GTLFHGFTYSGHPTAAAVALKNIEIIEKESLVTNAKERGLELQNGFQKIKKESSIVGEVR
CCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
AIGLIGAIELMQDSATGQPFTPDVGVTPAVINALHERGVISRGVTYDGSNILCFAPPLII
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCHHCCCEECCCEEEEECCCEEE
TKQEVNELISRISDAILFVQHQLGVSQNY
EHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; Ornithine [C]

Specific reaction: 2-Oxoglutarate + Ornithine --> L-Glutamate + L-Glutamate 5-semialdehyde [C]

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]