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The map label for this gene is folB [H]

Identifier: 23097541

GI number: 23097541

Start: 88301

End: 88666

Strand: Direct

Name: folB [H]

Synonym: OB0086

Alternate gene names: 23097541

Gene position: 88301-88666 (Clockwise)

Preceding gene: 23097540

Following gene: 23097542

Centisome position: 2.43

GC content: 35.52

Gene sequence:

>366_bases
ATGGATAAAATCATTATAAAACAAATGCAATTTTATGGTTATCATGGACTTTTTCCAGAAGAAAATAAACTAGGACAACG
GTTTAATGTAGATCTTGAATTACATGTTCCTTTAGATAAGGCGGGAATATCGGATGACATGAATGAGTCCATCCATTATG
GGCAGGCTTATGAAACTGTAAAAAAAGTCGTTGAAGGTCCTTCATATAATCTAATTGAAGCAGTAGCTGAGGGAATCTCT
AAGGAGTTATTTGCATCCTTTTCATTATTGAATGCTTGTTTAGTGAGAGTAGTAAAACCAGACCCGCCAATTCCGGGGCA
TTATCAATCTGTTGCTGTAGAAATTTATAGGGAGAGGGAAAAATGA

Upstream 100 bases:

>100_bases
TACAGCAAGGAGCTCATATAGTACGAGTGCATAATGTACATATCAATGCAGAAGCTGCCAAGGTCGCAGATGCTATCTAT
GGGAAAAGGAGTCTTTAGGA

Downstream 100 bases:

>100_bases
ATGAAGCTTATGTAGCCTTAGGCACAAATATTGAACCGCGAGAAAACTTTATTAATCAAGCACTGCAATTTTTGGATGAC
CACCCAAACATAACCATTAA

Product: dihydroneopterin aldolase

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 121; Mature: 121

Protein sequence:

>121_residues
MDKIIIKQMQFYGYHGLFPEENKLGQRFNVDLELHVPLDKAGISDDMNESIHYGQAYETVKKVVEGPSYNLIEAVAEGIS
KELFASFSLLNACLVRVVKPDPPIPGHYQSVAVEIYREREK

Sequences:

>Translated_121_residues
MDKIIIKQMQFYGYHGLFPEENKLGQRFNVDLELHVPLDKAGISDDMNESIHYGQAYETVKKVVEGPSYNLIEAVAEGIS
KELFASFSLLNACLVRVVKPDPPIPGHYQSVAVEIYREREK
>Mature_121_residues
MDKIIIKQMQFYGYHGLFPEENKLGQRFNVDLELHVPLDKAGISDDMNESIHYGQAYETVKKVVEGPSYNLIEAVAEGIS
KELFASFSLLNACLVRVVKPDPPIPGHYQSVAVEIYREREK

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 13756; Mature: 13756

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKIIIKQMQFYGYHGLFPEENKLGQRFNVDLELHVPLDKAGISDDMNESIHYGQAYETV
CCHHHHHHHHHHCCCCCCCCCCCCCCEECCCEEEECCCCCCCCCCCCCHHHCCCHHHHHH
KKVVEGPSYNLIEAVAEGISKELFASFSLLNACLVRVVKPDPPIPGHYQSVAVEIYRERE
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCC
K
C
>Mature Secondary Structure
MDKIIIKQMQFYGYHGLFPEENKLGQRFNVDLELHVPLDKAGISDDMNESIHYGQAYETV
CCHHHHHHHHHHCCCCCCCCCCCCCCEECCCEEEECCCCCCCCCCCCCHHHCCCHHHHHH
KKVVEGPSYNLIEAVAEGISKELFASFSLLNACLVRVVKPDPPIPGHYQSVAVEIYRERE
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]