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The map label for this gene is yabD [H]

Identifier: 23097502

GI number: 23097502

Start: 47567

End: 48337

Strand: Direct

Name: yabD [H]

Synonym: OB0047

Alternate gene names: 23097502

Gene position: 47567-48337 (Clockwise)

Preceding gene: 23097501

Following gene: 23097503

Centisome position: 1.31

GC content: 37.61

Gene sequence:

>771_bases
ATGTTATTTGATACACATGTACATTTAAATGCGAGACAATTTAAGGATGATCGTGAAGAAACTATTCAGCGAGCATACGA
TGCCGGCGTTGAAAATATGGTTGTTGTCGGATTCGATAGAGAGACAATACCTTTAGCAATAGAGATTGCAGAAAGCCATC
CGGCAATTTATGCCGCAGTAGGGTGGCATCCTGTAGATGCTATTGATATGACAGAAGAAGATCTTAGCTGGATCGAGCAA
TTGAGTTCACATCCAAAAGTGGTTGCTATTGGTGAGATGGGACTGGACTATCATTGGGATAAATCACCAAAGGAGATTCA
AAAAGAAGTATTTCGAAAACAAATAGCACTTGCGAAAAAAGTAAACATGCCGATAATCATTCATAATCGAGAAGCTACAG
AAGATATTATCAAAATTCTACAAGAGGAAAATGCGAAAGAAATAGGCGGAATTATGCATTGTTACAATGATTCAGTCGAG
TATGTACAGGATTGCTTGGACATGAATTTCTATATTTCTTTAGGTGGACCAGTAACCTTTAAGAACGCACCGCTTCCGAA
AGAAGTTGCAAAAGAAGTTCCTTTAGACCGTTTATTAATTGAAACAGATGCACCATTTCTAGCCCCTCATCCAAATCGAG
GAAAAAGAAATGAACCTGCATACGTTCGACTAGTCGCTGAACAAATTGCTGCTTTAAGAGAAATGAGTGTAGAAGAAATT
GGAGAAATTACTACAAAGAATGCGCGACGTTTTTTTAATATAAACGAATAA

Upstream 100 bases:

>100_bases
CTATAAGCTAAATCGGATCGAGCTATAATGGGGTGACACTTCCTAGATACCCGGATTATAGCTCGGTTTTTTATTTTAAA
AAAGAAAAGGATGAACAAGT

Downstream 100 bases:

>100_bases
AAATTACGCGATATTGTCATAAACGAGCTAAAAAATGGAAAAAATTTGGGGGATAAACGGACTGTTTATCTCCTTTTTTT
ACAATTTGATAACAAGCTTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MLFDTHVHLNARQFKDDREETIQRAYDAGVENMVVVGFDRETIPLAIEIAESHPAIYAAVGWHPVDAIDMTEEDLSWIEQ
LSSHPKVVAIGEMGLDYHWDKSPKEIQKEVFRKQIALAKKVNMPIIIHNREATEDIIKILQEENAKEIGGIMHCYNDSVE
YVQDCLDMNFYISLGGPVTFKNAPLPKEVAKEVPLDRLLIETDAPFLAPHPNRGKRNEPAYVRLVAEQIAALREMSVEEI
GEITTKNARRFFNINE

Sequences:

>Translated_256_residues
MLFDTHVHLNARQFKDDREETIQRAYDAGVENMVVVGFDRETIPLAIEIAESHPAIYAAVGWHPVDAIDMTEEDLSWIEQ
LSSHPKVVAIGEMGLDYHWDKSPKEIQKEVFRKQIALAKKVNMPIIIHNREATEDIIKILQEENAKEIGGIMHCYNDSVE
YVQDCLDMNFYISLGGPVTFKNAPLPKEVAKEVPLDRLLIETDAPFLAPHPNRGKRNEPAYVRLVAEQIAALREMSVEEI
GEITTKNARRFFNINE
>Mature_256_residues
MLFDTHVHLNARQFKDDREETIQRAYDAGVENMVVVGFDRETIPLAIEIAESHPAIYAAVGWHPVDAIDMTEEDLSWIEQ
LSSHPKVVAIGEMGLDYHWDKSPKEIQKEVFRKQIALAKKVNMPIIIHNREATEDIIKILQEENAKEIGGIMHCYNDSVE
YVQDCLDMNFYISLGGPVTFKNAPLPKEVAKEVPLDRLLIETDAPFLAPHPNRGKRNEPAYVRLVAEQIAALREMSVEEI
GEITTKNARRFFNINE

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI14042943, Length=275, Percent_Identity=26.1818181818182, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI110349730, Length=266, Percent_Identity=29.6992481203008, Blast_Score=111, Evalue=6e-25,
Organism=Homo sapiens, GI110349734, Length=266, Percent_Identity=29.6992481203008, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI226061853, Length=272, Percent_Identity=29.4117647058824, Blast_Score=108, Evalue=3e-24,
Organism=Homo sapiens, GI226061614, Length=253, Percent_Identity=28.0632411067194, Blast_Score=104, Evalue=6e-23,
Organism=Homo sapiens, GI225903439, Length=248, Percent_Identity=26.2096774193548, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI225903424, Length=157, Percent_Identity=33.1210191082803, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI226061595, Length=229, Percent_Identity=27.0742358078603, Blast_Score=81, Evalue=8e-16,
Organism=Escherichia coli, GI1787342, Length=262, Percent_Identity=37.4045801526718, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI48994985, Length=259, Percent_Identity=32.046332046332, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI87082439, Length=255, Percent_Identity=30.1960784313725, Blast_Score=134, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI17559024, Length=280, Percent_Identity=31.0714285714286, Blast_Score=151, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI71980746, Length=263, Percent_Identity=27.7566539923954, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17543026, Length=185, Percent_Identity=31.8918918918919, Blast_Score=97, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17565396, Length=227, Percent_Identity=32.5991189427313, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24648690, Length=288, Percent_Identity=32.2916666666667, Blast_Score=139, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24586117, Length=271, Percent_Identity=28.0442804428044, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI221330018, Length=271, Percent_Identity=28.0442804428044, Blast_Score=102, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29204; Mature: 29204

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS01137 TATD_1 ; PS01090 TATD_2 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFDTHVHLNARQFKDDREETIQRAYDAGVENMVVVGFDRETIPLAIEIAESHPAIYAAV
CEEECEEECCHHHHCCHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEECCCCEEEEEE
GWHPVDAIDMTEEDLSWIEQLSSHPKVVAIGEMGLDYHWDKSPKEIQKEVFRKQIALAKK
CCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VNMPIIIHNREATEDIIKILQEENAKEIGGIMHCYNDSVEYVQDCLDMNFYISLGGPVTF
CCCCEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCEEE
KNAPLPKEVAKEVPLDRLLIETDAPFLAPHPNRGKRNEPAYVRLVAEQIAALREMSVEEI
CCCCCCHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHH
GEITTKNARRFFNINE
HHHHHCCCCEEECCCC
>Mature Secondary Structure
MLFDTHVHLNARQFKDDREETIQRAYDAGVENMVVVGFDRETIPLAIEIAESHPAIYAAV
CEEECEEECCHHHHCCHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEECCCCEEEEEE
GWHPVDAIDMTEEDLSWIEQLSSHPKVVAIGEMGLDYHWDKSPKEIQKEVFRKQIALAKK
CCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VNMPIIIHNREATEDIIKILQEENAKEIGGIMHCYNDSVEYVQDCLDMNFYISLGGPVTF
CCCCEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCEEE
KNAPLPKEVAKEVPLDRLLIETDAPFLAPHPNRGKRNEPAYVRLVAEQIAALREMSVEEI
CCCCCCHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHH
GEITTKNARRFFNINE
HHHHHCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]