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The map label for this gene is dck [H]

Identifier: 23097470

GI number: 23097470

Start: 18952

End: 19638

Strand: Reverse

Name: dck [H]

Synonym: OB0015

Alternate gene names: 23097470

Gene position: 19638-18952 (Counterclockwise)

Preceding gene: 23097471

Following gene: 23097464

Centisome position: 0.54

GC content: 34.5

Gene sequence:

>687_bases
ATGAACTTACGTGAAAAATACCAAATTCCAAATGACAGCATTATAACCATTGCAGGAACAGTTGGAGTTGGAAAATCAAC
AATGACCAATGCATTAGCAGAGGCATTACACTTTAAAACTTCATTTGAAAAAGTGGATTCTAATCCCTATTTAAGTGATT
TTTATAATGACTTTGAACGTTGGAGCTTCCATTTGCAAATCTATTTCTTAGCAGAACGCTTTAAAGAGCAGAAAAAGATT
TTTGAATATGGTGGCGGATTTATTCAAGATCGTTCTATTTATGAAGATACCGGTATTTTTGCTAAAATGCATTACGATAA
TGGAACCATGAATCCAACTGATTACGATACGTACAAAAGCTTATTTGATGCGATGGTAATGACGCCGTATTTTCCACATC
CGGATTTACTCATATATCTAGAAGGATCTTTTGATGAGATCGTTTCACGAATCAAAAGTCGTGGGCGTGATATGGAGAAG
AATACTCCAATTGAGTATTGGGAAGAAATGTATCGCCGATATAGTGATTGGATAGATAACTTCAATGCTTGTCCGGTGTT
ACGAATTAACATCTCGGATTATGATTTAATGAAAGAAGATGATTCCCTAGCGTTAATTTTAGAAAAGATAGGGCGCTCCA
TTCAACTTTCTAGAAAATATAAAAAAGGTGAAATTATCACCAACTAA

Upstream 100 bases:

>100_bases
ATCAAGATCATTTAGAACAAATCATTGGTGATGTCGAAAGCCTTATTAACGAACAATGTAGGGCTTTACCGTCTAACTAA
TCAAAAAAGGGAGTTACAAA

Downstream 100 bases:

>100_bases
TAAAGAGGTGGGTCGGGACATAACCAAATTATTTGGTCAAAAGGCGGATGATAGATAAAATAAGCGTAAGAAATATACGG
AGACTCCTTGAAAATCAAAA

Product: deoxypurine kinase subunit

Products: NA

Alternate protein names: dAK/dCK [H]

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MNLREKYQIPNDSIITIAGTVGVGKSTMTNALAEALHFKTSFEKVDSNPYLSDFYNDFERWSFHLQIYFLAERFKEQKKI
FEYGGGFIQDRSIYEDTGIFAKMHYDNGTMNPTDYDTYKSLFDAMVMTPYFPHPDLLIYLEGSFDEIVSRIKSRGRDMEK
NTPIEYWEEMYRRYSDWIDNFNACPVLRINISDYDLMKEDDSLALILEKIGRSIQLSRKYKKGEIITN

Sequences:

>Translated_228_residues
MNLREKYQIPNDSIITIAGTVGVGKSTMTNALAEALHFKTSFEKVDSNPYLSDFYNDFERWSFHLQIYFLAERFKEQKKI
FEYGGGFIQDRSIYEDTGIFAKMHYDNGTMNPTDYDTYKSLFDAMVMTPYFPHPDLLIYLEGSFDEIVSRIKSRGRDMEK
NTPIEYWEEMYRRYSDWIDNFNACPVLRINISDYDLMKEDDSLALILEKIGRSIQLSRKYKKGEIITN
>Mature_228_residues
MNLREKYQIPNDSIITIAGTVGVGKSTMTNALAEALHFKTSFEKVDSNPYLSDFYNDFERWSFHLQIYFLAERFKEQKKI
FEYGGGFIQDRSIYEDTGIFAKMHYDNGTMNPTDYDTYKSLFDAMVMTPYFPHPDLLIYLEGSFDEIVSRIKSRGRDMEK
NTPIEYWEEMYRRYSDWIDNFNACPVLRINISDYDLMKEDDSLALILEKIGRSIQLSRKYKKGEIITN

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dATP AND dCTP for DNA metabolism. The phosphate acceptor specificity is strict toward deoxyadenosine (dAdo) and deoxycytidine (dCyd). The specificity toward the sugar moiety of the n

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

Organism=Homo sapiens, GI4503269, Length=222, Percent_Identity=25.6756756756757, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.74; =2.7.1.76 [H]

Molecular weight: Translated: 26887; Mature: 26887

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLREKYQIPNDSIITIAGTVGVGKSTMTNALAEALHFKTSFEKVDSNPYLSDFYNDFER
CCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
WSFHLQIYFLAERFKEQKKIFEYGGGFIQDRSIYEDTGIFAKMHYDNGTMNPTDYDTYKS
HEEEEEEHHHHHHHHHHHHHHHHCCCEEECCCEECCCCEEEEEEECCCCCCCCCHHHHHH
LFDAMVMTPYFPHPDLLIYLEGSFDEIVSRIKSRGRDMEKNTPIEYWEEMYRRYSDWIDN
HHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCC
FNACPVLRINISDYDLMKEDDSLALILEKIGRSIQLSRKYKKGEIITN
CCCCEEEEEECCCCHHHCCCCHHHHHHHHHCCCEEEHHHHCCCCCCCC
>Mature Secondary Structure
MNLREKYQIPNDSIITIAGTVGVGKSTMTNALAEALHFKTSFEKVDSNPYLSDFYNDFER
CCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
WSFHLQIYFLAERFKEQKKIFEYGGGFIQDRSIYEDTGIFAKMHYDNGTMNPTDYDTYKS
HEEEEEEHHHHHHHHHHHHHHHHCCCEEECCCEECCCCEEEEEEECCCCCCCCCHHHHHH
LFDAMVMTPYFPHPDLLIYLEGSFDEIVSRIKSRGRDMEKNTPIEYWEEMYRRYSDWIDN
HHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCC
FNACPVLRINISDYDLMKEDDSLALILEKIGRSIQLSRKYKKGEIITN
CCCCEEEEEECCCCHHHCCCCHHHHHHHHHCCCEEEHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]