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The map label for this gene is dgk [H]

Identifier: 23097471

GI number: 23097471

Start: 19659

End: 20309

Strand: Reverse

Name: dgk [H]

Synonym: OB0016

Alternate gene names: 23097471

Gene position: 20309-19659 (Counterclockwise)

Preceding gene: 23097474

Following gene: 23097470

Centisome position: 0.56

GC content: 34.25

Gene sequence:

>651_bases
ATGACAGATATGCCTTTTATTGCCATCGAAGGACCGATTGGTATTGGAAAAACATCCTTAGCAAAAAAACTATCCGACCA
CTTTGAATTTCATTTACTTAAGGAAATTGTCGAAGAAAATCCATTTCTAGGAAAATTCTACGAGAATATCAGTGAATGGA
GTTTCCAAACGGAAATGTTCTTTCTATGCAATCGTTTCAAACAACTCGAAGATATTAATAAAGACTATTTACAACAAGAG
CAGCCAGTGATTGCTGATTACCATATAACAAAAAATATGATCTTTGCGAAGCGTACATTACAACAAGATAAATTAGAGAA
ATACGAAAAGATCTATCAAATATTAACAGAGGACATACCAACACCAAATATACTTATTTATATTCATGCAGATTTAGATA
CGATTCTAAAACGAATTCGTATGCGTGGACGTGAGGTTGAGCAGCATATTGACCCAGAATACTTACGACAGCTTTCTGCT
GATTATGAGGCATTTATGTTGGAATTTGAACGTACACATCCTCATATCCCTGTATTGCGTATTAATGGAGATCAAATGGA
CTTTGTTCAATATCAAGATCATTTAGAACAAATCATTGGTGATGTCGAAAGCCTTATTAACGAACAATGTAGGGCTTTAC
CGTCTAACTAA

Upstream 100 bases:

>100_bases
TCAAGAAATGTATACTATTTGTTGTCTTGTAGTAGATAATGTCGATTTATGGTAGAATAAGTAGCGTGTTTTATGTCTGT
GGGAAATAGGAGGGAAACCA

Downstream 100 bases:

>100_bases
TCAAAAAAGGGAGTTACAAAATGAACTTACGTGAAAAATACCAAATTCCAAATGACAGCATTATAACCATTGCAGGAACA
GTTGGAGTTGGAAAATCAAC

Product: deoxypurine kinase subunit

Products: NA

Alternate protein names: DGUO kinase; dGK [H]

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MTDMPFIAIEGPIGIGKTSLAKKLSDHFEFHLLKEIVEENPFLGKFYENISEWSFQTEMFFLCNRFKQLEDINKDYLQQE
QPVIADYHITKNMIFAKRTLQQDKLEKYEKIYQILTEDIPTPNILIYIHADLDTILKRIRMRGREVEQHIDPEYLRQLSA
DYEAFMLEFERTHPHIPVLRINGDQMDFVQYQDHLEQIIGDVESLINEQCRALPSN

Sequences:

>Translated_216_residues
MTDMPFIAIEGPIGIGKTSLAKKLSDHFEFHLLKEIVEENPFLGKFYENISEWSFQTEMFFLCNRFKQLEDINKDYLQQE
QPVIADYHITKNMIFAKRTLQQDKLEKYEKIYQILTEDIPTPNILIYIHADLDTILKRIRMRGREVEQHIDPEYLRQLSA
DYEAFMLEFERTHPHIPVLRINGDQMDFVQYQDHLEQIIGDVESLINEQCRALPSN
>Mature_215_residues
TDMPFIAIEGPIGIGKTSLAKKLSDHFEFHLLKEIVEENPFLGKFYENISEWSFQTEMFFLCNRFKQLEDINKDYLQQEQ
PVIADYHITKNMIFAKRTLQQDKLEKYEKIYQILTEDIPTPNILIYIHADLDTILKRIRMRGREVEQHIDPEYLRQLSAD
YEAFMLEFERTHPHIPVLRINGDQMDFVQYQDHLEQIIGDVESLINEQCRALPSN

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dGTP for DNA metabolism. Highly specific toward deoxyguanosine (dGuo) and deoxyinosine (dIno). Only marginal activity is observed with guanosine. UTP is slightly more efficient as ph

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.113 [H]

Molecular weight: Translated: 25698; Mature: 25567

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDMPFIAIEGPIGIGKTSLAKKLSDHFEFHLLKEIVEENPFLGKFYENISEWSFQTEMF
CCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
FLCNRFKQLEDINKDYLQQEQPVIADYHITKNMIFAKRTLQQDKLEKYEKIYQILTEDIP
HHHHHHHHHHHCCHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TPNILIYIHADLDTILKRIRMRGREVEQHIDPEYLRQLSADYEAFMLEFERTHPHIPVLR
CCCEEEEEECCHHHHHHHHHHCCHHHHHCCCHHHHHHHHCCHHHHHHHHHCCCCCCEEEE
INGDQMDFVQYQDHLEQIIGDVESLINEQCRALPSN
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TDMPFIAIEGPIGIGKTSLAKKLSDHFEFHLLKEIVEENPFLGKFYENISEWSFQTEMF
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
FLCNRFKQLEDINKDYLQQEQPVIADYHITKNMIFAKRTLQQDKLEKYEKIYQILTEDIP
HHHHHHHHHHHCCHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TPNILIYIHADLDTILKRIRMRGREVEQHIDPEYLRQLSADYEAFMLEFERTHPHIPVLR
CCCEEEEEECCHHHHHHHHHHCCHHHHHCCCHHHHHHHHCCHHHHHHHHHCCCCCCEEEE
INGDQMDFVQYQDHLEQIIGDVESLINEQCRALPSN
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]