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The map label for this gene is glnP [H]

Identifier: 22127991

GI number: 22127991

Start: 4576991

End: 4577800

Strand: Reverse

Name: glnP [H]

Synonym: y4123

Alternate gene names: 22127991

Gene position: 4577800-4576991 (Counterclockwise)

Preceding gene: 22127992

Following gene: 22127989

Centisome position: 99.5

GC content: 50.25

Gene sequence:

>810_bases
TTGAGGCTTGGGGTATGTGGCGTCAACAGCGAACCGTCGTCCGAGGGCACTGAGATGGATTTTACCATTATCGTTGATAA
CTGGCGTTATCTGCTGTGGGGGACTTTCCCTGATGGCCCTCTGGGAGGGGCGGCATTGACCGTGGTGATCAGTATCATGG
CTGGGGTAGCCTCAGCCGTATTAGGCACTGTGTTGGGCGTGGCATTGGCGATGTCCCGTGGTGTCTGGGCGGGAATATTG
GCCGCTGTTTTGGGCTTATTCCGTGCGATTCCGGTGATTATGTTGATTTTTTGGACGTATTTCCTGCTACCGATCGTTTT
TGGTGTGGATATACCTGAAATCACCACTGTGGTGTGTGCACTGGCGCTGATTGCTTCTGCTTATCTGGCTCATGCGGTAA
AGGCCGGGATAATGGCTATTGGTGCCGGGCAGTGGCAAGCGGGGCTGTCGTTAGGTTTTAATCGCTGGCAGACCCTGTGG
TTTATTGTATTGCCACAAGCGCTGCGCATGATGGTGCCGTCCTTTATTAATCAATGGATATCATTGATTAAAGATACATC
GCTGGCTTATATCGTCGGAGTGAATGAGCTGACCTTTTTGGCTACACAGGTTAATAACCGCAGTATGGTTTACCCGATGG
AAGTCTTTCTGTTTGTGGCATTGGTCTATTTTGTTTTATGTCTGGCGCTGGATCTACTGGCTAACGGCCTTAATCGCCGC
TTTAGCCCACAGCATGCCATTAAAAACCAAAGCTCCATGGCACGTTCATGGCGCTGGTGGTGTAACAAGCTAACACTGCA
ATCGAGTTAA

Upstream 100 bases:

>100_bases
GAACTCTCCTATGCTTCCCGGCAGGTTGAAACTGAAACATTACGGACGTTTCAGGCATTCGGGGTTGCAACCCTATTGTA
TATTTTCATCATCGCGCTAA

Downstream 100 bases:

>100_bases
TTGATTATAGGCAGGCTAATTCATTACAGGTAAATTAATCGCGGGTGATATGCCAGCCTCTTTCCTTCCACAAATGAGGC
AGTTGCTGAATATCCGTGAA

Product: amino acid ABC transport system permease

Products: ADP; phosphate; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MRLGVCGVNSEPSSEGTEMDFTIIVDNWRYLLWGTFPDGPLGGAALTVVISIMAGVASAVLGTVLGVALAMSRGVWAGIL
AAVLGLFRAIPVIMLIFWTYFLLPIVFGVDIPEITTVVCALALIASAYLAHAVKAGIMAIGAGQWQAGLSLGFNRWQTLW
FIVLPQALRMMVPSFINQWISLIKDTSLAYIVGVNELTFLATQVNNRSMVYPMEVFLFVALVYFVLCLALDLLANGLNRR
FSPQHAIKNQSSMARSWRWWCNKLTLQSS

Sequences:

>Translated_269_residues
MRLGVCGVNSEPSSEGTEMDFTIIVDNWRYLLWGTFPDGPLGGAALTVVISIMAGVASAVLGTVLGVALAMSRGVWAGIL
AAVLGLFRAIPVIMLIFWTYFLLPIVFGVDIPEITTVVCALALIASAYLAHAVKAGIMAIGAGQWQAGLSLGFNRWQTLW
FIVLPQALRMMVPSFINQWISLIKDTSLAYIVGVNELTFLATQVNNRSMVYPMEVFLFVALVYFVLCLALDLLANGLNRR
FSPQHAIKNQSSMARSWRWWCNKLTLQSS
>Mature_269_residues
MRLGVCGVNSEPSSEGTEMDFTIIVDNWRYLLWGTFPDGPLGGAALTVVISIMAGVASAVLGTVLGVALAMSRGVWAGIL
AAVLGLFRAIPVIMLIFWTYFLLPIVFGVDIPEITTVVCALALIASAYLAHAVKAGIMAIGAGQWQAGLSLGFNRWQTLW
FIVLPQALRMMVPSFINQWISLIKDTSLAYIVGVNELTFLATQVNNRSMVYPMEVFLFVALVYFVLCLALDLLANGLNRR
FSPQHAIKNQSSMARSWRWWCNKLTLQSS

Specific function: Part of the ABC transporter complex glnHMPQ involved in glutamine transport. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786873, Length=231, Percent_Identity=34.6320346320346, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1787030, Length=204, Percent_Identity=31.8627450980392, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788226, Length=210, Percent_Identity=33.8095238095238, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI87082239, Length=209, Percent_Identity=31.1004784688995, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1787087, Length=225, Percent_Identity=25.7777777777778, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI48994930, Length=136, Percent_Identity=33.8235294117647, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788646, Length=227, Percent_Identity=25.9911894273128, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786874, Length=232, Percent_Identity=23.7068965517241, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788645, Length=228, Percent_Identity=26.3157894736842, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29466; Mature: 29466

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLGVCGVNSEPSSEGTEMDFTIIVDNWRYLLWGTFPDGPLGGAALTVVISIMAGVASAV
CCEEECCCCCCCCCCCCCEEEEEEEECCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
LGTVLGVALAMSRGVWAGILAAVLGLFRAIPVIMLIFWTYFLLPIVFGVDIPEITTVVCA
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LALIASAYLAHAVKAGIMAIGAGQWQAGLSLGFNRWQTLWFIVLPQALRMMVPSFINQWI
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLIKDTSLAYIVGVNELTFLATQVNNRSMVYPMEVFLFVALVYFVLCLALDLLANGLNRR
HHHHCCCEEEEEECHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FSPQHAIKNQSSMARSWRWWCNKLTLQSS
CCHHHHHCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRLGVCGVNSEPSSEGTEMDFTIIVDNWRYLLWGTFPDGPLGGAALTVVISIMAGVASAV
CCEEECCCCCCCCCCCCCEEEEEEEECCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
LGTVLGVALAMSRGVWAGILAAVLGLFRAIPVIMLIFWTYFLLPIVFGVDIPEITTVVCA
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LALIASAYLAHAVKAGIMAIGAGQWQAGLSLGFNRWQTLWFIVLPQALRMMVPSFINQWI
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLIKDTSLAYIVGVNELTFLATQVNNRSMVYPMEVFLFVALVYFVLCLALDLLANGLNRR
HHHHCCCEEEEEECHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FSPQHAIKNQSSMARSWRWWCNKLTLQSS
CCHHHHHCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamate [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamate [Periplasm] + H2O = ADP + phosphate + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7551042; 9384377 [H]