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The map label for this gene is yheS [H]

Identifier: 22127840

GI number: 22127840

Start: 4428513

End: 4429085

Strand: Reverse

Name: yheS [H]

Synonym: y3970

Alternate gene names: 22127840

Gene position: 4429085-4428513 (Counterclockwise)

Preceding gene: 22127844

Following gene: 22127839

Centisome position: 96.27

GC content: 53.23

Gene sequence:

>573_bases
ATGATTGTTTTTTCCTCGCTTCAAATTCGACGTGGTACTCGCGTCTTGCTGGACAACGCCACAGCTACGATTAACCCCGG
TCAGAAAGTCGGCCTGGTTGGCAAGAACGGTTGTGGTAAATCGACTCTGCTGGCGTTGCTCAAAGGCGAACTGAGCGCCG
ATGGGGGCAATGTCACATTTCCCAATAACTGGGCACTGGCCTGGGTTAATCAGGAAACCCCGGCACTGGATATCCCGGCG
ATAGAGTATGTTATCGACGGTGACCGCGAATATCGCCAGTTGGAGGCCGAACTTCAGGCTGCCAATGAAAAAAATGATGG
CCATGCCATCGCAACCGTGCACGGTAAGCTGGATGCCATCCATGCCTGGACTATCCAATCGCGTGCGGCCAGTTTGCTCC
ACGGGCTCGGGTTTTCTCAAGAAAAACTACAGCAACCGGTACGTTCATTTTCGGGTGGCTGGCGTATGCGTCTTAATCTG
GCGCAGGCGCTGGTTTGCCGCTCTGATTTACTGCTCTTGGATGAACCAACCACTTGGATTTGGATGCCGTCATCTGGCTG
GAAAAATGGCTGA

Upstream 100 bases:

>100_bases
TACTCAAGTCAGTCATTAGGATGAGTGAACGTGGCTAACCCCTGTAACTTCAAGTGCAAAGGGGATGATAATTTAACATA
TCCTAAACATACGGCACTCT

Downstream 100 bases:

>100_bases
AAAGCTACACCGGTACCTTGGTATTAATTTCCCATGACCGCGATTTCCTTGATCCTATTATCGATAAGATTTTGCATATT
GAACAGCAAACGCTGAATGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MIVFSSLQIRRGTRVLLDNATATINPGQKVGLVGKNGCGKSTLLALLKGELSADGGNVTFPNNWALAWVNQETPALDIPA
IEYVIDGDREYRQLEAELQAANEKNDGHAIATVHGKLDAIHAWTIQSRAASLLHGLGFSQEKLQQPVRSFSGGWRMRLNL
AQALVCRSDLLLLDEPTTWIWMPSSGWKNG

Sequences:

>Translated_190_residues
MIVFSSLQIRRGTRVLLDNATATINPGQKVGLVGKNGCGKSTLLALLKGELSADGGNVTFPNNWALAWVNQETPALDIPA
IEYVIDGDREYRQLEAELQAANEKNDGHAIATVHGKLDAIHAWTIQSRAASLLHGLGFSQEKLQQPVRSFSGGWRMRLNL
AQALVCRSDLLLLDEPTTWIWMPSSGWKNG
>Mature_190_residues
MIVFSSLQIRRGTRVLLDNATATINPGQKVGLVGKNGCGKSTLLALLKGELSADGGNVTFPNNWALAWVNQETPALDIPA
IEYVIDGDREYRQLEAELQAANEKNDGHAIATVHGKLDAIHAWTIQSRAASLLHGLGFSQEKLQQPVRSFSGGWRMRLNL
AQALVCRSDLLLLDEPTTWIWMPSSGWKNG

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=184, Percent_Identity=40.7608695652174, Blast_Score=126, Evalue=1e-29,
Organism=Homo sapiens, GI10947137, Length=174, Percent_Identity=35.0574712643678, Blast_Score=101, Evalue=4e-22,
Organism=Homo sapiens, GI27881506, Length=174, Percent_Identity=35.0574712643678, Blast_Score=101, Evalue=4e-22,
Organism=Homo sapiens, GI69354671, Length=194, Percent_Identity=34.5360824742268, Blast_Score=91, Evalue=6e-19,
Organism=Homo sapiens, GI10947135, Length=194, Percent_Identity=34.5360824742268, Blast_Score=91, Evalue=7e-19,
Organism=Escherichia coli, GI1789751, Length=187, Percent_Identity=80.7486631016043, Blast_Score=317, Evalue=4e-88,
Organism=Escherichia coli, GI1787041, Length=193, Percent_Identity=31.6062176165803, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787182, Length=183, Percent_Identity=30.0546448087432, Blast_Score=82, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17553372, Length=201, Percent_Identity=34.8258706467662, Blast_Score=111, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17555318, Length=186, Percent_Identity=31.7204301075269, Blast_Score=106, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17559834, Length=192, Percent_Identity=34.8958333333333, Blast_Score=103, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6321121, Length=209, Percent_Identity=39.2344497607655, Blast_Score=123, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6320874, Length=189, Percent_Identity=29.1005291005291, Blast_Score=99, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6325030, Length=187, Percent_Identity=31.0160427807487, Blast_Score=79, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24642252, Length=175, Percent_Identity=38.2857142857143, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI18859989, Length=175, Percent_Identity=38.2857142857143, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24666836, Length=196, Percent_Identity=37.7551020408163, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24641342, Length=193, Percent_Identity=36.7875647668394, Blast_Score=97, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 20772; Mature: 20772

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVFSSLQIRRGTRVLLDNATATINPGQKVGLVGKNGCGKSTLLALLKGELSADGGNVTF
CEEECCEEECCCCEEEEECCEEEECCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEC
PNNWALAWVNQETPALDIPAIEYVIDGDREYRQLEAELQAANEKNDGHAIATVHGKLDAI
CCCEEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEE
HAWTIQSRAASLLHGLGFSQEKLQQPVRSFSGGWRMRLNLAQALVCRSDLLLLDEPTTWI
EEEEHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHCCCEEEEECCCEEE
WMPSSGWKNG
EECCCCCCCC
>Mature Secondary Structure
MIVFSSLQIRRGTRVLLDNATATINPGQKVGLVGKNGCGKSTLLALLKGELSADGGNVTF
CEEECCEEECCCCEEEEECCEEEECCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEC
PNNWALAWVNQETPALDIPAIEYVIDGDREYRQLEAELQAANEKNDGHAIATVHGKLDAI
CCCEEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEE
HAWTIQSRAASLLHGLGFSQEKLQQPVRSFSGGWRMRLNLAQALVCRSDLLLLDEPTTWI
EEEEHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHCCCEEEEECCCEEE
WMPSSGWKNG
EECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]