Click here to switch to the map view.

The map label for this gene is iucA1 [H]

Identifier: 22127256

GI number: 22127256

Start: 3725640

End: 3726248

Strand: Direct

Name: iucA1 [H]

Synonym: y3380

Alternate gene names: 22127256

Gene position: 3725640-3726248 (Clockwise)

Preceding gene: 22127255

Following gene: 22127257

Centisome position: 80.98

GC content: 50.41

Gene sequence:

>609_bases
ATGACTATCCCAGTAGAAACCTTAGCAACCGATGTGGCTGCTCAATGTTTCCTCAACGCGCTGATTCGTGAAACCCAGGA
CTGGCAGATCGTTCCGGCAGCGGGCCACCAACCGTACCCACAACTCCACATTCCTCTTTCTTCTTCACACGCTATCCACA
TTGCCTTATGCCATATCTCCCCAACACAGCATCATCACTATCTGTTCCCTGCCTACCTGCATCAGCAGGGTAATGATAGG
CAGGATGATGACACCCCGGTAAAACTCGGGATCGAACAGTTGGTGACGCTTCTGTTGGAGAAGCCAACGGTAAAAGGTGA
GCTGTCTGATGATGTGGTTGCTCGTTTCCGTCAACGGGTGCTAGAAAGTCATGATAATACTCAGCAAGCGATTAATATTC
GTCTGGATTGGCCGTCATTACGCGATAAACCACTTAATTTTGCCCAGGCAGAACAAGGATTACTGGCCGGCCATGCCTTT
CACCCGGCACCGAAATCCCATCAACCTTTTAATGAAAAACAGGCCCAGCGTTATCTCCCGATTTTGCCTCCCGCTTCCCA
CTACGCTGGTTTGCAGTCGATAAACGCTACCTGTGCGGCGATAGCCTAA

Upstream 100 bases:

>100_bases
AAGGAGATTTATTGAAAAATTGTATCATATTCCAATTGATAATGATAACCACTATTGATATAAGAATCGTTCTCAATGGA
TTAATAAGCGACATGACATC

Downstream 100 bases:

>100_bases
AGCTAACGCTACAACACCGGCTGCAACGCTTTGCCAGCGAAAGCGCCCCACAATTACTCGCGCATTTTACCGATGACGTT
TGGCTGCTCCCCATGCACCC

Product: aerobactin synthetase (subunit alpha)

Products: ADP; phosphate; aerobactin

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MTIPVETLATDVAAQCFLNALIRETQDWQIVPAAGHQPYPQLHIPLSSSHAIHIALCHISPTQHHHYLFPAYLHQQGNDR
QDDDTPVKLGIEQLVTLLLEKPTVKGELSDDVVARFRQRVLESHDNTQQAINIRLDWPSLRDKPLNFAQAEQGLLAGHAF
HPAPKSHQPFNEKQAQRYLPILPPASHYAGLQSINATCAAIA

Sequences:

>Translated_202_residues
MTIPVETLATDVAAQCFLNALIRETQDWQIVPAAGHQPYPQLHIPLSSSHAIHIALCHISPTQHHHYLFPAYLHQQGNDR
QDDDTPVKLGIEQLVTLLLEKPTVKGELSDDVVARFRQRVLESHDNTQQAINIRLDWPSLRDKPLNFAQAEQGLLAGHAF
HPAPKSHQPFNEKQAQRYLPILPPASHYAGLQSINATCAAIA
>Mature_201_residues
TIPVETLATDVAAQCFLNALIRETQDWQIVPAAGHQPYPQLHIPLSSSHAIHIALCHISPTQHHHYLFPAYLHQQGNDRQ
DDDTPVKLGIEQLVTLLLEKPTVKGELSDDVVARFRQRVLESHDNTQQAINIRLDWPSLRDKPLNFAQAEQGLLAGHAFH
PAPKSHQPFNEKQAQRYLPILPPASHYAGLQSINATCAAIA

Specific function: Unknown

COG id: COG4264

COG function: function code Q; Siderophore synthetase component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iucA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007310
- InterPro:   IPR022770 [H]

Pfam domain/function: PF06276 FhuF; PF04183 IucA_IucC [H]

EC number: 6.3.2.27

Molecular weight: Translated: 22534; Mature: 22403

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIPVETLATDVAAQCFLNALIRETQDWQIVPAAGHQPYPQLHIPLSSSHAIHIALCHIS
CCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEECCCCCEEEEEEEECC
PTQHHHYLFPAYLHQQGNDRQDDDTPVKLGIEQLVTLLLEKPTVKGELSDDVVARFRQRV
CCCCCCEECHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
LESHDNTQQAINIRLDWPSLRDKPLNFAQAEQGLLAGHAFHPAPKSHQPFNEKQAQRYLP
HHCCCCCCEEEEEEEECCCCCCCCCCHHHHHCCHHCCCCCCCCCCCCCCCCHHHHHHCCC
ILPPASHYAGLQSINATCAAIA
CCCCCHHHHHHHHCCCCCEECC
>Mature Secondary Structure 
TIPVETLATDVAAQCFLNALIRETQDWQIVPAAGHQPYPQLHIPLSSSHAIHIALCHIS
CCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEECCCCCEEEEEEEECC
PTQHHHYLFPAYLHQQGNDRQDDDTPVKLGIEQLVTLLLEKPTVKGELSDDVVARFRQRV
CCCCCCEECHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
LESHDNTQQAINIRLDWPSLRDKPLNFAQAEQGLLAGHAFHPAPKSHQPFNEKQAQRYLP
HHCCCCCCEEEEEEEECCCCCCCCCCHHHHHCCHHCCCCCCCCCCCCCCCCHHHHHHCCC
ILPPASHYAGLQSINATCAAIA
CCCCCHHHHHHHHCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; citrate; N6-acetyl-N6-hydroxylysine

Specific reaction: 4 ATP + citrate + N6-acetyl-N6-hydroxylysine = 4 ADP + 4 phosphate + aerobactin

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8003107 [H]