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The map label for this gene is fepD [C]

Identifier: 22126715

GI number: 22126715

Start: 3140230

End: 3141072

Strand: Reverse

Name: fepD [C]

Synonym: y2839

Alternate gene names: 22126715

Gene position: 3141072-3140230 (Counterclockwise)

Preceding gene: 22126716

Following gene: 22126714

Centisome position: 68.27

GC content: 52.31

Gene sequence:

>843_bases
TTGGTCCATTCGTTTGCCGATGACGTTAACCGCCGTGGTGGTGGGCGCGAGTTTGGGTTTGGCTGGCTTGTTGATGCAAA
CCGTACTGGCGAATCCGTTAGCCAGTCCTTATACCTTGGGGATTTCAGCCGCGGCAGGATTTGGTGCCGCATTATCGATC
ATCACTGGCTTCAGCGTGGGGGGAGTCTTGTCATTAGGCACCCCATTATTGGCTTCACTGATGGCATTACTGGCCTGCCT
GCCCATTTACTTTCTGGGCCAACGGCAGGGGATGACACCGCAAATTCTGGTGTTGAGCGGCATTGTGGTGCTGTTCTTCT
TCCAGTCGTTGCAATCACTCATGTTATTTCGGCCTCACCAGAAGCGATGCAACAAATTGTATTCTGGCTGTTTGGCAGCC
TGCTAAAAGCCAATATGCAGGGGGTGCTAATGACGGGCAGCGTACTGGCTTGTTCACTGGTTATCTGTTTGCAGCAGGCA
TGGCGATTGACCGCGCTTTCAGCGGGGGAGGAGCAAGCGCTAGGTTTGGGGATTAACGTAAGCGCCTTACGTAAGTTAGC
GTTTCTTCTGGCGACCTTGTTGACCGCCGCCTCTGTGTCTTTTGTCGGCACTATCGGCTTTATCGGTTTGGTCGCCCCTC
ACTTCGCCCGTATGTTGGTCGGCGAAGATCAACGCTATCTGATCGGTATTTCGGCACTTTGTGGCAGCCTGCTATTGGTT
CTGGCCTCTATCATTTCCAAACTCATACTGCCAAATGGTGTCGTGCCGATCGGCATTATTATTGCGCTGATCGGTGTCCC
GGTATTGTTCTATTTTGTGACTAAACAGGTGAAACGGGCATGA

Upstream 100 bases:

>100_bases
ATCGATCTGGCCACTGGCGCGGCCAACCTTAGCCCACTTGATGTATTGCGACTGTTTCTGGTGGATTCTTCGCAGCATGA
TGAACTACACCAGATCATTT

Downstream 100 bases:

>100_bases
CGCAACTGACGTTAAAGCACGTCGGCGTCACGCTTCATAAACGCCCACTGCTCACCGATATTTCTCTAACGTGGCCTGCG
GCACAGGTGAGCGGCATTAT

Product: inner membrane permease of iron ABC transporter

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MVHSFADDVNRRGGGREFGFGWLVDANRTGESVSQSLYLGDFSRGRIWCRIIDHHWLQRGGSLVIRHPIIGFTDGITGLP
AHLLSGPTAGDDTANSGVERHCGAVLLPVVAITHVISASPEAMQQIVFWLFGSLLKANMQGVLMTGSVLACSLVICLQQA
WRLTALSAGEEQALGLGINVSALRKLAFLLATLLTAASVSFVGTIGFIGLVAPHFARMLVGEDQRYLIGISALCGSLLLV
LASIISKLILPNGVVPIGIIIALIGVPVLFYFVTKQVKRA

Sequences:

>Translated_280_residues
MVHSFADDVNRRGGGREFGFGWLVDANRTGESVSQSLYLGDFSRGRIWCRIIDHHWLQRGGSLVIRHPIIGFTDGITGLP
AHLLSGPTAGDDTANSGVERHCGAVLLPVVAITHVISASPEAMQQIVFWLFGSLLKANMQGVLMTGSVLACSLVICLQQA
WRLTALSAGEEQALGLGINVSALRKLAFLLATLLTAASVSFVGTIGFIGLVAPHFARMLVGEDQRYLIGISALCGSLLLV
LASIISKLILPNGVVPIGIIIALIGVPVLFYFVTKQVKRA
>Mature_280_residues
MVHSFADDVNRRGGGREFGFGWLVDANRTGESVSQSLYLGDFSRGRIWCRIIDHHWLQRGGSLVIRHPIIGFTDGITGLP
AHLLSGPTAGDDTANSGVERHCGAVLLPVVAITHVISASPEAMQQIVFWLFGSLLKANMQGVLMTGSVLACSLVICLQQA
WRLTALSAGEEQALGLGINVSALRKLAFLLATLLTAASVSFVGTIGFIGLVAPHFARMLVGEDQRYLIGISALCGSLLLV
LASIISKLILPNGVVPIGIIIALIGVPVLFYFVTKQVKRA

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786805, Length=162, Percent_Identity=33.9506172839506, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790741, Length=151, Percent_Identity=34.4370860927152, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790740, Length=211, Percent_Identity=30.8056872037915, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786347, Length=163, Percent_Identity=36.1963190184049, Blast_Score=68, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 29807; Mature: 29807

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVHSFADDVNRRGGGREFGFGWLVDANRTGESVSQSLYLGDFSRGRIWCRIIDHHWLQRG
CCCCHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCEEEEEHHHHHHHHCC
GSLVIRHPIIGFTDGITGLPAHLLSGPTAGDDTANSGVERHCGAVLLPVVAITHVISASP
CCEEEECCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCH
EAMQQIVFWLFGSLLKANMQGVLMTGSVLACSLVICLQQAWRLTALSAGEEQALGLGINV
HHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCH
SALRKLAFLLATLLTAASVSFVGTIGFIGLVAPHFARMLVGEDQRYLIGISALCGSLLLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LASIISKLILPNGVVPIGIIIALIGVPVLFYFVTKQVKRA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVHSFADDVNRRGGGREFGFGWLVDANRTGESVSQSLYLGDFSRGRIWCRIIDHHWLQRG
CCCCHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCEEEEEHHHHHHHHCC
GSLVIRHPIIGFTDGITGLPAHLLSGPTAGDDTANSGVERHCGAVLLPVVAITHVISASP
CCEEEECCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCH
EAMQQIVFWLFGSLLKANMQGVLMTGSVLACSLVICLQQAWRLTALSAGEEQALGLGINV
HHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCH
SALRKLAFLLATLLTAASVSFVGTIGFIGLVAPHFARMLVGEDQRYLIGISALCGSLLLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LASIISKLILPNGVVPIGIIIALIGVPVLFYFVTKQVKRA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]