Click here to switch to the map view.

The map label for this gene is fabH [H]

Identifier: 22126219

GI number: 22126219

Start: 2569240

End: 2569779

Strand: Reverse

Name: fabH [H]

Synonym: y2334

Alternate gene names: 22126219

Gene position: 2569779-2569240 (Counterclockwise)

Preceding gene: 22126220

Following gene: 22126218

Centisome position: 55.86

GC content: 52.04

Gene sequence:

>540_bases
TTGACTGGAATGATGAGGAGATCTTCACTGATCTTCGGTGATGGTGCCGCATGTGCCATTGTGGAACGAGGAGATGGCCG
CAGTGGCATATTAGCCAGTCTGGTTGAAATGTATCCTACGGGCAGTGAGTTATGTGAGATTCGGGCGGGGGGCACACGAT
GCAACCCTCGCTCAGGTATGGATAACGACGATTTCTTATTTCATATGCAGGGCAAGAGGCTGTTCCGACAAGCCTCTGGT
ATCATTGAAGATTATTTCCAGCGTCTATTGGAAAAAAGTGGGCTGACATTAGCGGATATTGCCACGGTAATTCCGCATCA
GGCGAGCCATTTATCGCTGGCGCATATGCGCAAACGCTTACATGTGCCAACAGATGTGCTGGTGGATATCTATCGAGATC
ATGGTAACCAGGTGGCGGCATCGATACCAACCGCATTGCATGCCGCCGTGATGAGCGGGCGCTTTTCGCCGGGTAAACCG
GTGATGCTTATTGGTACCGCAGCAGGGTTGACGCTGGCGGGGATGGTTTTGCTGCCATGA

Upstream 100 bases:

>100_bases
GTGAGCTTTATTTCCGCATTACAGGTGGCTGCGGGGCTACTGAATGCCGGAACTTATCAGCGTATCGCTATTGTTTCAGC
CGATCTGGCATCACGAGGTA

Downstream 100 bases:

>100_bases
GAGCCTTACGATCATGAAAGTCTTAGTGACAGGGGCAACCAGTGGATTGGGGCGCAACGCAGCACAATGGCTGTTGGAGG
CAGGGCACGAGGTCTATGCT

Product: hypothetical protein

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 179; Mature: 178

Protein sequence:

>179_residues
MTGMMRRSSLIFGDGAACAIVERGDGRSGILASLVEMYPTGSELCEIRAGGTRCNPRSGMDNDDFLFHMQGKRLFRQASG
IIEDYFQRLLEKSGLTLADIATVIPHQASHLSLAHMRKRLHVPTDVLVDIYRDHGNQVAASIPTALHAAVMSGRFSPGKP
VMLIGTAAGLTLAGMVLLP

Sequences:

>Translated_179_residues
MTGMMRRSSLIFGDGAACAIVERGDGRSGILASLVEMYPTGSELCEIRAGGTRCNPRSGMDNDDFLFHMQGKRLFRQASG
IIEDYFQRLLEKSGLTLADIATVIPHQASHLSLAHMRKRLHVPTDVLVDIYRDHGNQVAASIPTALHAAVMSGRFSPGKP
VMLIGTAAGLTLAGMVLLP
>Mature_178_residues
TGMMRRSSLIFGDGAACAIVERGDGRSGILASLVEMYPTGSELCEIRAGGTRCNPRSGMDNDDFLFHMQGKRLFRQASGI
IEDYFQRLLEKSGLTLADIATVIPHQASHLSLAHMRKRLHVPTDVLVDIYRDHGNQVAASIPTALHAAVMSGRFSPGKPV
MLIGTAAGLTLAGMVLLP

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=167, Percent_Identity=28.7425149700599, Blast_Score=66, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 19262; Mature: 19131

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGMMRRSSLIFGDGAACAIVERGDGRSGILASLVEMYPTGSELCEIRAGGTRCNPRSGM
CCCCCCCCCEEECCCCEEEEEECCCCCHHHHHHHHHHCCCCHHHEEECCCCCCCCCCCCC
DNDDFLFHMQGKRLFRQASGIIEDYFQRLLEKSGLTLADIATVIPHQASHLSLAHMRKRL
CCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHC
HVPTDVLVDIYRDHGNQVAASIPTALHAAVMSGRFSPGKPVMLIGTAAGLTLAGMVLLP
CCCHHHHHHHHHHCCCEEHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHEEECC
>Mature Secondary Structure 
TGMMRRSSLIFGDGAACAIVERGDGRSGILASLVEMYPTGSELCEIRAGGTRCNPRSGM
CCCCCCCCEEECCCCEEEEEECCCCCHHHHHHHHHHCCCCHHHEEECCCCCCCCCCCCC
DNDDFLFHMQGKRLFRQASGIIEDYFQRLLEKSGLTLADIATVIPHQASHLSLAHMRKRL
CCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHC
HVPTDVLVDIYRDHGNQVAASIPTALHAAVMSGRFSPGKPVMLIGTAAGLTLAGMVLLP
CCCHHHHHHHHHHCCCEEHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA