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The map label for this gene is fabH [H]

Identifier: 22126220

GI number: 22126220

Start: 2569739

End: 2570248

Strand: Reverse

Name: fabH [H]

Synonym: y2335

Alternate gene names: 22126220

Gene position: 2570248-2569739 (Counterclockwise)

Preceding gene: 22126222

Following gene: 22126219

Centisome position: 55.87

GC content: 49.8

Gene sequence:

>510_bases
ATGTCGACATTATTAATTTCAGCACCTCATCTGGCGTTCAAAATTATCGCCACAGGGGTATCGTTACCCCCTGATAGGGT
GGAATCCTCGACGTTGGATCGTAAACTCAATAAGCCTGTCGGTTATGTAGAACAACGTTCTGGTGTCCGGCATCGTTATC
ATGCGACGGCAGATGCTAACCAAGCTGAGTTAGCGGCGGCAGCACTGCATGATGCCCTTGAGCGCCATGGGATCAATCCT
TCCTCAATCGATTTATTAATATCAGCCTCGGCTATTGCCTACCAGGCCCTACCGTGCACGGCGGTGCATATTCTCAAAAT
AGCGGGTCTGGCGCCTCGCATTGCTGGGTTTGATATCAATAGCAGTTGCGTGAGCTTTATTTCCGCATTACAGGTGGCTG
CGGGGCTACTGAATGCCGGAACTTATCAGCGTATCGCTATTGTTTCAGCCGATCTGGCATCACGAGGTATTGACTGGAAT
GATGAGGAGATCTTCACTGATCTTCGGTGA

Upstream 100 bases:

>100_bases
TTTTCGTTCCCCAATAATTAGGGGCCGCCAAAGGGAGATTTCTCCCCAGCCACATACTGGCAATTCACGTTTCAAGCGCT
AAAAAGGTATCTATCTTTCC

Downstream 100 bases:

>100_bases
TGGTGCCGCATGTGCCATTGTGGAACGAGGAGATGGCCGCAGTGGCATATTAGCCAGTCTGGTTGAAATGTATCCTACGG
GCAGTGAGTTATGTGAGATT

Product: hypothetical protein

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 169; Mature: 168

Protein sequence:

>169_residues
MSTLLISAPHLAFKIIATGVSLPPDRVESSTLDRKLNKPVGYVEQRSGVRHRYHATADANQAELAAAALHDALERHGINP
SSIDLLISASAIAYQALPCTAVHILKIAGLAPRIAGFDINSSCVSFISALQVAAGLLNAGTYQRIAIVSADLASRGIDWN
DEEIFTDLR

Sequences:

>Translated_169_residues
MSTLLISAPHLAFKIIATGVSLPPDRVESSTLDRKLNKPVGYVEQRSGVRHRYHATADANQAELAAAALHDALERHGINP
SSIDLLISASAIAYQALPCTAVHILKIAGLAPRIAGFDINSSCVSFISALQVAAGLLNAGTYQRIAIVSADLASRGIDWN
DEEIFTDLR
>Mature_168_residues
STLLISAPHLAFKIIATGVSLPPDRVESSTLDRKLNKPVGYVEQRSGVRHRYHATADANQAELAAAALHDALERHGINPS
SIDLLISASAIAYQALPCTAVHILKIAGLAPRIAGFDINSSCVSFISALQVAAGLLNAGTYQRIAIVSADLASRGIDWND
EEIFTDLR

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=157, Percent_Identity=28.6624203821656, Blast_Score=65, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 17998; Mature: 17867

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLLISAPHLAFKIIATGVSLPPDRVESSTLDRKLNKPVGYVEQRSGVRHRYHATADAN
CCCEEEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCCEEEECCCCCC
QAELAAAALHDALERHGINPSSIDLLISASAIAYQALPCTAVHILKIAGLAPRIAGFDIN
HHHHHHHHHHHHHHHCCCCCCHHEEEEEHHHHHHHCCCHHHHHHHHHHCCCCHHCCCCCC
SSCVSFISALQVAAGLLNAGTYQRIAIVSADLASRGIDWNDEEIFTDLR
HHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCCCCCHHHHCCCC
>Mature Secondary Structure 
STLLISAPHLAFKIIATGVSLPPDRVESSTLDRKLNKPVGYVEQRSGVRHRYHATADAN
CCEEEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCCEEEECCCCCC
QAELAAAALHDALERHGINPSSIDLLISASAIAYQALPCTAVHILKIAGLAPRIAGFDIN
HHHHHHHHHHHHHHHCCCCCCHHEEEEEHHHHHHHCCCHHHHHHHHHHCCCCHHCCCCCC
SSCVSFISALQVAAGLLNAGTYQRIAIVSADLASRGIDWNDEEIFTDLR
HHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]