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The map label for this gene is terC [H]

Identifier: 22124472

GI number: 22124472

Start: 624842

End: 625792

Strand: Direct

Name: terC [H]

Synonym: y0558

Alternate gene names: 22124472

Gene position: 624842-625792 (Clockwise)

Preceding gene: 22124471

Following gene: 22124473

Centisome position: 13.58

GC content: 48.69

Gene sequence:

>951_bases
ATGCACCGCCATGATAAGCCAATCTCTCTGAAAAGTGCGGCGTTGTGGTCTCTCTTCTGGGTCGCCATCGCTTTTGTATT
CGCAGGCTTCCTTTACCTGCATCACGGTGCTGAGGCAGCCAGTTTGTTTGTTACTGGGTATGCGCTTGAAAAAGTGTTAT
CCATTGATAACCTGTTTGTCATGATGGCTATTTTCTCTTGGTTTGCGGTACCAGACCGTTTGCGCTATCGCGTACTGTAT
TGGGGGATTATCGGGGCTATCGTTTTCCGTGGCATTTTCGTCGCCATTGGTACGGGCTTGCTGATGCTAGGGCCGTGGGT
TGAGGTTGTCTTCGCGATAGTTGTTGCCTGGACGGCAGTAATGATGCTGAGAAAAGGCGATGATGACGACGCCATTGAGG
ATTATTCCCAACATATCGCCTATCGTTTAGTGAAGCGTTTCTTCCCTATTTGGCCAAAATTGAGAGGCAATGCCTTTATA
TTGAGCCAGAAAGAGGTTGATGCAGAACTGGCTAAACCTGAAAATGCGGATGTGCAAGTAGGCCGTAAAGGCGGTGTTGC
ACGTTATGCCACGCCATTGATGCTCTGTTTGGCCGTGGTTGAACTGTCAGATGTGATGTTTGCTTTTGACTCTGTACCGG
CGGTGATTGCGGTCAGCCGCGAACCGTTGATCGTCTACAGTGCGATGATGTTCGCAATCCTTGGCTTGCGTACACTGTAT
TTTGTACTTGAAGCGCTGAAGCAGTATCTCGTCCATCTCGAAAAAGCCGTTATTGTGCTGTTGTTCTTCATCGCCGCTAA
GTTGGGCCTGAATGCATCTGACCACTTTTTCAATCACGGCTATGATATCTCGGCCAATGTTAGCCTGTTCGTGGTCATTG
GTGTACTGGCGATCGGTATTGTTGCCAGCTTCCTGTTCCCTGAAAAGGATTCAAAGGAAGGACAGCACTAA

Upstream 100 bases:

>100_bases
AATTTGAGGAATTATGGAATCCACCCATATTGGCTTTCCCATTGAGACAGTAGCCGTGTTCATCCTGCTTTCTGTCGGTG
CCATTTGTATCGATCTTTTC

Downstream 100 bases:

>100_bases
CGTAGGGTTTTAGAGACCTGATGATGTAAATTGAATTAATACTTAACTACTGAGGAAATGAAAATGGGTGTATCTCTTTC
GAAAGGCGGTAATGTCTCCC

Product: tellurium resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MHRHDKPISLKSAALWSLFWVAIAFVFAGFLYLHHGAEAASLFVTGYALEKVLSIDNLFVMMAIFSWFAVPDRLRYRVLY
WGIIGAIVFRGIFVAIGTGLLMLGPWVEVVFAIVVAWTAVMMLRKGDDDDAIEDYSQHIAYRLVKRFFPIWPKLRGNAFI
LSQKEVDAELAKPENADVQVGRKGGVARYATPLMLCLAVVELSDVMFAFDSVPAVIAVSREPLIVYSAMMFAILGLRTLY
FVLEALKQYLVHLEKAVIVLLFFIAAKLGLNASDHFFNHGYDISANVSLFVVIGVLAIGIVASFLFPEKDSKEGQH

Sequences:

>Translated_316_residues
MHRHDKPISLKSAALWSLFWVAIAFVFAGFLYLHHGAEAASLFVTGYALEKVLSIDNLFVMMAIFSWFAVPDRLRYRVLY
WGIIGAIVFRGIFVAIGTGLLMLGPWVEVVFAIVVAWTAVMMLRKGDDDDAIEDYSQHIAYRLVKRFFPIWPKLRGNAFI
LSQKEVDAELAKPENADVQVGRKGGVARYATPLMLCLAVVELSDVMFAFDSVPAVIAVSREPLIVYSAMMFAILGLRTLY
FVLEALKQYLVHLEKAVIVLLFFIAAKLGLNASDHFFNHGYDISANVSLFVVIGVLAIGIVASFLFPEKDSKEGQH
>Mature_316_residues
MHRHDKPISLKSAALWSLFWVAIAFVFAGFLYLHHGAEAASLFVTGYALEKVLSIDNLFVMMAIFSWFAVPDRLRYRVLY
WGIIGAIVFRGIFVAIGTGLLMLGPWVEVVFAIVVAWTAVMMLRKGDDDDAIEDYSQHIAYRLVKRFFPIWPKLRGNAFI
LSQKEVDAELAKPENADVQVGRKGGVARYATPLMLCLAVVELSDVMFAFDSVPAVIAVSREPLIVYSAMMFAILGLRTLY
FVLEALKQYLVHLEKAVIVLLFFIAAKLGLNASDHFFNHGYDISANVSLFVVIGVLAIGIVASFLFPEKDSKEGQH

Specific function: Could conceivably alter the intracellular level of tellurium in a manner leading to resistance. Alternatively its presence in the membrane may provide a barrier to entry of the tellurium ions [H]

COG id: COG0861

COG function: function code P; Membrane protein TerC, possibly involved in tellurium resistance

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the terC family [H]

Homologues:

Organism=Escherichia coli, GI48994922, Length=324, Percent_Identity=34.5679012345679, Blast_Score=153, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005496
- InterPro:   IPR022369 [H]

Pfam domain/function: PF03741 TerC [H]

EC number: NA

Molecular weight: Translated: 35271; Mature: 35271

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRHDKPISLKSAALWSLFWVAIAFVFAGFLYLHHGAEAASLFVTGYALEKVLSIDNLFV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
MMAIFSWFAVPDRLRYRVLYWGIIGAIVFRGIFVAIGTGLLMLGPWVEVVFAIVVAWTAV
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MMLRKGDDDDAIEDYSQHIAYRLVKRFFPIWPKLRGNAFILSQKEVDAELAKPENADVQV
HHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECHHHHHHHCCCCCCCEEE
GRKGGVARYATPLMLCLAVVELSDVMFAFDSVPAVIAVSREPLIVYSAMMFAILGLRTLY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
FVLEALKQYLVHLEKAVIVLLFFIAAKLGLNASDHFFNHGYDISANVSLFVVIGVLAIGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHH
VASFLFPEKDSKEGQH
HHHHHCCCCCCCCCCC
>Mature Secondary Structure
MHRHDKPISLKSAALWSLFWVAIAFVFAGFLYLHHGAEAASLFVTGYALEKVLSIDNLFV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
MMAIFSWFAVPDRLRYRVLYWGIIGAIVFRGIFVAIGTGLLMLGPWVEVVFAIVVAWTAV
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MMLRKGDDDDAIEDYSQHIAYRLVKRFFPIWPKLRGNAFILSQKEVDAELAKPENADVQV
HHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECHHHHHHHCCCCCCCEEE
GRKGGVARYATPLMLCLAVVELSDVMFAFDSVPAVIAVSREPLIVYSAMMFAILGLRTLY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
FVLEALKQYLVHLEKAVIVLLFFIAAKLGLNASDHFFNHGYDISANVSLFVVIGVLAIGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHH
VASFLFPEKDSKEGQH
HHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3049247 [H]