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The map label for this gene is ung [H]

Identifier: 21910157

GI number: 21910157

Start: 680757

End: 681410

Strand: Direct

Name: ung [H]

Synonym: SpyM3_0621

Alternate gene names: 21910157

Gene position: 680757-681410 (Clockwise)

Preceding gene: 21910156

Following gene: 21910158

Centisome position: 35.82

GC content: 42.81

Gene sequence:

>654_bases
ATGGCTCATTCAATTTGGCATGAGAAAATCAAATCATTTTTGCCGGAGCATTACTACGGTCGCATCAATCACTTTTTAGA
TGAAGCCTATGCTTCCGGTCTTGTCTACCCCCAACGAGAAAATGTCTTTAAAGCCTTACAAGTCACTCCTTTGGAAGAAA
CCAAAGTGTTGATTTTAGGACAAGACCCTTATCATGGCCCCAAACAGGCCCAGGGCTTATCATTTTCAGTTCCAGAAGAG
ATTTCTGCTCCGCCATCCCTTATTAATATTTTAAAAGAATTAGCAGATGACATTGGTCCTCGTGACCATCATGATTTAAG
CACTTGGGCTAGTCAAGGGGTTCTGCTTTTGAATGCTTGCTTAACAGTGCCAGCAGGCCAGGCTAATGGGCATGCAGGCT
TAATATGGGAGCCATTTACAGACGCTGTTATTAAAGTGCTGAATGAGAAAGACAGCCCTGTAGTTTTCATTTTGTGGGGA
GCCTATGCAAGGAAGAAAAAAGCCTTCATTACTAATCCAAAGCACCACATCATCGAGAGCCCTCATCCAAGCCCTTTGTC
ATCTTATCGTGGCTTTTTTGGCAGCAAACCCTTTTCAAGAACCAACGCTATTTTAGAAAAAGAGGGCATGACTGGCGTAG
ATTGGCTAAAATAA

Upstream 100 bases:

>100_bases
ATATCATATTTTCAGGGTCTTTCTATTTAAAATGTGGTAAACTAGATAGAAAAGGACATCGTATTTAACTTAGAAACTGA
CGTGATTAGAAAGGAATCTT

Downstream 100 bases:

>100_bases
GCCAGCCATTTCAACTAAATAGCTTAAGCTAGACATTTTGATACCTTTAATAAGTGAAATGAGTGCAGTAGATTTTTCCT
ATTAAAGAACGTAAGGTCTT

Product: uracil-DNA glycosylase

Products: NA

Alternate protein names: UDG [H]

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MAHSIWHEKIKSFLPEHYYGRINHFLDEAYASGLVYPQRENVFKALQVTPLEETKVLILGQDPYHGPKQAQGLSFSVPEE
ISAPPSLINILKELADDIGPRDHHDLSTWASQGVLLLNACLTVPAGQANGHAGLIWEPFTDAVIKVLNEKDSPVVFILWG
AYARKKKAFITNPKHHIIESPHPSPLSSYRGFFGSKPFSRTNAILEKEGMTGVDWLK

Sequences:

>Translated_217_residues
MAHSIWHEKIKSFLPEHYYGRINHFLDEAYASGLVYPQRENVFKALQVTPLEETKVLILGQDPYHGPKQAQGLSFSVPEE
ISAPPSLINILKELADDIGPRDHHDLSTWASQGVLLLNACLTVPAGQANGHAGLIWEPFTDAVIKVLNEKDSPVVFILWG
AYARKKKAFITNPKHHIIESPHPSPLSSYRGFFGSKPFSRTNAILEKEGMTGVDWLK
>Mature_216_residues
AHSIWHEKIKSFLPEHYYGRINHFLDEAYASGLVYPQRENVFKALQVTPLEETKVLILGQDPYHGPKQAQGLSFSVPEEI
SAPPSLINILKELADDIGPRDHHDLSTWASQGVLLLNACLTVPAGQANGHAGLIWEPFTDAVIKVLNEKDSPVVFILWGA
YARKKKAFITNPKHHIIESPHPSPLSSYRGFFGSKPFSRTNAILEKEGMTGVDWLK

Specific function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine [H]

COG id: COG0692

COG function: function code L; Uracil DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uracil-DNA glycosylase family [H]

Homologues:

Organism=Homo sapiens, GI6224979, Length=213, Percent_Identity=48.8262910798122, Blast_Score=203, Evalue=1e-52,
Organism=Homo sapiens, GI19718751, Length=213, Percent_Identity=48.8262910798122, Blast_Score=202, Evalue=1e-52,
Organism=Escherichia coli, GI1788934, Length=215, Percent_Identity=47.906976744186, Blast_Score=201, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI17556304, Length=215, Percent_Identity=42.3255813953488, Blast_Score=174, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6323620, Length=217, Percent_Identity=40.0921658986175, Blast_Score=140, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002043
- InterPro:   IPR018085
- InterPro:   IPR005122 [H]

Pfam domain/function: PF03167 UDG [H]

EC number: =3.2.2.27 [H]

Molecular weight: Translated: 24244; Mature: 24113

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS00130 U_DNA_GLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHSIWHEKIKSFLPEHYYGRINHFLDEAYASGLVYPQRENVFKALQVTPLEETKVLILG
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEEEEEE
QDPYHGPKQAQGLSFSVPEEISAPPSLINILKELADDIGPRDHHDLSTWASQGVLLLNAC
CCCCCCCHHCCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHEEHHH
LTVPAGQANGHAGLIWEPFTDAVIKVLNEKDSPVVFILWGAYARKKKAFITNPKHHIIES
HHCCCCCCCCCCCEEECHHHHHHHHHHCCCCCCEEEEEECCHHHHCCCEECCCHHHCCCC
PHPSPLSSYRGFFGSKPFSRTNAILEKEGMTGVDWLK
CCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
AHSIWHEKIKSFLPEHYYGRINHFLDEAYASGLVYPQRENVFKALQVTPLEETKVLILG
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEEEEEE
QDPYHGPKQAQGLSFSVPEEISAPPSLINILKELADDIGPRDHHDLSTWASQGVLLLNAC
CCCCCCCHHCCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHEEHHH
LTVPAGQANGHAGLIWEPFTDAVIKVLNEKDSPVVFILWGAYARKKKAFITNPKHHIIES
HHCCCCCCCCCCCEEECHHHHHHHHHHCCCCCCEEEEEECCHHHHCCCEECCCHHHCCCC
PHPSPLSSYRGFFGSKPFSRTNAILEKEGMTGVDWLK
CCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]