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The map label for this gene is capA [H]

Identifier: 21910087

GI number: 21910087

Start: 606213

End: 607394

Strand: Direct

Name: capA [H]

Synonym: SpyM3_0551

Alternate gene names: 21910087

Gene position: 606213-607394 (Clockwise)

Preceding gene: 21910086

Following gene: 21910088

Centisome position: 31.9

GC content: 37.56

Gene sequence:

>1182_bases
ATGCAATACAAAAAAACGATGGCAACAGTTGTTGCTCTTATCGTCGCACTTTTGCTATTTGGCTTGATTTATGATTTACT
TGGGGTTCAAAAAAATAAGCTAGCAGCTCAAAAATCTGCTCAGCCAAAGGTCAAAACAGCGCGTGTTGTAGCTAATGGCG
ACATTTTAATTCATGATATTCTCTACATGAGTGCTAGAAAAGCTGACGATACCTATGATTTCACTCCTTATTTTGAATAT
GTTAAGGACTGGATTAGCGGTGCTGACTTAGCTATTGGAGATTATGAAGGGACCATTAGCCCAGATTATCCCTTAGCAGG
CTATCCCTTATTCAATGCTCCAGAAGAGATTGCAGGTGCTCTGAAAAATACTGGCTATGATGTAGTCGATTTAGCCCATA
ATCATATCTTAGATTCCCAATTAGACGGTGCCCTTAACACTAAAAAGGTTTTTCATCAATTAGGTATAGACAGTATTGGC
ATCTATGACAAGGATCGTTCAAAAGAATCCTTCTTAATTAAAAATGTCAATGGTATCAAAATTGCAATTTTAGGTTATTC
TTATGGTTATAACGGCATGGAGGCCACACTTAGCCAAGAAGACTATGAGAAACACATGTCTGATTTAGATGAAGCTAAGA
TAAAAAAAGAACTTCAGCTAGCTGAAAAAAAGGCTGACGTGACCATTGTCATGCCACAAACGGGAACAGAATATGCCTTA
GAACCGACAGCAGAGCAAAAAGAACTTTACCACAAAATGATTGATTGGGGAGCTGACGTCGTCCTAGGAGGTCATCCGCA
TGTTATTGAACCTTCAGAGACAGTTATAAAAGGTAGGCAAAAGAAATTCATTATTTACTCTATGGGGAATTTTATTTCAA
ATCAGCGGCTTGAAACCGTAGATGATATCTGGACTGAGCGTGGCCTATTGATGGACCTTACTTTTGAGAAAAAAGATAAC
AAAACAAAAATTAAAACAGTTGAGGCCCATCCAACCATGGTTTTAGCCAAAGGTAAAGGCATTGTGGGTAAAGAAGGTTT
TGAATTATACAATTATCGAACAATGGTTTTAGAAGATTTTATCAAAGGTGGAAAATACCACGACAAGATTGATGAGGAAA
CCAAAGCAAAAGTGGCACTTGCCTATCAGGAAATTAATGATTTAGTTAACCTGAAATGGTAA

Upstream 100 bases:

>100_bases
GAAAAGCCTCTATAAGGGCTTTTTTGCTGCAATGAAGGAGGAAAATTTTGAGGCAAGATGTTATAATAGAGAAAAAGGAG
GGTGTGTCTTGATTAAAACT

Downstream 100 bases:

>100_bases
TGTTTGGTGGTTTAGCATCTAACGATAAAAAATAGAGATTAAACTTAATTTTTCCTTGATAAAAAGCAGTTATGGTGCTA
AAATAGTAACGTTGACTAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MQYKKTMATVVALIVALLLFGLIYDLLGVQKNKLAAQKSAQPKVKTARVVANGDILIHDILYMSARKADDTYDFTPYFEY
VKDWISGADLAIGDYEGTISPDYPLAGYPLFNAPEEIAGALKNTGYDVVDLAHNHILDSQLDGALNTKKVFHQLGIDSIG
IYDKDRSKESFLIKNVNGIKIAILGYSYGYNGMEATLSQEDYEKHMSDLDEAKIKKELQLAEKKADVTIVMPQTGTEYAL
EPTAEQKELYHKMIDWGADVVLGGHPHVIEPSETVIKGRQKKFIIYSMGNFISNQRLETVDDIWTERGLLMDLTFEKKDN
KTKIKTVEAHPTMVLAKGKGIVGKEGFELYNYRTMVLEDFIKGGKYHDKIDEETKAKVALAYQEINDLVNLKW

Sequences:

>Translated_393_residues
MQYKKTMATVVALIVALLLFGLIYDLLGVQKNKLAAQKSAQPKVKTARVVANGDILIHDILYMSARKADDTYDFTPYFEY
VKDWISGADLAIGDYEGTISPDYPLAGYPLFNAPEEIAGALKNTGYDVVDLAHNHILDSQLDGALNTKKVFHQLGIDSIG
IYDKDRSKESFLIKNVNGIKIAILGYSYGYNGMEATLSQEDYEKHMSDLDEAKIKKELQLAEKKADVTIVMPQTGTEYAL
EPTAEQKELYHKMIDWGADVVLGGHPHVIEPSETVIKGRQKKFIIYSMGNFISNQRLETVDDIWTERGLLMDLTFEKKDN
KTKIKTVEAHPTMVLAKGKGIVGKEGFELYNYRTMVLEDFIKGGKYHDKIDEETKAKVALAYQEINDLVNLKW
>Mature_393_residues
MQYKKTMATVVALIVALLLFGLIYDLLGVQKNKLAAQKSAQPKVKTARVVANGDILIHDILYMSARKADDTYDFTPYFEY
VKDWISGADLAIGDYEGTISPDYPLAGYPLFNAPEEIAGALKNTGYDVVDLAHNHILDSQLDGALNTKKVFHQLGIDSIG
IYDKDRSKESFLIKNVNGIKIAILGYSYGYNGMEATLSQEDYEKHMSDLDEAKIKKELQLAEKKADVTIVMPQTGTEYAL
EPTAEQKELYHKMIDWGADVVLGGHPHVIEPSETVIKGRQKKFIIYSMGNFISNQRLETVDDIWTERGLLMDLTFEKKDN
KTKIKTVEAHPTMVLAKGKGIVGKEGFELYNYRTMVLEDFIKGGKYHDKIDEETKAKVALAYQEINDLVNLKW

Specific function: Essential for the synthesis of the polyglutamate capsule of B.anthracis which is one of the principal virulence factors during anthrax infection. May form a polyglutamyl synthetase complex together with proteins CapB and CapC [H]

COG id: COG2843

COG function: function code M; Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CapA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019079 [H]

Pfam domain/function: PF09587 PGA_cap [H]

EC number: NA

Molecular weight: Translated: 44222; Mature: 44222

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYKKTMATVVALIVALLLFGLIYDLLGVQKNKLAAQKSAQPKVKTARVVANGDILIHDI
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEEEEECCCEEEHHH
LYMSARKADDTYDFTPYFEYVKDWISGADLAIGDYEGTISPDYPLAGYPLFNAPEEIAGA
HHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHH
LKNTGYDVVDLAHNHILDSQLDGALNTKKVFHQLGIDSIGIYDKDRSKESFLIKNVNGIK
HHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCEE
IAILGYSYGYNGMEATLSQEDYEKHMSDLDEAKIKKELQLAEKKADVTIVMPQTGTEYAL
EEEEEEECCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEE
EPTAEQKELYHKMIDWGADVVLGGHPHVIEPSETVIKGRQKKFIIYSMGNFISNQRLETV
CCCHHHHHHHHHHHHCCCCEEECCCCCEECCCHHHHCCCCCEEEEEECCCHHCCCCHHHH
DDIWTERGLLMDLTFEKKDNKTKIKTVEAHPTMVLAKGKGIVGKEGFELYNYRTMVLEDF
HHHHHCCCEEEEEEECCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCHHHHHHHHHHHH
IKGGKYHDKIDEETKAKVALAYQEINDLVNLKW
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQYKKTMATVVALIVALLLFGLIYDLLGVQKNKLAAQKSAQPKVKTARVVANGDILIHDI
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEEEEECCCEEEHHH
LYMSARKADDTYDFTPYFEYVKDWISGADLAIGDYEGTISPDYPLAGYPLFNAPEEIAGA
HHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHH
LKNTGYDVVDLAHNHILDSQLDGALNTKKVFHQLGIDSIGIYDKDRSKESFLIKNVNGIK
HHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCEE
IAILGYSYGYNGMEATLSQEDYEKHMSDLDEAKIKKELQLAEKKADVTIVMPQTGTEYAL
EEEEEEECCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEE
EPTAEQKELYHKMIDWGADVVLGGHPHVIEPSETVIKGRQKKFIIYSMGNFISNQRLETV
CCCHHHHHHHHHHHHCCCCEEECCCCCEECCCHHHHCCCCCEEEEEECCCHHCCCCHHHH
DDIWTERGLLMDLTFEKKDNKTKIKTVEAHPTMVLAKGKGIVGKEGFELYNYRTMVLEDF
HHHHHCCCEEEEEEECCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCHHHHHHHHHHHH
IKGGKYHDKIDEETKAKVALAYQEINDLVNLKW
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2536679; 10475962; 12004073 [H]