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The map label for this gene is atoB [H]

Identifier: 21909644

GI number: 21909644

Start: 130732

End: 131916

Strand: Direct

Name: atoB [H]

Synonym: SpyM3_0108

Alternate gene names: 21909644

Gene position: 130732-131916 (Clockwise)

Preceding gene: 21909642

Following gene: 21909645

Centisome position: 6.88

GC content: 42.28

Gene sequence:

>1185_bases
ATGACTAAAGAAGTGGTGATCACATCTGCTTATCGTACCCCGATAGGAAATTTTGGAGGAGTCTTTAAATCTTTATCAGC
CGTAGATTTGGGGGTGACAGTTGTTACAAAAATTTTAGCTGATACCGGTCTTAAAAGTGATGCCATTGATGAAGTGATCT
TTGGGAATGTGTTACATGCAGGTCTGGGTCAAAATGTTGCTCGGCAAGTAGCGCTAAATGCGGGGCTTTCTTATGATACC
CCTGCTTTTACGATTGATATGGTCTGTGGTTCTGGCTTAAAAGCAGTTGAGTTAGGTGCTCAAAAGATTCAAACGGGCAA
CGCTGATATTGTTTTAGTCGGTGGTACCGAAAACATGAGTCAAGCACCTTACGTTTTACAAGGCCAACGTTGGGGATCTC
GTATGGGAGATAGTAAAGTAGTAGATACCATGCTTAAAGATGGGTTGAGTGATGCTTTTGCAGGTTATCACATGGGTATA
ACAGCCGAAAATATTGTGCAACAGTATGGACTGACCAGAGAAGAACAAGATGCCTTTGCAGCTGATAGCCAACGTAAAGC
CCAACTTGCCATAGAAAAAGGTCGTTTCAAAGAAGAGATTGCACCTGTCACTATTCCTCAGCGTAAAGGTGAACCTTTAC
TCGTTGATCAAGATGAATACCCTAAATTTGGAACGACAGTGGATAAGTTAGCAAAGTTACGCTCTGCTTTTATCAAAGAT
GAGGGGACAGTAACTGCTGGTAATGCTTCAGGAATCAATGATGGAGCAGCGGCAATTTTATTGATGAGTAAAGAAAAAGC
TGAAGAATTAGGGCTCCCTATTTTAGCTAAAATCACTAGTTATGCAAGTGCAGGTGTAGACCCAAGTATTATGGGCTGCG
GACCAATACCTGCTACGAAAAAGGCTCTTGCAAAGGCTCAGCTGACAATTGATGACATTGATTTGATTGAAGCAAACGAA
GCTTTTGCTGCTCAGGCTTTAGCGGTTTCACGAGACCTTGGTTTTGACAATGAAAAAGTTAATGTCAATGGAGGAGCTAT
TGCTTTGGGTCACCCGATTGGAGCATCAGGTGCTCGTATTTTAGTCACCTTATTAGCAGAAATGGCTAAGCGTGATGTGA
GACATGGATTAGCAACGCTTTGTATTGGTGGTGGCCAAGGTCAAAGTATCATCGTAACAAGATAG

Upstream 100 bases:

>100_bases
TTTAGTTATAGCATATATAAAAAAACGATATTTGTTTATTATAGTTCACATTATATAATAAAAATGTAAGCGTTTCAATA
ATGAAAAAGGAGAAGTTTCT

Downstream 100 bases:

>100_bases
AAGGTAACCGTATGAAAGAGAATAAAAGAATAGCAATAGCAGAAGCTATCAGTCATATTAAAGATGGTGACACGATTATG
GTCGGTGGTTTTATGGCTAA

Product: putative acetyl-CoA acetyltransferase

Products: NA

Alternate protein names: Acetoacetyl-CoA thiolase [H]

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MTKEVVITSAYRTPIGNFGGVFKSLSAVDLGVTVVTKILADTGLKSDAIDEVIFGNVLHAGLGQNVARQVALNAGLSYDT
PAFTIDMVCGSGLKAVELGAQKIQTGNADIVLVGGTENMSQAPYVLQGQRWGSRMGDSKVVDTMLKDGLSDAFAGYHMGI
TAENIVQQYGLTREEQDAFAADSQRKAQLAIEKGRFKEEIAPVTIPQRKGEPLLVDQDEYPKFGTTVDKLAKLRSAFIKD
EGTVTAGNASGINDGAAAILLMSKEKAEELGLPILAKITSYASAGVDPSIMGCGPIPATKKALAKAQLTIDDIDLIEANE
AFAAQALAVSRDLGFDNEKVNVNGGAIALGHPIGASGARILVTLLAEMAKRDVRHGLATLCIGGGQGQSIIVTR

Sequences:

>Translated_394_residues
MTKEVVITSAYRTPIGNFGGVFKSLSAVDLGVTVVTKILADTGLKSDAIDEVIFGNVLHAGLGQNVARQVALNAGLSYDT
PAFTIDMVCGSGLKAVELGAQKIQTGNADIVLVGGTENMSQAPYVLQGQRWGSRMGDSKVVDTMLKDGLSDAFAGYHMGI
TAENIVQQYGLTREEQDAFAADSQRKAQLAIEKGRFKEEIAPVTIPQRKGEPLLVDQDEYPKFGTTVDKLAKLRSAFIKD
EGTVTAGNASGINDGAAAILLMSKEKAEELGLPILAKITSYASAGVDPSIMGCGPIPATKKALAKAQLTIDDIDLIEANE
AFAAQALAVSRDLGFDNEKVNVNGGAIALGHPIGASGARILVTLLAEMAKRDVRHGLATLCIGGGQGQSIIVTR
>Mature_393_residues
TKEVVITSAYRTPIGNFGGVFKSLSAVDLGVTVVTKILADTGLKSDAIDEVIFGNVLHAGLGQNVARQVALNAGLSYDTP
AFTIDMVCGSGLKAVELGAQKIQTGNADIVLVGGTENMSQAPYVLQGQRWGSRMGDSKVVDTMLKDGLSDAFAGYHMGIT
AENIVQQYGLTREEQDAFAADSQRKAQLAIEKGRFKEEIAPVTIPQRKGEPLLVDQDEYPKFGTTVDKLAKLRSAFIKDE
GTVTAGNASGINDGAAAILLMSKEKAEELGLPILAKITSYASAGVDPSIMGCGPIPATKKALAKAQLTIDDIDLIEANEA
FAAQALAVSRDLGFDNEKVNVNGGAIALGHPIGASGARILVTLLAEMAKRDVRHGLATLCIGGGQGQSIIVTR

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiolase family [H]

Homologues:

Organism=Homo sapiens, GI148539872, Length=391, Percent_Identity=49.3606138107417, Blast_Score=382, Evalue=1e-106,
Organism=Homo sapiens, GI167614485, Length=393, Percent_Identity=42.2391857506361, Blast_Score=319, Evalue=3e-87,
Organism=Homo sapiens, GI4557237, Length=393, Percent_Identity=41.2213740458015, Blast_Score=290, Evalue=1e-78,
Organism=Homo sapiens, GI4501853, Length=394, Percent_Identity=42.6395939086294, Blast_Score=268, Evalue=8e-72,
Organism=Homo sapiens, GI4504327, Length=424, Percent_Identity=33.0188679245283, Blast_Score=199, Evalue=5e-51,
Organism=Homo sapiens, GI194353979, Length=393, Percent_Identity=30.7888040712468, Blast_Score=145, Evalue=5e-35,
Organism=Escherichia coli, GI87082165, Length=392, Percent_Identity=55.3571428571429, Blast_Score=432, Evalue=1e-122,
Organism=Escherichia coli, GI1788554, Length=393, Percent_Identity=59.2875318066158, Blast_Score=423, Evalue=1e-119,
Organism=Escherichia coli, GI1787663, Length=400, Percent_Identity=42, Blast_Score=294, Evalue=6e-81,
Organism=Escherichia coli, GI48994986, Length=400, Percent_Identity=44.5, Blast_Score=290, Evalue=9e-80,
Organism=Escherichia coli, GI1788683, Length=410, Percent_Identity=33.9024390243902, Blast_Score=212, Evalue=4e-56,
Organism=Caenorhabditis elegans, GI133906874, Length=393, Percent_Identity=47.0737913486005, Blast_Score=340, Evalue=1e-93,
Organism=Caenorhabditis elegans, GI17535921, Length=394, Percent_Identity=40.6091370558376, Blast_Score=274, Evalue=6e-74,
Organism=Caenorhabditis elegans, GI25147385, Length=392, Percent_Identity=38.7755102040816, Blast_Score=266, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI17551802, Length=422, Percent_Identity=30.8056872037915, Blast_Score=181, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI17535917, Length=395, Percent_Identity=31.1392405063291, Blast_Score=165, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6325229, Length=398, Percent_Identity=44.9748743718593, Blast_Score=313, Evalue=3e-86,
Organism=Saccharomyces cerevisiae, GI6322031, Length=397, Percent_Identity=38.2871536523929, Blast_Score=247, Evalue=2e-66,
Organism=Drosophila melanogaster, GI24655093, Length=391, Percent_Identity=51.9181585677749, Blast_Score=391, Evalue=1e-109,
Organism=Drosophila melanogaster, GI17648125, Length=393, Percent_Identity=42.7480916030534, Blast_Score=310, Evalue=8e-85,
Organism=Drosophila melanogaster, GI24640423, Length=391, Percent_Identity=41.1764705882353, Blast_Score=291, Evalue=5e-79,
Organism=Drosophila melanogaster, GI17137578, Length=430, Percent_Identity=31.8604651162791, Blast_Score=193, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020615
- InterPro:   IPR020610
- InterPro:   IPR020617
- InterPro:   IPR020613
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: =2.3.1.9 [H]

Molecular weight: Translated: 41244; Mature: 41112

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS00737 THIOLASE_2 ; PS00099 THIOLASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKEVVITSAYRTPIGNFGGVFKSLSAVDLGVTVVTKILADTGLKSDAIDEVIFGNVLHA
CCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
GLGQNVARQVALNAGLSYDTPAFTIDMVCGSGLKAVELGAQKIQTGNADIVLVGGTENMS
HCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHCHHHHCCCCCCEEEECCCCCCC
QAPYVLQGQRWGSRMGDSKVVDTMLKDGLSDAFAGYHMGITAENIVQQYGLTREEQDAFA
CCCEEEECCHHCCCCCCHHHHHHHHHHCHHHHHCCEECCCCHHHHHHHHCCCCCHHHHHH
ADSQRKAQLAIEKGRFKEEIAPVTIPQRKGEPLLVDQDEYPKFGTTVDKLAKLRSAFIKD
CCCCHHHHHHHHHCCCHHHCCCEECCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHCC
EGTVTAGNASGINDGAAAILLMSKEKAEELGLPILAKITSYASAGVDPSIMGCGPIPATK
CCCEEECCCCCCCCCCEEEEEECHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCHHH
KALAKAQLTIDDIDLIEANEAFAAQALAVSRDLGFDNEKVNVNGGAIALGHPIGASGARI
HHHHHHHEEECCCCEEECCHHHHHHHHHHHHCCCCCCCEEEECCCEEEECCCCCCCHHHH
LVTLLAEMAKRDVRHGLATLCIGGGQGQSIIVTR
HHHHHHHHHHHHHHHCCEEEEEECCCCCEEEEEC
>Mature Secondary Structure 
TKEVVITSAYRTPIGNFGGVFKSLSAVDLGVTVVTKILADTGLKSDAIDEVIFGNVLHA
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
GLGQNVARQVALNAGLSYDTPAFTIDMVCGSGLKAVELGAQKIQTGNADIVLVGGTENMS
HCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHCHHHHCCCCCCEEEECCCCCCC
QAPYVLQGQRWGSRMGDSKVVDTMLKDGLSDAFAGYHMGITAENIVQQYGLTREEQDAFA
CCCEEEECCHHCCCCCCHHHHHHHHHHCHHHHHCCEECCCCHHHHHHHHCCCCCHHHHHH
ADSQRKAQLAIEKGRFKEEIAPVTIPQRKGEPLLVDQDEYPKFGTTVDKLAKLRSAFIKD
CCCCHHHHHHHHHCCCHHHCCCEECCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHCC
EGTVTAGNASGINDGAAAILLMSKEKAEELGLPILAKITSYASAGVDPSIMGCGPIPATK
CCCEEECCCCCCCCCCEEEEEECHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCHHH
KALAKAQLTIDDIDLIEANEAFAAQALAVSRDLGFDNEKVNVNGGAIALGHPIGASGARI
HHHHHHHEEECCCCEEECCHHHHHHHHHHHHCCCCCCCEEEECCCEEEECCCCCCCHHHH
LVTLLAEMAKRDVRHGLATLCIGGGQGQSIIVTR
HHHHHHHHHHHHHHHCCEEEEEECCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]