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The map label for this gene is atoD.2 [H]

Identifier: 21909645

GI number: 21909645

Start: 131928

End: 132587

Strand: Direct

Name: atoD.2 [H]

Synonym: SpyM3_0109

Alternate gene names: 21909645

Gene position: 131928-132587 (Clockwise)

Preceding gene: 21909644

Following gene: 21909646

Centisome position: 6.94

GC content: 39.85

Gene sequence:

>660_bases
ATGAAAGAGAATAAAAGAATAGCAATAGCAGAAGCTATCAGTCATATTAAAGATGGTGACACGATTATGGTCGGTGGTTT
TATGGCTAATGGAACACCAGAAGCGTTAATTGATGCACTGGTTGACAAAGGCACAAAAGACTTAACCTTGATCTGTAATG
ATGCTGGTTTTGTTGATCGTGGTGTTGGAAAAATGGTGGCTAATCATCAATTCAAAACCATCTATGCAACACATATTGGA
TTAAATAAAGAAGCTGGGCGCCAAATGACTGCCGGTGAAACGACGATTGAGCTCATTCCTCAAGGAACCTTCGCCGAAAA
AATTCGCATCGGAGCTTATGGCATTGGTGGCTTTTACACGCCAACAGGGGTAGGAACCTTAGTGGCAGAAGGCAAGGAAA
CAAAAACCATCAAGGGAAAAACCTATCTCTTAGAATACCCATTTGAGGCAGATGTCGCCTTGATATTTGCTAATAAAGCT
GATGAAATGGGAAATTTACAGTATAGTGGTTCTGAAAATAATTTTAATCAATTGATGGCAGCTTGTGCAAAAACAACAAT
TGTTCAGGCGCGAGAAATAGTACCAGTCGGCACCATACAACCAGAATGCGTTCATACACCACACATTTTTGTAGATTACA
TTGTTAAAGAAGGAGTATAG

Upstream 100 bases:

>100_bases
CAGAAATGGCTAAGCGTGATGTGAGACATGGATTAGCAACGCTTTGTATTGGTGGTGGCCAAGGTCAAAGTATCATCGTA
ACAAGATAGAAGGTAACCGT

Downstream 100 bases:

>100_bases
TTATGGCGGTTGCATTAAGTAAAGAAGAGATTCAAAATCGTATTGCAAAGCGTGTGGCCAAAGAATTAGAAGATGGTACT
TTGGTAAATTTAGGTATTGG

Product: putative acetyl-CoA:acetoacetyl-CoA transferase alpha subunit

Products: NA

Alternate protein names: Acetyl-CoA:acetoacetate-CoA transferase subunit alpha [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MKENKRIAIAEAISHIKDGDTIMVGGFMANGTPEALIDALVDKGTKDLTLICNDAGFVDRGVGKMVANHQFKTIYATHIG
LNKEAGRQMTAGETTIELIPQGTFAEKIRIGAYGIGGFYTPTGVGTLVAEGKETKTIKGKTYLLEYPFEADVALIFANKA
DEMGNLQYSGSENNFNQLMAACAKTTIVQAREIVPVGTIQPECVHTPHIFVDYIVKEGV

Sequences:

>Translated_219_residues
MKENKRIAIAEAISHIKDGDTIMVGGFMANGTPEALIDALVDKGTKDLTLICNDAGFVDRGVGKMVANHQFKTIYATHIG
LNKEAGRQMTAGETTIELIPQGTFAEKIRIGAYGIGGFYTPTGVGTLVAEGKETKTIKGKTYLLEYPFEADVALIFANKA
DEMGNLQYSGSENNFNQLMAACAKTTIVQAREIVPVGTIQPECVHTPHIFVDYIVKEGV
>Mature_219_residues
MKENKRIAIAEAISHIKDGDTIMVGGFMANGTPEALIDALVDKGTKDLTLICNDAGFVDRGVGKMVANHQFKTIYATHIG
LNKEAGRQMTAGETTIELIPQGTFAEKIRIGAYGIGGFYTPTGVGTLVAEGKETKTIKGKTYLLEYPFEADVALIFANKA
DEMGNLQYSGSENNFNQLMAACAKTTIVQAREIVPVGTIQPECVHTPHIFVDYIVKEGV

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=224, Percent_Identity=41.5178571428571, Blast_Score=176, Evalue=1e-44,
Organism=Homo sapiens, GI11545841, Length=224, Percent_Identity=40.625, Blast_Score=156, Evalue=2e-38,
Organism=Escherichia coli, GI1788551, Length=213, Percent_Identity=49.2957746478873, Blast_Score=225, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI17531517, Length=225, Percent_Identity=38.6666666666667, Blast_Score=160, Evalue=6e-40,
Organism=Drosophila melanogaster, GI21358325, Length=224, Percent_Identity=39.7321428571429, Blast_Score=171, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24655794, Length=224, Percent_Identity=39.7321428571429, Blast_Score=171, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.8 [H]

Molecular weight: Translated: 23602; Mature: 23602

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKENKRIAIAEAISHIKDGDTIMVGGFMANGTPEALIDALVDKGTKDLTLICNDAGFVDR
CCCCCEEHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHCCCCCCEEEEECCCCCCHH
GVGKMVANHQFKTIYATHIGLNKEAGRQMTAGETTIELIPQGTFAEKIRIGAYGIGGFYT
CHHHHHHCCCEEEEEEEECCCCHHHCCEEECCCCEEEEECCCCCHHEEEEEEEECCCEEC
PTGVGTLVAEGKETKTIKGKTYLLEYPFEADVALIFANKADEMGNLQYSGSENNFNQLMA
CCCCEEEEECCCCCEEEECCEEEEECCCCCCEEEEEECCCCCCCCEEECCCCCCHHHHHH
ACAKTTIVQAREIVPVGTIQPECVHTPHIFVDYIVKEGV
HHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MKENKRIAIAEAISHIKDGDTIMVGGFMANGTPEALIDALVDKGTKDLTLICNDAGFVDR
CCCCCEEHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHCCCCCCEEEEECCCCCCHH
GVGKMVANHQFKTIYATHIGLNKEAGRQMTAGETTIELIPQGTFAEKIRIGAYGIGGFYT
CHHHHHHCCCEEEEEEEECCCCHHHCCEEECCCCEEEEECCCCCHHEEEEEEEECCCEEC
PTGVGTLVAEGKETKTIKGKTYLLEYPFEADVALIFANKADEMGNLQYSGSENNFNQLMA
CCCCEEEEECCCCCEEEECCEEEEECCCCCCEEEEEECCCCCCCCEEECCCCCCHHHHHH
ACAKTTIVQAREIVPVGTIQPECVHTPHIFVDYIVKEGV
HHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]