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The map label for this gene is yggB [C]

Identifier: 21672702

GI number: 21672702

Start: 494421

End: 495272

Strand: Direct

Name: yggB [C]

Synonym: BUsg437

Alternate gene names: 21672702

Gene position: 494421-495272 (Clockwise)

Preceding gene: 21672701

Following gene: 21672703

Centisome position: 77.08

GC content: 29.23

Gene sequence:

>852_bases
ATGAATGAATTAAATGTAGTAAATGATATTAATCATGCAGGCAATTGGTTAATACGAAATCAAGAATTATTATTTGGATA
TGTAATTAATTTGACATCCGCAATTATAATTTTAATTTCTGGAATGTTTATAGCTAAAATAATATCTAACGGAGTGAATC
AAATATTGATAACACGTCATATAGACGCTACTATTGCTGGTTTCCTTTCTGCATTAATGAGATATATTATCATAACTTTT
ACACTTATTGCGTCACTTGGAAGAATCGGAGTACAAACAACGTCAGTAATTGCTATATTAGGAGCTGCTGGTATGGCAAT
TGGATTAGCACTACAAGGCTCTTTATCTAATTTTGCAGCAGGGGTACTATTAGTAACTTTAAGACCTTTAAAAACAGGAG
AATATGTTAACTTAGGAAATGTGGCAGGGACAGTTTTAAACATTCATATCTTTTATACTACTTTACGAACCTTAGACGGG
AAAATTGTAGTTGTTCCAAATAATAAAATTATTTCTGGAAATATCATTAACTATTCCAGAGAACCTGCGCGTCGTAATGA
ATTTTCTATTAGTGTTTCGTATAACACGGATATTGATTTAGTAATAAAAGTACTTAAAAGGGTAATAGAAAATGAAGATA
GAGTTATGAAAGATCGAGATATTGTGATTGGTTTAAGTGAATTAGCTCCATCTTCTTTAAATTTTATTATTCGATGTTGG
AGCAGCACAGATGAATTAAATGCAGTATATTGGGATTTAATGGTTAAATTCAAGAAAGAATTAGATAAAAACAATATTAA
TATTCCTTATCCTCAAATAGACGTTCATCTTTATAAAAAAAATAAAAATTAG

Upstream 100 bases:

>100_bases
TTTCATCACAATTAATTTAATAATTTTTAAAAAAATATTAATTAAAATAATCTGAATTTCTTAAGAATTATTTAAATCAA
AAAAATAAATAGAGATAAAA

Downstream 100 bases:

>100_bases
TTATTTCTAACTAATACTAGATTGTTGTTTGAACTTCTATTTTATTAAAAATAAGGTATTTATGTTTTTTGTTTACAGAT
CAAATCAAATTGATATTTTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MNELNVVNDINHAGNWLIRNQELLFGYVINLTSAIIILISGMFIAKIISNGVNQILITRHIDATIAGFLSALMRYIIITF
TLIASLGRIGVQTTSVIAILGAAGMAIGLALQGSLSNFAAGVLLVTLRPLKTGEYVNLGNVAGTVLNIHIFYTTLRTLDG
KIVVVPNNKIISGNIINYSREPARRNEFSISVSYNTDIDLVIKVLKRVIENEDRVMKDRDIVIGLSELAPSSLNFIIRCW
SSTDELNAVYWDLMVKFKKELDKNNINIPYPQIDVHLYKKNKN

Sequences:

>Translated_283_residues
MNELNVVNDINHAGNWLIRNQELLFGYVINLTSAIIILISGMFIAKIISNGVNQILITRHIDATIAGFLSALMRYIIITF
TLIASLGRIGVQTTSVIAILGAAGMAIGLALQGSLSNFAAGVLLVTLRPLKTGEYVNLGNVAGTVLNIHIFYTTLRTLDG
KIVVVPNNKIISGNIINYSREPARRNEFSISVSYNTDIDLVIKVLKRVIENEDRVMKDRDIVIGLSELAPSSLNFIIRCW
SSTDELNAVYWDLMVKFKKELDKNNINIPYPQIDVHLYKKNKN
>Mature_283_residues
MNELNVVNDINHAGNWLIRNQELLFGYVINLTSAIIILISGMFIAKIISNGVNQILITRHIDATIAGFLSALMRYIIITF
TLIASLGRIGVQTTSVIAILGAAGMAIGLALQGSLSNFAAGVLLVTLRPLKTGEYVNLGNVAGTVLNIHIFYTTLRTLDG
KIVVVPNNKIISGNIINYSREPARRNEFSISVSYNTDIDLVIKVLKRVIENEDRVMKDRDIVIGLSELAPSSLNFIIRCW
SSTDELNAVYWDLMVKFKKELDKNNINIPYPQIDVHLYKKNKN

Specific function: Unknown

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family

Homologues:

Organism=Escherichia coli, GI1789291, Length=283, Percent_Identity=59.0106007067138, Blast_Score=365, Evalue=1e-102,
Organism=Escherichia coli, GI1786670, Length=267, Percent_Identity=26.2172284644195, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787591, Length=277, Percent_Identity=23.4657039711191, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI2367355, Length=155, Percent_Identity=23.8709677419355, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y437_BUCAP (Q8K9B1)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660769.1
- ProteinModelPortal:   Q8K9B1
- SMR:   Q8K9B1
- EnsemblBacteria:   EBBUCT00000000488
- GeneID:   1005728
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg437
- GeneTree:   EBGT00050000008124
- HOGENOM:   HBG691319
- OMA:   VWTTNDD
- ProtClustDB:   CLSK380368
- BioCyc:   BAPH198804:BUSG437-MONOMER
- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014
- InterPro:   IPR008910

Pfam domain/function: PF00924 MS_channel; PF05552 TM_helix; SSF82689 MscC_channel_C; SSF82861 MscS_transmembr; SSF50182 Sm_like_riboprot

EC number: NA

Molecular weight: Translated: 31428; Mature: 31428

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS01246 UPF0003

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc7ec63c)-; HASH(0xc6bc128)-; HASH(0xc0a3224)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNELNVVNDINHAGNWLIRNQELLFGYVINLTSAIIILISGMFIAKIISNGVNQILITRH
CCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
IDATIAGFLSALMRYIIITFTLIASLGRIGVQTTSVIAILGAAGMAIGLALQGSLSNFAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEEEEECCHHHHHH
GVLLVTLRPLKTGEYVNLGNVAGTVLNIHIFYTTLRTLDGKIVVVPNNKIISGNIINYSR
EEEEEEEECCCCCCEEECCCCCCCEEEEEEEEEEHHHCCCEEEEEECCEEEECCEECCCC
EPARRNEFSISVSYNTDIDLVIKVLKRVIENEDRVMKDRDIVIGLSELAPSSLNFIIRCW
CCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCCEECCCCEEEEHHHHCCCCCEEEEEEE
SSTDELNAVYWDLMVKFKKELDKNNINIPYPQIDVHLYKKNKN
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCH
>Mature Secondary Structure
MNELNVVNDINHAGNWLIRNQELLFGYVINLTSAIIILISGMFIAKIISNGVNQILITRH
CCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
IDATIAGFLSALMRYIIITFTLIASLGRIGVQTTSVIAILGAAGMAIGLALQGSLSNFAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEEEEECCHHHHHH
GVLLVTLRPLKTGEYVNLGNVAGTVLNIHIFYTTLRTLDGKIVVVPNNKIISGNIINYSR
EEEEEEEECCCCCCEEECCCCCCCEEEEEEEEEEHHHCCCEEEEEECCEEEECCEECCCC
EPARRNEFSISVSYNTDIDLVIKVLKRVIENEDRVMKDRDIVIGLSELAPSSLNFIIRCW
CCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCCEECCCCEEEEHHHHCCCCCEEEEEEE
SSTDELNAVYWDLMVKFKKELDKNNINIPYPQIDVHLYKKNKN
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12089438