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The map label for this gene is ffh

Identifier: 21672654

GI number: 21672654

Start: 432204

End: 433556

Strand: Direct

Name: ffh

Synonym: BUsg380

Alternate gene names: 21672654

Gene position: 432204-433556 (Clockwise)

Preceding gene: 21672653

Following gene: 21672655

Centisome position: 67.38

GC content: 25.72

Gene sequence:

>1353_bases
ATGTTTAATAACTTAACTGAACGTCTTTCACAAAGTTTACGTAAAATTATTAATAAAGGAAGACTGACAGAAGAAAATAT
TAAAGATACTATACGAGAAGTAAGAAAAGCACTTTTAGAAGCAGATGTAACACTGTCAGTAATAAAAAAGTTTATACAAA
ATGTTTCAAAAAAAGCAATTGGTCATGAAATAAATAAAAGTTTAACGCCCGGTCAAGAATTTATAAAAATTGTAAAAAAT
GAATTAATTTTATCAATGGGGGAAAAGAACCATGATTTAAATCTTTCTATTCAACCACCAGCAATAATATTAGTCGTAGG
ACTACAAGGAGTGGGAAAAACAACTACTTTAGTAAAATTAGCAAAATGGATTAAAGAAAAATATAAGAAAAAAATATTAA
CAGTATCAACTGATATTTATCGAGCTGCTGCAATTAAACAATTACAGATATTATCTGATCAAGTTAAAATAGATTTTTAT
TTATCTGATACAACTCAAACACCAATAAACATCACAAAAGAAGCGATTGAACATGCAAAATTAAAATTATATGACTTGTT
ATTAATCGATACAGCAGGACGTTTACATATTAATACAGAAATGATGAATGAAATAAATACAATACAAAACATTTCAAAAC
CTATTGAAACATTATTGATAGTAGACTCAATGATGGGTCAAGATGCAATCAACATAGCAAAAAAATTCAGCGCATCTTTA
TCTATATCCGGTATAGTGATAACTAAAACAGATAGTGATGCTAGAAGTGGTGTTGCTTTATCAATTCGTCATATTACTGG
AAAACCAATTAAATTTATAGGAACTGGAGAAAAATTACACCAATTAGAACCATTTCATCCTGAAAGGATAGCTGATAGAA
TTTTAGGAATGAATCAAGTTATATCTCTGATCAAAGATATTGAAGAAAAAGTAAATCAATCTCAAGTAAAAAATTTAACT
AAAAAATTTAGAAAAGGTGATGATTTTAACTTAAATGATTTTTTAATACAACTAAAAGAAATGAAAAATATGGGAAATTT
AAACTATTTTATAGAAAAATTCTCAAAAAATAAAATTCTATCTAACAATCCATTATTAGGCGAAAATAAAAATACTCTAA
ATAGAATAGAAGCAATTATATATTCTATGACTCATAAAGAAAGAATGCATCCAATAATCATTAAAGGTTCTCGAAAACGC
AGAATTGCCTTAGGTTCGGGAACAAAAATTCAAGATGTAAACAAATTATTAAAAAATTTTGATAATATAAAAAAAATAAT
GAAAAAAATAAAAAAAGGAGGAATTGGAAAAATGATTCGAAACATAAGCAATATACTACCGAAAAATTTTTAA

Upstream 100 bases:

>100_bases
GTAAATTAAATTTTTAGATACTCTTTTAGATTTAAAAACATTAATAGTAAATTAAAAAAAAATAATAATTTAATATCAAT
TTAAAAACGAGTAAGAAAAA

Downstream 100 bases:

>100_bases
AAAAGAAATAAACTAATAATTTTTGTTTAATATATAAAACAATACACAATAAATTAAAATTTTTATATTTAAGAGAGGAA
AAAAATGGTACGAATTCGAT

Product: signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MFNNLTERLSQSLRKIINKGRLTEENIKDTIREVRKALLEADVTLSVIKKFIQNVSKKAIGHEINKSLTPGQEFIKIVKN
ELILSMGEKNHDLNLSIQPPAIILVVGLQGVGKTTTLVKLAKWIKEKYKKKILTVSTDIYRAAAIKQLQILSDQVKIDFY
LSDTTQTPINITKEAIEHAKLKLYDLLLIDTAGRLHINTEMMNEINTIQNISKPIETLLIVDSMMGQDAINIAKKFSASL
SISGIVITKTDSDARSGVALSIRHITGKPIKFIGTGEKLHQLEPFHPERIADRILGMNQVISLIKDIEEKVNQSQVKNLT
KKFRKGDDFNLNDFLIQLKEMKNMGNLNYFIEKFSKNKILSNNPLLGENKNTLNRIEAIIYSMTHKERMHPIIIKGSRKR
RIALGSGTKIQDVNKLLKNFDNIKKIMKKIKKGGIGKMIRNISNILPKNF

Sequences:

>Translated_450_residues
MFNNLTERLSQSLRKIINKGRLTEENIKDTIREVRKALLEADVTLSVIKKFIQNVSKKAIGHEINKSLTPGQEFIKIVKN
ELILSMGEKNHDLNLSIQPPAIILVVGLQGVGKTTTLVKLAKWIKEKYKKKILTVSTDIYRAAAIKQLQILSDQVKIDFY
LSDTTQTPINITKEAIEHAKLKLYDLLLIDTAGRLHINTEMMNEINTIQNISKPIETLLIVDSMMGQDAINIAKKFSASL
SISGIVITKTDSDARSGVALSIRHITGKPIKFIGTGEKLHQLEPFHPERIADRILGMNQVISLIKDIEEKVNQSQVKNLT
KKFRKGDDFNLNDFLIQLKEMKNMGNLNYFIEKFSKNKILSNNPLLGENKNTLNRIEAIIYSMTHKERMHPIIIKGSRKR
RIALGSGTKIQDVNKLLKNFDNIKKIMKKIKKGGIGKMIRNISNILPKNF
>Mature_450_residues
MFNNLTERLSQSLRKIINKGRLTEENIKDTIREVRKALLEADVTLSVIKKFIQNVSKKAIGHEINKSLTPGQEFIKIVKN
ELILSMGEKNHDLNLSIQPPAIILVVGLQGVGKTTTLVKLAKWIKEKYKKKILTVSTDIYRAAAIKQLQILSDQVKIDFY
LSDTTQTPINITKEAIEHAKLKLYDLLLIDTAGRLHINTEMMNEINTIQNISKPIETLLIVDSMMGQDAINIAKKFSASL
SISGIVITKTDSDARSGVALSIRHITGKPIKFIGTGEKLHQLEPFHPERIADRILGMNQVISLIKDIEEKVNQSQVKNLT
KKFRKGDDFNLNDFLIQLKEMKNMGNLNYFIEKFSKNKILSNNPLLGENKNTLNRIEAIIYSMTHKERMHPIIIKGSRKR
RIALGSGTKIQDVNKLLKNFDNIKKIMKKIKKGGIGKMIRNISNILPKNF

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family

Homologues:

Organism=Homo sapiens, GI4507215, Length=460, Percent_Identity=29.5652173913043, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI226371618, Length=357, Percent_Identity=30.812324929972, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI23308697, Length=301, Percent_Identity=24.5847176079734, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI295424842, Length=301, Percent_Identity=24.5847176079734, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI89061728, Length=168, Percent_Identity=30.3571428571429, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1788963, Length=450, Percent_Identity=58, Blast_Score=542, Evalue=1e-155,
Organism=Escherichia coli, GI1789874, Length=251, Percent_Identity=33.8645418326693, Blast_Score=143, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17539958, Length=440, Percent_Identity=30, Blast_Score=182, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI193206261, Length=296, Percent_Identity=28.3783783783784, Blast_Score=113, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6325345, Length=395, Percent_Identity=31.6455696202532, Blast_Score=176, Evalue=5e-45,
Organism=Saccharomyces cerevisiae, GI6320498, Length=260, Percent_Identity=23.8461538461538, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI17647949, Length=466, Percent_Identity=26.8240343347639, Blast_Score=159, Evalue=5e-39,
Organism=Drosophila melanogaster, GI24641198, Length=207, Percent_Identity=30.4347826086957, Blast_Score=104, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SRP54_BUCAP (Q8K9F7)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660721.1
- ProteinModelPortal:   Q8K9F7
- SMR:   Q8K9F7
- EnsemblBacteria:   EBBUCT00000000500
- GeneID:   1005777
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg380
- GeneTree:   EBGT00050000007749
- HOGENOM:   HBG562580
- OMA:   IINGSRR
- ProtClustDB:   CLSK315010
- BioCyc:   BAPH198804:BUSG380-MONOMER
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125
- Gene3D:   G3DSA:1.20.120.140
- Gene3D:   G3DSA:1.10.260.30
- PANTHER:   PTHR11564:SF7
- SMART:   SM00382
- SMART:   SM00962
- SMART:   SM00963
- TIGRFAMs:   TIGR00959

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB; SSF47446 Signal_recog_particle_SRP54_M; SSF47364 SRP54

EC number: NA

Molecular weight: Translated: 51018; Mature: 51018

Theoretical pI: Translated: 10.68; Mature: 10.68

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNNLTERLSQSLRKIINKGRLTEENIKDTIREVRKALLEADVTLSVIKKFIQNVSKKAI
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
GHEINKSLTPGQEFIKIVKNELILSMGEKNHDLNLSIQPPAIILVVGLQGVGKTTTLVKL
HHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEEEECCCCCCHHHHHHH
AKWIKEKYKKKILTVSTDIYRAAAIKQLQILSDQVKIDFYLSDTTQTPINITKEAIEHAK
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHH
LKLYDLLLIDTAGRLHINTEMMNEINTIQNISKPIETLLIVDSMMGQDAINIAKKFSASL
HHHHHEEEEECCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCE
SISGIVITKTDSDARSGVALSIRHITGKPIKFIGTGEKLHQLEPFHPERIADRILGMNQV
EEEEEEEEECCCCCCCCEEEEEEECCCCCEEEEECCHHHHCCCCCCHHHHHHHHHCHHHH
ISLIKDIEEKVNQSQVKNLTKKFRKGDDFNLNDFLIQLKEMKNMGNLNYFIEKFSKNKIL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCC
SNNPLLGENKNTLNRIEAIIYSMTHKERMHPIIIKGSRKRRIALGSGTKIQDVNKLLKNF
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECCCCCHHHHHHHHHHH
DNIKKIMKKIKKGGIGKMIRNISNILPKNF
HHHHHHHHHHHHCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFNNLTERLSQSLRKIINKGRLTEENIKDTIREVRKALLEADVTLSVIKKFIQNVSKKAI
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
GHEINKSLTPGQEFIKIVKNELILSMGEKNHDLNLSIQPPAIILVVGLQGVGKTTTLVKL
HHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEEEECCCCCCHHHHHHH
AKWIKEKYKKKILTVSTDIYRAAAIKQLQILSDQVKIDFYLSDTTQTPINITKEAIEHAK
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHH
LKLYDLLLIDTAGRLHINTEMMNEINTIQNISKPIETLLIVDSMMGQDAINIAKKFSASL
HHHHHEEEEECCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCE
SISGIVITKTDSDARSGVALSIRHITGKPIKFIGTGEKLHQLEPFHPERIADRILGMNQV
EEEEEEEEECCCCCCCCEEEEEEECCCCCEEEEECCHHHHCCCCCCHHHHHHHHHCHHHH
ISLIKDIEEKVNQSQVKNLTKKFRKGDDFNLNDFLIQLKEMKNMGNLNYFIEKFSKNKIL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCC
SNNPLLGENKNTLNRIEAIIYSMTHKERMHPIIIKGSRKRRIALGSGTKIQDVNKLLKNF
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECCCCCHHHHHHHHHHH
DNIKKIMKKIKKGGIGKMIRNISNILPKNF
HHHHHHHHHHHHCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12089438