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The map label for this gene is pheA

Identifier: 21672653

GI number: 21672653

Start: 430934

End: 432091

Strand: Direct

Name: pheA

Synonym: BUsg379

Alternate gene names: 21672653

Gene position: 430934-432091 (Clockwise)

Preceding gene: 21672650

Following gene: 21672654

Centisome position: 67.18

GC content: 23.83

Gene sequence:

>1158_bases
ATGCCATCTAAAAATGATTTATTAAGTTTTCGAAGTGAAATCAACAACATCGACAAAAATATTGTTCAATTATTGGCAAA
AAGAAAAAAATTAGTATTAAATATAGCAGAATCTAAAATAAAAAATAATCAACCTATACGAGACATAGAAAGAGAAAAAA
TTTTATTAGAAAAACTAACTAATTTAGGAAAAAAAAATAATTTAAATACTAATTATATAACACGTTTATTCCAATTAATA
ATTGAAGAATCTGTATTAACACAAAAAAAATTATTAAATAAGTTTTGCAATGATAATAATCTTGACCTTGCTAGTTTTTC
TTTTCTTGGTCCTAAAGGTTCTTATTCACATATTGCTGCATCTCAATATGCAGAACAAAATTTCAAAACATGTATTGAAA
ATGCATGTTTAAGTTTTAACGAAGTTATACAATCAGTTGAAAACAATCAAACAGATTATGCTGTTCTACCGATAGAAAAT
AGTTGTTCTGGATTTATTAATGAAATATTTGATATTTTAAAAAAAACAAACTTATTTATTATTGGAGAAATTAACATTTC
GATAAATCATTGCTTACTTGCAATAAAAAAAATAGAGCTTAACAAAATTAAAGCAGTATATAGTCATCCTCAACCATTTC
AACAATGCAGTTATTTTATAAAAAAATTTCCAAATTGGAAAATTCAATATACTAATAGTACTGCAGATGCAATGAAAAAA
ATTGTCAAATACAACATAACAACCAATGCTGCTTTAGGAAGTGAATTAGGAAGTAAAATTTATGGATTAAAGGTATTGTA
CAAAAATTTAGCAAATAAAAAGAAAAATATTACAAGATTTATCTTATTATCAAGAAAACCTGTTAGTATTTCTTCAAAAA
TCCCTACAAAAACAACGTTAATATTCAATACAGGTCAAGAATCAGGCGCTCTCGCTGAAGTATTATTAATCTTGAAAAAG
AATAAATTAATTATGAAAAAATTAACTTCTCAAAATATTTATAAAAATCCATGGGAAGAAATGTTTTATATTGATGTTCA
AGCTAATTTATCATCTTCCTTAATGCAAGAAACTCTTGAAAAAATAGGTAAAATTACTAAATTTATAAAAATTCTAGGTT
GTTATCCAAGTGAAAATATAACACCAATAATCCCATAA

Upstream 100 bases:

>100_bases
ATTTATATAAATATTATTTTTTTTAAAAATAAAAATGTATATTAAAAACATATTTTATTTCAATTTAAAAACACTAAATT
TTTAACAGGTAAAATAAATT

Downstream 100 bases:

>100_bases
CATTGCTTAATTGTAAATTAAATTTTTAGATACTCTTTTAGATTTAAAAACATTAATAGTAAATTAAAAAAAAATAATAA
TTTAATATCAATTTAAAAAC

Product: P-protein

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MPSKNDLLSFRSEINNIDKNIVQLLAKRKKLVLNIAESKIKNNQPIRDIEREKILLEKLTNLGKKNNLNTNYITRLFQLI
IEESVLTQKKLLNKFCNDNNLDLASFSFLGPKGSYSHIAASQYAEQNFKTCIENACLSFNEVIQSVENNQTDYAVLPIEN
SCSGFINEIFDILKKTNLFIIGEINISINHCLLAIKKIELNKIKAVYSHPQPFQQCSYFIKKFPNWKIQYTNSTADAMKK
IVKYNITTNAALGSELGSKIYGLKVLYKNLANKKKNITRFILLSRKPVSISSKIPTKTTLIFNTGQESGALAEVLLILKK
NKLIMKKLTSQNIYKNPWEEMFYIDVQANLSSSLMQETLEKIGKITKFIKILGCYPSENITPIIP

Sequences:

>Translated_385_residues
MPSKNDLLSFRSEINNIDKNIVQLLAKRKKLVLNIAESKIKNNQPIRDIEREKILLEKLTNLGKKNNLNTNYITRLFQLI
IEESVLTQKKLLNKFCNDNNLDLASFSFLGPKGSYSHIAASQYAEQNFKTCIENACLSFNEVIQSVENNQTDYAVLPIEN
SCSGFINEIFDILKKTNLFIIGEINISINHCLLAIKKIELNKIKAVYSHPQPFQQCSYFIKKFPNWKIQYTNSTADAMKK
IVKYNITTNAALGSELGSKIYGLKVLYKNLANKKKNITRFILLSRKPVSISSKIPTKTTLIFNTGQESGALAEVLLILKK
NKLIMKKLTSQNIYKNPWEEMFYIDVQANLSSSLMQETLEKIGKITKFIKILGCYPSENITPIIP
>Mature_384_residues
PSKNDLLSFRSEINNIDKNIVQLLAKRKKLVLNIAESKIKNNQPIRDIEREKILLEKLTNLGKKNNLNTNYITRLFQLII
EESVLTQKKLLNKFCNDNNLDLASFSFLGPKGSYSHIAASQYAEQNFKTCIENACLSFNEVIQSVENNQTDYAVLPIENS
CSGFINEIFDILKKTNLFIIGEINISINHCLLAIKKIELNKIKAVYSHPQPFQQCSYFIKKFPNWKIQYTNSTADAMKKI
VKYNITTNAALGSELGSKIYGLKVLYKNLANKKKNITRFILLSRKPVSISSKIPTKTTLIFNTGQESGALAEVLLILKKN
KLIMKKLTSQNIYKNPWEEMFYIDVQANLSSSLMQETLEKIGKITKFIKILGCYPSENITPIIP

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain

Homologues:

Organism=Escherichia coli, GI1788951, Length=385, Percent_Identity=50.9090909090909, Blast_Score=452, Evalue=1e-128,
Organism=Saccharomyces cerevisiae, GI6324013, Length=325, Percent_Identity=24.9230769230769, Blast_Score=80, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHEA_BUCAP (Q8K9F8)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660720.1
- ProteinModelPortal:   Q8K9F8
- EnsemblBacteria:   EBBUCT00000000438
- GeneID:   1005778
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg379
- GeneTree:   EBGT00050000007936
- HOGENOM:   HBG693866
- OMA:   LESRPIY
- ProtClustDB:   CLSK316081
- BioCyc:   BAPH198804:BUSG379-MONOMER
- GO:   GO:0005737
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010952
- InterPro:   IPR001086
- InterPro:   IPR018528
- Gene3D:   G3DSA:1.20.59.10
- PIRSF:   PIRSF001500
- SMART:   SM00830
- TIGRFAMs:   TIGR01797

Pfam domain/function: PF01817 CM_2; PF00800 PDT; SSF48600 Chorismate_mut

EC number: =5.4.99.5; =4.2.1.51

Molecular weight: Translated: 43889; Mature: 43758

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: PS51168 CHORISMATE_MUT_2; PS00857 PREPHENATE_DEHYDR_1; PS00858 PREPHENATE_DEHYDR_2; PS51171 PREPHENATE_DEHYDR_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSKNDLLSFRSEINNIDKNIVQLLAKRKKLVLNIAESKIKNNQPIRDIEREKILLEKLT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
NLGKKNNLNTNYITRLFQLIIEESVLTQKKLLNKFCNDNNLDLASFSFLGPKGSYSHIAA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHH
SQYAEQNFKTCIENACLSFNEVIQSVENNQTDYAVLPIENSCSGFINEIFDILKKTNLFI
HHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHCCEEE
IGEINISINHCLLAIKKIELNKIKAVYSHPQPFQQCSYFIKKFPNWKIQYTNSTADAMKK
EEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCHHHHHHH
IVKYNITTNAALGSELGSKIYGLKVLYKNLANKKKNITRFILLSRKPVSISSKIPTKTTL
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCEEEE
IFNTGQESGALAEVLLILKKNKLIMKKLTSQNIYKNPWEEMFYIDVQANLSSSLMQETLE
EEECCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHEEEEEEECCHHHHHHHHHHH
KIGKITKFIKILGCYPSENITPIIP
HHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
PSKNDLLSFRSEINNIDKNIVQLLAKRKKLVLNIAESKIKNNQPIRDIEREKILLEKLT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
NLGKKNNLNTNYITRLFQLIIEESVLTQKKLLNKFCNDNNLDLASFSFLGPKGSYSHIAA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHH
SQYAEQNFKTCIENACLSFNEVIQSVENNQTDYAVLPIENSCSGFINEIFDILKKTNLFI
HHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHCCEEE
IGEINISINHCLLAIKKIELNKIKAVYSHPQPFQQCSYFIKKFPNWKIQYTNSTADAMKK
EEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCHHHHHHH
IVKYNITTNAALGSELGSKIYGLKVLYKNLANKKKNITRFILLSRKPVSISSKIPTKTTL
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCEEEE
IFNTGQESGALAEVLLILKKNKLIMKKLTSQNIYKNPWEEMFYIDVQANLSSSLMQETLE
EEECCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHEEEEEEECCHHHHHHHHHHH
KIGKITKFIKILGCYPSENITPIIP
HHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12089438