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The map label for this gene is minC

Identifier: 21672594

GI number: 21672594

Start: 364118

End: 364846

Strand: Reverse

Name: minC

Synonym: BUsg318

Alternate gene names: 21672594

Gene position: 364846-364118 (Counterclockwise)

Preceding gene: 21672596

Following gene: 21672593

Centisome position: 56.88

GC content: 25.51

Gene sequence:

>729_bases
ATGCAAAAAATGCCTATTGAACTTAAAGGTAGCAATTTTACATTTTTAGTACTATATTTAAATACTAACAATGTAGACTT
AATAAGTAAATCACTATACAAAAAAATTCAAGAATATCCTCAATTCTTTAAAAACGTTCCTGTTATTGTGAATGTATCAA
ATTTGCTAAATCAAGTAAATTGGAAAAAAATACAAGAAATTATTATTGAATACGGTTTTTATATTGTAGGTGTCAGTGGA
TGTAAAGATAATTATTTTAAAAAAATTATTGTTGAATCAGGCTTACCTGTTTTGTTAGAAAGTAACACAACTAATACAAA
TAAAGATTTACGTTCTTTTTATCATACTTCTACTTTAAAAAAAACAAAAAATGAACAAAGATTACGAGTTAAAAAAATAG
AAAAAACTCATATTATAAATACACCTGTTCGTTCAGGACAAAAAATCTATGCTAAATATTCTGATTTAGTAGTAATAAAT
AATGTAAGTGCTGGAGCAGAATTAGTTGCAGATGGAAATATTCATGTTTATGGTTCAGTCCGAGGTAGAGTACTTGCTGG
TGCTAATGGAGATATCACAAGTAAAATATTTTGTACCACATTATTTGCTGAATTAATATCAGTATCAGGTCAATATTGGT
TATCAGATCAAATACCATCACATTTTATTGGTAAATCAGCTCAAATTTACTTAAAAAATAAATTTTTAACTATTAATTCT
CTCAGTTAA

Upstream 100 bases:

>100_bases
TATATTATAATTTAATTAAACTTCATTAAGTTTTCAACTTTTTCTAAAAACATAATTTATATTTCATGTGCATATAATTA
AACATTATTGAGCAATATAT

Downstream 100 bases:

>100_bases
TTCTGTTTTTTTAGGAAATTTTATATGACACGGATTATTGTAGTTACTTCAGGGAAAGGAGGTGTAGGTAAAACCACTTC
AAGTGCTGCTATTGCAACTG

Product: cell division inhibitor MinC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MQKMPIELKGSNFTFLVLYLNTNNVDLISKSLYKKIQEYPQFFKNVPVIVNVSNLLNQVNWKKIQEIIIEYGFYIVGVSG
CKDNYFKKIIVESGLPVLLESNTTNTNKDLRSFYHTSTLKKTKNEQRLRVKKIEKTHIINTPVRSGQKIYAKYSDLVVIN
NVSAGAELVADGNIHVYGSVRGRVLAGANGDITSKIFCTTLFAELISVSGQYWLSDQIPSHFIGKSAQIYLKNKFLTINS
LS

Sequences:

>Translated_242_residues
MQKMPIELKGSNFTFLVLYLNTNNVDLISKSLYKKIQEYPQFFKNVPVIVNVSNLLNQVNWKKIQEIIIEYGFYIVGVSG
CKDNYFKKIIVESGLPVLLESNTTNTNKDLRSFYHTSTLKKTKNEQRLRVKKIEKTHIINTPVRSGQKIYAKYSDLVVIN
NVSAGAELVADGNIHVYGSVRGRVLAGANGDITSKIFCTTLFAELISVSGQYWLSDQIPSHFIGKSAQIYLKNKFLTINS
LS
>Mature_242_residues
MQKMPIELKGSNFTFLVLYLNTNNVDLISKSLYKKIQEYPQFFKNVPVIVNVSNLLNQVNWKKIQEIIIEYGFYIVGVSG
CKDNYFKKIIVESGLPVLLESNTTNTNKDLRSFYHTSTLKKTKNEQRLRVKKIEKTHIINTPVRSGQKIYAKYSDLVVIN
NVSAGAELVADGNIHVYGSVRGRVLAGANGDITSKIFCTTLFAELISVSGQYWLSDQIPSHFIGKSAQIYLKNKFLTINS
LS

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minC family

Homologues:

Organism=Escherichia coli, GI1787424, Length=241, Percent_Identity=46.8879668049792, Blast_Score=235, Evalue=2e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MINC_BUCAP (Q8K9L6)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660661.1
- ProteinModelPortal:   Q8K9L6
- EnsemblBacteria:   EBBUCT00000000053
- GeneID:   1005523
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg318
- GeneTree:   EBGT00050000007796
- HOGENOM:   HBG399077
- OMA:   IYARNRD
- ProtClustDB:   CLSK315889
- BioCyc:   BAPH198804:BUSG318-MONOMER
- HAMAP:   MF_00267
- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR007874
- InterPro:   IPR005526
- Gene3D:   G3DSA:2.160.20.70
- TIGRFAMs:   TIGR01222

Pfam domain/function: PF03775 MinC_C; PF05209 MinC_N; SSF63848 MinC_C

EC number: NA

Molecular weight: Translated: 27367; Mature: 27367

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKMPIELKGSNFTFLVLYLNTNNVDLISKSLYKKIQEYPQFFKNVPVIVNVSNLLNQVN
CCCCCEEEECCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHCCCC
WKKIQEIIIEYGFYIVGVSGCKDNYFKKIIVESGLPVLLESNTTNTNKDLRSFYHTSTLK
HHHHHHHHHHHCEEEEEECCCCCHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHH
KTKNEQRLRVKKIEKTHIINTPVRSGQKIYAKYSDLVVINNVSAGAELVADGNIHVYGSV
HCCCHHHHHHHHHHHHEEECCCCCCCCEEEEEECCEEEEECCCCCCEEEECCCEEEEEEE
RGRVLAGANGDITSKIFCTTLFAELISVSGQYWLSDQIPSHFIGKSAQIYLKNKFLTINS
CCEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCHHHCCCCEEEEEEEEEEEEEC
LS
CC
>Mature Secondary Structure
MQKMPIELKGSNFTFLVLYLNTNNVDLISKSLYKKIQEYPQFFKNVPVIVNVSNLLNQVN
CCCCCEEEECCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHCCCC
WKKIQEIIIEYGFYIVGVSGCKDNYFKKIIVESGLPVLLESNTTNTNKDLRSFYHTSTLK
HHHHHHHHHHHCEEEEEECCCCCHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHH
KTKNEQRLRVKKIEKTHIINTPVRSGQKIYAKYSDLVVINNVSAGAELVADGNIHVYGSV
HCCCHHHHHHHHHHHHEEECCCCCCCCEEEEEECCEEEEECCCCCCEEEECCCEEEEEEE
RGRVLAGANGDITSKIFCTTLFAELISVSGQYWLSDQIPSHFIGKSAQIYLKNKFLTINS
CCEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCHHHCCCCEEEEEEEEEEEEEC
LS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438