Click here to switch to the map view.

The map label for this gene is suhB

Identifier: 21672554

GI number: 21672554

Start: 312208

End: 313017

Strand: Reverse

Name: suhB

Synonym: BUsg274

Alternate gene names: 21672554

Gene position: 313017-312208 (Counterclockwise)

Preceding gene: 21672559

Following gene: 21672549

Centisome position: 48.8

GC content: 23.33

Gene sequence:

>810_bases
ATGCATCCCATGTTAAATATTGCCATTCGTGCAATTCGAAAAGGAGGAAACATTATTGTACAAAATTATGATACTCAAAA
ATTTATTAAAGAAGATTTAGATAAAAAGAAAATATTTATTAAAAACATAATGTATAAAACATATAGAATAATTAGTGAAG
TAATTTATAAATCTTATCCTAATCATATCATTTTGAATAAAAATACTGATCTTATAAAAAATGAAAAAAATACTTTATGG
ATTATTAATGAATTAGACGGAAAAAATAATTTCATTAAAAATTTTCCGCATTTTTGTATATCTATTGCTGTTATTATGAA
AAATAATACAGAAATTTCAGTAATATATGATCCTATAAGAAATGATTTATTTACAGCTGTCAAGGGACAAGGTTCACAAT
TAAATGGTTATCGTATTAGATGCAATAATATTAACAGTTTAAATTATAGCACTATAGCTATTAATTTACCTCTTAAACAC
TACGCAAAATCTTTATTTTATTTAAAAATATATAAAAAGTTAATTTTGTCTGGAATTTCTCTTAGATGCACAGGTTCTAC
TCTATTGGATTTAGCATATGTAGCTTCTGGTAGAATAGATTGTTTATTTGATTTTAATCCACAATCCATTAATCTTATAG
CAGGAAAATTACAAGCAAGAGAAGCAGGTTGTTTAACTAGTAAGTTTACTGAAAATAGTGAAAAAAAAAGTGAAAAAGGT
AATTTTTGTACTTCAAATTTAACTAGTAGTTCGAAATTTATGAGATTAATTACTGAAAAAATAAGTCAATGTTACTCTTT
CAATAATTAA

Upstream 100 bases:

>100_bases
TTTAATTAAAAAATATTACAAATATATAAATTATGATATTATAAAAAATAATATATTTTTTTTACAAAAAATTTATTTTT
TTAAAATTTAGGAGAATATA

Downstream 100 bases:

>100_bases
TTAGTTTATGTTATTTATTCACAATACACCATTTTCTATCAATAAAAAAAGCTGCCCAACCTGTAAATTTTCCTTCTTTT
TTAGAGGCAATATATTGCTG

Product: extragenic suppressor protein SuhB

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MHPMLNIAIRAIRKGGNIIVQNYDTQKFIKEDLDKKKIFIKNIMYKTYRIISEVIYKSYPNHIILNKNTDLIKNEKNTLW
IINELDGKNNFIKNFPHFCISIAVIMKNNTEISVIYDPIRNDLFTAVKGQGSQLNGYRIRCNNINSLNYSTIAINLPLKH
YAKSLFYLKIYKKLILSGISLRCTGSTLLDLAYVASGRIDCLFDFNPQSINLIAGKLQAREAGCLTSKFTENSEKKSEKG
NFCTSNLTSSSKFMRLITEKISQCYSFNN

Sequences:

>Translated_269_residues
MHPMLNIAIRAIRKGGNIIVQNYDTQKFIKEDLDKKKIFIKNIMYKTYRIISEVIYKSYPNHIILNKNTDLIKNEKNTLW
IINELDGKNNFIKNFPHFCISIAVIMKNNTEISVIYDPIRNDLFTAVKGQGSQLNGYRIRCNNINSLNYSTIAINLPLKH
YAKSLFYLKIYKKLILSGISLRCTGSTLLDLAYVASGRIDCLFDFNPQSINLIAGKLQAREAGCLTSKFTENSEKKSEKG
NFCTSNLTSSSKFMRLITEKISQCYSFNN
>Mature_269_residues
MHPMLNIAIRAIRKGGNIIVQNYDTQKFIKEDLDKKKIFIKNIMYKTYRIISEVIYKSYPNHIILNKNTDLIKNEKNTLW
IINELDGKNNFIKNFPHFCISIAVIMKNNTEISVIYDPIRNDLFTAVKGQGSQLNGYRIRCNNINSLNYSTIAINLPLKH
YAKSLFYLKIYKKLILSGISLRCTGSTLLDLAYVASGRIDCLFDFNPQSINLIAGKLQAREAGCLTSKFTENSEKKSEKG
NFCTSNLTSSSKFMRLITEKISQCYSFNN

Specific function: Unknown

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family

Homologues:

Organism=Homo sapiens, GI7657236, Length=225, Percent_Identity=25.3333333333333, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI5031789, Length=185, Percent_Identity=23.2432432432432, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI221625487, Length=185, Percent_Identity=23.2432432432432, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI1788882, Length=231, Percent_Identity=44.1558441558442, Blast_Score=217, Evalue=7e-58,
Organism=Caenorhabditis elegans, GI193202570, Length=236, Percent_Identity=20.3389830508475, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193202572, Length=233, Percent_Identity=19.7424892703863, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6321836, Length=229, Percent_Identity=26.2008733624454, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320493, Length=186, Percent_Identity=27.9569892473118, Blast_Score=66, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21357303, Length=236, Percent_Identity=28.3898305084746, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24664922, Length=241, Percent_Identity=28.6307053941909, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI21357329, Length=230, Percent_Identity=26.5217391304348, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24664926, Length=229, Percent_Identity=26.2008733624454, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21357957, Length=242, Percent_Identity=26.8595041322314, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24664918, Length=185, Percent_Identity=31.8918918918919, Blast_Score=77, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SUHB_BUCAP (Q8K9P6)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660621.1
- ProteinModelPortal:   Q8K9P6
- SMR:   Q8K9P6
- EnsemblBacteria:   EBBUCT00000000187
- GeneID:   1005478
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg274
- GeneTree:   EBGT00050000008023
- HOGENOM:   HBG730251
- OMA:   TGFPFKQ
- ProtClustDB:   CLSK315858
- BioCyc:   BAPH198804:BUSG274-MONOMER
- InterPro:   IPR000760
- PANTHER:   PTHR20854
- PRINTS:   PR00377

Pfam domain/function: PF00459 Inositol_P

EC number: =3.1.3.25

Molecular weight: Translated: 30842; Mature: 30842

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: PS00629 IMP_1; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPMLNIAIRAIRKGGNIIVQNYDTQKFIKEDLDKKKIFIKNIMYKTYRIISEVIYKSYP
CCCHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCC
NHIILNKNTDLIKNEKNTLWIINELDGKNNFIKNFPHFCISIAVIMKNNTEISVIYDPIR
CEEEEECCCCCEECCCCEEEEEEECCCCCCHHHHCHHHHEEEEEEEECCCEEEEEECCHH
NDLFTAVKGQGSQLNGYRIRCNNINSLNYSTIAINLPLKHYAKSLFYLKIYKKLILSGIS
HHHHHHHCCCCCCCCCEEEEECCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCE
LRCTGSTLLDLAYVASGRIDCLFDFNPQSINLIAGKLQAREAGCLTSKFTENSEKKSEKG
EEECCHHHHHHHHHHCCCEEEEEECCCCEEEEEEEEHHHHHCCCHHHHHCCCCHHHHCCC
NFCTSNLTSSSKFMRLITEKISQCYSFNN
CEEECCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MHPMLNIAIRAIRKGGNIIVQNYDTQKFIKEDLDKKKIFIKNIMYKTYRIISEVIYKSYP
CCCHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCC
NHIILNKNTDLIKNEKNTLWIINELDGKNNFIKNFPHFCISIAVIMKNNTEISVIYDPIR
CEEEEECCCCCEECCCCEEEEEEECCCCCCHHHHCHHHHEEEEEEEECCCEEEEEECCHH
NDLFTAVKGQGSQLNGYRIRCNNINSLNYSTIAINLPLKHYAKSLFYLKIYKKLILSGIS
HHHHHHHCCCCCCCCCEEEEECCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCE
LRCTGSTLLDLAYVASGRIDCLFDFNPQSINLIAGKLQAREAGCLTSKFTENSEKKSEKG
EEECCHHHHHHHHHHCCCEEEEEECCCCEEEEEEEEHHHHHCCCHHHHHCCCCHHHHCCC
NFCTSNLTSSSKFMRLITEKISQCYSFNN
CEEECCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438