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The map label for this gene is trpD

Identifier: 21672549

GI number: 21672549

Start: 305514

End: 306521

Strand: Reverse

Name: trpD

Synonym: BUsg269

Alternate gene names: 21672549

Gene position: 306521-305514 (Counterclockwise)

Preceding gene: 21672554

Following gene: 21672548

Centisome position: 47.79

GC content: 25.99

Gene sequence:

>1008_bases
ATGCAAAATATTTTTAATAAAATTTATGAATCAAAATCCTTAAATCAAGAGGAAAGCTATCAACTTTTTAAATCAATTGC
ATTAGGTAAAATCAATGAAATACAATTATCATCTATTTTAACAGCAATGCAAATGCATGGTGAATCAGAAAAAGAAATAT
TAGGTGCAATATATGCATTTTCAGAAAGAATGAAATTCTTTCCTAGACCCAATTATATTTTTTCTGATATAGTTGGAACA
GGTGGCGATAGTAAAAATACTATTAATGTCTCCACTTCGAGTGCTTTTGTTGCTGCATCCTGTGGATTTAAAATTATTAA
ACATTGTAACAAAGGAGTTTCAAGTAAATCTGGTTCTTCCGATCTTTTAAATAAATTTAAAATCAACTTAAATACATCTC
TAGAAAATTCTAAAAAAATTTTAGATAAATTAAATATTTGTTTTCTGTTTGCTCCTAAATATCACAGTGTTTTTAAATAT
GCATCTAAAACTCGTAGTATCCTAAAAATTAAAACTATTTTTAATTTACTAGGACCATTTCTTAATCCTTCTCGTCCTCC
TTTGACTTTAATTGGTGTTTATAAAAAAGATTTAGTAAATCCTATGTCTAGAATTTTAAAAAAACTAAAATATCAACGGG
GTATAATTTTACATGGTGATGATACAGATGAAGTTACATTGCACGGTACGACATATATTTCTGAATTATTAAATAATAAA
ATTTATTCGTATGAATTAGAACCAGAGGATTTTGGTATAAAAAGACATTCTAAATCAATATTTGTAGAATATTCACCAGA
AGAAAACTACCATATCATTAAAAAAACAATGCAGGGTAAAGGTGAAAAATTACATGAAGAATTAATTGCAGTTAATGTGG
CATTATTACTAAAAATTTTTGGACACGAAAATTTAAAAGAAAATACAAAAATAGCACTGAAAAAAATTCGCAGTGGAGAC
GTTTATAAACATATAATGCAAGTTTCTAATATGTTGAAAGAAGATTAA

Upstream 100 bases:

>100_bases
AAAATTTAAATTGAATTATTTTAATCAATAGATTATTGTGAAAAATTATCAAGATAATAAAAAATCCCAATTTTTTTAAA
AAATTTTTAAAAGGTCATTC

Downstream 100 bases:

>100_bases
TATGCAAGAAACAATACTAAATAAAATTATAAAAGATAAAATAGATTGGATTAAATATAGAAAAAAAATACAACCATTAA
TTAAATTTAAAAACAAAATT

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MQNIFNKIYESKSLNQEESYQLFKSIALGKINEIQLSSILTAMQMHGESEKEILGAIYAFSERMKFFPRPNYIFSDIVGT
GGDSKNTINVSTSSAFVAASCGFKIIKHCNKGVSSKSGSSDLLNKFKINLNTSLENSKKILDKLNICFLFAPKYHSVFKY
ASKTRSILKIKTIFNLLGPFLNPSRPPLTLIGVYKKDLVNPMSRILKKLKYQRGIILHGDDTDEVTLHGTTYISELLNNK
IYSYELEPEDFGIKRHSKSIFVEYSPEENYHIIKKTMQGKGEKLHEELIAVNVALLLKIFGHENLKENTKIALKKIRSGD
VYKHIMQVSNMLKED

Sequences:

>Translated_335_residues
MQNIFNKIYESKSLNQEESYQLFKSIALGKINEIQLSSILTAMQMHGESEKEILGAIYAFSERMKFFPRPNYIFSDIVGT
GGDSKNTINVSTSSAFVAASCGFKIIKHCNKGVSSKSGSSDLLNKFKINLNTSLENSKKILDKLNICFLFAPKYHSVFKY
ASKTRSILKIKTIFNLLGPFLNPSRPPLTLIGVYKKDLVNPMSRILKKLKYQRGIILHGDDTDEVTLHGTTYISELLNNK
IYSYELEPEDFGIKRHSKSIFVEYSPEENYHIIKKTMQGKGEKLHEELIAVNVALLLKIFGHENLKENTKIALKKIRSGD
VYKHIMQVSNMLKED
>Mature_335_residues
MQNIFNKIYESKSLNQEESYQLFKSIALGKINEIQLSSILTAMQMHGESEKEILGAIYAFSERMKFFPRPNYIFSDIVGT
GGDSKNTINVSTSSAFVAASCGFKIIKHCNKGVSSKSGSSDLLNKFKINLNTSLENSKKILDKLNICFLFAPKYHSVFKY
ASKTRSILKIKTIFNLLGPFLNPSRPPLTLIGVYKKDLVNPMSRILKKLKYQRGIILHGDDTDEVTLHGTTYISELLNNK
IYSYELEPEDFGIKRHSKSIFVEYSPEENYHIIKKTMQGKGEKLHEELIAVNVALLLKIFGHENLKENTKIALKKIRSGD
VYKHIMQVSNMLKED

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=329, Percent_Identity=47.112462006079, Blast_Score=320, Evalue=1e-88,
Organism=Saccharomyces cerevisiae, GI6320561, Length=282, Percent_Identity=35.1063829787234, Blast_Score=126, Evalue=5e-30,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_BUCAP (P42392)

Other databases:

- EMBL:   Z19055
- EMBL:   AE013218
- PIR:   A49897
- RefSeq:   NP_660616.1
- ProteinModelPortal:   P42392
- SMR:   P42392
- EnsemblBacteria:   EBBUCT00000000189
- GeneID:   1005471
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg269
- GeneTree:   EBGT00050000007840
- HOGENOM:   HBG559996
- OMA:   HGNKSAS
- ProtClustDB:   PRK00188
- BioCyc:   BAPH198804:BUSG269-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 38091; Mature: 38091

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNIFNKIYESKSLNQEESYQLFKSIALGKINEIQLSSILTAMQMHGESEKEILGAIYAF
CCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
SERMKFFPRPNYIFSDIVGTGGDSKNTINVSTSSAFVAASCGFKIIKHCNKGVSSKSGSS
HHHHHHCCCCCHHHHHHHCCCCCCCCEEEEECCCCEEHHHHHHHHHHHHCCCCCCCCCCH
DLLNKFKINLNTSLENSKKILDKLNICFLFAPKYHSVFKYASKTRSILKIKTIFNLLGPF
HHHHHEEEEECCCCHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNPSRPPLTLIGVYKKDLVNPMSRILKKLKYQRGIILHGDDTDEVTLHGTTYISELLNNK
CCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEECHHHHHHHHHCCC
IYSYELEPEDFGIKRHSKSIFVEYSPEENYHIIKKTMQGKGEKLHEELIAVNVALLLKIF
EEEEECCCCCCCCEECCCEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
GHENLKENTKIALKKIRSGDVYKHIMQVSNMLKED
CCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQNIFNKIYESKSLNQEESYQLFKSIALGKINEIQLSSILTAMQMHGESEKEILGAIYAF
CCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
SERMKFFPRPNYIFSDIVGTGGDSKNTINVSTSSAFVAASCGFKIIKHCNKGVSSKSGSS
HHHHHHCCCCCHHHHHHHCCCCCCCCEEEEECCCCEEHHHHHHHHHHHHCCCCCCCCCCH
DLLNKFKINLNTSLENSKKILDKLNICFLFAPKYHSVFKYASKTRSILKIKTIFNLLGPF
HHHHHEEEEECCCCHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNPSRPPLTLIGVYKKDLVNPMSRILKKLKYQRGIILHGDDTDEVTLHGTTYISELLNNK
CCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEECHHHHHHHHHCCC
IYSYELEPEDFGIKRHSKSIFVEYSPEENYHIIKKTMQGKGEKLHEELIAVNVALLLKIF
EEEEECCCCCCCCEECCCEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
GHENLKENTKIALKKIRSGDVYKHIMQVSNMLKED
CCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8407819; 12089438