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The map label for this gene is murG

Identifier: 21672495

GI number: 21672495

Start: 238707

End: 239771

Strand: Reverse

Name: murG

Synonym: BUsg210

Alternate gene names: 21672495

Gene position: 239771-238707 (Counterclockwise)

Preceding gene: 21672496

Following gene: 21672494

Centisome position: 37.38

GC content: 27.7

Gene sequence:

>1065_bases
ATGAATTCTAAAAGAATAATAATTTTAGCAGGCGGTAGCGGAGGACATGTTTTTCCAGGTCTTACTATTGCGAAACACTT
AATTAAAAAGGGATGGGATATTAATTGGATAGGTACAAAGAATAAAATAGAATCTGAAATTATTCCAAAATGTAATATTA
AAATTCATTTTATAAAAATTCAAGGACTACGTAATAGTAGCTTAAAAAATTTGATTATGACTCCAATCAATGTATTAAAT
TCTTATCTTCAAGTGAGGAAGATAATAAAAAATTGGATACCGGATATTATTTTAGGAATGGGAGGATACGTATCAGGTCC
TGGCGGATTAGCAGCATGGAGCTGTAAAATTCCTTTTATTTTACATGAACAAAACAAAATTGCAGGGATAACAAACAAAT
TACTTTCTAAAATTTCTACAAAAAATATGCAGGCTTTTTCTGGAACTTTATTAAATGCAGAAATAGTCGGAAATCCTATT
CGTAAAAATATTATAGATATACCACCTCCAATTAAACGTTTCAAAAACAGAAAAGGTCCATTAAGAATTTTAATTATTGG
AGGAAGTCAAGGTGCTTCTATTTTCAATAAAATCCTTCCAAAAATATCATTTTTTTTACAAGAAAAAGCTATTATTTGGC
ATCAATCAGGTAATAATGATTTACAAAAAACTAGAAAAAAATACAAAAAATATAGTACGTATAAACATATAGTCAGCTCT
TTTATAAAAAATATAGCAGAAGCATATGAATGGGCAGATATAATTATATCTCGATCCGGTGCTTTAACAGTAAGTGAAAT
TACTGTAGTAGGATTAGGTGCAATATTCATACCTTATCCTCATAAAGATAAGCAACAATATTTAAATGCAGAAGATCTAG
AAAATAACGGTGCTGCGAAAATTATTGAACAATCAATGTTTACTGCAGAATTAATTATAAAAATATTAAATTCTCTAAAC
AGAGAAAAACTGTTTATAATGGCTAAAAAAGCTTATTCTCTTGGAATTAGAAATTCTACATCAAAAATTTCCAAAATTAT
TCACGATGTTAGCAATAAAATATAA

Upstream 100 bases:

>100_bases
TTCAAGTTTAATTGTTAATTTAATGGCTATTTGTATATTATTAAGAATTGATTTTGAAATACGATTAAGCGAACATCAAG
CTTTTCCTAAAGGCATTTAA

Downstream 100 bases:

>100_bases
ACAATTGCTAACAATACAAATATTAAATATTTTTACTTAAAAAATTAAAAAATGAACATAAATAAGATAAAAAAAAATAA
TTTTTTTAAAGAAAAAAAAA

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MNSKRIIILAGGSGGHVFPGLTIAKHLIKKGWDINWIGTKNKIESEIIPKCNIKIHFIKIQGLRNSSLKNLIMTPINVLN
SYLQVRKIIKNWIPDIILGMGGYVSGPGGLAAWSCKIPFILHEQNKIAGITNKLLSKISTKNMQAFSGTLLNAEIVGNPI
RKNIIDIPPPIKRFKNRKGPLRILIIGGSQGASIFNKILPKISFFLQEKAIIWHQSGNNDLQKTRKKYKKYSTYKHIVSS
FIKNIAEAYEWADIIISRSGALTVSEITVVGLGAIFIPYPHKDKQQYLNAEDLENNGAAKIIEQSMFTAELIIKILNSLN
REKLFIMAKKAYSLGIRNSTSKISKIIHDVSNKI

Sequences:

>Translated_354_residues
MNSKRIIILAGGSGGHVFPGLTIAKHLIKKGWDINWIGTKNKIESEIIPKCNIKIHFIKIQGLRNSSLKNLIMTPINVLN
SYLQVRKIIKNWIPDIILGMGGYVSGPGGLAAWSCKIPFILHEQNKIAGITNKLLSKISTKNMQAFSGTLLNAEIVGNPI
RKNIIDIPPPIKRFKNRKGPLRILIIGGSQGASIFNKILPKISFFLQEKAIIWHQSGNNDLQKTRKKYKKYSTYKHIVSS
FIKNIAEAYEWADIIISRSGALTVSEITVVGLGAIFIPYPHKDKQQYLNAEDLENNGAAKIIEQSMFTAELIIKILNSLN
REKLFIMAKKAYSLGIRNSTSKISKIIHDVSNKI
>Mature_354_residues
MNSKRIIILAGGSGGHVFPGLTIAKHLIKKGWDINWIGTKNKIESEIIPKCNIKIHFIKIQGLRNSSLKNLIMTPINVLN
SYLQVRKIIKNWIPDIILGMGGYVSGPGGLAAWSCKIPFILHEQNKIAGITNKLLSKISTKNMQAFSGTLLNAEIVGNPI
RKNIIDIPPPIKRFKNRKGPLRILIIGGSQGASIFNKILPKISFFLQEKAIIWHQSGNNDLQKTRKKYKKYSTYKHIVSS
FIKNIAEAYEWADIIISRSGALTVSEITVVGLGAIFIPYPHKDKQQYLNAEDLENNGAAKIIEQSMFTAELIIKILNSLN
REKLFIMAKKAYSLGIRNSTSKISKIIHDVSNKI

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=351, Percent_Identity=48.4330484330484, Blast_Score=398, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_BUCAP (Q8K9T4)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660562.1
- ProteinModelPortal:   Q8K9T4
- SMR:   Q8K9T4
- EnsemblBacteria:   EBBUCT00000000068
- GeneID:   1005409
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg210
- GeneTree:   EBGT00050000008039
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- ProtClustDB:   PRK00726
- BioCyc:   BAPH198804:BUSG210-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 39559; Mature: 39559

Theoretical pI: Translated: 10.79; Mature: 10.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSKRIIILAGGSGGHVFPGLTIAKHLIKKGWDINWIGTKNKIESEIIPKCNIKIHFIKI
CCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCHHHHCCCCCCEEEEEEEE
QGLRNSSLKNLIMTPINVLNSYLQVRKIIKNWIPDIILGMGGYVSGPGGLAAWSCKIPFI
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCEE
LHEQNKIAGITNKLLSKISTKNMQAFSGTLLNAEIVGNPIRKNIIDIPPPIKRFKNRKGP
EECCCCHHHHHHHHHHHHHHCCHHHHHCCEEEHHHCCCHHHHCCCCCCCHHHHHCCCCCC
LRILIIGGSQGASIFNKILPKISFFLQEKAIIWHQSGNNDLQKTRKKYKKYSTYKHIVSS
EEEEEEECCCCHHHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
FIKNIAEAYEWADIIISRSGALTVSEITVVGLGAIFIPYPHKDKQQYLNAEDLENNGAAK
HHHHHHHHHHHHHHHEECCCCEEEHHHHEEEECEEEECCCCCCHHHHCCHHHCCCCCHHH
IIEQSMFTAELIIKILNSLNREKLFIMAKKAYSLGIRNSTSKISKIIHDVSNKI
HHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNSKRIIILAGGSGGHVFPGLTIAKHLIKKGWDINWIGTKNKIESEIIPKCNIKIHFIKI
CCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCHHHHCCCCCCEEEEEEEE
QGLRNSSLKNLIMTPINVLNSYLQVRKIIKNWIPDIILGMGGYVSGPGGLAAWSCKIPFI
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCEE
LHEQNKIAGITNKLLSKISTKNMQAFSGTLLNAEIVGNPIRKNIIDIPPPIKRFKNRKGP
EECCCCHHHHHHHHHHHHHHCCHHHHHCCEEEHHHCCCHHHHCCCCCCCHHHHHCCCCCC
LRILIIGGSQGASIFNKILPKISFFLQEKAIIWHQSGNNDLQKTRKKYKKYSTYKHIVSS
EEEEEEECCCCHHHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
FIKNIAEAYEWADIIISRSGALTVSEITVVGLGAIFIPYPHKDKQQYLNAEDLENNGAAK
HHHHHHHHHHHHHHHEECCCCEEEHHHHEEEECEEEECCCCCCHHHHCCHHHCCCCCHHH
IIEQSMFTAELIIKILNSLNREKLFIMAKKAYSLGIRNSTSKISKIIHDVSNKI
HHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12089438