Click here to switch to the map view.

The map label for this gene is coaE

Identifier: 21672483

GI number: 21672483

Start: 222655

End: 223287

Strand: Reverse

Name: coaE

Synonym: BUsg197

Alternate gene names: 21672483

Gene position: 223287-222655 (Counterclockwise)

Preceding gene: 21672488

Following gene: 21672479

Centisome position: 34.81

GC content: 19.75

Gene sequence:

>633_bases
ATGATTTATATTGTAGCACTTACTGGAGGAATTTGTAGCGGAAAAACTACTGTTTCTGATAGATTTAAAAAAATAGGTAT
TAATGTTATTGACACTGATGTAATTGGAAGAAAAATAATAGAAAAAAATAAAAAAATATCAGATTCAATCAAAAAAAAAT
TTGGTAAAAAAATATTAAATAAAGATAATTCAATAAACCGTTTTTTGCTTCGAAATTGTATTTTTAATGAAAAAAAAAGT
AGATTATGGTTAGAAAATATACTACATCCTGAAATTTTAAAAAAAAGTAAAAAAAAGATAAAATTAATACAATCAACATG
GTGTTTATGGGTTGTTCCATTGCTTTTTGAAAAAAAAATACAAAAAAAAGCCAATCGAATACTTTTAATTGATACACCAA
TAAGAATACAAATAAGACGTATGATAAAACGAGATAAAATAAATATTAATGAAGCTAAAAAAATTATTTCTTATCAAGTT
AGAAGAAAAAAAAGAATTTCATTATCAGATGATATTATTTTAAACAAAAATAAAAATATTGAAAAGTTAAGTTTATATAT
TCATTATCTTAATAACTTTTATATATATTTATCAAAACAGAACAATCCAAAAAACATGAAAAAAATAATATAA

Upstream 100 bases:

>100_bases
ATAATATAAAAATATATTAAAATTCTTTTTTTTAATAAAAATTAAATATTTTATATTTCTAATAATTAGAAAATACTCAA
TTTTAAATAAATAAAAAATT

Downstream 100 bases:

>100_bases
CTAATTTTACTAAGAATATAAATTTTCACTTAAAAAAAATCATTTTCTGTAAATCATGAATAATATGACTATTTGGACTA
GGAAAGTTAAAATATTTTAG

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MIYIVALTGGICSGKTTVSDRFKKIGINVIDTDVIGRKIIEKNKKISDSIKKKFGKKILNKDNSINRFLLRNCIFNEKKS
RLWLENILHPEILKKSKKKIKLIQSTWCLWVVPLLFEKKIQKKANRILLIDTPIRIQIRRMIKRDKININEAKKIISYQV
RRKKRISLSDDIILNKNKNIEKLSLYIHYLNNFYIYLSKQNNPKNMKKII

Sequences:

>Translated_210_residues
MIYIVALTGGICSGKTTVSDRFKKIGINVIDTDVIGRKIIEKNKKISDSIKKKFGKKILNKDNSINRFLLRNCIFNEKKS
RLWLENILHPEILKKSKKKIKLIQSTWCLWVVPLLFEKKIQKKANRILLIDTPIRIQIRRMIKRDKININEAKKIISYQV
RRKKRISLSDDIILNKNKNIEKLSLYIHYLNNFYIYLSKQNNPKNMKKII
>Mature_210_residues
MIYIVALTGGICSGKTTVSDRFKKIGINVIDTDVIGRKIIEKNKKISDSIKKKFGKKILNKDNSINRFLLRNCIFNEKKS
RLWLENILHPEILKKSKKKIKLIQSTWCLWVVPLLFEKKIQKKANRILLIDTPIRIQIRRMIKRDKININEAKKIISYQV
RRKKRISLSDDIILNKNKNIEKLSLYIHYLNNFYIYLSKQNNPKNMKKII

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain

Homologues:

Organism=Homo sapiens, GI191252797, Length=181, Percent_Identity=30.939226519337, Blast_Score=92, Evalue=2e-19,
Organism=Homo sapiens, GI191252795, Length=181, Percent_Identity=30.939226519337, Blast_Score=92, Evalue=2e-19,
Organism=Homo sapiens, GI110227605, Length=175, Percent_Identity=25.7142857142857, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI110227603, Length=175, Percent_Identity=25.7142857142857, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI110227601, Length=175, Percent_Identity=25.7142857142857, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI110227607, Length=175, Percent_Identity=25.7142857142857, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI205277394, Length=175, Percent_Identity=25.7142857142857, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI1786292, Length=200, Percent_Identity=37.5, Blast_Score=158, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17554944, Length=188, Percent_Identity=28.1914893617021, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6320402, Length=180, Percent_Identity=31.1111111111111, Blast_Score=79, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24644728, Length=185, Percent_Identity=32.4324324324324, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24658602, Length=163, Percent_Identity=26.9938650306748, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAE_BUCAP (Q8K9U1)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660550.1
- ProteinModelPortal:   Q8K9U1
- SMR:   Q8K9U1
- EnsemblBacteria:   EBBUCT00000000153
- GeneID:   1005394
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg197
- GeneTree:   EBGT00050000007828
- HOGENOM:   HBG650290
- OMA:   IIAREVV
- ProtClustDB:   CLSK315784
- BioCyc:   BAPH198804:BUSG197-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00376
- InterPro:   IPR001977
- TIGRFAMs:   TIGR00152

Pfam domain/function: PF01121 CoaE

EC number: =2.7.1.24

Molecular weight: Translated: 24892; Mature: 24892

Theoretical pI: Translated: 11.09; Mature: 11.09

Prosite motif: PS51219 DPCK; PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYIVALTGGICSGKTTVSDRFKKIGINVIDTDVIGRKIIEKNKKISDSIKKKFGKKILN
CEEEEEECCCCCCCCCHHHHHHHHHCCEEECHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
KDNSINRFLLRNCIFNEKKSRLWLENILHPEILKKSKKKIKLIQSTWCLWVVPLLFEKKI
CCCCHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKKANRILLIDTPIRIQIRRMIKRDKININEAKKIISYQVRRKKRISLSDDIILNKNKNI
HHHCCEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCH
EKLSLYIHYLNNFYIYLSKQNNPKNMKKII
HHHHHHHEECCCEEEEEECCCCHHHHHHCC
>Mature Secondary Structure
MIYIVALTGGICSGKTTVSDRFKKIGINVIDTDVIGRKIIEKNKKISDSIKKKFGKKILN
CEEEEEECCCCCCCCCHHHHHHHHHCCEEECHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
KDNSINRFLLRNCIFNEKKSRLWLENILHPEILKKSKKKIKLIQSTWCLWVVPLLFEKKI
CCCCHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKKANRILLIDTPIRIQIRRMIKRDKININEAKKIISYQVRRKKRISLSDDIILNKNKNI
HHHCCEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCH
EKLSLYIHYLNNFYIYLSKQNNPKNMKKII
HHHHHHHEECCCEEEEEECCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438